@article{228ad0ce459b4ec3a9a8f555430db7e5,
title = "Which demographic variables are necessary to correct in neuroimaging studies of serotonin transporter availability? A SPECT study with [123I]ADAM",
abstract = "Previous studies have shown that many demographic variables influence serotonin transporter (SERT) availability as assessed by single photon emission computed tomography (SPECT). The aim of this study was to explore which demographic variables influenced the SERT availability most in a SPECT study with [123I]ADAM. Ninety-five healthy volunteers were recruited. Age, sex, smoking, alcohol intake, educational level, body mass index, seasonal change, and SERT availability were recorded and then analyzed by multivariate linear regression. Age was the only variable that was significantly associated with SERT availability (calculate: (midbrain-cerebellum)/cerebellum). Furthermore, the inverse correlation of age and SERT availability may be present only before the age of 47. Age should be a covariate in SERT-related neuroimaging analyses, particularly in participants under the age of 47 years.",
author = "Chang, {Wei Hung} and Lee, {Lan Ting} and Lee, {I. Hui} and Chi, {Mei Hung} and Chen, {Kao Chin} and Chiu, {Nan Tsing} and Yao, {Wei Jen} and Chen, {Po See} and Yang, {Yen Kuang}",
note = "Funding Information: This study was supported in part by grants from the National Science Council of Taiwan (NSC 93-2314-B-006-107, NSC 97-2314-B-006-006-MY3, NSC 99-NU-E-006-003, NSC 100-2314-B-006-041-MY3, and NSC 101-2314-B-006-065) and the Atomic Energy Council (NSC 93-NU-7-006-004). This research also received funding (D102-35001 and D103-35A09) from the Headquarters of University Advancement at the National Cheng Kung University, which is sponsored by the Ministry of Education, Taiwan, ROC. The funding institutions of this study had no further role in the study design; the collection, analysis and interpretation of data; the writing of the report; or the decision to submit the paper for publication. The authors declare that they have no conflicts of interest. The authors wish to thank Mr. Shih-Hsien Lin, Ms. Tsai Hua Chang, Mr. Chien Ting Lin, Professor Yuan-Hwa Chou from Taipei Veterans General Hospital, and all of the research participants. Publisher Copyright: {\textcopyright} 2015 Elsevier Ireland Ltd.",
year = "2015",
month = mar,
day = "30",
doi = "10.1016/j.pscychresns.2015.01.015",
language = "English",
volume = "231",
pages = "320--324",
journal = "Psychiatry Research - Neuroimaging",
issn = "0925-4927",
publisher = "Elsevier Ireland Ltd",
number = "3",
}