Fabrication of Nickel Oxide (NiO)-Based Chemical Sensors

Abstract

In recent years novel technologies are developed to make human life longer Related topic about disease prevention and patient's condition monitoring are more concerned by human Among them diabetes and kidney disease are the most of attentive Thus to develop good glucose and urea sensors are very important In previous studies the NiO thin film based-extended gate field effect transistor (EGFET) shows good sensitivity linearity selectivity and small hysteresis width and drift for pH sensing Therefore we used NiO thin film as our sensing membrane to fabricate glucose and urea sensors by immobilizing enzyme First different methods are used to immobilize enzyme Various processes and mechanisms of enzyme immobilization methods are detailedly described Calibration curves are employed to analyze the urea sensing performance In this study the urea sensors are fabricated on glass and polyimide substrates respectively Influences of solute concentration the pH value buffer capacity substrates on the sensing performance device are discussed and demonstrated The reliability and storage stability are investigated as well Then a miniaturized urea sensor is developed to integrate with a microfluidic system which is self-designed The microchannel system is a dynamic sensing environment Experimentally the miniaturized urea sensor shows wide sensing linear region and a long life time in a static measurement However the miniaturized urea sensor shows a high sensitivity and a less interference by other ions Finally glucose sensors are fabricated with two immobilized methods Both of two devices demonstrate excellent glucose sensing performance Therefore the NiO thin film gives the promise for high-performance urea and glucose sensing applications

Date of Award	2015 Feb 11
Original language	English
Supervisor	Wen-Chau Liu (Supervisor)