Prevalence Incidence Comorbidity and Anxiety Risk Factors of Obsessive-Compulsive Disorder in Taiwan

Abstract

Abstract Background Obsessive-compulsive disorder (OCD) is a chronic debilitating anxiety disorder significant in intrusive thoughts and compensation repetitive behaviors Few studies have reported on this condition Asia The relationship among OCD and anxiety disorders remained unknown The first part of specific aim in this study was to estimate the prevalence incidence and psychiatric comorbidities of OCD in Taiwan The second part purpose of this study was to investigate whether specific anxiety disorders correlate with the risks of obsessive-compulsive disorder (OCD) Methods The National Health Insurance Database was used to determine the incidence prevalence and psychiatric comorbidity of OCD by following patients treated for OCD in Taiwan We identified study subjects for 2000-2008 with a principal diagnosis of OCD according to the International Classification of Disease 9th Revision Clinical Modification (ICD-9-CM) diagnostic criteria These patients received either outpatient or inpatient care for their condition We analyzed study subjects by grouping them by age breaking them into seven groups (6-10 11-17 18-24 25-34 35-44 45-64 and >65 years) Rates were directly age- and sex-adjusted to the 2004 Taiwan population distribution We designed a population-based case-control study from the Taiwan National Health Insurance Database which consisted of 2662 patients with newly diagnosis of OCD as cases and 13310 subjects without OCD controls during 2000 to 2011 Age sex demographic variables and covariate psychiatric disorders were compared between OCD cases and control using the chi-square test and t test Anxiety disorders were classified into four groups: Generalized anxiety disorder (GAD) Post-traumatic stress disorder (PTSD) Social phobia and Panic disorder Results The estimated mean annual incidence was 27 57 per 105 inhabitants and the one year prevalence was 65 05 per 105 inhabitants Incidence and prevalence increased with age peaking at age 18-24 years in males and at 35-44 years in females About 57% of adults (>18 years) and 53% of child and adolescent patients (

Date of Award	2014 Feb 14
Original language	English
Supervisor	Sheng-Hsiang Lin (Supervisor)