Establish A Model for Mapping Indication Contraindication and ICD-10-CM/PCS for Drug Utilization Study：Example of Antipsychotic Medications

Abstract

SUMMARY Objective: The objective of this study was to establish a model for mapping indications and contraindications with ICD-10-CM for TFDA approved antipsychotics and evaluate the agreement of our model with reviewing electronic medical records Methods: To establish a model for mapping indication and contraindication with ICD-10-CM the terminology in Chinese drug labels were translated into English with dictionary-based approach Then they were linked to SNOMED CT and further mapped to ICD-10-CM The sensitivity and positive predictive value (PPV) were estimated by reviewing the electronic medical records sampled in National Cheng Kung University Hospital Results: There were 784 pharmaceutical licenses of antipsychotic medications approved by TDFA and the terms were linked to SNOMED CT then matched to ICD-10-CM The mapping rate was 96 5 % Finally the sensitivity and PPV of this model we established were 94 59 % and 80 77 % respectively Conclusion: The mapping model we established had satisfactory sensitivity and PPV; thus this mapping strategy we developed can be applied to other pharmaceutical products and further used could evaluate pharmaceutical reimbursement in Taiwan Keywords: Indication Contraindication ICD-10-CM/PCS SNOMED CT

Date of Award	2020
Original language	English
Supervisor	Yea-Huei Kao (Supervisor)