微生物學科暨微生物及免疫學研究所

研究成果

2020

Bortezomib induces HSV-1 lethality in mice with neutrophil deficiency

Yao, H. W., Wang, L. C., Tsai, H. Y., Fang, Y. H., Zheng, C., Chen, S. H. & Hsu, S. M., 2020 一月 1, 於 : Journal of Leukocyte Biology. 107, 1, p. 105-112 8 p.

研究成果: Article

Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity

Kang, C. Y., Huang, I. H., Chou, C. C., Wu, T. Y., Chang, J. C., Hsiao, Y. Y., Cheng, C. H., Tsai, W. J., Hsu, K. C. & Wang, S., 2020 三月 13, 於 : Journal of Biological Chemistry. 295, 11, p. 3734-3745 12 p.

研究成果: Article

Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells

Hsieh, C. L., Hsieh, S. Y., Huang, H. M., Lu, S. L., Omori, H., Zheng, P. X., Ho, Y. N., Cheng, Y. L., Lin, Y. S., Chiang-Ni, C., Tsai, P. J., Wang, S. Y., Liu, C. C., Noda, T. & Wu, J. J., 2020 二月 11, 於 : Frontiers in Microbiology. 11, 117.

研究成果: Article

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ST2 Signaling in the Tumor Microenvironment

Chang, C. P., Hu, M. H., Hsiao, Y. P. & Wang, Y. C., 2020 一月 1, Advances in Experimental Medicine and Biology. Springer, p. 83-93 11 p. (Advances in Experimental Medicine and Biology; 卷 1240).

研究成果: Chapter

2019
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1 引文 斯高帕斯(Scopus)
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1 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

Combination of modified NS1 and NS3 as a novel vaccine strategy against dengue virus infection

Kao, Y. S., Yu, C. Y., Huang, H. J., Tien, S. M., Wang, W. Y., Yang, M., Anderson, R., Yeh, T. M., Lin, Y. S. & Wan, S. W., 2019 十月 1, 於 : Journal of Immunology. 203, 7, p. 1909-1917 9 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)

Curcumin functions as a MEK inhibitor to induce a synthetic lethal effect on KRAS mutant colorectal cancer cells receiving targeted drug regorafenib

Wu, C. S., Wu, S. Y., Chen, H. C., Chu, C. A., Tang, H. H., Liu, H. S., Hong, Y. R., Huang, C. Y. F., Huang, G. C. & Su, C. L., 2019 十二月, 於 : Journal of Nutritional Biochemistry. 74, 108227.

研究成果: Article

Degradative autophagy selectively regulates CCND1 (cyclin D1) and MIR224, two oncogenic factors involved in hepatocellular carcinoma tumorigenesis

Wu, S. Y., Lan, S. H. & Liu, H. S., 2019 四月 3, 於 : Autophagy. 15, 4, p. 729-730 2 p.

研究成果: Comment/debate

5 引文 斯高帕斯(Scopus)

Expression of prothymosin α in lung cancer is associated with squamous cell carcinoma and smoking

Kuo, Y. H., Shiau, A. L., Tung, C. L., Su, Y. C., Li, C. F., Su, B. H., Tsao, C. J., Wu, C. L., Feng, Y. H. & Wu, P., 2019 六月, 於 : Oncology Letters. 17, 6, p. 5740-5746 7 p.

研究成果: Article

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Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling

Ge, J., Remesh, S. G., Hammel, M., Pan, S., Mahan, A. D., Wang, S. & Wang, X., 2019 八月 6, 於 : Structure. 27, 8, p. 1296-1307.e5

研究成果: Article

Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy

Cheng, Y. L., Kuo, C. F., Lu, S. L., Hiroko, O., Wu, Y. N., Hsie, C. L., Nod, T., Wu, S. R., Anderson, R., Lin, C. F., Chen, C. L., Wu, J. J. & Lin, Y. S., 2019 一月 1, 於 : mBio. 10, 5, e02148-19.

研究成果: Article

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1 引文 斯高帕斯(Scopus)

HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection

Tseng, P. C., Kuo, C. F., Cheng, M. H., Wan, S. W., Lin, C. F., Chang, C. P., Lin, Y. S., Wu, J. J., Huang, C. C. & Chen, C. L., 2019 九月 18, 於 : Frontiers in Immunology. 10, 2147.

研究成果: Article

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Implantable microneedles with an immune-boosting function for effective intradermal influenza vaccination

Chen, Y. H., Lai, K. Y., Chiu, Y. H., Wu, Y. W., Shiau, A-L. & Chen, M-C., 2019 十月 1, 於 : Acta Biomaterialia. 97, p. 230-238 9 p.

研究成果: Article

Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps

Pu, C. M., Chen, Y. C., Chen, Y. C., Lee, T. L., Peng, Y. S., Chen, S. H., Yen, Y. H., Chien, C. L., Hsieh, J. H. & Chen, Y. L., 2019 一月 1, 於 : Mediators of Inflammation. 2019, 2343867.

研究成果: Article

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Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats

Kuthati, Y., Davuluri, V. N. G., Yang, C. P., Chang, H. C., Chang, C. P. & Wong, C. S., 2019 一月 1, 於 : Journal of Pain Research. 12, p. 2473-2485 13 p.

研究成果: Article

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1 引文 斯高帕斯(Scopus)
4 引文 斯高帕斯(Scopus)
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4 引文 斯高帕斯(Scopus)

MST3 is involved in ENaC-mediated hypertension

Lu, T. J., Kan, W. C., Yang, S. S., Jiang, S. T., Wu, S. N., Ling, P., Bao, B. Y., Lin, C. Y., Yang, Z. Y., Weng, Y. P., Chan, C. H. & Lu, T. L., 2019 一月 1, 於 : American Journal of Physiology - Renal Physiology. 317, 7, p. F30-F42

研究成果: Article

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Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Feng, Y. H., Su, Y. C., Lin, S. F., Lin, P. R., Wu, C. L., Tung, C. L., Li, C. F., Shieh, G. S. & Shiau, A. L., 2019 八月 9, 於 : BMC cancer. 19, 1, 791.

研究成果: Article

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1 引文 斯高帕斯(Scopus)

Prothymosin α promotes STAT3 acetylation to induce cystogenesis in Pkd1-deficient mice

Chen, Y. C., Su, Y. C., Shieh, G. S., Su, B. H., Su, W. C., Huang, P. H., Jiang, S. T., Shiau, A. L. & Wu, C. L., 2019 十一月 1, 於 : FASEB Journal. 33, 11, p. 13051-13061 11 p.

研究成果: Article

2 引文 斯高帕斯(Scopus)

Swimming pool-associated Vittaforma-like microsporidia linked to microsporidial keratoconjunctivitis outbreak, Taiwan

Chen, J. S., Hsu, T. K., Hsu, B. M., Chao, S. C., Huang, T. Y., Ji, D. D., Yang, P. Y. & Huang, I. H., 2019 一月 1, 於 : Emerging infectious diseases. 25, 11, p. 2100-2103 4 p.

研究成果: Article

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2018

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli

Kuo, C. J., Wang, S. T., Lin, C. M., Chiu, H. C., Huang, C. R., Lee, D. Y., Chang, G. D., Chou, T. C., Chen, J. W. & Chen, C. S., 2018 三月 1, 於 : Cell Death and Disease. 9, 3, 381.

研究成果: Article

4 引文 斯高帕斯(Scopus)
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1 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

Kurhade, C., Schreier, S., Lee, Y. P., Zegenhagen, L., Hjertqvist, M., Dobler, G., Kröger, A. & Överby, A. K., 2018 九月, 於 : Emerging infectious diseases. 24, 9, p. 1709-1712 4 p.

研究成果: Article

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2 引文 斯高帕斯(Scopus)

Dengue virus-induced ER stress is required for autophagy activation, viral replication, and pathogenesis both in vitro and in vivo

Lee, Y. R., Kuo, S. H., Lin, C. Y., Fu, P. J., Lin, Y. S., Yeh, T. M. & Liu, H. S., 2018 十二月 1, 於 : Scientific reports. 8, 1, 489.

研究成果: Article

25 引文 斯高帕斯(Scopus)

Dextromethorphan attenuates NADPH oxidase-regulated glycogen synthase kinase 3 and NF-B activation and reduces nitric oxide production in group a streptococcal infection

Chen, C. L., Cheng, M. H., Kuo, C. F., Cheng, Y. L., Li, M. H., Chang, C. P., Wu, J. J., Anderson, R., Wang, S., Tsai, P-J., Liu, C. C. & Linc, Y. S., 2018 六月, 於 : Antimicrobial agents and chemotherapy. 62, 6, e02045-17.

研究成果: Article

5 引文 斯高帕斯(Scopus)

Elovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression

Su, Y. C., Feng, Y. H., Wu, H. T., Huang, Y. S., Tung, C. L., Wu, P., Chang, C. J., Shiau, A. L. & Wu, C. L., 2018 十二月 1, 於 : Scientific reports. 8, 1, 6586.

研究成果: Article

5 引文 斯高帕斯(Scopus)

Estrogen and mechanical loading-related regulation of estrogen receptor-β and apoptosis in tendinopathy

Hsieh, J. L., Jou, I. M., Wu, C. L., Wu, P. T., Shiau, A. L., Chong, H. E., Lo, Y. T., Shen, P. C. & Chen, S. Y., 2018 十月, 於 : PloS one. 13, 10, e0204603.

研究成果: Article

1 引文 斯高帕斯(Scopus)

Genetic relationships among multidrug-resistant salmonella enterica serovar typhimurium strains from humans and animals

Hong, Y. P., Wang, Y. W., Huang, I. H., Liao, Y. C., Kuo, H. C., Liu, Y. Y., Tu, Y. H., Chen, B. H., Liao, Y. S. & Chiou, C. S., 2018 五月, 於 : Antimicrobial agents and chemotherapy. 62, 5, e00213.

研究成果: Article

5 引文 斯高帕斯(Scopus)

Hepatocellular carcinoma–related cyclin D1 is selectively regulated by autophagy degradation system

Wu, S. Y., Lan, S. H., Wu, S. R., Chiu, Y. C., Lin, X. Z., Su, I. J., Tsai, T. F., Yen, C. J., Lu, T. H., Liang, F. W., Li, C. Y., Su, H. J., Su, C. L. & Liu, H. S., 2018 七月, 於 : Hepatology. 68, 1, p. 141-154 14 p.

研究成果: Article

20 引文 斯高帕斯(Scopus)

Herpes simplex virus 1 tegument protein VP22 abrogates cGAS/ STING-mediated antiviral innate immunity

Huang, J., You, H., Su, C., Li, Y., Chen, S. & Zheng, C., 2018 八月 1, 於 : Journal of Virology. 92, 15, e00841-18.

研究成果: Article

21 引文 斯高帕斯(Scopus)

In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking

Chang, C., Amer, B. R., Osipiuk, J., McConnell, S. A., Huang, I. H., Hsieh, V., Fu, J., Nguyen, H. H., Muroski, J., Flores, E., Loo, R. R. O., Loo, J. A., Putkey, J. A., Joachimiak, A., Das, A., Clubb, R. T. & Ton-That, H., 2018 六月 12, 於 : Proceedings of the National Academy of Sciences of the United States of America. 115, 24, p. E5477-E5486

研究成果: Article

2 引文 斯高帕斯(Scopus)

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model

Yang, H. T., Chen, J. W., Rathod, J., Jiang, Y. Z., Tsai, P. J., Hung, Y. P., Ko, W. C., Paredes-Sabja, D. & Huang, I. H., 2018 一月 17, 於 : Frontiers in Microbiology. 8, JAN, 2635.

研究成果: Article

11 引文 斯高帕斯(Scopus)
8 引文 斯高帕斯(Scopus)
5 引文 斯高帕斯(Scopus)

MST3 (mammalian Ste20-like protein kinase 3), a novel gene involved in ion homeostasis and renal regulation of blood pressure in spontaneous hypertensive rats

Lu, T. J., Chan, C. H., Ling, P., Chao, Y. M., Bao, B. Y., Chiang, C. Y., Lee, T. H., Weng, Y. P., Kan, W. C. & Lu, T. L., 2018 十二月 1, 於 : International Urology and Nephrology. 50, 12, p. 2299-2307 9 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)
3 引文 斯高帕斯(Scopus)

Photodynamic inactivation of methicillin-resistant Staphylococcus aureus by indocyanine green and near infrared light

Wong, T. W., Wu, E. C., Ko, W. C., Lee, C. C., Hor, L. I. & Huang, I. H., 2018 三月, 於 : Dermatologica Sinica. 36, 1, p. 8-15 8 p.

研究成果: Article

4 引文 斯高帕斯(Scopus)

PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-ΚB-dependent pathway

Liu, C. W., Lee, T. L., Chen, Y. C., Liang, C. J., Wang, S. H., Lue, J. H., Tsai, J. S., Lee, S. W., Chen, S. H., Yang, Y. F., Chuang, T. Y. & Chen, Y. L., 2018 一月 12, 於 : Particle and Fibre Toxicology. 15, 1, 4.

研究成果: Article

35 引文 斯高帕斯(Scopus)

Sera of patients with systemic lupus erythematosus cross-neutralizes dengue viruses

Zainal, N., Tan, K. K., Johari, J., Hussein, H., Wan Musa, W. R., Hassan, J., Lin, Y. S. & AbuBakar, S., 2018 十月, 於 : Microbiology and Immunology. 62, 10, p. 659-672 14 p.

研究成果: Article