Using co-culture microsystem for cell migration under fluid shear stress

C. H. Yeh, S. H. Tsai, L. W. Wu, Y. C. Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study has developed a new method to co-culture the two different cells in the specific gap and the cells migration is observed in the fluid shear stress device. Our strategy is using the capillary principle to seed two different cells separately in the co-culture microchip. Smaller gap sizes (100 μm and 50 μm) would cause the migration phenomenon due to the mutual induction between ECs and SMCs. When the fluid shear stress is raised up to 12 dyne/cm, it restrains both the velocities of the SMCs and ECs migration.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1328-1330
Number of pages3
Publication statusPublished - 2010 Dec 1
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: 2010 Oct 32010 Oct 7

Publication series

Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Volume2

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10-10-0310-10-07

Fingerprint

Microsystems
Shear stress
Fluids
Seed

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Yeh, C. H., Tsai, S. H., Wu, L. W., & Lin, Y. C. (2010). Using co-culture microsystem for cell migration under fluid shear stress. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (pp. 1328-1330). (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Vol. 2).
Yeh, C. H. ; Tsai, S. H. ; Wu, L. W. ; Lin, Y. C. / Using co-culture microsystem for cell migration under fluid shear stress. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 2010. pp. 1328-1330 (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010).
@inproceedings{e1eec440e5de4322a78f8649ae83d64b,
title = "Using co-culture microsystem for cell migration under fluid shear stress",
abstract = "This study has developed a new method to co-culture the two different cells in the specific gap and the cells migration is observed in the fluid shear stress device. Our strategy is using the capillary principle to seed two different cells separately in the co-culture microchip. Smaller gap sizes (100 μm and 50 μm) would cause the migration phenomenon due to the mutual induction between ECs and SMCs. When the fluid shear stress is raised up to 12 dyne/cm, it restrains both the velocities of the SMCs and ECs migration.",
author = "Yeh, {C. H.} and Tsai, {S. H.} and Wu, {L. W.} and Lin, {Y. C.}",
year = "2010",
month = "12",
day = "1",
language = "English",
isbn = "9781618390622",
series = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
pages = "1328--1330",
booktitle = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",

}

Yeh, CH, Tsai, SH, Wu, LW & Lin, YC 2010, Using co-culture microsystem for cell migration under fluid shear stress. in 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010, vol. 2, pp. 1328-1330, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010, Groningen, Netherlands, 10-10-03.

Using co-culture microsystem for cell migration under fluid shear stress. / Yeh, C. H.; Tsai, S. H.; Wu, L. W.; Lin, Y. C.

14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 2010. p. 1328-1330 (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Using co-culture microsystem for cell migration under fluid shear stress

AU - Yeh, C. H.

AU - Tsai, S. H.

AU - Wu, L. W.

AU - Lin, Y. C.

PY - 2010/12/1

Y1 - 2010/12/1

N2 - This study has developed a new method to co-culture the two different cells in the specific gap and the cells migration is observed in the fluid shear stress device. Our strategy is using the capillary principle to seed two different cells separately in the co-culture microchip. Smaller gap sizes (100 μm and 50 μm) would cause the migration phenomenon due to the mutual induction between ECs and SMCs. When the fluid shear stress is raised up to 12 dyne/cm, it restrains both the velocities of the SMCs and ECs migration.

AB - This study has developed a new method to co-culture the two different cells in the specific gap and the cells migration is observed in the fluid shear stress device. Our strategy is using the capillary principle to seed two different cells separately in the co-culture microchip. Smaller gap sizes (100 μm and 50 μm) would cause the migration phenomenon due to the mutual induction between ECs and SMCs. When the fluid shear stress is raised up to 12 dyne/cm, it restrains both the velocities of the SMCs and ECs migration.

UR - http://www.scopus.com/inward/record.url?scp=84884399253&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84884399253&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84884399253

SN - 9781618390622

T3 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010

SP - 1328

EP - 1330

BT - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010

ER -

Yeh CH, Tsai SH, Wu LW, Lin YC. Using co-culture microsystem for cell migration under fluid shear stress. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 2010. p. 1328-1330. (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010).