微生物學科暨微生物及免疫學研究所

研究成果

每年研究成果 1984 1997 1998 2001 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 823 Article
• 25 Review article
• 24 Patent
• 7 Comment/debate
• 10 更多
  • 5 Chapter
  • 2 Conference contribution
  • 1 Editorial
  • 1 Letter
  • 1 Short survey

每年研究成果

每年研究成果

搜尋結果

• 2017

  Galectin-3 inhibits galectin-8/parkin- mediated ubiquitination of group A streptococcus

  Cheng, Y. L., Wu, Y. W., Kuo, C. F., Lu, S. L., Liu, F. T., Anderson, R., Lin, C. F., Liu, Y. L., Wang, W. Y., Chen, Y. D., Zheng, P. X., Wu, J. J. & Lin, Y. S., 2017 7月 1, 於: mBio. 8, 4, e00899-17.

  研究成果: Article › 同行評審

  開啟存取

  • Galectins 100%
  • Streptococcus 74%
  • Endothelial Cells 26%
  • Ubiquitin 24%
  • Epithelial Cells 17%
  23 引文 斯高帕斯（Scopus）

• Honeysuckle aqueous extract and induced let-7a suppress dengue virus type 2 replication and pathogenesis

  Lee, Y. R., Yeh, S. F., Ruan, X. M., Zhang, H., Hsu, S. D., Huang, H. D., Hsieh, C. C., Lin, Y. S., Yeh, T. M., Liu, H. S. & Gan, D. D., 2017 2月 23, 於: Journal of Ethnopharmacology. 198, p. 109-121 13 p.

  研究成果: Article › 同行評審

  • Lonicera 100%
  • MicroRNA 72%
  • Dengue Virus 70%
  • Virus Replication 59%
  • MicroRNAs 33%
  28 引文 斯高帕斯（Scopus）

• IL-6 ameliorates acute lung injury in influenza virus infection

  Yang, M. L., Wang, C. T., Yang, S. J., Leu, C. H., Chen, S. H., Wu, C. L. & Shiau, A. L., 2017 3月 6, 於: Scientific reports. 7, 43829.

  研究成果: Article › 同行評審

  開啟存取

  • Acute Lung Injury 100%
  • Orthomyxoviridae 88%
  • Virus Diseases 64%
  • Human Influenza 53%
  • Lung 47%
  89 引文 斯高帕斯（Scopus）

• Immunization with a streptococcal multipleepitope recombinant protein protects mice against invasive group A streptococcal infection

  Kuo, C. F., Tsao, N., Hsieh, I. C., Lin, Y. S., Wu, J. J. & Hung, Y. T., 2017 3月, 於: PloS one. 12, 3, 0174464.

  研究成果: Article › 同行評審

  開啟存取

  • Streptococcal Infections 100%
  • Recombinant Proteins 74%
  • Immunization 64%
  • streptolysin S 45%
  • erythrogenic toxin 42%
  8 引文 斯高帕斯（Scopus）

• Immunization with recombinant TcdB-encapsulated nanocomplex induces protection against Clostridium difficile challenge in a mouse model

  Liu, Y. W., Chen, Y. H., Chen, J. W., Tsai, P. J. & Huang, I. H., 2017 7月 25, 於: Frontiers in Microbiology. 8, JUL, 1411.

  研究成果: Article › 同行評審

  開啟存取

  • Clostridium Infections 100%
  • Clostridium difficile 94%
  • Immunization 67%
  • Vaccines 59%
  • Chitosan 58%
  14 引文 斯高帕斯（Scopus）

• Interaction of Zap70 and CXCR4 receptor at lamellipodia that determines the directionality during Jurkat T cells chemotaxis

  Wu, C. Y., Tsai, Y. Y., Chen, S. Y., Lin, Y. P., Shin, J. W., Wu, C. C. & Yang, B. C., 2017 10月, 於: Molecular Immunology. 90, p. 245-254 10 p.

  研究成果: Article › 同行評審

  • CXCR4 Receptors 100%
  • Jurkat Cells 87%
  • Pseudopodia 86%
  • Chemotaxis 77%
  • T-Lymphocytes 44%
  4 引文 斯高帕斯（Scopus）

• Knockdown of toll-like receptor 4 signaling pathways ameliorate bone graft rejection in a mouse model of allograft transplantation

  Hsieh, J. L., Shen, P. C., Wu, P. T., Jou, I. M., Wu, C. L., Shiau, A. L., Wang, C. R., Chong, H. E., Chuang, S. H., Peng, J. S. & Chen, S. Y., 2017 4月 10, 於: Scientific reports. 7, 46050.

  研究成果: Article › 同行評審

  開啟存取

  • Toll-Like Receptor 4 100%
  • Allografts 76%
  • Transplantation 66%
  • Bone and Bones 51%
  • Toll-Like Receptors 47%
  14 引文 斯高帕斯（Scopus）

• Lrp, a global regulator, regulates the virulence of Vibrio vulnificus

  Ho, Y. C., Hung, F. R., Weng, C. H., Li, W. T., Chuang, T. H., Liu, T. L., Lin, C. Y., Lo, C. J., Chen, C. L., Chen, J. W., Hashimoto, M. & Hor, L. I., 2017 8月 11, 於: Journal of biomedical science. 24, 1, p. 54 1 p.

  研究成果: Article › 同行評審

  開啟存取

  • Virulence 58%
  • Mutation 56%
  • Cytotoxin 31%
  • Genes 26%
  • Agar 23%
  8 引文 斯高帕斯（Scopus）

• MED28 Regulates Epithelial–Mesenchymal Transition Through NFκB in Human Breast Cancer Cells

  Huang, C. Y., Hsieh, N. T., Li, C. I., Weng, Y. T., Liu, H. S. & Lee, M. F., 2017 6月 1, 於: Journal of Cellular Physiology. 232, 6, p. 1337-1345 9 p.

  研究成果: Article › 同行評審

  • Marker 100%
  • MCF-7 Cells 48%
  • Cadherins 46%
  • Cell Movement 37%
  • Biological Marker 34%
  11 引文 斯高帕斯（Scopus）

• Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway

  Tsai, H. H., Lai, H. Y., Chen, Y. C., Li, C. F., Huang, H. S., Liu, H. S., Tsai, Y. S. & Wang, J. M., 2017, 於: Oncotarget. 8, 8, p. 13832-13845 14 p.

  研究成果: Article › 同行評審

  開啟存取

  • CCAAT-Enhancer-Binding Protein-delta 100%
  • Metformin 62%
  • Hepatocellular Carcinoma 46%
  • AMP-Activated Protein Kinases 29%
  • AMP-activated protein kinase kinase 12%
  47 引文 斯高帕斯（Scopus）

• One-dimensional poly(L-lysine)-block-poly(L-threonine) assemblies exhibit potent anticancer activity by enhancing membranolysis

  Chen, Y. F., Shiau, A. L., Chang, S. J., Fan, N. S., Wang, C. T., Wu, C. L. & Jan, J. S., 2017 6月, 於: Acta Biomaterialia. 55, p. 283-295 13 p.

  研究成果: Article › 同行評審

  • L-Threonine 100%
  • L-Lysine 84%
  • Threonine 77%
  • Lysine 67%
  • Cell death 34%
  18 引文 斯高帕斯（Scopus）

• P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint

  Chen, S. Y., Shiau, A. L., Wu, C. L. & Wang, C. R., 2017, 於: Oncotarget. 8, 70, p. 115413-115419 7 p.

  研究成果: Article › 同行評審

  開啟存取

  • Fibroblasts 100%
  • Joints 95%
  • Peptides 85%
  • Rheumatoid Arthritis 47%
  • Experimental Arthritis 45%
  6 引文 斯高帕斯（Scopus）

• Perceptions of Clostridium difficile infections among infection control professionals in Taiwan

  Hung, Y. P., Lee, J. C., Lin, H. J., Chiu, C. W., Wu, J. L., Liu, H. C., Huang, I. H., Tsai, P. J. & Ko, W. C., 2017 8月, 於: Journal of Microbiology, Immunology and Infection. 50, 4, p. 521-526 6 p.

  研究成果: Article › 同行評審

  開啟存取

  • Clostridium Infections 100%
  • Infection Control 80%
  • Soaps 17%
  • Professional Education 17%
  • Guidelines 17%
  4 引文 斯高帕斯（Scopus）

• Plasma kallistatin in critically ill patients with severe sepsis and septic shock

  Lin, W. C., Chen, C. W., Chao, L., Chao, J. & Lin, Y. S., 2017 5月, 於: PloS one. 12, 5, e0178387.

  研究成果: Article › 同行評審

  開啟存取

  • Septic Shock 56%
  • Critical Illness 50%
  • Sepsis 44%
  • Intensive Care Units 15%
  • Organ Dysfunction Scores 12%
  13 引文 斯高帕斯（Scopus）

• Prevalence and characterization of enterotoxigenic Bacteroides fragilis and toxigenic Clostridium difficile in a Taipei emergency department

  Ji, D. D., Huang, I. H., Lai, C. C., Wu, F. T., Jiang, D. D. S., Hsu, B. M. & Lin, W. C., 2017 2月 1, 於: Journal of Microbiology, Immunology and Infection. 50, 1, p. 83-89 7 p.

  研究成果: Article › 同行評審

  • Bacteroides fragilis 84%
  • Clostridium difficile 75%
  • Hospital Emergency Service 50%
  • Gastroenteritis 42%
  • Clostridium Infections 31%
  10 引文 斯高帕斯（Scopus）

• Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection

  Zainal, N., Chang, C. P., Cheng, Y. L., Wu, Y. W., Anderson, R., Wan, S. W., Chen, C. L., Ho, T. S., Abubakar, S. & Lin, Y. S., 2017 2月 20, 於: Scientific reports. 7, 42998.

  研究成果: Article › 同行評審

  開啟存取

  • Interferon Type I 100%
  • Dengue Virus 99%
  • Resveratrol 98%
  • Interferons 77%
  • Virus Diseases 61%
  38 引文 斯高帕斯（Scopus）

• S100A10 Regulates ULK1 Localization to ER–Mitochondria Contact Sites in IFN-γ-Triggered Autophagy

  Chen, Y. D., Fang, Y. T., Chang, C. P., Lin, C. F., Hsu, L. J., Wu, S. R., Chiu, Y. C., Anderson, R. & Lin, Y. S., 2017 1月 6, 於: Journal of Molecular Biology. 429, 1, p. 142-157 16 p.

  研究成果: Article › 同行評審

  • Autophagosomes 100%
  • Annexin A2 60%
  • Autophagy-Related Proteins 19%
  • High Mobility Group Proteins 19%
  • Annexins 18%
  11 引文 斯高帕斯（Scopus）

• Suppression of interleukin-6 increases enterovirus A71 lethality in mice

  Wang, L. C., Yao, H. W., Chang, C. F., Wang, S. W., Wang, S. M. & Chen, S. H., 2017 12月 12, 於: Journal of biomedical science. 24, 1, 94.

  研究成果: Article › 同行評審

  開啟存取

  • Pentoxifylline 100%
  • Enterovirus 69%
  • Enterovirus Infections 37%
  • Protein 24%
  • Encephalitis 14%
  2 引文 斯高帕斯（Scopus）

• The Helicobacter pylori J99 jhp0106 gene, under the control of the CsrA/RpoN regulatory system, modulates flagella formation and motility

  Kao, C. Y., Chen, J. W., Wang, S., Sheu, B. S. & Wu, J. J., 2017 3月 28, 於: Frontiers in Microbiology. 8, MAR, 483.

  研究成果: Article › 同行評審

  • Helicobacter pylori 78%
  • Glycosyltransferases 35%
  • Sigma Factor 35%
  • Genes 32%
  • RNA-Seq 31%
  9 引文 斯高帕斯（Scopus）

• Therapeutic effects of monoclonal antibody against dengue virus NS1 in a STAT1 knockout mouse model of dengue infection

  Wan, S. W., Chen, P. W., Chen, C. Y., Lai, Y. C., Chu, Y. T., Hung, C. Y., Lee, H., Wu, H. F., Chuang, Y. C., Lin, J., Chang, C. P., Wang, S., Liu, C. C., Ho, T. S., Lin, C. F., Lee, C. K., Wu-Hsieh, B. A., Anderson, R., Yeh, T. M. & Lin, Y. S., 2017 10月 15, 於: Journal of Immunology. 199, 8, p. 2834-2844 11 p.

  研究成果: Article › 同行評審

  開啟存取

  • Dengue Virus 100%
  • Dengue 96%
  • Knockout Mice 77%
  • Therapeutic Uses 69%
  • Monoclonal Antibodies 61%
  36 引文 斯高帕斯（Scopus）

• The role of Lutheran/basal cell adhesion molecule in human bladder carcinogenesis

  Chang, H. Y., Chang, H. M., Wu, T. J., Chaing, C. Y., Tzai, T. S., Cheng, H. L., Raghavaraju, G., Chow, N. H. & Liu, H. S., 2017 8月 26, 於: Journal of biomedical science. 24, 1, 61.

  研究成果: Article › 同行評審

  開啟存取

  • Cell Adhesion Molecules 100%
  • Urinary Bladder 72%
  • Carcinogenesis 69%
  • Cell Adhesion 26%
  • Laminin 22%
  13 引文 斯高帕斯（Scopus）

• Thymidine kinase-negative herpes simplex virus 1 can efficiently establish persistent infection in neural tissues of nude mice

  Huang, C. Y., Yao, H. W., Wang, L. C., Shen, F. H., Hsu, S. M. & Chen, S. H., 2017, 於: Journal of Virology. 91, 4, e01979-16.

  研究成果: Article › 同行評審

  • thymidine kinase 100%
  • Human alphaherpesvirus 1 98%
  • Human Herpesvirus 1 84%
  • Nude Mice 72%
  • nerve tissue 67%
  8 引文 斯高帕斯（Scopus）

• Using gene expression database to uncover biology functions of 1,4-disubstituted 1,2,3-triazole analogues synthesized via a copper (I)-catalyzed reaction

  Su, C. L., Tseng, C. L., Ramesh, C., Liu, H. S., Huang, C. Y. F. & Yao, C. F., 2017, 於: European Journal of Medicinal Chemistry. 132, p. 90-107 18 p.

  研究成果: Article › 同行評審

  • Triazoles 100%
  • N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea 95%
  • 1,2,3-triazole 87%
  • Glycogen Synthase Kinase 3 Inhibitor 67%
  • Hepatocellular Carcinoma 59%
  19 引文 斯高帕斯（Scopus）

• Veillonella catalase protects the growth of Fusobacterium nucleatum in microaerophilic and Streptococcus gordonii-resident environments

  Zhou, P., Li, X., Huang, I. H. & Qi, F., 2017, 於: Applied and environmental microbiology. 83, 19, e01079-17.

  研究成果: Article › 同行評審

  • Streptococcus gordonii 100%
  • Veillonella 97%
  • Fusobacterium nucleatum 90%
  • Catalase 58%
  • catalase 48%
  26 引文 斯高帕斯（Scopus）
• 2016

  Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

  Cheng, Y. L., Lin, Y-S., Chen, C. L., Tsai, T. T., Tsai, C. C., Wu, Y-W., Ou, Y. D., Chu, Y. Y., Wang, J. M., Yu, C. Y. & Lin, C. F., 2016 8月 26, 於: Scientific reports. 6, 32000.

  研究成果: Article › 同行評審

  開啟存取

  • Dengue Virus 100%
  • Phagocytes 88%
  • Virus Diseases 23%
  • PERK kinase 17%
  • Toll-Like Receptor 3 15%
  36 引文 斯高帕斯（Scopus）

• Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p

  Peng, J. S., Chen, S. Y., Wu, C. L., Chong, H. E., Ding, Y. C., Shiau, A. L. & Wang, C. R., 2016 2月 1, 於: Arthritis and Rheumatology. 68, 2, p. 370-381 12 p.

  研究成果: Article › 同行評審

  開啟存取

  • Experimental Arthritis 100%
  • MicroRNAs 71%
  • Fibroblasts 62%
  • Arthritis 46%
  • Rheumatoid Arthritis 43%
  59 引文 斯高帕斯（Scopus）

• A multiplex dot hybridization assay for detection and differentiation of acanthamoeba and herpes keratitis

  Kuo, M. T., Fang, P. C., Yu, H. J., Chao, T. L., Chien, C. C., Chen, S. H., Wang, J. R., Tseng, S. L., Lai, Y. H., Hsiao, C. C. & Chang, T. C., 2016 4月 1, 於: Investigative Ophthalmology and Visual Science. 57, 4, p. 2158-2163 6 p.

  研究成果: Article › 同行評審

  • Acanthamoeba Keratitis 100%
  • Herpetic Keratitis 93%
  • Keratitis 76%
  • Simplexvirus 23%
  • Real-Time Polymerase Chain Reaction 17%
  10 引文 斯高帕斯（Scopus）

• A novel natural tautomeric pair of garcinielliptone FC suppressed nuclear factor κB and induced apoptosis in human colorectal cancer cells

  Won, S. J., Lin, T. Y., Yen, C. H., Tzeng, Y. H., Liu, H. S., Lin, C. N., Yu, C. H., Wu, C. S., Chen, J. T., Chen, Y. T., Huang, C. Y. F. & Su, C. L., 2016 6月 1, 於: Journal of Functional Foods. 24, p. 568-578 11 p.

  研究成果: Article › 同行評審

  • garcinielliptone FC 100%
  • caspases 57%
  • Garcinia subelliptica 43%
  • apoptosis 41%
  • neoplasm cells 40%
  9 引文 斯高帕斯（Scopus）

• Anti-dengue virus nonstructural protein 1 antibodies contribute to platelet phagocytosis by macrophages

  Wan, S. W., Yang, Y. W., Chu, Y. T., Lin, C. F., Chang, C. P., Yeh, T. M., Anderson, R. & Lin, Y-S., 2016, 於: Thrombosis and Haemostasis. 115, 3, p. 646-656 11 p.

  研究成果: Article › 同行評審

  • Dengue Virus 100%
  • Phagocytosis 83%
  • Blood Platelets 65%
  • Macrophages 59%
  • Antibodies 46%
  22 引文 斯高帕斯（Scopus）

• Attenuation of cancer-initiating cells stemness properties by abrogating S100A4 calcium binding ability in head and neck cancers

  Cheng, L. H., Hung, K. F., Huang, T. F., Hsieh, H. P., Wang, S. Y., Huang, C. Y. & Lo, J. F., 2016, 於: Oncotarget. 7, 48, p. 78946-78957 12 p.

  研究成果: Article › 同行評審

  開啟存取

  • S100 Calcium-Binding Protein A4 100%
  • Mutant Proteins 88%
  • Head and Neck Neoplasms 82%
  • Calcium 56%
  • Neoplasms 26%
  6 引文 斯高帕斯（Scopus）

• Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization

  Wu, Y. W., Mettling, C., Wu, S. R., Yu, C. Y., Perng, G. C., Lin, Y. S. & Lin, Y. L., 2016 8月 25, 於: Scientific reports. 6, 32243.

  研究成果: Article › 同行評審

  開啟存取

  • Dengue 100%
  • Neutralizing Antibodies 87%
  • Viral RNA 63%
  • Antibodies 48%
  • Immune Evasion 36%
  40 引文 斯高帕斯（Scopus）

• Conformational sampling and binding site assessment of suppression of tumorigenicity 2 ectodomain

  Yang, C. Y., Delproposto, J., Chinnaswamy, K., Brown, W. C., Wang, S., Stuckey, J. A. & Wang, X., 2016 1月 6, 於: PloS one. 11, 1, e0146522.

  研究成果: Article › 同行評審

  開啟存取

  • crystal structure 75%
  • binding sites 62%
  • Sampling 60%
  • X-ray scattering 59%
  • Binding Sites 56%
  9 引文 斯高帕斯（Scopus）

• Critical role of IL-6 in dendritic cell-induced allergic inflammation of asthma

  Lin, Y. L., Chen, S. H. & Wang, J. Y., 2016 1月 1, 於: Journal of Molecular Medicine. 94, 1, p. 51-59 9 p.

  研究成果: Article › 同行評審

  • Allergen 100%
  • Dermatophagoides pteronyssinus 76%
  • Dendritic Cells 72%
  • Asthma 62%
  • Polarization 59%
  37 引文 斯高帕斯（Scopus）

• Dengue virus nonstructural protein 1-induced antibodies cross-react with human plasminogen and enhance its activation

  Chuang, Y. C., Lin, J., Lin, Y. S., Wang, S. & Yeh, T. M., 2016 2月 1, 於: Journal of Immunology. 196, 3, p. 1218-1226 9 p.

  研究成果: Article › 同行評審

  • Dengue Virus 88%
  • Plasminogen 88%
  • Antibodies 41%
  • Proteins 27%
  • Fibrinolysis 13%
  35 引文 斯高帕斯（Scopus）

• Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy

  Chen, H. R., Chuang, Y. C., Lin, Y. S., Liu, H. S., Liu, C. C., Perng, G. C. & Yeh, T. M., 2016 7月 13, 於: PLoS neglected tropical diseases. 10, 7, e0004828.

  研究成果: Article › 同行評審

  開啟存取

  • Macrophage Migration-Inhibitory Factors 100%
  • Dengue Virus 86%
  • migration 50%
  • Blood Vessels 42%
  • Proteins 26%
  68 引文 斯高帕斯（Scopus）

• Disabled-2 is a negative immune regulator of lipopolysaccharide-stimulated Toll-like receptor 4 internalization and signaling

  Hung, W. S., Ling, P., Cheng, J. C., Chang, S. S. & Tseng, C. P., 2016 10月 17, 於: Scientific reports. 6, 35343.

  研究成果: Article › 同行評審

  開啟存取

  • Toll-Like Receptor 4 100%
  • Lipopolysaccharides 74%
  • Clathrin 53%
  • Macrophages 40%
  • Endocytosis 29%
  14 引文 斯高帕斯（Scopus）

• Egr-1 deficiency protects from renal inflammation and fibrosis

  Ho, L. C., Sung, J. M., Shen, Y. T., Jheng, H. F., Chen, S. H., Tsai, P. J. & Tsai, Y. S., 2016 8月 1, 於: Journal of Molecular Medicine. 94, 8, p. 933-942 10 p.

  研究成果: Article › 同行評審

  • Creatinine 100%
  • Protective 69%
  • Urea 65%
  • Fibrosis 62%
  • Inflammation 49%
  59 引文 斯高帕斯（Scopus）

• Elovl6 is a poor prognostic predictor in breast cancer

  Feng, Y. H., Chen, W. Y., Kuo, Y. H., Tung, C. L., Tsao, C. J., Shiau, A. L. & Wu, C. L., 2016 7月, 於: Oncology Letters. 12, 1, p. 207-212 6 p.

  研究成果: Article › 同行評審

  • Lymph Nodes 44%
  • Obesity 43%
  • Lipogenesis 38%
  • Mastectomy 34%
  • Non-alcoholic Fatty Liver Disease 33%
  26 引文 斯高帕斯（Scopus）

• Epidemiology analysis of streptococcus pyogenes in a hospital in Southern Taiwan by use of the updated emm cluster typing system

  Chiang-Ni, C., Zheng, P. X., Wang, S. Y., Tsai, P. J., Chuang, W. J., Lin, Y. S., Liu, C. C. & Wu, J. J., 2016 1月, 於: Journal of Clinical Microbiology. 54, 1, p. 157-162 6 p.

  研究成果: Article › 同行評審

  開啟存取

  • Streptococcus 83%
  • Epidemiology 64%
  • Molecular Typing 26%
  • Fibrinogen 19%
  • Genes 16%
  6 引文 斯高帕斯（Scopus）

• Evaluation of cellular retinoic acid binding protein 2 gene expression through the retinoic acid pathway by co-incubation of Blastocystis ST-1 with HT29 cells in vitro

  Liao, C. C., Song, E. J., Chang, T. Y., Lin, W. C., Liu, H. S., Chen, L. R., Huang, L. L. H. & Shin, J. W., 2016 5月 1, 於: Parasitology Research. 115, 5, p. 1965-1975 11 p.

  研究成果: Article › 同行評審

  • Blastocystis 97%
  • Retinoic Acid Receptors 79%
  • HT29 Cells 76%
  • binding proteins 53%
  • Proliferating Cell Nuclear Antigen 44%
  2 引文 斯高帕斯（Scopus）

• Exploring the mechanism responsible for cellulase thermostability by structure-guided recombination

  Chang, C. J., Lee, C. C., Chan, Y. T., Trudeau, D. L., Wu, M. H., Tsai, C. H., Yu, S. M., Ho, T. H. D., Wang, A. H. J., Hsiao, C. D., Arnold, F. H. & Chao, Y. C., 2016 3月, 於: PloS one. 11, 3, e0147485.

  研究成果: Article › 同行評審

  開啟存取

  • Cellulases 100%
  • Cellulase 92%
  • Geobacillus 73%
  • Genetic Recombination 61%
  • endo-1,4-beta-glucanase 59%
  30 引文 斯高帕斯（Scopus）

• Expression regulation of polycistronic lee3 genes of enterohaemorrhagic Escherichia coli

  Sun, W. S. W., Chen, J. W., Wu, Y. C., Tsai, H. Y., Kuo, Y. L. & Syu, W. J., 2016 5月, 於: PloS one. 11, 5, e0155578.

  研究成果: Article › 同行評審

  開啟存取

  • enterohemorrhagic Escherichia coli 100%
  • Enterohemorrhagic Escherichia coli 96%
  • translation (genetics) 43%
  • Escherichia coli O157 38%
  • Operon 33%
  6 引文 斯高帕斯（Scopus）

• Galectin-1-induced autophagy facilitates cisplatin resistance of hepatocellular carcinoma

  Su, Y. C., Davuluri, G. V. N., Chen, C. H., Shiau, D. C., Chen, C. C., Chen, C. L., Lin, Y. S. & Chang, C. P., 2016 2月 1, 於: PloS one. 11, 2, e0148408.

  研究成果: Article › 同行評審

  • Galectin 1 100%
  • Hepatocellular Carcinoma 54%
  • thiodigalactoside 13%
  • Galectins 9%
  • Mitophagy 9%
  57 引文 斯高帕斯（Scopus）

• Integrated microfluidic device using a single universal aptamer to detect multiple types of influenza viruses

  Wang, C. H., Chang, C. P. & Lee, G. B., 2016 12月 15, 於: Biosensors and Bioelectronics. 86, p. 247-254 8 p.

  研究成果: Article › 同行評審

  • Lab-On-A-Chip Devices 100%
  • Viruses 85%
  • Microfluidics 76%
  • Orthomyxoviridae 73%
  • Human Influenza 67%
  44 引文 斯高帕斯（Scopus）

• Integrated microfluidic system for rapid detection of influenza H1N1 virus using a sandwich-based aptamer assay

  Tseng, Y. T., Wang, C. H., Chang, C. P. & Lee, G. B., 2016 8月 15, 於: Biosensors and Bioelectronics. 82, p. 105-111 7 p.

  研究成果: Article › 同行評審

  • Microfluidics 94%
  • Viruses 92%
  • Assays 91%
  • Orthomyxoviridae 79%
  • Satellite Viruses 35%
  61 引文 斯高帕斯（Scopus）

• Intraarticular overexpression of Smad7 ameliorates experimental arthritis

  Chen, S. Y., Shiau, A. L., Wu, C. L. & Wang, C. R., 2016 10月 12, 於: Scientific reports. 6, 35163.

  研究成果: Article › 同行評審

  開啟存取

  • Experimental Arthritis 100%
  • Crohn Disease 60%
  • Joints 59%
  • Rheumatoid Arthritis 52%
  • Arthritis 37%
  8 引文 斯高帕斯（Scopus）

• Microglia retard dengue virus-induced acute viral encephalitis

  Tsai, T. T., Chen, C. L., Lin, Y-S., Chang, C. P., Tsai, C. C., Cheng, Y. L., Huang, C. C., Ho, C. J., Lee, Y. C., Lin, L. T., Jhan, M. K. & Lin, C. F., 2016 6月 9, 於: Scientific reports. 6, 27670.

  研究成果: Article › 同行評審

  開啟存取

  • Viral Encephalitis 100%
  • Dengue Virus 82%
  • Microglia 70%
  • Virus Diseases 36%
  • Cytotoxic T-Lymphocytes 21%
  48 引文 斯高帕斯（Scopus）

• Mutation of the enterohemorrhagic escherichia coli core LPS biosynthesis enzyme RfaD confers hypersusceptibility to host intestinal innate immunity in vivo

  Kuo, C. J., Chen, J. W., Chiu, H. C., Teng, C. H., Hsu, T. I., Lu, P. J., Syu, W. J., Wang, S. T., Chou, T. C. & Chen, C. S., 2016 8月 12, 於: Frontiers in Cellular and Infection Microbiology. 6, AUG, 82.

  研究成果: Article › 同行評審

  開啟存取

  • Enterohemorrhagic Escherichia coli 100%
  • Innate Immunity 67%
  • Lipopolysaccharides 62%
  • Mutation 40%
  • Enzymes 39%
  14 引文 斯高帕斯（Scopus）

• Over-expression of prothymosin-α antagonizes TGFβ signalling to promote the development of emphysema

  Su, B. H., Tseng, Y. L., Shieh, G. S., Chen, Y. C., Wu, P., Shiau, A. L. & Wu, C. L., 2016 2月 1, 於: Journal of Pathology. 238, 3, p. 412-422 11 p.

  研究成果: Article › 同行評審

  • Emphysema 100%
  • Transforming Growth Factors 93%
  • Tissue Inhibitor of Metalloproteinase-3 49%
  • Histone Deacetylases 38%
  • Matrix Metalloproteinases 32%
  16 引文 斯高帕斯（Scopus）

• Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation

  Kan, W. C., Lu, T. L., Ling, P., Lee, T. H., Cho, C. Y., Huang, C. Y. F., Jeng, W. Y., Weng, Y. P., Chiang, C. Y., Wu, J. B. & Lu, T. J., 2016 7月 1, 於: Journal of Inorganic Biochemistry. 160, p. 33-39 7 p.

  研究成果: Article › 同行評審

  • 3-tyrosine 99%
  • Tyrosine 56%
  • Phosphotransferases 47%
  • Phosphorylation 42%
  • Protein 25%
  2 引文 斯高帕斯（Scopus）