傳染性疾病及訊息研究中心

研究成果 1989 2019

2019
5 引文 (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J-Y. & Liou, J. P., 2019 一月 15, 於 : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

研究成果: Article

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
開啟存取
Colorectal Neoplasms
Neoplasms
Therapeutics
Genome
Mutation
1 引文 (Scopus)

Laminin γ2-enriched extracellular vesicles of oral squamous cell carcinoma cells enhance in vitro lymphangiogenesis via integrin α3-dependent uptake by lymphatic endothelial cells

Wang, S. H., Liou, G. G., Liu, S. H., Chang, J. S., Hsiao, J-R., Yen, Y. C., Chen, Y. L., Wu, W. L., Chang, J-Y. & Chen, Y. W., 2019 六月 1, 於 : International Journal of Cancer. 144, 11, p. 2795-2810 16 p.

研究成果: Article

Lymphangiogenesis
Laminin
Integrins
Squamous Cell Carcinoma
Endothelial Cells

Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca2+ entry

Lin, H. H., Chen, S. J., Shen, M. R., Huang, Y. T., Hsieh, H. P., Lin, S. Y., Lin, C. C., Chang, W. S. W. & Chang, J. Y., 2019 十二月, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 118517.

研究成果: Article

cathepsin S
Cysteine Proteases
Cell Movement
Neoplasms
protease S
1 引文 (Scopus)
開啟存取
Cellular Microenvironment
Cisplatin
Tumors
tumors
Cells

Oral hygiene and the overall survival of head and neck cancer patients

Chang, C. C., Lee, W. T., Hsiao, J. R., Ou, C. Y., Huang, C. C., Tsai, S. T., Chen, K. C., Huang, J. S., Wong, T. Y., Lai, Y. H., Wu, Y. H., Hsueh, W. T., Wu, S. Y., Yen, C. J., Chang, J. Y., Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2019 四月, 於 : Cancer medicine. 8, 4, p. 1854-1864 11 p.

研究成果: Article

開啟存取
Oral Hygiene
Head and Neck Neoplasms
Survival
Confidence Intervals
Tooth
1 引文 (Scopus)
Neoadjuvant Therapy
Squamous Cell Carcinoma
Clinical Trials
Staining and Labeling
Neoplasms
Head and Neck Neoplasms
Alcohol Drinking
Ethanol
Survival
Genes

TNF-α-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility

Hsing, E. W., Shiah, S. G., Peng, H. Y., Chen, Y. W., Chuu, C. P., Hsiao, J. R., Lyu, P. C. & Chang, J. Y., 2019 三月, 於 : PloS one. 14, 3, e0213463.

研究成果: Article

開啟存取
squamous cell carcinoma
tumor necrosis factor-alpha
Cell Movement
Squamous Cell Carcinoma
mouth
Head and Neck Neoplasms
Alcohols
Surveys and Questionnaires
Alleles
Validation Studies
2018
1 引文 (Scopus)
Cell Polarity
Cell Movement
Tubulin
Pseudopodia
Acetylation

Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J-Y., Liou, J. P. & Lee, H. Y., 2018 一月 1, 於 : Organic and Biomolecular Chemistry. 16, 25, 1 p.

研究成果: Comment/debate

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Emotions
1 引文 (Scopus)
Fresh Water
Taiwan
shrimp
Parasites
Nucleic Acid Databases
1 引文 (Scopus)
Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines
2 引文 (Scopus)
Hypoxia-Inducible Factor 1
Phosphorylation
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Microtubules
6 引文 (Scopus)
Microbiota
Genetic Polymorphisms
Life Style
Squamous Cell Carcinoma
Oral Hygiene
Ubiquitin-Conjugating Enzymes
Carmustine
Ubiquitination
Methyltransferases
Cells
2017
3 引文 (Scopus)
Fanconi Anemia
Recombinational DNA Repair
Cisplatin
Fanconi Anemia Complementation Group D2 Protein
Genes
4 引文 (Scopus)

Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells

Chen, H. H., Chang, H. H., Chang, J-Y., Tang, Y. C., Cheng, Y. C., Lin, L. M., Cheng, S. Y., Huang, C. H., Sun, M. W., Chen, C. T. & Kuo, C. C., 2017 十二月 1, 於 : Free Radical Biology and Medicine. 113, p. 505-518 14 p.

研究成果: Article

KB Cells
Acetylation
Type II DNA Topoisomerase
Poisons
Transcription
1 引文 (Scopus)
Fibronectins
Matrix Metalloproteinases
Up-Regulation
Neoplasm Metastasis
Epidermal Growth Factor
22 引文 (Scopus)

Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness

Hou, P. C., Li, Y. H., Lin, S. C., Lin, S. C., Lee, J. C., Lin, B. W., Liou, J. P., Chang, J. Y., Kuo, C. C., Liu, Y. M., Sun, H. S. & Tsai, S. J., 2017 八月 15, 於 : Cancer Research. 77, 16, p. 4305-4316 12 p.

研究成果: Article

Dual-Specificity Phosphatases
Dual Specificity Phosphatase 2
Colonic Neoplasms
Down-Regulation
Neoplasms
12 引文 (Scopus)
Head and Neck Neoplasms
Taiwan
Alcohols
Hypopharyngeal Neoplasms
Oropharyngeal Neoplasms
5 引文 (Scopus)

Investigating the association between diet and risk of head and neck cancer in Taiwan

Chang, C. C., Lee, W. T., Lee, Y. C., Huang, C. C., Ou, C. Y., Lin, Y. H., Huang, J. S., Wong, T. Y., Chen, K. C., Hsiao, J. R., Lu, Y. C., Tsai, S. T., Lai, Y. H., Wu, Y. H., Hsueh, W. T., Yen, C. J., Wu, S. Y., Chang, J. Y., Fang, S. Y., Wu, J. L. 及其他5, Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 一月 1, 於 : Oncotarget. 8, 58, p. 98865-98875 11 p.

研究成果: Article

Head and Neck Neoplasms
Taiwan
Vegetables
Diet
Fruit
6 引文 (Scopus)
Minoxidil
Neuroprotective Agents
Peripheral Nervous System Diseases
Paclitaxel
Hair
7 引文 (Scopus)

Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 Regulation

Chang, W. M., Lin, Y. F., Su, C. Y., Peng, H. Y., Chang, Y. C., Hsiao, J. R., Chen, C. L., Chang, J. Y., Shieh, Y. S., Hsiao, M. & Shiah, S. G., 2017 一月 25, 於 : Scientific reports. 7, 41131.

研究成果: Article

Head and Neck Neoplasms
Parathyroid Hormone
Hormones
Growth
Calcium
6 引文 (Scopus)
Acanthamoeba castellanii
Acanthamoeba
Cytophagocytosis
Aminopeptidases
proteins

Pharmacokinetics and protein binding of MPT0B292

Tien, Y. E., Li, C. J., Liou, J. P., Chang, J-Y. & Huang, J. D., 2017 七月 1, 於 : Biopharmaceutics and Drug Disposition. 38, 5, p. 340-350 11 p.

研究成果: Article

Protein Binding
Pharmacokinetics
Albumins
Pharmaceutical Preparations
Nanoparticles

Regular recreational physical activity and risk of head and neck cancer

Lin, C. L., Lee, W. T., Ou, C. Y., Hsiao, J. R., Huang, C. C., Huang, J. S., Wong, T. Y., Chen, K. C., Tsai, S. T., Fang, S. Y., Huang, T. T., Wu, J. L., Wu, Y. H., Hsueh, W. T., Yen, C. J., Lai, Y. H., Liao, H. C., Wu, S. Y., Yang, M. W., Lin, F. C. 及其他6, Chang, J. Y., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 四月 21, 於 : BMC cancer. 17, 1, 286.

研究成果: Article

Head and Neck Neoplasms
Tobacco Products
Vegetables
Fruit
Logistic Models

Skin Delivery of Clec4a Small Hairpin RNA Elicited an Effective Antitumor Response by Enhancing CD8+ Immunity In Vivo

Weng, T. Y., Li, C. J., Li, C. Y., Hung, Y. H., Yen, M. C., Chang, Y. W., Chen, Y. H., Chen, Y. L., Hsu, H. P., Chang, J. Y. & Lai, M. D., 2017 十二月, 於 : Molecular Therapy - Nucleic Acids. 9, p. 419-427 9 p.

研究成果: Article

Small Interfering RNA
Immunity
Skin
Neoplasms
DNA Vaccines
5 引文 (Scopus)
Macrophage Colony-Stimulating Factor
Colony-Stimulating Factor Receptors
Immunity
Macrophages
Genes
25 引文 (Scopus)

Tumour cell-derived WNT5B modulates in vitro lymphangiogenesis via induction of partial endothelial-mesenchymal transition of lymphatic endothelial cells

Wang, S. H., Chang, J. S., Hsiao, J. R., Yen, Y. C., Jiang, S. S., Liu, S. H., Chen, Y. L., Shen, Y. Y., Chang, J. Y. & Chen, Y. W., 2017 三月 1, 於 : Oncogene. 36, 11, p. 1503-1515 13 p.

研究成果: Article

Lymphangiogenesis
Squamous Cell Carcinoma
Endothelial Cells
Neoplasm Metastasis
Lymph Nodes
8 引文 (Scopus)

Whether CD44 is an applicable marker for glioma stem cells

Wang, H. H., Liao, C. C., Chow, N. H., Huang, L. L. H., Chuang, J. I., Wei, K. C. & Shin, J. W., 2017 一月 1, 於 : American Journal of Translational Research. 9, 11, p. 4785-4806 22 p., AJTR0052194.

研究成果: Article

Stem cells
Glioma
Stem Cells
Hyaluronic Acid
Neoplastic Stem Cells
2016
6 引文 (Scopus)

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J-Y., Liou, J. P. & Lee, H. Y., 2016 一月 1, 於 : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

研究成果: Article

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Inhibitory Concentration 50
8 引文 (Scopus)
betel
Tobacco
Head and Neck Neoplasms
Mastication
tobacco
2 引文 (Scopus)

Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer

Liao, H. C., Wu, S-Y., Ou, C-Y., Hsiao, J-R., Huang, J-S., Tsai, S-T., Huang, C-C., Wang, D-Y., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Huang, T-T., Wu, Y-H., Hsueh, W-T., Yen, C-J., Yang, M-W., Lin, F-C., Lai, Y-H., Chang, J-Y. 及其他6, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 九月 1, 於 : Cancer Causes and Control. 27, 9, p. 1105-1115 11 p.

研究成果: Article

Head and Neck Neoplasms
Immunoglobulin E
Hypersensitivity
Serum
Odds Ratio
4 引文 (Scopus)

A phase i clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment John T Kung

Liu, K. J., Chao, T. Y., Chang, J. Y., Cheng, A. L., Ch'Ang, H. J., Kao, W. Y., Wu, Y. C., Yu, W. L., Chung, T. R. & Whang-Peng, J., 2016 八月 24, 於 : Journal of biomedical science. 23, 1, 64.

研究成果: Article

Tetanus Toxoid
Carcinoembryonic Antigen
Immunotherapy
Dendritic Cells
Interleukin-2
8 引文 (Scopus)
cathepsin S
Protein-Tyrosine Kinases
Endosomes
Epidermal Growth Factor
STAT3 Transcription Factor
4 引文 (Scopus)
oxaliplatin
Transferrin Receptors
Deferoxamine
Platinum
Uterine Cervical Neoplasms
8 引文 (Scopus)
irinotecan
gemcitabine
Leucovorin
Pancreatic Neoplasms
Fluorouracil
16 引文 (Scopus)

Dysregulation of RUNX2/activin-A axis upon miR-376c downregulation promotes lymph node metastasis in head and neck squamous cell carcinoma

Chang, W. M., Lin, Y. F., Su, C. Y., Peng, H. Y., Chang, Y. C., Lai, T. C., Wu, G. H., Hsu, Y. M., Chi, L. H., Hsiao, J. R., Chen, C. L., Chang, J. Y., Shieh, Y. S., Hsiao, M. & Shiah, S. G., 2016 十二月 15, 於 : Cancer Research. 76, 24, p. 7140-7150 11 p.

研究成果: Article

Down-Regulation
Lymph Nodes
Neoplasm Metastasis
3' Untranslated Regions
Head and Neck Neoplasms
Insulin-Like Growth Factor Binding Protein 3
Somatomedins
Integrins
Cell Movement
Squamous Cell Carcinoma
Blastocystis
HT29 Cells
Retinoic Acid Receptors
retinoic acid
Tretinoin
20 引文 (Scopus)

IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma

Peng, H. Y., Jiang, S. S., Hsiao, J. R., Hsiao, M., Hsu, Y. M., Wu, G. H., Chang, W. M., Chang, J. Y., Jin, S. L. C. & Shiah, S. G., 2016 六月 1, 於 : Molecular Oncology. 10, 6, p. 895-909 15 p.

研究成果: Article

Interleukin-8
Squamous Cell Carcinoma
Suppressor of Cytokine Signaling Proteins
Cell Movement
Janus Kinases
7 引文 (Scopus)

Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma

Cheng, C. W., Hsiao, J. R., Fan, C. C., Lo, Y. K., Tzen, C. Y., Wu, L. W., Fang, W. Y., Cheng, A. J., Chen, C. H., Chang, I. S., Jiang, S. S., Chang, J. Y. & Lee, A. Y. L., 2016 五月 1, 於 : Molecular Carcinogenesis. 55, 5, p. 499-513 15 p.

研究成果: Article

Growth Differentiation Factor 10
Epithelial-Mesenchymal Transition
Squamous Cell Carcinoma
Drug Therapy
Transforming Growth Factors
17 引文 (Scopus)

MiR-520h is crucial for DAPK2 regulation and breast cancer progression

Su, C. M., Wang, M. Y., Hong, C. C., Chen, H. A., Su, Y. H., Wu, C. H., Huang, M. T., Chang, Y. W., Jiang, S. S., Sung, S. Y., Chang, J. Y., Chen, L. T., Chen, P. S. & Su, J. L., 2016 三月 3, 於 : Oncogene. 35, 9, p. 1134-1142 9 p.

研究成果: Article

Death-Associated Protein Kinases
MicroRNAs
Breast Neoplasms
Drug Resistance
3' Untranslated Regions
12 引文 (Scopus)

MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma

Peng, H. Y., Cheng, Y. C., Hsu, Y. M., Wu, G. H., Kuo, C. C., Liou, J. P., Chang, J. Y., Jin, S. L. C. & Shiah, S. G., 2016 七月, 於 : PloS one. 11, 7, e0158440.

研究成果: Article

non-specific protein-tyrosine kinase
Janus Kinase 2
STAT3 Transcription Factor
squamous cell carcinoma
Microtubules
23 引文 (Scopus)

The Role of Wnt Signaling in Squamous Cell Carcinoma

Shiah, S. G., Shieh, Y. S. & Chang, J. Y., 2016 二月 1, 於 : Journal of Dental Research. 95, 2, p. 129-134 6 p.

研究成果: Review article

Wnt Signaling Pathway
Squamous Cell Carcinoma
MicroRNAs
Catenins
Neoplasms
36 引文 (Scopus)
Ubiquitin-Conjugating Enzymes
Mouth Neoplasms
Transforming Growth Factors
Up-Regulation
Epithelial Cells
2015
25 引文 (Scopus)

Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cells

Chen, C. C., Lee, K. D., Pai, M. Y., Chu, P. Y., Hsu, C. C., Chiu, C. C., Chen, L. T., Chang, J-Y., Hsiao, S. H. & Leu, Y. W., 2015 十月 13, 於 : Cancer Cell International. 15, 1, 98.

研究成果: Article

DNA Methylation
Drug Resistance
Uterine Cervical Neoplasms
Methylation
oxaliplatin
9 引文 (Scopus)
Neuroprotective Agents
Paclitaxel
Ligands
Neurons
Drug Therapy