The Application of 3D Electrical Impedance Image to Quantitatively Analyze the Lung Air Distribution

Abstract

Electrical Impedance Tomography (EIT) is a potential technology for real-time or long-term use in continuous monitoring of the lungs This study applies electrical impedance images to quantify and analyze the distribution of air in the lungs There are three parts in this study: (1) Experimental design (2) Measurement calibration and (3) 3D visualization In this study three healthy subjects are recruited with IRB approval and informed consent In the first part five layers of thoracic sections are measured under spontaneous breathing for each subject The impedance images and flows via mouth are both synchronously acquired Then the images are interpolated for three dimension reconstruction and the flow signals are also interpolated for registering to the images In the measurement calibration the flow measurement obtained from spirometer is used as gold standard for calibration using regression method With the correction factors the volume in impedance image may be quantified and compared From the experimental results the error may be smaller than 10 % in 3D measurement and on the contrary greater than 100% in 2D measurement Therefore 2D EIT is not easy to quantify the air distribution of the lung perfusion in the current clinical application 3D EIT has great potential to provide the lung air distribution

Date of Award	2016 Aug 31
Original language	English
Supervisor	Kuo-Sheng Cheng (Supervisor)