Study on Glucose Concentration with Scattering Effect Based Upon Stokes-Mueller Polarimetry

  • 林 立恒

Student thesis: Master's Thesis


 A new scheme to measure the glucose concentration with scatters by polarimetry is proposed Diabetics would benefit greatly from a device capable of providing continuous noninvasive monitoring of their blood glucose levels The presence of optical activity object dissolved in an aqueous solution modifies the refractive index of the solution and therefore has an influence on the optical properties Hence a physical correlation may exist between the optical scattering coefficient and concentration of optical activity substance In this study the measuring technique based on the Stokes-Mueller polarimetry to solve the Mueller matrices of a complex sample containing CB and depolarization is developed Output Stokes vectors of four incident polarization states obtained from experiment can be compare to the corresponding value of the simulated Stokes vector the difference is set as error function Appling genetic algorithm the minimum error can be found the circular birefringence and depolarization which relate to the concentrations of glucose and scattering events in turbid media can be extracted too In addition the Monte Carlo simulation can be used to numerically solve the problem of light propagation in turbid media This method relies on repeated random sampling to obtain numerical results The optical properties of interest are obtained from the statistical average of the photon properties It is widely used in biomedical research to analyze propagation of light through the tissue
Date of Award2014 Aug 6
Original languageEnglish
SupervisorYu-Lung Lo (Supervisor)

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