Development of a 3D Doppler Ultrasound Imaging System for Peripheral Arterial Disease Screening

  • 陳 元豪

Student thesis: Master's Thesis

Abstract

The study of the peripheral arterial disease (PAD) has gained attention in recent years There are symptoms of intermittent claudication ischemic rest pain and gangrene based on the severity of PAD According to the top ten leading causes of death in Taiwan there are 6 to 12 percent of disease is related to PAD Therefore diagnosis and detection of PAD are important for patients There are four detection methods widely used for diagnosing PAD in clinics including ankle brachial pressure index (ABPI) angiography duplex ultrasonography and magnetic resonance imaging (MRI) The ABPI is a primary diagnostic method to detect PAD Recently it is discussed that the ABPI is used as a reference to diagnose PAD However patients with blood vessel disease distorting the measurement of blood pressure may affect the results of ABPI diagnosis accuracy In this study we proposed a method for PAD screening by using 3D image reconstruction and combining with the Doppler ultrasound In the 3D image reconstruction we use monocycle 25 MHz bipolar pulse signal and the R wave of the Electrocardiography (ECG) as a trigger signal to scan the peripheral artery B-mode images Then the Active Contour Model (ACM) is used to correct the image contour Finally the isosurface function is used to reconstruct 3D image In Doppler ultrasound 5-cycle 7 5 MHz bipolar pulse was used to measure the blood flow velocity of peripheral artery with the Doppler angle of 75 degree and pulse repetition frequency (PRF) of 20 kHz In 3D image reconstruction the system reaches 1 frame/s to reconstruct 3D image and the error of circling blood vessel contour is less than 10% In blood flow velocity measurement the error of proposed imaging system compared with commercial instrument is less than 11% In the results of PAD patients the results show that blood flow velocity appears abnormal is caused by the obstruction of peripheral arterial in the PAD patient The cost of proposed imaging system which is compared with commercial image system is reduced This proposed system enables the PAD screening which can be applied for PAD early detection
Date of Award2014 Aug 22
Original languageEnglish
SupervisorTainsong Chen (Supervisor)

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