YQFC: Yeast Quantitative Feature Comparator

  • 王 來吉

Student thesis: Doctoral Thesis

Abstract

Based on high-throughput omics technologies researchers can easily get two gene lists related to their biological issue Researchers might apply enrichment analysis tools to identify different features between these two gene lists for deeper investigation However most enrichment analysis tools focus on identifying the enriched qualitative features Therefore we developed YQFC (Yeast Quantitative Features Comparator) which can directly compare 85 quantitative features between two yeast gene lists For each quantitative feature YQFC provides three statistical tests to test whether this quantitative feature is significantly different between the two input yeast gene lists Finally we compared the 585 repressed environmental stress response genes with 281 induced environmental stress response genes as case study including comprehensible graphical visualizations and present the results as table view and figure view which allow insight into the functional relationships existing between the identi?ed genes and the detail of quantitative data information By using YQFC webtool may help researchers to know more the difference of quantitative features between the two input yeast gene lists Therefore we believe that YQFC is a useful tool to support the biologists to facilitate the analysis of yeast genes research Now YQFC is available online at: http://cosbi2 ee ncku edu tw/YQFC/
Date of Award2020
Original languageEnglish
SupervisorWei-Sheng Wu (Supervisor)

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