臨床醫學研究所

研究成果 1986 2019

篩選
Article
1 引文 (Scopus)
Systemic Lupus Erythematosus
Non-Hodgkin's Lymphoma
Population
Incidence
Taiwan
1 引文 (Scopus)

Comparison of Home and Ambulatory Blood Pressure Measurements in Association With Preclinical Hypertensive Cardiovascular Damage

Lin, T. T., Juang, J. J. M., Lee, J. K., Tsai, C. T., Chen, C. H., Yu, W. C., Cheng, H. M., Wu, Y. W., Chiu, Y. W., Kuo, C. T., Chen, J. J., Chen, Z. C., Chang, W. T., Liu, P-Y., Chen, P-W., Yen, H. W., Chen, Y. C., Tseng, W. K., Chiang, F. T. & Wu, C. K., 2019 三月 1, 於 : Journal of Cardiovascular Nursing. 34, 2, p. 106-114 9 p.

研究成果: Article

Ambulatory Blood Pressure Monitoring
Blood Pressure
Pulse Wave Analysis
Hypertension
Prehypertension
1 引文 (Scopus)
ivabradine
Neurons
linopirdine
Endocrine Cells
Reducing Agents
Postal Service
Taiwan
Nursing
Medicine
Neoplasms
開啟存取
pioglitazone
Diet
Hepatic Stellate Cells
Insulin Resistance
Autophagy
開啟存取
Galectin 3
rho-Associated Kinases
Medical problems
Platelets
Protein Kinases

Erythropoietin prevents dementia in hemodialysis patients: A nationwide population-based study

Hung, P. H., Yeh, C. C., Sung, F. C., Hsiao, C. Y., Muo, C. H., Hung, K. Y. & Tsai, K-J., 2019 九月 1, 於 : Aging. 11, 17, p. 6941-6950 10 p.

研究成果: Article

Erythropoietin
Dementia
Renal Dialysis
Population
Vascular Dementia

Exercise alleviates osteoporosis in rats with mild chronic kidney disease by decreasing sclerostin production

Liao, H. W., Huang, T-H., Chang, Y. H., Liou, H. H., Chou, Y. H., Sue, Y. M., Hung, P. H., Chang, Y-T., Ho, P. C. & Tsai, K-J., 2019 四月 2, 於 : International journal of molecular sciences. 20, 8, 2044.

研究成果: Article

開啟存取
kidney diseases
osteoporosis
physical exercise
Chronic Renal Insufficiency
bones
開啟存取
Chemotherapy
Teratoma
Surgery
surgery
Drug Therapy

High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma

Lin, C. H., Li, H. Y., Liu, Y. P., Kuo, P. F., Wang, W. C., Lin, F. C., Chang, W. L., Sheu, B. S., Wang, Y. C., Hung, W. C., Cheng, H. C., Yao, Y. C., Calkins, M. J., Hsiao, M. & Lu, P. J., 2019 一月 1, 於 : Therapeutic Advances in Medical Oncology. 11

研究成果: Article

開啟存取
Stem Cells
Fursultiamin
Neoplasms
Therapeutics
Neoplastic Stem Cells
2 引文 (Scopus)

Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology

Hung, P. F., Hong, T-M., Chang, C. C., Hung, C. L., Hsu, Y. L., Chang, Y. L., Wu, C. T., Chang, G. C., Chan, N. L., Yu, S. L., Yang, P. C. & Pan, S. H., 2019 一月 6, 於 : Journal of Experimental and Clinical Cancer Research. 38, 1, 5.

研究成果: Article

開啟存取
Sumoylation
Gastropoda
Biological Science Disciplines
Biochemistry
Cell Biology

IL-29 promoted obesity-induced inflammation and insulin resistance

Lin, T. Y., Chiu, C. J., Kuan, C. H., Chen, F. H., Shen, Y. C., Wu, C-H. & Hsu, Y-H., 2019 一月 1, 於 : Cellular and Molecular Immunology.

研究成果: Article

Interleukins
Insulin Resistance
Obesity
Inflammation
Macrophages
開啟存取
cardiac arrest
rating scales
Heart Arrest
Retrospective Studies
Emergency rooms

Increased ILC3s associated with higher levels of IL‐1β aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase

Chan, T., Yen, C., Huang, Y., Lo, P., Nigrovic, P. A., Cheng, C., Wang, W., Wu, S. & Shieh, C-C., 2019 七月 26, 於 : European Journal of Immunology.

研究成果: Article

1 引文 (Scopus)

Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer

Weng, C. C., Hsieh, M. J., Wu, C. C., Lin, Y. C., Shan, Y-S., Hung, W. C., Chen, L. T. & Cheng, K. H., 2019 五月 20, 於 : Molecular cancer. 18, 1, 96.

研究成果: Article

開啟存取
Pancreatic Neoplasms
Adenocarcinoma
Epithelial-Mesenchymal Transition
Neoplasm Metastasis
Epigenomics
1 引文 (Scopus)
開啟存取
Death Domain Receptors
Neoplastic Stem Cells
Pancreatic Neoplasms
Ligands
T-Lymphocytes

Male patients on peritoneal dialysis have a higher risk of sleep apnea

Lee, Y. C., Hung, S. Y., Wang, H. K., Lin, C. W., Wang, H. H., Chang, M. Y., Wu, C. F., Sung, J-M., Chiou, Y-Y. & Lin, S-H., 2019 一月 1, 於 : Journal of Clinical Sleep Medicine. 15, 7, p. 937-945 9 p.

研究成果: Article

Sleep Apnea Syndromes
Peritoneal Dialysis
Renal Dialysis
Uremia
Databases

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors

Hsueh, Y. S., Chang, H. H., Shan, Y. S., Sun, H. S., Fletcher, J. A., Li, C. F. & Chen, L. T., 2019 九月 19, 於 : Oncogene. 38, 38, p. 6550-6565 16 p.

研究成果: Article

開啟存取
Gastrointestinal Stromal Tumors
Stromal Cells
Chromatin Immunoprecipitation
Valproic Acid
Carcinogenesis

Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8

Wang, H. C., Lin, Y. L., Hsu, C. C., Chao, Y. J., Hou, Y. C., Chiu, T. J., Huang, P. H., Tang, M. J., Chen, L. T. & Shan, Y. S., 2019 一月 1, 於 : Theranostics. 9, 24, p. 7168-7183 16 p.

研究成果: Article

開啟存取
Pancreatic Stellate Cells
Plasminogen Activator Inhibitor 1
Interleukin-8
Pancreatic Neoplasms
Up-Regulation

Postoperative Mycobacteroides abscessus subsp. abscessus endophthalmitis: Clinical analysis of 12 clustered adults and a proposed therapeutic algorithm

Hung, J-H., Ko, W-C., Chen, C. Y., Lin, S-H., Wu, C. L., Hsu, S-M., Teng, Y. T., Wang, S. H., Tseng, S. H., Huang, F-C., Lai, C. C., Chen, C. L., Lai, C. H., Chen, P-L. & Jou-Chen Huang, E., 2019 一月 1, (Accepted/In press) 於 : Journal of Microbiology, Immunology and Infection.

研究成果: Article

Endophthalmitis
Temazepam
Vitrectomy
Taiwan
Nontuberculous Mycobacteria
開啟存取
Venous Thrombosis
Postpartum Period
Catheters
Iliac Vein
Femoral Vein
3 引文 (Scopus)

Protein arginine methyltransferase 3 enhances chemoresistance in pancreatic cancer by methylating hnRNPA1 to increase ABCG2 expression

Hsu, M. C., Pan, M. R., Chu, P. Y., Tsai, Y. L., Tsai, C. H., Shan, Y-S., Chen, L. T. & Hung, W. C., 2019 一月 1, 於 : Cancers. 11, 1, 8.

研究成果: Article

開啟存取
Protein-Arginine N-Methyltransferases
Pancreatic Neoplasms
gemcitabine
Adenosine Triphosphate
Drug Resistance

Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer

Hsu, M. C., Tsai, Y. L., Lin, C. H., Pan, M. R., Shan, Y-S., Cheng, T. Y., Cheng, S. H. C., Chen, L. T. & Hung, W. C., 2019 七月 19, 於 : Journal of Hematology and Oncology. 12, 1, 79.

研究成果: Article

開啟存取
Protein-Arginine N-Methyltransferases
Glyceraldehyde-3-Phosphate Dehydrogenases
Pancreatic Neoplasms
Respiration
Oxidative Phosphorylation

Regeneration of rete ridges in Lanyu pig (Sus scrofa): Insights for human skin wound healing

Lin, C. H., Chiu, P. Y., Hsueh, Y-Y., Shieh, S-J., Wu, C-C., Wong, T-W., Chuong, C. M. & Hughes, M. W., 2019 四月 1, 於 : Experimental Dermatology. 28, 4, p. 472-479 8 p.

研究成果: Article

Sus scrofa
Proliferating Cell Nuclear Antigen
Wound Healing
Alkaline Phosphatase
Regeneration
Metaplasia
Helicobacter pylori
Stomach Neoplasms
MicroRNAs
spasmolytic polypeptide

Subsequent thyroid disorders associated with treatment strategy in head and neck cancer patients: A nationwide cohort study

Lin, C. L., Wu, S-Y., Huang, W. T., Feng, Y. H., Yiu, C. Y., Chiang, W. F., Ho, S. Y. & Lin, S-H., 2019 五月 16, 於 : BMC cancer. 19, 1, 461.

研究成果: Article

開啟存取
Head and Neck Neoplasms
Thyroid Gland
Cohort Studies
Radiotherapy
Neoplasms

Targeted delivery of curcumin rescues endoplasmic reticulum-retained mutant Nox2 protein and avoids leukocyte apoptosis

Yen, C. L., Liao, Y. C., Chen, R. F., Huang, Y. F., Chung, W. C., Lo, P. C., Chang, C-F., Wu, P-C., Shieh, D-B., Jiang, S. T. & Shieh, C-C., 2019 六月 15, 於 : Journal of Immunology. 202, 12, p. 3394-3403 10 p.

研究成果: Article

Curcumin
Mutant Proteins
Endoplasmic Reticulum
Leukocytes
Apoptosis
1 引文 (Scopus)

The dual PI3K/mTOR inhibitor BEZ235 restricts the growth of lung cancer tumors regardless of EGFR status, as a potent accompanist in combined therapeutic regimens

Wu, Y. Y., Wu, H. C., Wu, J. E., Huang, K. Y., Yang, S. C., Chen, S. X., Tsao, C. J., Hsu, K-F., Chen, Y. L. & Hong, T-M., 2019 七月 1, 於 : Journal of Experimental and Clinical Cancer Research. 38, 1, 282.

研究成果: Article

開啟存取
1-Phosphatidylinositol 4-Kinase
Sirolimus
Epidermal Growth Factor Receptor
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Nucleic Acids
Alzheimer Disease
Biomarkers
Amyloid
Relapsing-Remitting Multiple Sclerosis
Aortic Valve Stenosis
Hypertrophic Cardiomyopathy
Myocardium
Heart Ventricles
Hemodynamics
2 引文 (Scopus)

β-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer

Kuo, T. L., Cheng, K. H., Shan, Y-S., Chen, L. T. & Hung, W. C., 2019 一月 1, 於 : Theranostics. 9, 2, p. 324-336 13 p.

研究成果: Article

開啟存取
Catenins
Platelet-Derived Growth Factor
Pancreatic Neoplasms
Neoplasms
Mutation
2018
5 引文 (Scopus)

2018 consensus of the Taiwan Society of Cardiology and the Diabetes Association of Republic of China (Taiwan) on the pharmacological management of patients with type 2 diabetes and cardiovascular diseases

Chiang, C. E., Lin, S. Y., Lin, T. H., Wang, T. D., Yeh, H. I., Chen, J. F., Tsai, C. T., Hung, Y. J., Li, Y-H., Liu, P-Y., Chang, K. C., Wang, K. L., Chao, T-H., Shyu, K. G., Yang, W. S., Ueng, K. C., Chu, P. H., Yin, W. H., Wu, Y. W., Cheng, H. M. 及其他7, Shin, S. J., Huang, C. N., Chuang, L. M., Lin, S. J., Yeh, S. J., Sheu, W. H. H. & Lin, J. L., 2018 三月 1, 於 : Journal of the Chinese Medical Association. 81, 3, p. 189-222 34 p.

研究成果: Article

Cardiology
Taiwan
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Pharmacology
8 引文 (Scopus)

A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancer

Wang, P. S., Chou, C. H., Lin, C. H., Yao, Y. C., Cheng, H. C., Li, H. Y., Chuang, Y. C., Yang, C. N., Ger, L. P., Chen, Y. C., Lin, F-C., Shen, T. L., Hsiao, M. & Lu, P-J., 2018 八月 23, 於 : Oncogene. 37, 34, p. 4662-4678 17 p.

研究成果: Article

Long Noncoding RNA
Triple Negative Breast Neoplasms
Neoplasm Metastasis
Lung
Nucleotides
1 引文 (Scopus)
Interleukin-7 Receptors
Exome
Severe Combined Immunodeficiency
Newborn Infant
Mutation

A pilot-study to assess the feasibility and acceptability of an Internet-based cognitive-behavior group therapy using video conference for patients with coronary artery heart disease

Lin, T. K., Yu, P. T., Lin, L. Y., Liu, P-Y., Li, Y. D., Hsu, C. T., Cheng, Y. R., Yeh, C. Y., Wong, S. S., Pai, S. A., Shee, H. L. & Weng, C. Y., 2018 十一月 1, 於 : PloS one. 13, 11, e0207931.

研究成果: Article

group behavior
heart diseases
Cognitive Therapy
coronary vessels
Group Psychotherapy
2 引文 (Scopus)
Chronic Obstructive Pulmonary Disease
Mortality
Forced Expiratory Volume
Outpatients
Population
Thymoma
Survival
Clone Cells
Histology
Multivariate Analysis
4 引文 (Scopus)

Fucoidan inhibits radiation-induced pneumonitis and lung fibrosis by reducing inflammatory cytokine expression in lung tissues

Yu, H. H., Chengchuan, E. K. O., Chang, C. L., Yuan, K. S. P., Wu, A. T. H., Shan, Y-S. & Wu, S. Y., 2018 十月 19, 於 : Marine Drugs. 16, 10, 392.

研究成果: Article

Radiation Pneumonitis
Fibrosis
Cytokines
Lung
Radiotherapy
Oral Submucous Fibrosis
Oncogenes
Fibroblasts
Growth
Conditioned Culture Medium
Peritoneal Dialysis
Peritonitis
Staphylococcus
Taiwan
Staphylococcal Infections

Is Partial or Total Thyroidectomy Associated with Risk of Long-Term Osteoporosis: A Nationwide Population-Based Study

Hung, C-L., Yeh, C. C., Sung, P-S., Hung, C-J., Muo, C. H., Sung, F. C., Jou, I. M. & Tsai, K-J., 2018 九月 1, 於 : World Journal of Surgery. 42, 9, p. 2864-2871 8 p.

研究成果: Article

Thyroidectomy
Osteoporosis
Osteoporotic Fractures
Population
Thyroxine
5 引文 (Scopus)

Is there different risk of cancer among end-stage renal disease patients undergoing hemodialysis and peritoneal dialysis?

Lee, Y. C., Hung, S. Y., Wang, H. K., Lin, C. W., Wang, H. H., Chang, M. Y., Sung, J-M., Chiou, Y-Y. & Lin, S-H., 2018 二月 1, 於 : Cancer medicine. 7, 2, p. 485-498 14 p.

研究成果: Article

Peritoneal Dialysis
Chronic Kidney Failure
Renal Dialysis
Dialysis
Neoplasms
1 引文 (Scopus)
Laparoscopy
Segmental Mastectomy
Safety
Liver
Neoplasms
2 引文 (Scopus)

Leukoaraiosis and risk of intracranial hemorrhage and outcome after stroke thrombolysis

Yang, C. M., Hung, C-L., Su, H-C., Lin, H. J., Chen, C-H., Lin, C-C., Hu, H. H., Lin, S-H. & Sung, P-S., 2018 五月 1, 於 : PloS one. 13, 5, e0196505.

研究成果: Article

Leukoaraiosis
Intracranial Hemorrhages
stroke
hemorrhage
Brain
3 引文 (Scopus)

Longitudinal neuropsychological outcome in Taiwanese Alzheimer's disease patients treated with medication

Yang, Y. H., Wu, M. N., Chou, P. S., Su, H-C., Lin, S-H. & Sung, P-S., 2018 一月 1, 於 : Current Alzheimer research. 15, 5, p. 474-481 8 p.

研究成果: Article

Dementia
Alzheimer Disease
Neuropsychological Tests
Aptitude
Cholinesterase Inhibitors
1 引文 (Scopus)
Eyelids
ROC Curve
Area Under Curve
Endophenotypes
Sensitivity and Specificity
2 引文 (Scopus)

miRNA-34c overexpression causes dendritic loss and memory decline

Kao, Y. C., Wang, I. F. & Tsai, K. J., 2018 八月 8, 於 : International journal of molecular sciences. 19, 8, 2323.

研究成果: Article

Dendritic Spines
spine
Memory Disorders
Dendrites
MicroRNAs