Dual-Supplied Electrospinning of Chitosan Nanofibers with Plasma-Synthesized and Surface-Immobilized Silver Nanoparticles

  • 王 致凱

Student thesis: Master's Thesis

Abstract

Plasma-synthesized silver nanoparticles (Ag NPs) were immobilized on the surface of chitosan-based nanofibers fabricated by two kinds of dual-supplied electrospinning processes In the first fabrication approach the dual-supplied electrospinning was conducted by two flows that carried the chitosan and the crosslinking agent separately The two flows were mixed right before the ejection of the electrospinning solutions The second approach involved the use of a lab-made co-axial nozzle that constructed the chitosan nanofiber cores and the poly(ethylene oxide) (PEO) outer sheath which also carried the crosslinking agent and the silver precursor Electrospinning processes were carefully investigated in this research project The resulting chitosan nanofibers with an average fiber diameter as small as about 135 nm were then treated with the argon plasma bombardment Silver precursors the silver nitrate within the chitosan nanofibers were converted to metallic Ag NPs which were immobilized on the surface of these nanofibers Water resistance confirmed these robust chitosan nanofibers as well as the stabilities of surface-immobilized Ag NPs Following antibacterial tests based on the water filtration apparatus were investigated And the antibacterial performance of these electrospun chitosan nanofibers were proportionally enhanced by the population of the surface-immobilized Ag NPs
Date of Award2016 Feb 4
Original languageEnglish
SupervisorChangshu Kuo (Supervisor)

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