每年研究成果
每年研究成果
搜尋結果
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2021
APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
Liu, T. C., Lin, C. T., Chang, K. C., Guo, K. W., Wang, S., Chu, J. W. & Hsiao, Y. Y., 2021 一月 27, 於: Nature communications. 12, 1, 601.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Clostridioides difficile spores stimulate inflammatory cytokine responses and induce cytotoxicity in macrophages
Chiu, P. J., Jagat, R., Hong, Y. P., Tsai, P. J., Hung, Y. P., Ko, W. C., Chen, J-W., Paredes-Sabja, D. & Huang, I-H., 2021 八月, 於: Anaerobe. 70, 102381.研究成果: Article › 同行評審
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Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcription axes elicit an immunosuppressive lung tumor microenvironment
Kuo, I. Y., Yang, Y. E., Yang, P. S., Tsai, Y. J., Tzeng, H. T., Cheng, H. C., Kuo, W. T., Su, W. C., Chang, C. P. & Wang, Y. C., 2021, 於: Theranostics. 11, 14, p. 7029-7044 16 p.研究成果: Article › 同行評審
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Correlation between pathogenic determinants associated with clinically isolated non-typhoidal Salmonella
Ouali, B. E. F., Chiou, T. H., Chen, J. W., Lin, I. C., Liu, C. C., Chiang, Y. C., Ho, T. S. & Wang, H. V., 2021 一月, 於: Pathogens. 10, 1, p. 1-16 16 p., 74.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Early-life EV-A71 infection augments allergen-induced airway inflammation in asthma through trained macrophage immunity
Chen, P. C., Shao, Y. T., Hsieh, M. H., Kao, H. F., Kuo, W. S., Wang, S. M., Chen, S. H., Wu, L. S. H., Tsai, H. J. & Wang, J. Y., 2021 二月, 於: Cellular and Molecular Immunology. 18, 2, p. 472-483 12 p.研究成果: Article › 同行評審
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Glycosyltransferase Jhp0106 (PseE) contributes to flagellin maturation in Helicobacter pylori
Yang, K. Y., Kao, C. Y., Su, M. S. W., Wang, S., Chen, Y. L., Hu, S. T., Chen, J. W., Teng, C. H., Tsai, P. J. & Wu, J. J., 2021 四月, 於: Helicobacter. 26, 2, e12787.研究成果: Article › 同行評審
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Honeysuckle aqueous extracts induced let-7a suppress ev71 replication and pathogenesis in vitro and in vivo and is predicted to inhibit sars-cov-2
Lee, Y. R., Chang, C. M., Yeh, Y. C., Huang, C. Y. F., Lin, F. M., Huang, J. T., Hsieh, C. C., Wang, J. R. & Liu, H. S., 2021 二月, 於: Viruses. 13, 2, 308.研究成果: Article › 同行評審
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Mab_3083c is a homologue of RNase J and plays a role in colony morphotype, aggregation, and sliding motility of mycobacterium abscessus
Liu, T. Y., Tsai, S. H., Chen, J. W., Wang, Y. C., Hu, S. T. & Chen, Y. Y., 2021, 於: Microorganisms. 9, 4, 676.研究成果: Article › 同行評審
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OmpR coordinates the expression of virulence factors of Enterohemorrhagic Escherichia coli in the alimentary tract of Caenorhabditis elegans
Wang, S. T., Kuo, C. J., Huang, C. W., Lee, T. M., Chen, J. W. & Chen, C. S., 2021, (Accepted/In press) 於: Molecular Microbiology.研究成果: Article › 同行評審
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Up-regulated expression of pro-apoptotic long noncoding RNA lincrna-P21 with enhanced cell apoptosis in lupus nephritis
Chen, Y. C., Kuo, P. Y., Chou, Y. C., Chong, H. E., Hsieh, Y. T., Yang, M. L., Wu, C. L., Shiau, A. L. & Wang, C. R., 2021 一月 1, 於: International journal of molecular sciences. 22, 1, p. 1-18 18 p., 301.研究成果: Article › 同行評審
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2020
Antibiotic-resistant escherichia coli and sequence type 131 in fecal colonization in dogs in taiwan
Chen, J. W., Huang, H. H., Chang, S. M., Scaria, J., Chiu, Y. L., Chen, C. M., Ko, W. C. & Wang, J. L., 2020 九月, 於: Microorganisms. 8, 9, p. 1-9 9 p., 1439.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Bortezomib induces HSV-1 lethality in mice with neutrophil deficiency
Yao, H. W., Wang, L. C., Tsai, H. Y., Fang, Y. H., Zheng, C., Chen, S. H. & Hsu, S. M., 2020 一月 1, 於: Journal of Leukocyte Biology. 107, 1, p. 105-112 8 p.研究成果: Article › 同行評審
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Chitosan oligosaccharides suppress nuclear factor-Kappa B activation and ameliorate experimental autoimmune uveoretinitis in mice
Hsu, S. M., Yang, C. H., Tsai, H. Y., Lin, C. J., Fang, Y. H., Shieh, C. C. & Chen, S. H., 2020 十一月 1, 於: International journal of molecular sciences. 21, 21, p. 1-11 11 p., 8326.研究成果: Article › 同行評審
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CjrABC-senB hinders survival of extraintestinal pathogenic E. coli in the bloodstream through triggering complement-mediated killing
Huang, W. C., Liao, Y. J., Hashimoto, M., Chen, K. F., Chu, C., Hsu, P. C., Wang, S. & Teng, C. H., 2020 八月 6, 於: Journal of biomedical science. 27, 1, 86.研究成果: Article › 同行評審
開啟存取3 引文 斯高帕斯（Scopus） -
Dengue nonstructural protein 1 maintains autophagy through retarding caspase-mediated cleavage of beclin-1
Lu, Z. Y., Cheng, M. H., Yu, C. Y., Lin, Y. S., Yeh, T. M., Chen, C. L., Chen, C. C., Wan, S. W. & Chang, C. P., 2020 十二月 2, 於: International journal of molecular sciences. 21, 24, p. 1-19 19 p., 9702.研究成果: Article › 同行評審
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Effects of Acanthamoeba castellanii on the dissolved oxygen and the microbial community under the experimental aquatic model
Tsai, C. M., Chen, J. W. & Lin, W. C., 2020 十一月, 於: Experimental Parasitology. 218, 107985.研究成果: Article › 同行評審
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Emergence of macrolide-resistant Streptococcus pyogenes emm12 in southern Taiwan from 2000 to 2019
Tsai, W. C., Shen, C. F., Lin, Y. L., Shen, F. C., Tsai, P. J., Wang, S. Y., Lin, Y. S., Wu, J. J., Chi, C. Y. & Liu, C. C., 2020, (Accepted/In press) 於: Journal of Microbiology, Immunology and Infection.研究成果: Article › 同行評審
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EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages
Chuang, J. P., Kao, C. Y., Lee, J. C., Ling, P., Maa, M. C. & Leu, T. H., 2020 九月 24, 於: Biochemical and Biophysical Research Communications. 530, 3, p. 487-493 7 p.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Functional analysis of Clostridium difficile sortase B reveals key residues for catalytic activity and substrate specificity
Kang, C. Y., Huang, I. H., Chou, C. C., Wu, T. Y., Chang, J. C., Hsiao, Y. Y., Cheng, C. H., Tsai, W. J., Hsu, K. C. & Wang, S., 2020 三月 13, 於: Journal of Biological Chemistry. 295, 11, p. 3734-3745 12 p.研究成果: Article › 同行評審
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Hepatocellular carcinoma-derived high mobility group box 1 triggers M2 macrophage polarization via a TLR2/NOX2/autophagy axis
Shiau, D. J., Kuo, W. T., Davuluri, G. V. N., Shieh, C. C., Tsai, P. J., Chen, C. C., Lin, Y. S., Wu, Y. Z., Hsiao, Y. P. & Chang, C. P., 2020 十二月 1, 於: Scientific reports. 10, 1, 13582.研究成果: Article › 同行評審
開啟存取4 引文 斯高帕斯（Scopus） -
Identification of MltG as a Prc Protease Substrate Whose Dysregulation Contributes to the Conditional Growth Defect of Prc-Deficient Escherichia coli
Hsu, P. C., Chen, C. S., Wang, S., Hashimoto, M., Huang, W. C. & Teng, C. H., 2020 八月 27, 於: Frontiers in Microbiology. 11, 2000.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Loss of EGR-1 uncouples compensatory responses of pancreatic β cells
Leu, S. Y., Kuo, L. H., Weng, W. T., Lien, I. C., Yang, C. C., Hsieh, T. T., Cheng, Y. N., Chien, P. H., Ho, L. C., Chen, S. H., Shan, Y. S., Chen, Y. W., Tsai, P. J., Sung, J. M. & Tsai, Y. S., 2020, 於: Theranostics. 10, 9, p. 4233-4249 17 p.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly
Chang, H. Y., Lee, C. H., Li, Y. S., Huang, J. T., Lan, S. H., Wang, Y. F., Lai, W. W., Wang, Y. C., Lin, Y. J., Liu, H. S. & Cheng, H. C., 2020 十二月, 於: Journal of biomedical science. 27, 1, 102.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells
Hsieh, C. L., Hsieh, S. Y., Huang, H. M., Lu, S. L., Omori, H., Zheng, P. X., Ho, Y. N., Cheng, Y. L., Lin, Y. S., Chiang-Ni, C., Tsai, P. J., Wang, S. Y., Liu, C. C., Noda, T. & Wu, J. J., 2020 二月 11, 於: Frontiers in Microbiology. 11, 117.研究成果: Article › 同行評審
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Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer
Lu, C. S., Shiau, A. L., Su, B. H., Hsu, T. S., Wang, C. T., Su, Y. C., Tsai, M. S., Feng, Y. H., Tseng, Y. L., Yen, Y. T., Wu, C. L., Shieh, G. S. & Shieh, G. S., 2020 六月 1, 於: Journal of Hematology and Oncology. 13, 1, 62.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Prothymosin α activates type i collagen to develop a fibrotic placenta in gestational diabetes
Wu, H. T., Kang, L., Su, Y. C., Ou, H. Y., Chan, F. Y., Chen, Y. C., Su, B. H., Wang, Y. S., Wu, C. L., Shiau, A. L. & Wu, P., 2020 九月, 於: Clinical Science. 134, 18, p. 2435-2445 11 p.研究成果: Article › 同行評審
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ProT-α gene transfer attenuates cardiopulmonary remedying and mortality in a flow-induced pulmonary hypertension rat model
Roan, J. N., Hsu, C. H., Fang, S. Y., Chiu, M. S., Wu, C. L., Shiau, A. L. & Lam, C. F., 2020 十月, 於: Journal of Heart and Lung Transplantation. 39, 10, p. 1126-1135 10 p.研究成果: Article › 同行評審
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Pterostilbene sensitizes cisplatin-resistant human bladder cancer cells with oncogenic HRAS
Chen, Y. T., Huang, Z. Y., Tang, H. H., Kuo, W. T., Wu, S. Y., Lan, S. H., Chang, K. H., Lin, P. L., Lee, M. F., Cheng, H. C., Liu, H. S., Huang, C. Y. F., Huang, G. C. & Su, C. L., 2020 十月, 於: Cancers. 12, 10, p. 1-25 25 p., 2869.研究成果: Article › 同行評審
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Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection
Lee, Y. R., Wu, S. Y., Chen, R. Y., Lin, Y. S., Yeh, T. M. & Liu, H. S., 2020 十一月, 於: Kaohsiung Journal of Medical Sciences. 36, 11, p. 911-919 9 p.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Suppression of the reactive oxygen response alleviates experimental autoimmune uveitis in mice
Hsu, S. M., Yang, C. H., Teng, Y. T., Tsai, H. Y., Lin, C. Y., Lin, C. J., Shieh, C. C. & Chen, S. H., 2020 五月 1, 於: International journal of molecular sciences. 21, 9, 3261.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
The cellular immunophenotype expression of influenza A virus and influenza B virus infection in children
Shen, C. F., Ho, T. S., Wang, S. M., Liao, Y. T., Hu, Y. S., Tsai, H. P. & Chen, S. H., 2020 十月, 於: Clinical Immunology. 219, 108548.研究成果: Article › 同行評審
1 引文 斯高帕斯（Scopus） -
UvrY is required for the full virulence of Aeromonas dhakensis
Chen, Y. W., Yeh, W. H., Tang, H. J., Chen, J. W., Shu, H. Y., Su, Y. C., Wang, S. T., Kuo, C. J., Chuang, Y. C., Chen, C. C., Ko, W. C., Chen, C. S. & Chen, P. L., 2020 一月 1, 於: Virulence. 11, 1, p. 502-520 19 p.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3β-mediated epileptic seizure activity in mice
Cheng, Y. Y., Chou, Y. T., Lai, F. J., Jan, M. S., Chang, T. H., Jou, I. M., Chen, P. S., Lo, J. Y., Huang, S. S., Chang, N. S., Liou, Y. T., Hsu, P. C., Cheng, H. C., Lin, Y. S. & Hsu, L. J., 2020 一月 30, 於: Acta Neuropathologica Communications. 8, 1, 6.研究成果: Article › 同行評審
開啟存取3 引文 斯高帕斯（Scopus） -
2019
Amelioration of experimentally induced arthritis by reducing reactive oxygen species production through the intra-articular injection of water-soluble fullerenol
Kuo, W. S., Weng, C-T., Chen, J. H., Wu, C-L., Shiau, A-L., Hsieh, J. L., So, E. C., Wu, P-T. & Chen, S. Y., 2019 六月, 於: Nanomaterials. 9, 6, 909.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Anti-inflammatory and antiviral effects of minocycline in enterovirus 71 infections
Liao, Y. T., Wang, S. M. & Chen, S. H., 2019 十月, 於: Biomedicine and Pharmacotherapy. 118, 109271.研究成果: Article › 同行評審
開啟存取12 引文 斯高帕斯（Scopus） -
Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli
Tsai, S. L., Chang, Y. C., Sarvagalla, S., Wang, S., Coumar, M. S. & Cheung, C. H. A., 2019 八月, 於: Protein Expression and Purification. 160, p. 73-83 11 p.研究成果: Article › 同行評審
3 引文 斯高帕斯（Scopus） -
Combination of modified NS1 and NS3 as a novel vaccine strategy against dengue virus infection
Kao, Y. S., Yu, C. Y., Huang, H. J., Tien, S. M., Wang, W. Y., Yang, M., Anderson, R., Yeh, T. M., Lin, Y. S. & Wan, S. W., 2019 十月 1, 於: Journal of Immunology. 203, 7, p. 1909-1917 9 p.研究成果: Article › 同行評審
5 引文 斯高帕斯（Scopus） -
Conditional deletion of CC2D1A reduces hippocampal synaptic plasticity and impairs cognitive function through RAC1 hyperactivation
Yang, C. Y., Yu, T. H., Wen, W. L., Ling, P. & Hsu, K. S., 2019 六月 19, 於: Journal of Neuroscience. 39, 25, p. 4959-4975 17 p.研究成果: Article › 同行評審
7 引文 斯高帕斯（Scopus） -
Curcumin functions as a MEK inhibitor to induce a synthetic lethal effect on KRAS mutant colorectal cancer cells receiving targeted drug regorafenib
Wu, C. S., Wu, S. Y., Chen, H. C., Chu, C. A., Tang, H. H., Liu, H. S., Hong, Y. R., Huang, C. Y. F., Huang, G. C. & Su, C. L., 2019 十二月, 於: Journal of Nutritional Biochemistry. 74, 108227.研究成果: Article › 同行評審
4 引文 斯高帕斯（Scopus） -
Expression of prothymosin α in lung cancer is associated with squamous cell carcinoma and smoking
Kuo, Y. H., Shiau, A. L., Tung, C. L., Su, Y. C., Li, C. F., Su, B. H., Tsao, C. J., Wu, C. L., Feng, Y. H. & Wu, P., 2019 六月, 於: Oncology Letters. 17, 6, p. 5740-5746 7 p.研究成果: Article › 同行評審
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Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling
Ge, J., Remesh, S. G., Hammel, M., Pan, S., Mahan, A. D., Wang, S. & Wang, X., 2019 八月 6, 於: Structure. 27, 8, p. 1296-1307.e5研究成果: Article › 同行評審
1 引文 斯高帕斯（Scopus） -
Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy
Cheng, Y. L., Kuo, C. F., Lu, S. L., Hiroko, O., Wu, Y. N., Hsie, C. L., Nod, T., Wu, S. R., Anderson, R., Lin, C. F., Chen, C. L., Wu, J. J. & Lin, Y. S., 2019, 於: mBio. 10, 5, e02148-19.研究成果: Article › 同行評審
開啟存取6 引文 斯高帕斯（Scopus） -
HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection
Tseng, P. C., Kuo, C. F., Cheng, M. H., Wan, S. W., Lin, C. F., Chang, C. P., Lin, Y. S., Wu, J. J., Huang, C. C. & Chen, C. L., 2019 九月 18, 於: Frontiers in Immunology. 10, 2147.研究成果: Article › 同行評審
開啟存取1 引文 斯高帕斯（Scopus） -
Implantable microneedles with an immune-boosting function for effective intradermal influenza vaccination
Chen, Y. H., Lai, K. Y., Chiu, Y. H., Wu, Y. W., Shiau, A-L. & Chen, M-C., 2019 十月 1, 於: Acta Biomaterialia. 97, p. 230-238 9 p.研究成果: Article › 同行評審
12 引文 斯高帕斯（Scopus） -
Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps
Pu, C. M., Chen, Y. C., Chen, Y. C., Lee, T. L., Peng, Y. S., Chen, S. H., Yen, Y. H., Chien, C. L., Hsieh, J. H. & Chen, Y. L., 2019, 於: Mediators of Inflammation. 2019, 2343867.研究成果: Article › 同行評審
開啟存取4 引文 斯高帕斯（Scopus） -
Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats
Kuthati, Y., Davuluri, V. N. G., Yang, C. P., Chang, H. C., Chang, C. P. & Wong, C. S., 2019, 於: Journal of Pain Research. 12, p. 2473-2485 13 p.研究成果: Article › 同行評審
開啟存取2 引文 斯高帕斯（Scopus） -
Micro-colonization of arsenic-resistant Staphylococcus sp. As-3 on arsenopyrite (FeAsS) drives arsenic mobilization under anoxic sub-surface mimicking conditions
Rathod, J., Jean, J. S., Jiang, W. T., Huang, I. H., Liu, B. H. & Lee, Y. C., 2019 六月 15, 於: Science of the Total Environment. 669, p. 527-539 13 p.研究成果: Article › 同行評審
9 引文 斯高帕斯（Scopus） -
MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway
Chu, C. A., Lee, C. T., Lee, J. C., Wang, Y. W., Huang, C. T., Lan, S. H., Lin, P. C., Lin, B. W., Tian, Y. F., Liu, H. S. & Chow, N. H., 2019 五月, 於: EBioMedicine. 43, p. 270-281 12 p.研究成果: Article › 同行評審
開啟存取22 引文 斯高帕斯（Scopus） -
MST3 is involved in ENaC-mediated hypertension
Lu, T. J., Kan, W. C., Yang, S. S., Jiang, S. T., Wu, S. N., Ling, P., Bao, B. Y., Lin, C. Y., Yang, Z. Y., Weng, Y. P., Chan, C. H. & Lu, T. L., 2019, 於: American Journal of Physiology - Renal Physiology. 317, 1, p. F30-F42研究成果: Article › 同行評審
2 引文 斯高帕斯（Scopus） -
Mutation of the PTCH1 gene predicts recurrence of breast cancer
Wang, C. Y., Chang, Y. C., Kuo, Y. L., Lee, K. T., Chen, P. S., Cheung, C. H. A., Chang, C. P., Phan, N. N., Shen, M. R. & Hsu, H. P., 2019 十一月 8, 於: Scientific reports. 9, 1, 1 p., 16359.研究成果: Article › 同行評審
開啟存取8 引文 斯高帕斯（Scopus）