Zebrafish sperm activation through an artificial cilia embedded serpentine microfluidic platform

Bivas Panigrahi, Chang Hung Lu, Neha Ghayal, Chia Yuan Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This work reports an artificial cilia embedded serpentine microfluidic channel for high throughput zebrafish sperm cell activation. With this proposed device, an average of 74.44 ± 6.07 % of the used zebrafish sperm cells was activated within the first 15 seconds of the experiment. which is at least 20 % superior to the currently other available techniques. The μPIV analysis of the flow zone suggests that the curvilinear microchannel initiates an orbital rotation to the flow field whereas artificial cilia motion establishes a local rotation in the center of the flow field. Collectively. both the rotational motion. harness a uniform mixing within the microchannel which is quintessential towards changing the temporal dynamics of the sperm cells' hence promoting the sperm cell activation.

Original languageEnglish
Title of host publication2018 IEEE Micro Electro Mechanical Systems, MEMS 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages10-13
Number of pages4
ISBN (Electronic)9781538647820
DOIs
Publication statusPublished - 2018 Apr 24
Event31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018 - Belfast, United Kingdom
Duration: 2018 Jan 212018 Jan 25

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2018-January
ISSN (Print)1084-6999

Other

Other31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018
CountryUnited Kingdom
CityBelfast
Period18-01-2118-01-25

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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