傳染性疾病及訊息研究中心

研究成果

1989

Direct comparisons of peripheral T-cell lymphoma with diffuse B-cell lymphoma of comparable histological grades - Should peripheral T-cell lymphoma be considered separately?

Cheng, A. L., Chen, Y. C., Wang, C. H., Su, I. J., Hsieh, H. C., Chang, J. Y., Hwang, W. S., Su, W. C., Liu, T. W., Tien, H. F., Tsai, W., Shen, M. C. & Liu, C. H., 1989 一月 1, 於 : Journal of Clinical Oncology. 7, 6, p. 725-731 7 p.

研究成果: Article

66 引文 斯高帕斯(Scopus)
1990

Antitumor Agents. 111.† New 4-Hydroxylated and 4-Halogenated Anilino Derivatives of 4'-Demethylepipodophyllotoxin as Potent Inhibitors of Human DNA Topoisomerase II

Lee, K. H., Beers, S. A., Mori, M., Wang, Z. Q., Kuo, Y. H., Li, L., Liu, S. Y., Chang, J-Y., Han, F. S. & Cheng, Y. C., 1990 一月 1, 於 : Journal of Medicinal Chemistry. 33, 5, p. 1364-1368 5 p.

研究成果: Article

106 引文 斯高帕斯(Scopus)

Antitumor Agents. 113. New 4β-Arylamino Derivatives of 4-O-Demethylepipodophyllotoxin and Related Compounds as Potent Inhibitors of Human DNA Topoisomerase II

Wang, Z. Q., Kuo, Y. H., Schnur, D., Bowen, J. P., Liu, S. Y., Han, F. S., Chang, J. Y., Cheng, Y. C. & Lee, K. H., 1990 一月 1, 於 : Journal of Medicinal Chemistry. 33, 9, p. 2660-2666 7 p.

研究成果: Article

120 引文 斯高帕斯(Scopus)
1991
67 引文 斯高帕斯(Scopus)

Effect of 4β-Arylamino Derivatives of 4′-O-Demethylepipodophyllotoxin on Human DNA Topoisomerase II, Tubulin Polymerization, KB Cells, and Their Resistant Variants

Chang, J. Y., Han, F. S., Liu, S. Y., Wang, Z. Q., Lee, K. H. & Cheng, Y. C., 1991 四月 1, 於 : Cancer Research. 51, 7, p. 1755-1759 5 p.

研究成果: Article

46 引文 斯高帕斯(Scopus)

Menadione-induced DNA damage in a human tumor cell line

Ngo, E. O., Sun, T. P., Chang, J. Y., Wang, C. C., Chi, K. H., Cheng, A. L. & Nutter, L. M., 1991 十月 24, 於 : Biochemical Pharmacology. 42, 10, p. 1961-1968 8 p.

研究成果: Article

61 引文 斯高帕斯(Scopus)
1992

Characterization of camptothecin-resistant chinese hamster lung cells

Chang, J. Y., Dethlefsen, L. A., Barley, L. R., Zhou, B. S. & Cheng, Y. C., 1992 六月 9, 於 : Biochemical Pharmacology. 43, 11, p. 2443-2452 10 p.

研究成果: Article

76 引文 斯高帕斯(Scopus)
1993
13 引文 斯高帕斯(Scopus)

Erratum: Characterization of camptothecin-resistant Chinese hamster lung cells (Biochemical Pharmacology Vol. 43 (1992) 2443-2452)

Chang, J. Y., Dethlefsen, L. A., Barley, L. R., Zhou, B. S. & Cheng, Y. C., 1993 一月 1, 於 : Biochemical Pharmacology. 45, 3, 1 p.

研究成果: Comment/debate

1995

Combination chemoimmunotherapy with interferon-alpha and cisplatin in patients with advanced non-small cell lung cancer

Chao, T. Y., Hwang, W. S., Yang, M. J., Chang, J. Y., Wang, C. C., Hseuh, E. J., Huang, S. H. & Chen, W. C., 1995 一月 1, 於 : Chinese Medical Journal (Taipei). 56, 4, p. 232-238 7 p.

研究成果: Article

4 引文 斯高帕斯(Scopus)
4 引文 斯高帕斯(Scopus)

Differential expression of the human metastasis adhesion molecule CD44V in normal and carcinomatous stomach mucosa of chinese subjects

Harn, HJ. J., Ho, LI. I., Chang, JY. Y., Wu, CW. W., Jiang, SY. Y., Lee, HS. S. & Lee, WH. H., 1995 三月 1, 於 : Cancer. 75, 5, p. 1065-1071 7 p.

研究成果: Article

49 引文 斯高帕斯(Scopus)

Effects of indomethacin on lymphokine-activated killer cell activities in cancer patients

Chao, T. Y., Ting, C. S., Yeh, M. Y., Chang, J. Y., Wang, C. C. & Chu, T. M., 1995 一月 1, 於 : Tumor Biology. 16, 4, p. 230-242 13 p.

研究成果: Article

15 引文 斯高帕斯(Scopus)

Epstein-Barr virus-associated gastric adenocarcinoma in Taiwan

Harn, H. J., Chang, J. Y., Wang, M. W., Ho, L. I., Lee, H. S., Chiang, J. H. & Lee, W. H., 1995 三月, 於 : Human Pathology. 26, 3, p. 267-271 5 p.

研究成果: Article

89 引文 斯高帕斯(Scopus)

Primary non-Hodgkin's lymphoma of the mediastinum: A clinicopathological report of six cases

Juan, M. T., Sheu, L. F., Chang, J-Y. & Hwang, W. S., 1995 一月 1, 於 : Chinese Medical Journal (Taipei). 55, 4, p. 325-330 6 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)
1996

Allogeneic bone marrow transplantation for fourteen patients with severe aplastic anemia

Hsueh, E. J., Hwang, W. S., Huang, S. H., Chao, T. Y., Chang, J-Y. & Wang, C. C., 1996 四月 1, 於 : Chinese Medical Journal (Taipei). 57, 4, p. 247-253 7 p.

研究成果: Article

51 引文 斯高帕斯(Scopus)

Down regulation of bcl-2 by p53 in nasopharyngeal carcinoma and lack of detection of its specific t(14;18) chromosomal translocation in fixed tissues

Harn, H. J., Ho, L. I., Liu, C. A., Liu, G. C., Lin, F. G., Lin, J. J., Chang, J. Y. & Lee, W. H., 1996 一月 1, 於 : Histopathology. 28, 4, p. 317-323 7 p.

研究成果: Article

42 引文 斯高帕斯(Scopus)

Examination of pericardial effusions by cytology and immunocytochemistry.

Chen, L. M., Chao, T. Y., Chiang, J. H., Nieh, S., Chang, J-Y., Hwang, S. H., Hseuh, E. J. & Wang, C. C., 1996 一月 1, 於 : Zhonghua yi xue za zhi = Chinese medical journal; Free China ed. 58, 4, p. 248-253 6 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)

Expression of Epstein-Barr virus-encoded RNAs as a marker for metastatic undifferentiated nasopharyngeal carcinoma

Chao, T. Y., Chow, K. C., Chang, J-Y., Wang, C. C., Tsao, T. Y., Harn, H. J. & Chi, K. H., 1996 七月 1, 於 : Cancer. 78, 1, p. 24-29 6 p.

研究成果: Article

28 引文 斯高帕斯(Scopus)

Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain

Yang, C. Y., Wong, C. S., Chang, J. Y. & Ho, S. T., 1996 四月, 於 : Canadian Journal of Anaesthesia. 43, 4, p. 379-383 5 p.

研究成果: Article

165 引文 斯高帕斯(Scopus)
1998

Acquired hemophilia A: Report of two cases

Chen, Y. C., Chang, J. Y., Hsueh, E. J., Wan, H. L. & Chao, T. Y., 1998 九月 1, 於 : Chinese Medical Journal (Taipei). 61, 9, p. 538-544 7 p.

研究成果: Article

2 引文 斯高帕斯(Scopus)
2000

Unique biochemical, cytotoxic, and antitumor activity of camptothecin and 4β-amino-4'-O-demethylepipodophyllotoxin conjugates

Chang, J-Y., Guo, X., Chen, H. X., Jiang, Z., Fu, Q., Wang, H. K., Bastow, K. F., Zhu, X. K., Guan, J., Lee, K. H. & Cheng, Y. C., 2000 三月 1, 於 : Biochemical Pharmacology. 59, 5, p. 497-508 12 p.

研究成果: Article

30 引文 斯高帕斯(Scopus)
2001

Immunohistochemical studies of Na + /I - symporter in human thyroid tissues - A correlation with clinical thyroid scintigraphy

Lee, C. H., Yang, A. H., Chang, J-Y., Huang, C. L. & Chi, C. W., 2001 七月 12, 於 : Chinese Medical Journal (Taipei). 64, 3, p. 141-146 6 p.

研究成果: Article

The p38 mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumor necrosis factor in osteoblasts

Chae, H. J., Chae, S. W., Chin, H. Y., Bang, B. G., Cho, S. B., Han, K. S., Kim, S. C., Tae, K. C., Lee, K. H., Kim, D. E., Im, M. K., Lee, S. J., Chang, J. Y., Lee, Y. M., Kim, H. M., Kim, H. H., Lee, Z. H. & Kim, H. R., 2001 二月 13, 於 : Bone. 28, 1, p. 45-53 9 p.

研究成果: Article

35 引文 斯高帕斯(Scopus)
2002

2,2′-Diphenyl-1-picrylhydrazyl radical-scavenging active components from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) hulls

Kuo, C. C., Chiang, W., Liu, G. P., Chien, Y. L., Chang, J-Y., Lee, C. K., Lo, J. M., Huang, S. L., Shih, M. C. & Kuo, Y. H., 2002 十月 9, 於 : Journal of Agricultural and Food Chemistry. 50, 21, p. 5850-5855 6 p.

研究成果: Article

68 引文 斯高帕斯(Scopus)

Antitumor AHMA linked to DNA minor groove binding agents: Synthesis and biological evaluation

Rastogi, K., Chang, J. Y., Pan, W. Y., Chen, C. H., Chou, T. C., Chen, L. T. & Su, T. L., 2002 九月 26, 於 : Journal of Medicinal Chemistry. 45, 20, p. 4485-4493 9 p.

研究成果: Article

30 引文 斯高帕斯(Scopus)

A phase I study of weekly docetaxel, 24-hour infusion of high-dose fluorouracil/leucovorin and cisplatin in patients with advanced gastric cancer

Chen, L. T., Liu, T. W., Wu, C. W., Chung, T. R., Shiah, H. S., Jan, C. M., Ming Liu, J., Whang-Peng, J. & Chang, J-Y., 2002 十二月 1, 於 : Oncology. 63, 3, p. 239-247 9 p.

研究成果: Article

17 引文 斯高帕斯(Scopus)
5 引文 斯高帕斯(Scopus)

Novel mutation of topoisomerase I in rendering cells resistant to camptothecin

Chang, J. Y., Liu, J. F., Juang, S. H., Liu, T. W. & Chen, L. T., 2002 七月 1, 於 : Cancer Research. 62, 13, p. 3716-3721 6 p.

研究成果: Article

49 引文 斯高帕斯(Scopus)

Phase II and pharmacokinetic study of GL331 in previously treated Chinese gastric cancer patients

Liu, J., Chen, L., Chao, Y., Li, A., Wu, C., Liu, T. S., Shiah, H., Chang, J., Chen, J., Wu, H., Lin, W., Lan, C. & Whang-Peng, J., 2002 五月 6, 於 : Cancer Chemotherapy and Pharmacology. 49, 5, p. 425-428 4 p.

研究成果: Article

12 引文 斯高帕斯(Scopus)
2003

Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent

Chang, J-Y., Hsieh, H. P., Pan, W. Y., Liou, J. P., Bey, S. J., Chen, L. T., Liu, J. F. & Song, J. S., 2003 六月 15, 於 : Biochemical Pharmacology. 65, 12, p. 2009-2019 11 p.

研究成果: Article

20 引文 斯高帕斯(Scopus)

Erratum: Structure-activity and crystallographic analysis of benzophenone derivatives - The potential anticancer agents (Bioorganic and Medicinal Chemistry Letters (2003) 13 (101) PII S0960894X02008508)

Hsieh, H. P., Liou, J. P., Lin, Y. T., Mahindroo, N., Chang, J. Y., Yang, Y. N., Chern, S. S., Tan, U. K., Chang, C. W., Chen, T. W., Lin, C. H., Chang, Y. Y. & Wang, C. C., 2003 三月 10, 於 : Bioorganic and Medicinal Chemistry Letters. 13, 5, 1 p.

研究成果: Comment/debate

New analogues of AHMA as potential antitumor agents: Synthesis and biological activity

Chang, J. Y., Lin, C. F., Pan, W. Y., Bacherikov, V., Chou, T. C., Chen, C. H., Dong, H., Cheng, S. Y., Tasi, T. J., Lin, Y. W., Chen, K. T., Chen, L. T. & Su, T. L., 2003 十一月 17, 於 : Bioorganic and Medicinal Chemistry. 11, 23, p. 4959-4969 11 p.

研究成果: Article

25 引文 斯高帕斯(Scopus)

Structure-activity and crystallographic analysis of benzophenone derivatives - The potential anticancer agents

Hsieh, H. P., Liou, J. P., Lin, Y. T., Mahindroo, N., Chang, J. Y., Yang, Y. N., Chern, S. S., Tan, U. K., Chang, C. W., Chen, T. W., Lin, C. H., Chang, Y. Y. & Wang, C. C., 2003 一月 6, 於 : Bioorganic and Medicinal Chemistry Letters. 13, 1, p. 101-105 5 p.

研究成果: Article

72 引文 斯高帕斯(Scopus)
2004

A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells

Juang, S. H., Pan, W. Y., Kuo, C. C., Liou, J. P., Hung, Y. M., Chen, L. T., Hsieh, H. P. & Chang, J-Y., 2004 七月 15, 於 : Biochemical Pharmacology. 68, 2, p. 293-303 11 p.

研究成果: Article

17 引文 斯高帕斯(Scopus)

BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo

Kuo, C. C., Hsieh, H. P., Pan, W. Y., Chen, C. P., Liou, J. P., Lee, S. J., Chang, Y. L., Chen, L. T., Chen, C. T. & Chang, J. Y., 2004 七月 1, 於 : Cancer Research. 64, 13, p. 4621-4628 8 p.

研究成果: Article

181 引文 斯高帕斯(Scopus)

Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents

Liou, J. P., Chang, Y. L., Kuo, F. M., Chang, C. W., Tseng, H. Y., Wang, C. C., Yang, Y. N., Chang, J. Y., Lee, S. J. & Hsieh, H. P., 2004 八月 12, 於 : Journal of Medicinal Chemistry. 47, 17, p. 4247-4257 11 p.

研究成果: Article

163 引文 斯高帕斯(Scopus)

Hepatocellular carcinoma with intra-atrial tumor thrombi: A report of three cases responsive to thalidomide treatment and literature review

Chang, J. Y., Ka, W. S., Chao, T. Y., Liu, T. W., Chuang, T. R. & Chen, L. T., 2004 一月 1, 於 : Oncology. 67, 3-4, p. 320-326 7 p.

研究成果: Article

53 引文 斯高帕斯(Scopus)

Phase II study of weekly oxaliplatin and 24-h infusion of high-dose 5-fluorouracil and folinic acid in the treatment of advanced gastric cancer

Chao, Y., Yeh, K. H., Chang, C. J., Chen, L. T., Chao, T. Y., Wu, M. F., Chang, C. S., Chang, J. Y., Chung, C. Y., Kao, W. Y., Hsieh, R. K. & Cheng, A. L., 2004 八月 2, 於 : British Journal of Cancer. 91, 3, p. 453-458 6 p.

研究成果: Article

70 引文 斯高帕斯(Scopus)
83 引文 斯高帕斯(Scopus)

Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents

Liou, J. P., Chang, J. Y., Chang, C. W., Chang, C. Y., Mahindroo, N., Kuo, F. M. & Hsieh, H. P., 2004 五月 20, 於 : Journal of Medicinal Chemistry. 47, 11, p. 2897-2905 9 p.

研究成果: Article

99 引文 斯高帕斯(Scopus)
57 引文 斯高帕斯(Scopus)
2005

Cytotoxic triterpenes from the aerial roots of Ficus microcarpa

Chiang, Y. M., Chang, J-Y., Kuo, C. C., Chang, C. Y. & Kuo, Y. H., 2005 一月 1, 於 : Phytochemistry. 66, 4, p. 495-501 7 p.

研究成果: Article

109 引文 斯高帕斯(Scopus)

Four new 6-nor-5(6→7)abeo-abietane type diterpenes and antitumoral cytotoxic diterpene constituents from the bark of Taiwania cryptomerioides

Chang, C. I., Chang, J. Y., Kuo, C. C., Pan, W. Y. & Kuo, Y. H., 2005 一月 1, 於 : Planta Medica. 71, 1, p. 72-76 5 p.

研究成果: Article

69 引文 斯高帕斯(Scopus)

Hepatocellular carcinoma associated with acquired von Willebrand disease and extreme thrombocytosis [2]

Chen, C. C., Chang, J. Y., Liu, K. J., Chan, C., Ho, C. H., Lee, S. C. & Chen, L. T., 2005 六月 1, 於 : Annals of Oncology. 16, 6, p. 988-989 2 p.

研究成果: Letter

6 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

Pulmonary embolism after transcatheter arterial chemoembolization

Shiah, H. S., Liu, T. W., Chen, L. T., Chang, J-Y., Liu, J. M., Chuang, T. R., Lee, W. S. & Whang-Peng, J., 2005 十二月 1, 於 : European Journal of Cancer Care. 14, 5, p. 440-442 3 p.

研究成果: Article

11 引文 斯高帕斯(Scopus)

Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives

Bacherikov, V. A., Chang, J. Y., Lin, Y. W., Chen, C. H., Pan, W. Y., Dong, H., Lee, R. Z., Chou, T. C. & Su, T. L., 2005 十二月 1, 於 : Bioorganic and Medicinal Chemistry. 13, 23, p. 6513-6520 8 p.

研究成果: Article

26 引文 斯高帕斯(Scopus)

α-fetoprotein response predicts survival benefits of thalidomide in advanced hepatocellular carcinoma

Chen, L. T., Liu, T. W., Chao, Y., Shiah, H. S., Chang, J-Y., Juang, S. H., Chen, S. C., Chuang, T. R., Chin, Y. H. & Whang-Peng, J., 2005 八月 1, 於 : Alimentary Pharmacology and Therapeutics. 22, 3, p. 217-226 10 p.

研究成果: Article

31 引文 斯高帕斯(Scopus)