生物化學暨分子生物學研究所

研究成果

每年研究成果 1973 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 911 Article
• 81 Patent
• 38 Review article
• 9 Chapter
• 17 更多
  • 6 Comment/debate
  • 5 Conference contribution
  • 4 Editorial
  • 2 Letter

每年研究成果

每年研究成果

搜尋結果

• 2014

  REGULATOR AND PHARMACEUTICAL COMPOSITION ENCOMPASSING THE REGULATOR

  貢獻的翻譯標題: 調控物及含有該調控物之醫藥組合物Chow, N-H., Liu, H-S. & Chang, W-T., 2014 2月 20, 專利號 9180139

  研究成果: Patent

  • Pharmaceutical 100%

• Treatment of Osteoarthritis Using IL-20 Antagonists

  貢獻的翻譯標題: Treatment of Osteoarthritis Using IL-20 AntagonistsChang, M-S., 2014 1月 23, 專利號 9221904

  研究成果: Patent

  • interleukin 20 100%
  • Osteoarthritis 54%
  • Antibodies 22%

• 人類纖維黏蛋白變異體及其醫藥用途

  Chuang, W-J., 2014 4月 1, 專利號 I580692

  研究成果: Patent
• 2013

  DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 去整合蛋白變異體及其醫藥用途Chuang, W-J., 2013 3月 28, 專利號 HK1136160

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%
• 2012

  Disintegrin variants and pharmaceutical uses thereof

  Chuang, W-J., 2012 3月 30, 專利號 577998

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%

• Disintegrin variants and pharmaceutical uses thereof

  Chuang, W-J., 2012 3月 30, 專利號 598176

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%

• 一種用於預防或治療心血管疾病之醫藥組合物

  Wu, H-L., 施桂月, Liu, P-Y., Lin, C-C., Tsai, W-C., Li, Y-H., 林立人 & 陳志鴻, 2012 9月 11, IPC 號 A61K 31/485, 專利號 I372054, 2008 1月 28, 優先日期 2028 1月 27

  研究成果: Patent
• 2011

  COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOGENESIS-RELATED EYE DISEASES

  貢獻的翻譯標題: 治療血管新生相關之眼疾之組合物及方法Chuang, W-J., 2011 11月 16, 專利號 I581801

  研究成果: Patent

• Disintegrin variants and pharmaceutical uses thereof

  Chuang, W-J., 2011 2月 10, 專利號 2477727

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%

• POLYPEPTIDES SELECTIVE FOR αVβ3 INTEGRIN CONJUGATED WITH A VARIANT OF HUMAN SERUM ALBUMIN (HSA) AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 具αｖβ３整合蛋白選擇性且與人類血清白蛋白（ＨＳＡ）變體結合之多?及其於醫藥上之用途Chuang, W-J., 2011 3月 1, 專利號 I557224

  研究成果: Patent

• RNAi compound targeted to thrombospondin-1 and applications thereof

  貢獻的翻譯標題: 第一型血小板活化素siRNA分子及其應用Lai, M-D., 2011 7月 7, 專利號 8377902

  研究成果: Patent

  • Pharmaceutical 100%

• Use of Anti-IL-20 antibody for treating rheumatoid arthrits and osteoporosis

  貢獻的翻譯標題: Use of Anti-IL-20 antibody for treating rheumatoid arthrits and osteoporosisChang, M-S., 2011 3月 17, 專利號 8454956

  研究成果: Patent

  • antibody 100%

• Use of Anti-IL-20 antibody for treating rheumatoid arthrits and osteoporosis

  Chang, M-S., 2011 1月 6, 專利號 8206712

  研究成果: Patent

  • interleukin 20 100%
  • Etanercept 76%
  • Osteoporosis 53%
  • Rheumatoid Arthritis 50%
  • Peptides 38%
• 2010

  Use of Anti-IL-20 antibody for treating osteoporosis (as amended)

  Chang, M-S., 2010 4月 8, 專利號 7837994

  研究成果: Patent

  • interleukin 20 100%
  • Etanercept 76%
  • Osteoporosis 53%
  • Rheumatoid Arthritis 50%
  • Peptides 38%

• Use of Anti-IL-20 antibody for treating stroke

  貢獻的翻譯標題: Use of Anti-IL-20 antibody for treating strokeChang, M-S., 2010 4月 8, 專利號 8012478

  研究成果: Patent

  • interleukin 20 100%
  • Bone Neoplasms 74%
  • Anti-Idiotypic Antibodies 51%
  • Stroke 41%
  • Antibodies 33%
• 2009

  Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseases

  貢獻的翻譯標題: Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseasesChang, M-S., 2009 2月 19, 專利號 7786274

  研究成果: Patent

  • interleukin 20 100%
  • Psoriatic Arthritis 36%
  • Antibodies 33%
  • Stomach Ulcer 33%
  • Psoriasis 29%

• Disintegrin variants and pharmaceutical uses thereof

  Chuang, W-J., 2009 7月 29, 專利號 153383

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%

• Disintegrin variants and pharmaceutical uses thereof

  Chuang, W-J., 2009 10月 13, 專利號 291711

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%

• DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 去整合蛋白變異體及其醫藥用途Chuang, W-J., 2009 7月 23, 專利號 60/871,854

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%

• DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 去整合蛋白變異體及其醫藥用途Chuang, W-J., 2009 12月 2, 專利號 EP 2124548

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%
• 2008

  Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseases

  貢獻的翻譯標題: Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseasesChang, M-S., 2008 12月 18, 專利號 7611705

  研究成果: Patent

  • interleukin 20 100%
  • Psoriatic Arthritis 36%
  • Antibodies 33%
  • Stomach Ulcer 33%
  • Psoriasis 29%

• DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 去整合蛋白變異體及其醫藥用途Chuang, W-J., 2008 8月 7, 專利號 7943728

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 47%
  • Pharmaceutical Preparations 31%
  • Peptides 16%
• 2006

  interleukin-20,monoclonal antibody 7e, and uses thereof

  貢獻的翻譯標題: Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferationChang, M-S., 2006 6月 29, 專利號 7435800

  研究成果: Patent

  • interleukins 100%
  • monoclonal antibodies 75%
  • antibodies 55%
  • bones 35%
  • neoplasms 32%
• 2005

  DNA vaccine containing tumor-associated gene and cytokine ene and method of preparation

  貢獻的翻譯標題: 具有腫瘤相關基因與細胞激素基因之DNA疫苗及其合成方法Lai, M-D., 2005 1月 27, 專利號 7132407

  研究成果: Patent

  • Cytokines 50%
  • Genetic Recombination 39%
  • Genes 33%
  • Neoplasms 26%
  • DNA 22%
• 1800

  A DNA VACCINE CONTAINING A TUMOR ASSOCIATED GENE AND A CYTOKINE GENE AND THE METHOD PRODUCING THEREOF

  貢獻的翻譯標題: 具有腫瘤相關基因與細胞激素基因之DNA疫苗及其合成方法Lai, M-D., 1800, 專利號 I259206

  研究成果: Patent

• Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseases

  貢獻的翻譯標題: Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseasesChang, M-S., 1800, 專利號 特許第5167408號

  研究成果: Patent

  • interleukin 20 100%
  • Bone Neoplasms 74%
  • Anti-Idiotypic Antibodies 51%
  • Antibodies 33%

• APPLICATION OF IRON-GOLD CORE-SHELL NANOPARTICLES IN TUMOR THERAPEUTICS

  貢獻的翻譯標題: 鐵/金核殼型複合奈米粒子於治療腫瘤之用途Wu, C-L., Yeh, C-S., Chen, D-H., Chou, C-H. & Shieh, D-B., 1800, 專利號 I295177

  研究成果: Patent

• Complex for preparing influenza vaccine, novel influenza vaccine, and method for manufacturing the same

  貢獻的翻譯標題: 用以製備流感疫苗之複合物、新型流感疫苗及其製備方法Wu, C-L., Shiau, A-L. & Chen, Y-H., 1800, 專利號 I493038

  研究成果: Patent

• Disintegrin variants and pharmaceutical uses thereof

  貢獻的翻譯標題: 去整合蛋白變異體及其醫藥用途Chuang, W-J., 1800, 專利號 I392738

  研究成果: Patent

• DISINTEGRIN VARIANTS AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 去整合蛋白變異體及其醫藥用途Chuang, W-J., 1800, 專利號 8183201

  研究成果: Patent

  • Disintegrins 100%
  • Integrins 71%
  • Pharmaceutical Preparations 31%
  • Proteins 18%
  • Peptides 16%

• GALECTIN-1-GOLD PARTICLE COMPLEX AND APPLICATIONS THEREOF

  貢獻的翻譯標題: 半乳糖凝集素-1-金粒子複合物及其應用Wu, C-L., Shiau, A-L. & Wang, C-R., 1800, 專利號 I466894

  研究成果: Patent

• HUMANIZED ANTI-IL-20 ANTIBODY AND USES THEREOF

  貢獻的翻譯標題: HUMANIZED ANTI-IL-20 ANTIBODY AND USES THEREOFChang, M-S., 1800, 專利號 8597647

  研究成果: Patent

  • interleukin 20 100%
  • Antibodies, Monoclonal, Humanized 39%
  • Antibodies 33%
  • Disclosure 33%
  • Osteoporosis 26%

• HUMANIZED ANTI-IL-20 ANTIBODY AND USES THEREOF

  貢獻的翻譯標題: HUMANIZED ANTI-IL-20 ANTIBODY AND USES THEREOFChang, M-S., 1800, 專利號 9217031

  研究成果: Patent

  • interleukin 20 100%
  • Antibodies, Monoclonal, Humanized 39%
  • Antibodies 33%
  • Disclosure 33%
  • Osteoporosis 26%

• Method and biomarker for evaluating cancer metastasis, and siRNA compound for inhibiting cancer metastasis

  貢獻的翻譯標題: 癌症轉移之評估方法及生物標記、及抑制癌症轉移之siRNA化合物Liao, P-C. & Cheng, H-C., 1800, 專利號 I484183

  研究成果: Patent

• Method for preparation of water-soluble and dispersed iron oxide nanoparticles and application thereof

  貢獻的翻譯標題: 水溶性及分散性之氧化鐵奈米粒子之製造方法及其應用Wu, C-L., Yeh, C-S. & Shieh, D-B., 1800, 專利號 202070

  研究成果: Patent

• Method for Preparation of Water-Soluble and Dispersed Iron Oxide Nanoparticles and Application Thereof

  貢獻的翻譯標題: 水溶性及分散性之氧化鐵奈米粒子之製造方法及其應用Wu, C-L., Yeh, C-S. & Shieh, D-B., 1800, 專利號 10 2004 035 803

  研究成果: Patent

• METHODS FOR TREATING OSTEOPOROSIS WITH ANTI-IL-20 RECEPTOR ANTIBODIES

  貢獻的翻譯標題: METHODS FOR TREATING OSTEOPOROSIS WITH ANTI-IL-20 RECEPTOR ANTIBODIESChang, M-S., 1800, 專利號 9127066

  研究成果: Patent

  • interleukin-20 receptor 100%
  • Osteoporosis 45%
  • Antibodies 28%
  • interleukin 20 21%
  • Diabetic Nephropathies 13%

• PHARMACEUTICAL CARRIER FOR RECOGNIZING CARCINOMA AND PHARMACEUTICAL COMPOSITION FOR TREATING CARCINOMA

  貢獻的翻譯標題: 辨識癌細胞之醫藥載體及治療癌細胞之醫藥組成物Cheng, H-C., 1800, 專利號 I463992

  研究成果: Patent

• PHARMACEUTICAL COMPOSITION FOR DIAGNOSING CARCINOMA METASTASIS

  貢獻的翻譯標題: 用以診斷癌細胞轉移之醫藥組成物Cheng, H-C., 1800, 專利號 I532995

  研究成果: Patent

• PHARMACEUTICAL COMPOSITION FOR INHIBITING THE FUNCTION OF VASCULAR ENDOTHELIAL.

  貢獻的翻譯標題: 用以抑制血管內皮細胞生長因子作用之醫藥組合物Wu, C-L., 1800, 專利號 I369209

  研究成果: Patent

• Polypeptide for inhibiting metastasis, use thereof, and pharmaceutical composition containing the same

  貢獻的翻譯標題: 抑制癌細胞轉移之多?、其用途、及包含其之醫藥組成物Cheng, H-C., 1800, 專利號 I472337

  研究成果: Patent

• POLYPEPTIDES SELECTIVE FOR αVβ3 INTEGRIN CONJUGATED WITH A VARIANT OF HUMAN SERUM ALBUMIN (HSA) AND PHARMACEUTICAL USES THEREOF

  貢獻的翻譯標題: 具αｖβ３整合蛋白選擇性且與人類血清白蛋白（ＨＳＡ）變體結合之多?及其於醫藥上之用途Chuang, W-J., 1800, 專利號 AR077764A1

  研究成果: Patent

• Regulator And Pharmaceutical Composition Encompassing The Regulator

  貢獻的翻譯標題: 調控物及含有該調控物的醫藥組合物Chow, N-H., Liu, H-S. & Chang, W-T., 1800, 專利號 ZL 2013 1 0177660.2

  研究成果: Patent

  • Pharmaceutical 100%

• REGULATOR AND PHARMACEUTICAL COMPOSITION ENCOMPASSING THE REGULATOR

  貢獻的翻譯標題: 調控物及含有該調控物之醫藥組合物Chow, N-H., Liu, H-S. & Chang, W-T., 1800, 專利號 I474819

  研究成果: Patent

• Treating allergic airway disorders using anti-IL-20 receptor antibodies

  Chang, M-S., 1800, 專利號 8852588

  研究成果: Patent

  • interleukin-20 receptor 100%
  • Airway Obstruction 54%
  • Asthma 40%
  • Antibodies 28%

• Treating Breast Cancer and Inhibiting Cancer-Associated Bone Loss With Anti-IL-20 Antibody

  貢獻的翻譯標題: Treating Breast Cancer and Inhibiting Cancer-Associated Bone Loss With Anti-IL-20 AntibodyChang, M-S., 1800, 專利號 8535674

  研究成果: Patent

• Treating Breast Cancer with Anti-IL-19 Antibody

  Chang, M-S., 1800, 專利號 8377441

  研究成果: Patent

  • antibodies 57%

• Treating Breast Cancer with Anti-IL-19 Antibody

  貢獻的翻譯標題: 治療乳癌之抗介白素-19抗體之醫藥組合物Chang, M-S., 1800, 專利號 8377441

  研究成果: Patent

• Treating Breast Cancer With Anti-IL-19 Antibody

  Chang, M-S., 1800, 專利號 2600896

  研究成果: Patent

  • antibodies 57%

• Treating Breast Cancer With Anti-IL-19 Antibody

  Chang, M-S., 1800, 專利號 2600896

  研究成果: Patent