生物化學暨分子生物學研究所

研究成果

2020

Targeting vascular smooth muscle cell dysfunction with xanthine derivative KMUP-3 inhibits abdominal aortic aneurysm in mice

Lai, C. H., Chang, C. W., Lee, F. T., Kuo, C. H., Hsu, J. H., Liu, C. P., Wu, H. L. & Yeh, J. L., 2020 三月, 於 : Atherosclerosis. 297, p. 16-24 9 p.

研究成果: Article

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2019
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1 引文 斯高帕斯(Scopus)

A novel αiIbβ3 antagonist from snake venom prevents thrombosis without causing bleeding

Kuo, Y. J., Chung, C. H., Pan, T. Y., Chuang, W. J. & Huang, T. F., 2019 十二月 21, 於 : Toxins. 12, 1, 11.

研究成果: Article

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Blocking IL-19 signaling ameliorates allergen-induced airway inflammation

Weng, Y. H., Chen, W. Y., Lin, Y. L., Wang, J. Y. & Chang, M. S., 2019 一月 1, 於 : Frontiers in Immunology. 10, APR, 968.

研究成果: Article

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1 引文 斯高帕斯(Scopus)

Cancer immunotherapy: Silencing intracellular negative immune regulators of dendritic cells

Liu, Y. H., Yeh, I. J., Lai, M. D., Liu, K. T., Kuo, P. L. & Yen, M. C., 2019 一月 1, 於 : Cancers. 11, 1, 108.

研究成果: Review article

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2 引文 斯高帕斯(Scopus)

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons

Yang, Q., Yu, C. H., Zhao, F., Dang, Y., Wu, C., Xie, P., Sachs, M. S. & Liu, Y., 2019 九月 26, 於 : Nucleic acids research. 47, 17, p. 9243-9258 16 p.

研究成果: Article

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Erratum: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy (Oncotarget (2015) 6 (13671–13687) DOI: 10.18632/oncotarget.3701)

Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., 2019 一月 1, 於 : Oncotarget. 10, 60, p. 6536-6537 2 p.

研究成果: Comment/debate

Expression of prothymosin α in lung cancer is associated with squamous cell carcinoma and smoking

Kuo, Y. H., Shiau, A. L., Tung, C. L., Su, Y. C., Li, C. F., Su, B. H., Tsao, C. J., Wu, C. L., Feng, Y. H. & Wu, P., 2019 六月, 於 : Oncology Letters. 17, 6, p. 5740-5746 7 p.

研究成果: Article

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1 引文 斯高帕斯(Scopus)

Inhibition of cd44 induces apoptosis, inflammation, and matrix metalloproteinase expression in tendinopathy

Wu, P. T., Su, W. R., Li, C. L., Hsieh, J. L., Ma, C. H., Wu, C. L., Kuo, L. C., Jou, I. M. & Chen, S. Y., 2019 一月 1, 於 : Journal of Biological Chemistry. 294, 52, p. 20177-20184 8 p.

研究成果: Article

Nasogastric tube dislodgment detection in rehabilitation patients based on fog computing with warning sensors and fuzzy petri net

Li, C. M., Ho, Y-R., Chen, W. L., Lin, C. H., Chen, M. Y. & Chen, Y. Z., 2019 一月 1, 於 : Sensors and Materials. 31, 1, p. 117-130 14 p.

研究成果: Article

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2 引文 斯高帕斯(Scopus)

Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Feng, Y. H., Su, Y. C., Lin, S. F., Lin, P. R., Wu, C. L., Tung, C. L., Li, C. F., Shieh, G. S. & Shiau, A. L., 2019 八月 9, 於 : BMC cancer. 19, 1, 791.

研究成果: Article

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Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8

Wang, H. C., Lin, Y. L., Hsu, C. C., Chao, Y. J., Hou, Y. C., Chiu, T. J., Huang, P. H., Tang, M. J., Chen, L. T. & Shan, Y. S., 2019 一月 1, 於 : Theranostics. 9, 24, p. 7168-7183 16 p.

研究成果: Article

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1 引文 斯高帕斯(Scopus)
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Prothymosin α promotes STAT3 acetylation to induce cystogenesis in Pkd1-deficient mice

Chen, Y. C., Su, Y. C., Shieh, G. S., Su, B. H., Su, W. C., Huang, P. H., Jiang, S. T., Shiau, A. L. & Wu, C. L., 2019 十一月 1, 於 : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 11, p. 13051-13061 11 p.

研究成果: Article

6 引文 斯高帕斯(Scopus)
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The role of vascular smooth muscle cell membrane-bound thrombomodulin in neointima formation

Wang, K. C., Chen, P. S., Chao, T. H., Luo, C. Y., Chung, H. C., Tseng, S. Y., Huang, T. Y., Lin, Y. L., Shi, G. Y., Wu, H. L. & Li, Y. H., 2019 八月, 於 : Atherosclerosis. 287, p. 54-63 10 p.

研究成果: Article

Tumor Endothelial Marker 1 (TEM1/Endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors

Hong, Y. K., Lee, Y. C., Cheng, T. L., Lai, C. H., Hsu, C. K., Kuo, C. H., Hsu, Y. Y., Li, J. T., Chang, B. I., Ma, C. Y., Lin, S. W., Wang, K. C., Shi, G. Y. & Wu, H. L., 2019 十月, 於 : Journal of Investigative Dermatology. 139, 10, p. 2204-2214.e7

研究成果: Article

2018

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli

Kuo, C. J., Wang, S. T., Lin, C. M., Chiu, H. C., Huang, C. R., Lee, D. Y., Chang, G. D., Chou, T. C., Chen, J. W. & Chen, C. S., 2018 三月 1, 於 : Cell Death and Disease. 9, 3, 381.

研究成果: Article

3 引文 斯高帕斯(Scopus)

Apoptotic and nonapoptotic activities of pterostilbene against cancer

Chen, R. J., Kuo, H. C., Cheng, L. H., Lee, Y. H., Chang, W. T., Wang, B. J., Wang, Y. J. & Cheng, H. C., 2018 一月 18, 於 : International journal of molecular sciences. 19, 1, 287.

研究成果: Review article

8 引文 斯高帕斯(Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, Y-M., 2018 六月, 於 : Redox Biology. 16, p. 104-112 9 p.

研究成果: Article

4 引文 斯高帕斯(Scopus)

Autophagy and innate immunity: Insights from invertebrate model organisms

Kuo, C. J., Hansen, M. & Troemel, E., 2018 二月 1, 於 : Autophagy. 14, 2, p. 233-242 10 p.

研究成果: Review article

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13 引文 斯高帕斯(Scopus)

Decreased succinate dehydrogenase B in human hepatocellular carcinoma accelerates tumor malignancy by inducing the Warburg effect

Tseng, P. L., Wu, W. H., Hu, T. H., Chen, C. W., Cheng, H. C., Li, C. F., Tsai, W. H., Tsai, H. J., Hsieh, M. C., Chuang, J. H. & Chang, W. T., 2018 十二月 1, 於 : Scientific reports. 8, 1, 3081.

研究成果: Article

10 引文 斯高帕斯(Scopus)

Design and synthesis of malonamide derivatives as antibiotics against methicillin-resistant staphylococcus aureus

Su, J. C., Huang, Y. T., Chen, C. S., Chiu, H. C. & Shiau, C. W., 2018 一月 1, 於 : Molecules. 23, 1, 27.

研究成果: Article

1 引文 斯高帕斯(Scopus)

Elovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression

Su, Y. C., Feng, Y. H., Wu, H. T., Huang, Y. S., Tung, C. L., Wu, P., Chang, C. J., Shiau, A. L. & Wu, C. L., 2018 十二月 1, 於 : Scientific reports. 8, 1, 6586.

研究成果: Article

5 引文 斯高帕斯(Scopus)

Estrogen and mechanical loading-related regulation of estrogen receptor-β and apoptosis in tendinopathy

Hsieh, J. L., Jou, I. M., Wu, C. L., Wu, P. T., Shiau, A. L., Chong, H. E., Lo, Y. T., Shen, P. C. & Chen, S. Y., 2018 十月, 於 : PloS one. 13, 10, e0204603.

研究成果: Article

1 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)
3 引文 斯高帕斯(Scopus)

IL-20 bone diseases involvement and therapeutic target potential

Wang, H. H., Hsu, Y. H. & Chang, M. S., 2018 四月 24, 於 : Journal of biomedical science. 25, 1, 38.

研究成果: Review article

2 引文 斯高帕斯(Scopus)

Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing

Cheng, T. L., Chen, P. K., Huang, W. K., Kuo, C. H., Cho, C. F., Wang, K. C., Shi, G. Y., Wu, H. L. & Lai, C. H., 2018 十二月 1, 於 : Journal of Molecular Medicine. 96, 12, p. 1333-1344 12 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)

Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity

Tu, L. H., Tseng, N. H., Tsai, Y. R., Lin, T. W., Lo, Y. W., Charng, J. L., Hsu, H. T., Chen, Y. S., Chen, R. J., Wu, Y. T., Chan, Y. T., Chen, C. S., Fang, J. M. & Chen, Y. R., 2018 十月 5, 於 : European Journal of Medicinal Chemistry. 158, p. 393-404 12 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells

Sun, Z., Wang, C. Y., Lawson, D. A., Kwek, S., Velozo, H. G., Owyong, M., Lai, M. D., Fong, L., Wilson, M., Su, H., Werb, Z. & Cooke, D. L., 2018 一月 1, 於 : Oncotarget. 9, 13, p. 10945-10961 17 p.

研究成果: Article

6 引文 斯高帕斯(Scopus)

The chondroitin sulfate moiety mediates thrombomodulin-enhanced adhesion and migration of vascular smooth muscle cells

Pai, V. C., Lo, I. C., Huang, Y. W., Tsai, I. C., Cheng, H. P., Shi, G. Y., Wu, H. L. & Jiang, M. J., 2018 二月 13, 於 : Journal of biomedical science. 25, 1, 306361.

研究成果: Article

1 引文 斯高帕斯(Scopus)

The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition

Tseng, P. L., Chen, C. W., Hu, K. H., Cheng, H. C., Lin, Y. H., Tsai, W. H., Cheng, T. J., Wu, W. H., Yeh, C. W., Lin, C. C., Tsai, H. J., Chang, H. C., Chuang, J. H., Shan, Y. S. & Chang, W. T., 2018 四月 10, 於 : Oncotarget. 9, 27, p. 18949-18969 21 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)

The establishment of a lung colonization assay for circulating tumor cell visualization in lung tissues

Lin, T. C., Liao, Y. C., Chang, W. T., Yang, C. H., Cheng, L. H., Cheng, M. & Cheng, H. C., 2018 六月 18, 於 : Journal of Visualized Experiments. 2018, 136, e56761.

研究成果: Article

4 引文 斯高帕斯(Scopus)

VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function

Wang, Y., Tzeng, H., Tsai, C., Cheng, H., Lai, W., Liu, H. & Wang, Y., 2018 十一月 1, 於 : Cancer Letters. 437, p. 79-88

研究成果: Article

2 引文 斯高帕斯(Scopus)
2017
7 引文 斯高帕斯(Scopus)

Anti-IL-20 monoclonal antibody inhibited inflammation and protected against cartilage destruction in murine models of osteoarthritis

Hsu, Y. H., Yang, Y. Y., Huwang, M. H., Weng, Y. H., Jou, I. M., Wu, P. T., Lin, T. Y., Wu, L. W. & Chang, M. S., 2017 四月, 於 : PloS one. 12, 4, e0175802.

研究成果: Article

7 引文 斯高帕斯(Scopus)

Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma

Chiu, Y. S., Hsing, C. H., Li, C. F., Lee, C. Y., Hsu, Y. H. & Chang, M. S., 2017 十二月 1, 於 : Scientific reports. 7, 1, 17609.

研究成果: Article

2 引文 斯高帕斯(Scopus)

Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells

Hung, Y. H., Huang, H. L., Chen, W. C., Yen, M. C., Cho, C. Y., Weng, T. Y., Wang, C. Y., Chen, Y. L., Chen, L. T. & Lai, M. D., 2017 二月, 於 : Oncology Reports. 37, 2, p. 969-978 10 p.

研究成果: Article

7 引文 斯高帕斯(Scopus)

Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer

Lu, C. S., Shieh, G. S., Wang, C. T., Su, B. H., Su, Y. C., Chen, Y. C., Su, W. C., Wu, P., Yang, W. H., Shiau, A. L. & Wu, C. L., 2017 一月 1, 於 : Oncotarget. 8, 19, p. 30844-30858 15 p.

研究成果: Article

15 引文 斯高帕斯(Scopus)
19 引文 斯高帕斯(Scopus)