Characteristics and biological behavior of calcium phosphate duplex coating

  • 歐 亞雨

Student thesis: Master's Thesis


The ability cell surface interaction throughout control of biomaterial’s surface properties is critical Titanium and its alloys widely used dental and orthopedic implant system Titanium is bio-inert material that’s why must be done surface modification Radio-frequency sputtered thin film of calcium phosphate and micro-arc oxidation of titanium dioxide have much interest surface modification We aimed combined these 2 method on pure titanium surface which would be improve bioactivity of implant In this study used four different titanium surfaces (micro-arc oxidation acid etched sandblasted and smooth) and evaluated by in vitro including cell morphology proliferation and differentiation of MG-63cells Surface analysis used SEM/EDS TF-XRD FTIR surface roughness and contact angle measurements The SEM image of that combined coating layer showed homogeneously numerous micro pores with different sizes and hydroxyapatite crystalline structure TF-XRD data showed anatase and rutile phase The all coatings composed of various anatase rutile and HA phases are produced by heat treating at 6000C The average surface roughness value of the MCP was high The highest contact angle was measured on MCP600 specimen The MCP specimen showed higher level of cell proliferation and ALP activity than the other HA coated and heat treated group of specimens This experiments suggests that combined coatings with MAO and Ca-P had well surface properties and cellular activity
Date of Award2014 Jan 23
Original languageEnglish
SupervisorTzer-Min Lee (Supervisor)

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