Development and Validation of Home-based Training for Amblyopia

Abstract

The prevalence of worldwide population with amblyopia is 2-5% Amblyopia affects the daily life and learning ability The human visual system can be developed normally with exposure of clear images on the retina which often drive the development of optic nerves progressively In general the visual acuity progresses gradually with age it is relatively mature until 6 years old The Cambridge Stimulator (CAM) with rotating grating is commonly used in clinic The CAM allows subjects to draw pictures on the grating with occlusion of the dominant eye The CAM usually makes children be uninteresting and parents have to go with their children to a hospital Recently some computer games have been incorporated with CAM training Moreover most of these studies didn’t have long-term tracking and they only used limited assessments This study creates a home-based training on tablet The training is based on CAM and integrated into a game The system integrates with clinical information This study has long-term tracking (six months) and five evaluations are used including visual acuity grating acuity grating contrast transient visual evoked potential and steady-state visual evoked potential Most of subjects have been improved significantly after 2 months training The mean of improvement is 0 14 logMAR

Date of Award	2014 Sept 2
Original language	English
Supervisor	Da-Wei Chang (Supervisor)