生理學科暨研究所

2018

Chronic palmitic acid-induced lipotoxicity correlates with defective trafficking of ATP sensitive potassium channels in pancreatic β cells

Ruan, J. S., Lin, J. K., Kuo, Y. Y., Chen, Y. W. & Chen, P. C., 2018 9月, 於: Journal of Nutritional Biochemistry. 59, p. 37-48 12 p.

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11 引文斯高帕斯（Scopus）

Coincidence Detection of Membrane Stretch and Extracellular pH by the Proton-Sensing Receptor OGR1 (GPR68)

Wei, W. C., Bianchi, F., Wang, Y. K., Tang, M. J., Ye, H. & Glitsch, M. D., 2018 12月 3, 於: Current Biology. 28, 23, p. 3815-3823.e4

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49 引文斯高帕斯（Scopus）

Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration

Chao, R. Y., Cheng, C. H., Wu, S. N. & Chen, P. C., 2018 2月, 於: Journal of Neurochemistry. 144, 4, p. 483-497 15 p.

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18 引文斯高帕斯（Scopus）

Differential regulation of tefluthrin and telmisartan on the gating charges of I_Na activation and inactivation as well as on resurgent and persistent I_Na in a pituitary cell line (GH₃)

So, E. C., Wu, S. N., Lo, Y. C. & Su, K., 2018 3月 15, 於: Toxicology Letters. 285, p. 104-112 9 p.

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36 引文斯高帕斯（Scopus）

Dopamine D3 receptor blockade rescues hyper-dopamine activity-induced deficit in novel object recognition memory

Chang, P. K., Yu, L. & Chen, J. C., 2018 5月 1, 於: Neuropharmacology. 133, p. 216-223 8 p.

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17 引文斯高帕斯（Scopus）

Evidence of Decreased Activity in Intermediate-Conductance Calcium-Activated Potassium Channels During Retinoic Acid-Induced Differentiation in Motor Neuron-Like NSC-34 Cells.

Chen, P., 2018 8月, 於: Cellular Physiology and Biochemistry. 48, 6, p. 2374-2388 15 p., 10.1159/000492653.

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19 引文斯高帕斯（Scopus）

Evidence of Decreased Activity in Intermediate-Conductance Calcium-Activated Potassium Channels During Retinoic Acid–Induced Differentiation in Motor Neuron–Like NSC-34 Cells

Chen, P., Ruan, J. & Wu, S., 2018 1月 1, 於: Cellular Physiology and Biochemistry. 48, 6, p. 2374-2388

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Favouring modulation of circulating lipoproteins and lipid loading capacity by direct antiviral agents grazoprevir/elbasvir or ledipasvir/sofosbuvir treatment against chronic HCV infection

Sun, H. Y., Cheng, P. N., Tseng, C. Y., Tsai, W. J., Chiu, Y. C. & Young, K. C., 2018, 於: Gut. 67, 7, p. 1342-1350 9 p.

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35 引文斯高帕斯（Scopus）

FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells

Chang, M. M., Lai, M. S., Hong, S. Y., Pan, B. S., Huang, H., Yang, S. H., Wu, C. C., Sun, H. S., Chuang, J. I., Wang, C. Y. & Huang, B. M., 2018 11月, 於: Cancer Science. 109, 11, p. 3503-3518 16 p.

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35 引文斯高帕斯（Scopus）

Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington's Disease

Yusuf, I. O., Cheng, P. H., Chen, H. M., Chang, Y. F., Chang, C. Y., Yang, H. I., Lin, C. W., Tsai, S. J., Chuang, J. I., Wu, C. C., Huang, B. M., Sun, H. S. & Yang, S. H., 2018 8月 1, 於: Cellular Physiology and Biochemistry. 48, 2, p. 605-617 13 p.

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24 引文斯高帕斯（Scopus）

Ganoderma triterpenoids exert antiatherogenic effects in mice by alleviating disturbed flow-induced oxidative stress and inflammation

Hsu, P. L., Lin, Y. C., Ni, H. & Mo, F. E., 2018, 於: Oxidative Medicine and Cellular Longevity. 2018, 3491703.

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25 引文斯高帕斯（Scopus）

High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice

Tsai, S. F., Wu, H. T., Chen, P. C., Chen, Y. W., Yu, M., Wang, T. F., Wu, S. Y., Tzeng, S. F. & Kuo, Y. M., 2018 12月 1, 於: Brain Research. 1700, p. 66-77 12 p.

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44 引文斯高帕斯（Scopus）

Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin

Ko, J., Isas, J. M., Sabbaugh, A., Yoo, J. H., Pandey, N. K., Chongtham, A., Ladinsky, M., Wu, W. L., Rohweder, H., Weiss, A., Macdonald, D., Munoz-Sanjuan, I., Langen, R., Patterson, P. H. & Khoshnan, A., 2018 7月 1, 於: Human Molecular Genetics. 27, 13, p. 2330-2343 14 p.

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25 引文斯高帕斯（Scopus）

mGluR5 upregulation and the effects of repeated methamphetamine administration and withdrawal on the rewarding efficacy of ketamine and social interaction

Liao, Y. H., Wang, Y. H., Sun, L. H., Deng, W. T., Lee, H. T. & Yu, L., 2018 12月 1, 於: Toxicology and Applied Pharmacology. 360, p. 58-68 11 p.

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10 引文斯高帕斯（Scopus）

Multiple regulatory actions of 2-guanidine-4-methylquinazoline (GMQ), an agonist of acid-sensing ion channel type 3, on ionic currents in pituitary GH₃ cells and in olfactory sensory (Rolf B1.T) neurons

So, E. C., Wang, Y., Yang, L. Q., So, K. H., Lo, Y. C. & Wu, S. N., 2018 5月, 於: Biochemical Pharmacology. 151, p. 79-88 10 p.

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9 引文斯高帕斯（Scopus）

Notch-1 signaling activation and progesterone receptor expression in ectopic lesions of women with endometriosis

Brown, D. M., Lee, H. C., Liu, S., Quick, C. M., Fernandes, L. M., Simmen, F. A., Tsai, S. J. & Simmen, R. C. M., 2018 1月 1, 於: Journal of the Endocrine Society. 2, 7, p. 765-778 14 p.

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22 引文斯高帕斯（Scopus）

Pioglitazone, a PPAR-γ activator, stimulates BK_Ca but suppresses IK_M in hippocampal neurons

Chen, T. S., Lai, M. C., Hung, T. Y., Lin, K. M., Huang, C. W. & Wu, S. N., 2018 8月 29, 於: Frontiers in Pharmacology. 9, AUG, 977.

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15 引文斯高帕斯（Scopus）

Silver nanoparticles have lethal and sublethal adverse effects on development and longevity by inducing ROS-mediated stress responses

Mao, B. H., Chen, Z. Y., Wang, Y. J. & Yan, S. J., 2018 12月 1, 於: Scientific reports. 8, 1, 2445.

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273 引文斯高帕斯（Scopus）

Stimulatory action of telmisartan, an antagonist of angiotensin II receptor, on voltage-gated Na ⁺ current: Experimental and theoretical studies

Chang, T. T., Yang, C. J., Lee, Y. C. & Wu, S. N., 2018, 於: Chinese Journal of Physiology. 61, 1, p. 1-13 13 p.

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6 引文斯高帕斯（Scopus）

Stress Aggravates High-Fat-Diet-Induced Insulin Resistance via a Mechanism That Involves the Amygdala and Is Associated with Changes in Neuroplasticity

Tsai, S., Wu, H., Chen, P., Chen, Y., Yu, M., Tzeng, S., Wu, P., Chen, P. & Kuo, Y., 2018 9月 1, 於: Neuroendocrinology. 107, 2, p. 147-157

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Synergistic effects of psychosocial stress and mild peripheral infection on inducing microglial activation in the hippocampal dentate gyrus and long-lasting deficits in hippocampus-related memory

Tzeng, W. Y., Su, C. C., Sun, L. H., Cherng, C. G. & Yu, L., 2018, 於: Chinese Journal of Physiology. 61, 2, p. 106-117 12 p.

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5 引文斯高帕斯（Scopus）

The comprehensive electrophysiological study of curcuminoids on delayed-rectifier K⁺ currents in insulin-secreting cells

Kuo, P. C., Yang, C. J., Lee, Y. C., Chen, P. C., Liu, Y. C. & Wu, S. N., 2018 1月 15, 於: European Journal of Pharmacology. 819, p. 233-241 9 p.

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18 引文斯高帕斯（Scopus）

The protective role of bacteroides fragilis in a murine model of colitis-associated colorectal cancer

Lee, Y. K., Mehrabian, P., Boyajian, S., Wu, W. L., Selicha, J., Vonderfecht, S. & Mazmanian, S. K., 2018 11月 1, 於: mSphere. 3, 6, 58718.

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103 引文斯高帕斯（Scopus）

Time Series Integrative Analysis of RNA Sequencing and MicroRNA Expression Data Reveals Key Biologic Wound Healing Pathways in Keloid-Prone Individuals

Onoufriadis, A., Hsu, C. K., Ainali, C., Ung, C. Y., Rashidghamat, E., Yang, H. S., Huang, H. Y., Niazi, U., Tziotzios, C., Yang, J. C., Nuamah, R., Tang, M. J., Saxena, A., de Rinaldis, E. & McGrath, J. A., 2018 12月, 於: Journal of Investigative Dermatology. 138, 12, p. 2690-2693 4 p.

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36 引文斯高帕斯（Scopus）

Viral dynamics of persistent hepatitis C virus infection in high-sensitive reporter cells resemble patient's viremia

Tsai, P., Lin, C. C., Sun, H. Y., Lee, J. C., Chang, T. T. & Young, K. C., 2018 8月, 於: Journal of Microbiology, Immunology and Infection. 51, 4, p. 446-455 10 p.

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6 引文斯高帕斯（Scopus）

2017

A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice

Lai, C. W., Chen, H. L., Tu, M. Y., Lin, W. Y., Röhrig, T., Yang, S. H., Lan, Y. W., Chong, K. Y. & Chen, C. M., 2017, 於: Oncotarget. 8, 5, p. 7357-7369 13 p.

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17 引文斯高帕斯（Scopus）

Basolateral amygdalar D₂ receptor activation is required for the companions-exerted suppressive effect on the cocaine conditioning

Tzeng, W. Y., Cherng, C. F. G., Yu, L. & Wang, C. Y., 2017 1月 1, 於: Neurobiology of Learning and Memory. 137, p. 48-55 8 p.

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4 引文斯高帕斯（Scopus）

CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions

Lai, H. Y., Hsu, L. W., Tsai, H. H., Lo, Y. C., Yang, S. H., Liu, P. Y. & Wang, J. M., 2017 9月 1, 於: Cardiovascular Research. 113, 11, p. 1376-1388 13 p.

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30 引文斯高帕斯（Scopus）

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

Chan, K. Y., Jang, M. J., Yoo, B. B., Greenbaum, A., Ravi, N., Wu, W. L., Sánchez-Guardado, L., Lois, C., Mazmanian, S. K., Deverman, B. E. & Gradinaru, V., 2017 8月 1, 於: Nature Neuroscience. 20, 8, p. 1172-1179 8 p.

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934 引文斯高帕斯（Scopus）

Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress

Wu, C. Y., Hsu, W. L., Tsai, M. H., Liang, J. L., Lu, J. H., Yen, C. J., Yu, H. S., Noda, M., Lu, C. Y., Chen, C. H., Yan, S. J. & Yoshioka, T., 2017 12月 1, 於: Scientific reports. 7, 1, 3606.

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12 引文斯高帕斯（Scopus）

Important modifications by sugammadex, a modified γ-cyclodextrin, of ion currents in differentiated NSC-34 neuronal cells

Hsu, H. T., Lo, Y. C., Huang, Y. M., Tseng, Y. T. & Wu, S. N., 2017 1月 3, 於: BMC Neuroscience. 18, 1, 6.

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8 引文斯高帕斯（Scopus）

Lipoprotein lipase liberates free fatty acids to inhibit HCV infection and prevent hepatic lipid accumulation

Sun, H. Y., Lin, C. C., Tsai, P. J., Tsai, W. J., Lee, J. C., Tsao, C. W., Cheng, P. N., Wu, I. C., Chiu, Y. C., Chang, T. T. & Young, K. C., 2017 4月 1, 於: Cellular Microbiology. 19, 4, e12673.

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12 引文斯高帕斯（Scopus）

Mechanotransduction of matrix stiffness in regulation of focal adhesion size and number: Reciprocal regulation of caveolin-1 and β1 integrin

Yeh, Y. C., Ling, J. Y., Chen, W. C., Lin, H. H. & Tang, M. J., 2017 12月 1, 於: Scientific reports. 7, 1, 15008.

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119 引文斯高帕斯（Scopus）

miR-196a enhances neuronal morphology through suppressing RANBP10 to provide neuroprotection in Huntington's disease

Her, L. S., Mao, S. H., Chang, C. Y., Cheng, P. H., Chang, Y. F., Yang, H. I., Chen, C. M. & Yang, S. H., 2017, 於: Theranostics. 7, 9, p. 2452-2462 11 p.

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46 引文斯高帕斯（Scopus）

Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase inhibitors in neurons: Potential contribution to HIV-associated neurocognitive disorders

Hung, K. M., Chen, P. C., Hsieh, H. C. & Calkins, M. J., 2017 2月 1, 於: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 2, p. 406-413 8 p.

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22 引文斯高帕斯（Scopus）

NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic Β-cells

Wu, Y., Fortin, D. A., Cochrane, V. A., Chen, P. C. & Shyng, S. L., 2017 9月 15, 於: Journal of Biological Chemistry. 292, 37, p. 15512-15524 13 p.

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31 引文斯高帕斯（Scopus）

PTEN, a negative regulator of PI3K/Akt signaling, sustains brain stem cardiovascular regulation during mevinphos intoxication

Tsai, C. Y., Wu, J. C. C., Fang, C. & Chang, A. Y. W., 2017 9月 1, 於: Neuropharmacology. 123, p. 175-185 11 p.

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26 引文斯高帕斯（Scopus）

Sex differences in stress and group housing effects on the number of newly proliferated cells and neuroblasts in middle-aged dentate gyrus

Tzeng, W. Y., Wu, H. H., Wang, C. Y., Chen, J. C., Yu, L. & Cherng, C. G., 2017 1月 9, 於: Frontiers in Behavioral Neuroscience. 10, 249.

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18 引文斯高帕斯（Scopus）

Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels

Wu, S. N., Chern, J. H., Shen, S., Chen, H. H., Hsu, Y. T., Lee, C. C., Chan, M. H., Lai, M. C. & Shie, F. S., 2017 12月, 於: Journal of Cellular Physiology. 232, 12, p. 3409-3421 13 p.

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38 引文斯高帕斯（Scopus）

Synergistic effects of aerobic exercise and cognitive training on cognition, physiological markers, daily function, and quality of life in stroke survivors with cognitive decline: Study protocol for a randomized controlled trial

Yeh, T. T., Wu, C. Y., Hsieh, Y. W., Chang, K. C., Lee, L. C., Hung, J. W., Lin, K. C., Teng, C. H. & Liao, Y. H., 2017 8月 31, 於: Trials. 18, 1, 405.

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17 引文斯高帕斯（Scopus）

Synergistic inhibition of delayed rectifier K ⁺ and voltage-gated Na ⁺ currents by artemisinin in pituitary tumor (GH ₃ ) cells

So, E. C., Wu, S. N., Wu, P. C., Chen, H. Z. & Yang, C. J., 2017 6月 1, 於: Cellular Physiology and Biochemistry. 41, 5, p. 2053-2066 14 p.

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10 引文斯高帕斯（Scopus）

The placental interleukin-6 signaling controls fetal brain development and behavior

Wu, W. L., Hsiao, E. Y., Yan, Z., Mazmanian, S. K. & Patterson, P. H., 2017 5月 1, 於: Brain, Behavior, and Immunity. 62, p. 11-23 13 p.

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195 引文斯高帕斯（Scopus）

The truncated C-terminal fragment of mutant ATXN3 disrupts mitochondria dynamics in spinocerebellar ataxia type 3 models

Hsu, J. Y., Jhang, Y. L., Cheng, P. H., Chang, Y. F., Mao, S. H., Yang, H. I., Lin, C. W., Chen, C. M. & Yang, S. H., 2017 6月 20, 於: Frontiers in Molecular Neuroscience. 10, 196.

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37 引文斯高帕斯（Scopus）

Vagal nerve endings in visceral pleura and triangular ligaments of the rat lung

Wang, F. B., Liao, Y. H. & Wang, Y. C., 2017 2月 1, 於: Journal of Anatomy. 230, 2, p. 303-314 12 p.

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6 引文斯高帕斯（Scopus）

Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages

Chen, C. L., Chien, S. C., Leu, T. H., Harn, H. I. C., Tang, M. J. & Hor, L. I., 2017 8月 19, 於: Journal of biomedical science. 24, 1, 58.

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20 引文斯高帕斯（Scopus）

Whether CD44 is an applicable marker for glioma stem cells

Wang, H. H., Liao, C. C., Chow, N. H., Huang, L. L. H., Chuang, J. I., Wei, K. C. & Shin, J. W., 2017, 於: American Journal of Translational Research. 9, 11, p. 4785-4806 22 p., AJTR0052194.

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29 引文斯高帕斯（Scopus）

2016

Altered mitochondrial dynamics and response to insulin in cybrid cells harboring a diabetes-susceptible mitochondrial DNA haplogroup

Kuo, H. M., Weng, S. W., Chang, A. Y. W., Huang, H. T., Lin, H. Y., Chuang, J. H., Lin, T. K., Liou, C. W., Tai, M. H., Lin, C. Y. & Wang, P. W., 2016 7月 1, 於: Free Radical Biology and Medicine. 96, p. 116-129 14 p.

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23 引文斯高帕斯（Scopus）

Angiotensin II type I receptor (AT1R) is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation

Li, S. H., Lu, H. I., Chang, A. Y. W., Huang, W. T., Lin, W. C., Lee, C. C., Tien, W. Y., Lan, Y. C., Tsai, H. T. & Chen, C. H., 2016, 於: Oncotarget. 7, 41, p. 67150-67165 16 p.

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38 引文斯高帕斯（Scopus）

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

Deverman, B. E., Pravdo, P. L., Simpson, B. P., Kumar, S. R., Chan, K. Y., Banerjee, A., Wu, W. L., Yang, B., Huber, N., Pasca, S. P. & Gradinaru, V., 2016 2月 1, 於: Nature Biotechnology. 34, 2, p. 204-209 6 p.

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749 引文斯高帕斯（Scopus）

DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis

Chen, H. R., Yeh, Y. C., Liu, C. Y., Wu, Y. T., Lo, F. Y., Tang, M. J. & Wang, Y. K., 2016 11月 8, 於: Scientific reports. 6, 36336.

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19 引文斯高帕斯（Scopus）

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