分子醫學研究所

研究成果

每年研究成果 1985 2006 2008 2010 2012 2013 2014 2015 2016 2018 2020 2024

• 611 Article
• 26 Review article
• 17 Patent
• 15 Comment/debate
• 20 更多
  • 5 Conference contribution
  • 3 Chapter
  • 3 Letter
  • 3 Short survey
  • 2 Conference article
  • 2 Editorial
  • 1 Book
  • 1 Other report

每年研究成果

每年研究成果

搜尋結果

• 2007

  Gypenosides induce apoptosis in human hepatoma Huh-7 cells through a calcium/reactive oxygen species-dependent mitochondrial pathway

  Wang, Q. F., Chiang, C. W., Wu, C. C., Cheng, C. C., Hsieh, S. J., Chen, J. C., Hsieh, Y. C. & Hsu, S. L., 2007 1月 1, 於: Planta Medica. 73, 6, p. 535-544 10 p.

  研究成果: Article › 同行評審

  • gypenoside 100%
  • Reactive Oxygen Metabolite 52%
  • Membrane Potential 48%
  • Hepatocellular Carcinoma 45%
  • Reactive Oxygen Species 44%
  38 引文 斯高帕斯（Scopus）

• Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range

  Majumder, P., Raychaudhuri, S., Chattopadhyay, B. & Bhattacharyya, N. P., 2007 12月, 於: Cellular and Molecular Neurobiology. 27, 8, p. 1127-1145 19 p.

  研究成果: Article › 同行評審

  • Exons 55%
  • Caspase 1 26%
  • Caspase 8 25%
  • Huntington Disease 24%
  • Genes 17%
  29 引文 斯高帕斯（Scopus）

• Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo

  Majumder, P., Chattopadhyay, B., Sukanya, S., Ray, T., Banerjee, M., Mukhopadhyay, D. & Bhattacharyya, N. P., 2007 2月 2, 於: Biochemical and Biophysical Research Communications. 353, 1, p. 80-85 6 p.

  研究成果: Article › 同行評審

  • Caspase 1 100%
  • Fluorescence Quenching 76%
  • In Vitro Techniques 35%
  • HeLa Cells 27%
  • Luciferases 25%
  10 引文 斯高帕斯（Scopus）

• Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes

  Majumder, P., Choudhury, A., Banerjee, M., Lahiri, A. & Bhattacharyya, N. P., 2007 8月, 於: FEBS Journal. 274, 15, p. 3886-3899 14 p.

  研究成果: Article › 同行評審

  • Caspase 10 100%
  • Huntingtin Protein 87%
  • Caspase 1 73%
  • Caspase 8 69%
  • Mutation 50%
  10 引文 斯高帕斯（Scopus）

• Microsatellite in the 3' untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression.

  Chen, T. M., Kuo, P. L., Hsu, C. H., Tsai, S. J., Chen, M. J., Lin, C. W. & Sun, H. S., 2007 1月, 於: Human mutation. 28, 1, p. 98 1 p.

  研究成果: Article › 同行評審

  開啟存取

  • human FGF9 protein 100%
  • Genetic Pleiotropy 72%
  • Microsatellite Repeats 48%
  • 3' Untranslated Regions 47%
  • XY female 46 18%
  30 引文 斯高帕斯（Scopus）

• WW domain-containing oxidoreductase: a candidate tumor suppressor

  Chang, N. S., Hsu, L. J., Lin, Y. S., Lai, F. J. & Sheu, H. M., 2007 1月, 於: Trends in Molecular Medicine. 13, 1, p. 12-22 11 p.

  研究成果: Article › 同行評審

  • WW Domain-Containing Oxidoreductase 100%
  • Hyaluronoglucosaminidase 24%
  • Neoplasms 18%
  • Tumor Protein p73 15%
  • Gonadal Steroid Hormones 10%
  110 引文 斯高帕斯（Scopus）

• Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-κB, JNK1, p53 and WOX1 during stress response

  Hong, Q., Hsu, L. J., Schultz, L., Pratt, N., Mattison, J. & Chang, N. S., 2007 6月 13, 於: BMC Molecular Biology. 8, 50.

  研究成果: Article › 同行評審

  開啟存取

  • Mitogen-Activated Protein Kinase 8 80%
  • Death Domain 75%
  • Cell Death 40%
  • Receptor-Interacting Protein Serine-Threonine Kinases 37%
  • Fas-Associated Death Domain Protein 21%
  42 引文 斯高帕斯（Scopus）
• 2006

  Abundantly expressed genes in pig adipose tissue: An expressed sequence tag approach

  Chen, C. H., Lin, E. C., Cheng, W. T. K., Sun, H. S., Mersmann, H. J. & Ding, S. T., 2006 10月, 於: Journal of animal science. 84, 10, p. 2673-2683 11 p.

  研究成果: Article › 同行評審

  • Expressed Sequence Tags 100%
  • expressed sequence tags 84%
  • adipose tissue 79%
  • Adipose Tissue 66%
  • Swine 62%
  30 引文 斯高帕斯（Scopus）

• Amphiregulin as a tumor promoter for oral squamous cell carcinoma: Involvement of cyclooxygenase 2

  Tsai, S. T., Yang, K. Y., Jin, Y. T., Lin, Y. C., Chang, M. T. & Wu, L. W., 2006 4月, 於: Oral Oncology. 42, 4, p. 381-390 10 p.

  研究成果: Article › 同行評審

  • Amphiregulin 100%
  • Carcinogens 64%
  • Squamous Cell Carcinoma 55%
  • KB Cells 16%
  • Clone Cells 9%
  19 引文 斯高帕斯（Scopus）

• An osteoclastic protein-tyrosine phosphatase is a potential positive regulator of the c-Src protein-tyrosine kinase activity: A mediator of osteoclast activity

  Lau, K. H. W., Wu, L. W., Sheng, M. H. C., Amoui, M., Suhr, S. M. & Baylink, D. J., 2006 4月 1, 於: Journal of Cellular Biochemistry. 97, 5, p. 940-955 16 p.

  研究成果: Article › 同行評審

  • CSK Tyrosine-Protein Kinase 100%
  • Protein Tyrosine Phosphatases 82%
  • Osteoclasts 69%
  • Protein 27%
  • Calcitonin 24%
  28 引文 斯高帕斯（Scopus）

• A Novel Organophosphorus Pesticide Hydrolase Gene Encoded on a Plasmid in Burkholderia sp. Strain NF100

  Tago, K., Yonezawa, S., Ohkouchi, T., Ninomiya, T., Hashimoto, M. & Hayatsu, M., 2006, 於: Microbes and Environments. 21, 1, p. 53-57 5 p.

  研究成果: Article › 同行評審

  開啟存取

  • fenitrothion 100%
  • organophosphorus pesticide 88%
  • organophosphorus pesticides 81%
  • Burkholderia 79%
  • plasmid 76%
  15 引文 斯高帕斯（Scopus）

• Anti-angiogenesis mediated by angiostatin K1-3, K1-4 and K1-4.5. Involvement of p53, FasL, AKT and mRNA deregulation

  Chen, Y. H., Wu, H. L., Li, C., Huang, Y. H., Chiang, C. W., Wu, M. P. & Wu, L. W., 2006 4月, 於: Thrombosis and Haemostasis. 95, 4, p. 668-677 10 p.

  研究成果: Article › 同行評審

  • Angiostatins 100%
  • Messenger RNA 36%
  • Kringles 13%
  • fas Receptor 12%
  • Integrins 8%
  37 引文 斯高帕斯（Scopus）

• Apoptotic effects of over-expressed estrogen receptor-β on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner

  Hsu, H. H., Cheng, S. F., Wu, C. C., Chu, C. H., Weng, Y. J., Lin, C. S., Lee, S. D., Wu, H. C., Huang, C. Y. & Kuo, W. W., 2006, 於: Chinese Journal of Physiology. 49, 2, p. 110-116 7 p.

  研究成果: Article › 同行評審

  • Estrogen Receptors 100%
  • Colonic Neoplasms 96%
  • Colorectal Neoplasms 84%
  • Ligands 75%
  • Down-Regulation 56%
  51 引文 斯高帕斯（Scopus）

• Association of DAZL haplotypes with spermatogenic failure in infertile men

  Teng, Y. N., Lin, Y. M., Sun, H. F. S., Hsu, P. Y., Chung, C. L. & Kuo, P. L., 2006 7月, 於: Fertility and Sterility. 86, 1, p. 129-135 7 p.

  研究成果: Article › 同行評審

  • Haplotypes 100%
  • Single Nucleotide Polymorphism 44%
  • Linkage Disequilibrium 30%
  • Gene Frequency 25%
  • Genotype 19%
  26 引文 斯高帕斯（Scopus）

• Association of NRAMP 1 gene polymorphism with susceptibility to tuberculosis in Taiwanese aboriginals

  Hsu, Y. H., Chen, C. W., Sun, H. S., Jou, R., Lee, J. J. & Su, I. J., 2006 5月, 於: Journal of the Formosan Medical Association. 105, 5, p. 363-369 7 p.

  研究成果: Article › 同行評審

  開啟存取

  • Tuberculosis 100%
  • Genes 48%
  • Microsatellite Repeats 14%
  • 3' Untranslated Regions 14%
  • Genetic Variation 13%
  33 引文 斯高帕斯（Scopus）

• Cardiomyoblast apoptosis induced by insulin-like growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II

  Kuo, W. W., Liu, C. J., Chen, L. M., Wu, C. H., Chu, C. H., Liu, J. Y., Lu, M. C., Lin, J. A., Lee, S. D. & Huang, C. Y., 2006 7月, 於: Apoptosis. 11, 7, p. 1075-1089 15 p.

  研究成果: Article › 同行評審

  • Insulin-Like Growth Factor II 100%
  • Insulin-Like Growth Factor I 94%
  • Angiotensin II 76%
  • Somatomedins 38%
  • Resistance 38%
  35 引文 斯高帕斯（Scopus）

• Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1

  Banerjee, M., Majumder, P., Bhattacharyya, N. P., Dattagupta, J. K. & Sen, U., 2006 12月, 於: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 12, p. 1247-1250 4 p.

  研究成果: Article › 同行評審

  開啟存取

  • Death Effector Domain 100%
  • effectors 87%
  • Huntingtin Protein 83%
  • hot isostatic pressing 70%
  • Crystallization 69%
  1 引文 斯高帕斯（Scopus）

• Cloning and nucleotide sequence of carbaryl hydrolase gene (cahA) from Arthrobacter sp. RC100

  Hashimoto, M., Mizutani, A., Tago, K., Ohnishi-Kameyama, M., Shimojo, T. & Hayatsu, M., 2006 5月, 於: Journal of Bioscience and Bioengineering. 101, 5, p. 410-414 5 p.

  研究成果: Article › 同行評審

  • Hydrolases 100%
  • Carbaryl 72%
  • Cloning 70%
  • Nucleotides 65%
  • Nucleotide Sequence 65%
  40 引文 斯高帕斯（Scopus）

• Computational analysis and refinement of sequence structure on chromosome 22q11.2 region: Application to the development of quantitative real-time PCR assay for clinical diagnosis

  Chen, Y. F., Kou, P. L., Tsai, S. J., Chen, K. F., Chan, H. H., Chen, C. M. & Sun, H. S., 2006 2月, 於: Genomics. 87, 2, p. 290-297 8 p.

  研究成果: Article › 同行評審

  開啟存取

  • Chromosome Structures 100%
  • Genomic Segmental Duplications 70%
  • Sequence Analysis 64%
  • Real-Time Polymerase Chain Reaction 54%
  • Homologous Recombination 52%
  10 引文 斯高帕斯（Scopus）

• CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s

  Gao, C., Li, X., Lam, M., Liu, Y., Chakraborty, S. & Kao, H. Y., 2006 9月 18, 於: FEBS Letters. 580, 21, p. 5096-5104 9 p.

  研究成果: Article › 同行評審

  開啟存取

  • Cell Nucleus Active Transport 100%
  • Cytoplasm 69%
  • Phospho-Specific Antibodies 63%
  • 14-3-3 Proteins 58%
  • Phosphorylation 58%
  28 引文 斯高帕斯（Scopus）

• Cyclooxygenase-2 is involved in S100A2-mediated tumor suppression in squamous cell carcinoma

  Tsai, W. C., Tsai, S. T., Jin, Y. T. & Wu, L. W., 2006 8月, 於: Molecular Cancer Research. 4, 8, p. 539-547 9 p.

  研究成果: Article › 同行評審

  開啟存取

  • Squamous Cell Carcinoma 79%
  • Neoplasms 30%
  • Messenger RNA 18%
  • Ectopic Gene Expression 17%
  • Oligonucleotide Array Sequence Analysis 16%
  44 引文 斯高帕斯（Scopus）

• Effects of ompA deletion on expression of type 1 fimbriae in Escherichia coli K1 strain RS218 and on the association of E. coli with human brain microvascular endothelial cells

  Teng, C. H., Xie, Y., Shin, S., Di Cello, F., Paul-Satyaseela, M., Cai, M. & Kim, K. S., 2006 10月, 於: Infection and Immunity. 74, 10, p. 5609-5616 8 p.

  研究成果: Article › 同行評審

  開啟存取

  • OMPA outer membrane proteins 100%
  • fimbriae 73%
  • outer membrane proteins 72%
  • endothelial cells 63%
  • Endothelial Cells 46%
  58 引文 斯高帕斯（Scopus）

• HbiF regulates type 1 fimbriation independently of FimB and FimE

  Xie, Y., Yao, Y., Kolisnychenko, V., Teng, C. H. & Kim, K. S., 2006 7月, 於: Infection and Immunity. 74, 7, p. 4039-4047 9 p.

  研究成果: Article › 同行評審

  開啟存取

  • Escherichia coli 82%
  • Bacteremia 79%
  • bacteremia 64%
  • Site-specific recombinase 63%
  • recombinases 60%
  41 引文 斯高帕斯（Scopus）

• Identification of medically important yeast species by sequence analysis of the internal transcribed spacer regions

  Leaw, S. N., Chang, H. C., Sun, H. F., Barton, R., Bouchara, J. P. & Chang, T. C., 2006 3月, 於: Journal of Clinical Microbiology. 44, 3, p. 693-699 7 p.

  研究成果: Article › 同行評審

  開啟存取

  • Sequence Analysis 100%
  • Nucleic Acid Databases 94%
  • Yeasts 86%
  • Rhodotorula 84%
  • rRNA Genes 56%
  275 引文 斯高帕斯（Scopus）

• Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1

  Majumder, P., Chattopadhyay, B., Mazumder, A., Das, P. & Bhattacharyya, N. P., 2006 5月, 於: Neurobiology of Disease. 22, 2, p. 242-256 15 p.

  研究成果: Article › 同行評審

  • Huntingtin Protein 100%
  • Caspase 1 67%
  • Caspase 3 48%
  • Caspase 8 47%
  • Apoptosis Inducing Factor 38%
  26 引文 斯高帕斯（Scopus）

• Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation

  Ote, T., Hashimoto, M., Ikeuchi, Y., Su'etsugu, M., Suzuki, T., Katayama, T. & Kato, J. I., 2006 1月, 於: Molecular Microbiology. 59, 1, p. 265-275 11 p.

  研究成果: Article › 同行評審

  開啟存取

  • Folic Acid 100%
  • Carrier Proteins 85%
  • Escherichia coli 70%
  • RNA 70%
  • Transfer RNA 66%
  32 引文 斯高帕斯（Scopus）

• Lithium inhibits ceramide- and etoposide-induced protein phosphatase 2A methylation, Bcl-2 dephosphorylation, caspase-2 activation, and apoptosis

  Chen, C. L., Lin, C. F., Chiang, C. W., Jan, M. S. & Lin, Y. S., 2006, 於: Molecular Pharmacology. 70, 2, p. 510-517 8 p.

  研究成果: Article › 同行評審

  • Protein Phosphatase 2 85%
  • Ceramides 77%
  • Lithium 71%
  • Methylation 59%
  • Okadaic Acid 19%
  60 引文 斯高帕斯（Scopus）

• Over-expressed estrogen receptor-α up-regulates hTNF-α gene expression and down-regulates β-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells

  Hsu, H. H., Cheng, S. F., Chen, L. M., Liu, J. Y., Chu, C. H., Weng, Y. J., Li, Z. Y., Lin, C. S., Lee, S. D., Kuo, W. W. & Huang, C. Y., 2006 9月, 於: Molecular and Cellular Biochemistry. 289, 1-2, p. 101-109 9 p.

  研究成果: Article › 同行評審

  • Catenins 100%
  • Estrogen 84%
  • Estrogen Receptors 74%
  • Colonic Neoplasms 71%
  • DNA Fragmentation 67%
  22 引文 斯高帕斯（Scopus）

• Prostaglandin E₂ induces fibroblast growth factor 9 via EPS-dependent protein kinase Cδ and Elk-1 signaling

  Chuang, P. C., Sun, H. S., Chen, T. M. & Tsai, S. J., 2006 11月, 於: Molecular and Cellular Biology. 26, 22, p. 8281-8292 12 p.

  研究成果: Article › 同行評審

  • Dinoprostone 55%
  • Protein Kinase C 53%
  • human FGF9 protein 17%
  • Stromal Cells 16%
  • ets-Domain Protein Elk-1 14%
  48 引文 斯高帕斯（Scopus）

• Purification and characterization of fenitrothion hydrolase from Burkholderia sp. NF100

  Tago, K., Yonezawa, S., Ohkouchi, T., Hashimoto, M. & Hayatsu, M., 2006 1月, 於: Journal of Bioscience and Bioengineering. 101, 1, p. 80-82 3 p.

  研究成果: Article › 同行評審

  • Hydrolases 100%
  • Fenitrothion 90%
  • Burkholderia 78%
  • Pesticides 72%
  • Organophosphate Pesticide 64%
  19 引文 斯高帕斯（Scopus）

• Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation

  Lee, S. D., Chu, C. H., Huang, E. J., Lu, M. C., Liu, J. Y., Liu, C. J., Hsu, H. H., Lin, J. A., Kuo, W. W. & Huang, C. Y., 2006, 於: American Journal of Physiology - Endocrinology and Metabolism. 291, 2, p. E306-E314

  研究成果: Article › 同行評審

  • Abdominal Aorta 90%
  • Ligation 70%
  • IGF Type 2 Receptor 56%
  • Heart 51%
  • U 0126 28%
  98 引文 斯高帕斯（Scopus）

• α-actinin 4 potentiates myocyte enhancer factor-2 transcription activity by antagonizing histone deacetylase 7

  Chakraborty, S., Reineke, E. L., Lam, M., Li, X., Liu, Y., Gao, C., Khurana, S. & Kao, H. Y., 2006 11月 17, 於: Journal of Biological Chemistry. 281, 46, p. 35070-35080 11 p.

  研究成果: Article › 同行評審

  開啟存取

  • Enhancer 78%
  • Histone Deacetylases 77%
  • Histone 71%
  • Small Interfering RNA 23%
  • Mutation 14%
  65 引文 斯高帕斯（Scopus）
• 2005

  17β-estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: Potential role in cancerous progression of breast and prostate to a premetastatic state in vivo

  Chang, N. S., Schultz, L., Hsu, L. J., Lewis, J., Su, M. & Sze, C. I., 2005 1月 20, 於: Oncogene. 24, 4, p. 714-723 10 p.

  研究成果: Article › 同行評審

  • Prostate 77%
  • Short Chain Dehydrogenase-Reductases 74%
  • Breast 70%
  • Estrogen Receptors 65%
  • Gonadal Steroid Hormones 50%
  77 引文 斯高帕斯（Scopus）

• A functional polymorphism in the promoter region of the tryptophan hydroxylase gene is associated with alcohol dependence in one aboriginal group in Taiwan

  Sun, H. S., Fann, C. S. J., Lane, H. Y., Chang, Y. T., Chang, C. J., Liu, Y. L. & Cheng, A. T. A., 2005 1月, 於: Alcoholism: Clinical and Experimental Research. 29, 1, p. 1-7 7 p.

  研究成果: Article › 同行評審

  • Tryptophan Hydroxylase 100%
  • Genetic Promoter Regions 70%
  • Tryptophan 67%
  • Alcoholism 66%
  • Alcohol 43%
  21 引文 斯高帕斯（Scopus）

• A reference map and identification of porcine testis proteins using 2-DE and MS

  Huang, S. Y., Lin, J. H., Chen, Y. H., Chuang, C. K., Lin, E. C., Huang, M. C., Sun, H. F. S. & Lee, W. C., 2005 11月, 於: Proteomics. 5, 16, p. 4205-4212 8 p.

  研究成果: Article › 同行評審

  • Two Dimensional Polyacrylamide Gel Electrophoresis 100%
  • Testis 75%
  • Swine 67%
  • Protein 35%
  • Proteins 31%
  48 引文 斯高帕斯（Scopus）

• Cell size and nucleoid organization of engineered Escherichia coli cells with a reduced genome

  Hashimoto, M., Ichimura, T., Mizoguchi, H., Tanaka, K., Fujimitsu, K., Keyamura, K., Ote, T., Yamakawa, T., Yamazaki, Y., Mori, H., Katayama, T. & Kato, J. I., 2005 1月, 於: Molecular Microbiology. 55, 1, p. 137-149 13 p.

  研究成果: Article › 同行評審

  開啟存取

  • Cell Size 100%
  • Escherichia coli 68%
  • Genome 66%
  • Chromosomes 30%
  • Genetic Techniques 26%
  224 引文 斯高帕斯（Scopus）

• Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1

  Hsu, L. J., Schultz, L., Mattison, J., Lin, Y. S. & Chang, N. S., 2005 2月 11, 於: Biochemical and Biophysical Research Communications. 327, 2, p. 415-423 9 p.

  研究成果: Article › 同行評審

  • Northern Blotting 89%
  • Saporins 78%
  • Death Domain 75%
  • Zinc Fingers 59%
  • Effector 57%
  14 引文 斯高帕斯（Scopus）

• Escherichia coli K1 RS218 interacts with human brain microvascular endothelial cells via type 1 fimbria bacteria in the fimbriated state

  Teng, C. H., Cai, M., Shin, S., Xie, Y., Kim, K. J., Naveed, A. K., Di Cello, F. & Kwang, S. K., 2005 5月, 於: Infection and Immunity. 73, 5, p. 2923-2931 9 p.

  研究成果: Article › 同行評審

  開啟存取

  • fimbriae 100%
  • endothelial cells 86%
  • Endothelial Cells 62%
  • Escherichia coli 59%
  • brain 58%
  104 引文 斯高帕斯（Scopus）

• FimH adhesin of Escherichia coli K1 type 1 fimbriae activates BV-2 microglia

  Lee, J., Shin, S., Teng, C. H., Suk, J. H. & Kwang, S. K., 2005 9月 2, 於: Biochemical and Biophysical Research Communications. 334, 3, p. 917-923 7 p.

  研究成果: Article › 同行評審

  • Escherichia coli Adhesins 100%
  • Escherichia coli Meningitis 97%
  • Effector 62%
  • Microglia 58%
  • Nitric Oxide 54%
  10 引文 斯高帕斯（Scopus）

• Light-induced retinal damage involves tyrosine 33 phosphorylation, mitochondrial and nuclear translocation of WW domain-containing oxidoreductase in vivo

  Chen, S. T., Chuang, J. I., Cheng, C. L., Hsu, L. J. & Chang, N. S., 2005, 於: Neuroscience. 130, 2, p. 397-407 11 p.

  研究成果: Article › 同行評審

  • WW Domain-Containing Oxidoreductase 100%
  • Tyrosine 52%
  • Retina 49%
  • Light 40%
  • Phosphorylation 39%
  50 引文 斯高帕斯（Scopus）

• Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan

  Lai, T. J., Wu, C. Y., Tsai, H. W., Lin, Y. M. J. & Sun, S., 2005 3月 31, 於: BMC Medical Genetics. 6, 14.

  研究成果: Article › 同行評審

  開啟存取

  • Tryptophan Hydroxylase 100%
  • Mood Disorders 70%
  • Bipolar Disorder 70%
  • Haplotypes 68%
  • Genes 29%
  32 引文 斯高帕斯（Scopus）

• Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer

  Hsu, H. S., Wen, C. K., Tang, Y. A., Lin, R. K., Li, W. Y., Hsu, W. H. & Wang, Y. C., 2005 8月 1, 於: Clinical Cancer Research. 11, 15, p. 5410-5416 7 p.

  研究成果: Article › 同行評審

  • Lung Neoplasms 100%
  • Non-Small Cell Lung Carcinoma 56%
  • Genes 50%
  • Proteins 46%
  • Methylation 38%
  62 引文 斯高帕斯（Scopus）

• S100A2, a potential marker for early recurrence in early-stage oral cancer

  Tsai, S. T., Jin, Y. T., Tsai, W. C., Wang, S. T., Lin, Y. C., Chang, M. T. & Wu, L. W., 2005 4月, 於: Oral Oncology. 41, 4, p. 349-357 9 p.

  研究成果: Article › 同行評審

  • Mouth Neoplasms 100%
  • Tobacco Smoking 15%
  • Mastication 14%
  • Southern Blotting 14%
  • Nuclear Proteins 13%
  29 引文 斯高帕斯（Scopus）

• The profile of cardiac cytochrome c oxidase (COX) expression in an accelerated cardiac-hypertrophy model

  Kuo, W. W., Chu, C. Y., Wu, C. H., Lin, J. A., Liu, J. Y., Ying, T. H., Lee, S. D., Hsieh, Y. H., Chu, C. H., Lin, D. Y., Hsu, H. H. & Huang, C. Y., 2005 7月, 於: Journal of biomedical science. 12, 4, p. 601-610 10 p.

  研究成果: Article › 同行評審

  • Hypertensive 100%
  • Electron Transport Complex IV 84%
  • Cytochrome 62%
  • Ambulatory Surgical Procedures 41%
  • Oxidoreductases 39%
  12 引文 斯高帕斯（Scopus）

• TPMD: A database and resources of microsatellite marker genotyped in Taiwanese populations

  Chang, Y. H., Su, W. H., Lee, T. C., Sunny Sun, H. F., Chen, C. H., Pan, W. H., Tsai, S. F. & Jou, Y. S., 2005 1月 1, 於: Nucleic acids research. 33, DATABASE ISS., p. D174-D177

  研究成果: Article › 同行評審

  開啟存取

  • Microsatellite Repeats 100%
  • Databases 57%
  • Population 37%
  • Human Genome 24%
  • Names 22%
  4 引文 斯高帕斯（Scopus）

• Transcriptional repression of human cad gene by hypoxia inducible factor-1α

  Chen, K. F., Lai, Y. Y., Sun, H. S. & Tsai, S. J., 2005, 於: Nucleic acids research. 33, 16, p. 5190-5198 9 p.

  研究成果: Article › 同行評審

  開啟存取

  • Hypoxia-Inducible Factor 1 100%
  • Hypoxia 62%
  • Response Elements 34%
  • Genes 31%
  • Aspartate Carbamoyltransferase 27%
  69 引文 斯高帕斯（Scopus）

• WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53

  Chang, N. S., Doherty, J., Ensign, A., Schultz, L., Hsu, L. J. & Hong, Q., 2005 12月 30, 於: Journal of Biological Chemistry. 280, 52, p. 43100-43108 9 p.

  研究成果: Article › 同行評審

  開啟存取

  • Cell Death 87%
  • Ultraviolet Rays 84%
  • Serine 79%
  • Tyrosine 75%
  • Phosphorylation 56%
  107 引文 斯高帕斯（Scopus）

• WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo

  Lai, F. J., Cheng, C. L., Chen, S. T., Wu, C. H., Hsu, L. J., Lee, J. Y. Y., Chao, S. C., Sheen, M. C., Shen, C. L., Chang, N. S. & Sheu, H. M., 2005 8月 15, 於: Clinical Cancer Research. 11, 16, p. 5769-5777 9 p.

  研究成果: Article › 同行評審

  • Squamous Cell Carcinoma 100%
  • Skin 65%
  • Phosphorylation 55%
  • human WWOX protein 49%
  • Epidermal Cells 46%
  53 引文 斯高帕斯（Scopus）
• 2004

  An SHIV DNA/MVA rectal vaccination in macaques provides systemic and mucosal virus-specific responses and protection against AIDS

  Wang, S. W., Bertley, F. M. N., Kozlowski, P. A., Herrmann, L., Manson, K., Mazzara, G., Piatak, M., Johnson, R. P., Carville, A., Mansfield, K. & Aldovini, A., 2004 8月, 於: AIDS Research and Human Retroviruses. 20, 8, p. 846-859 14 p.

  研究成果: Article › 同行評審

  • Simian Immunodeficiency Virus 100%
  • Vaccinia virus 93%
  • Macaca 86%
  • Vaccination 62%
  • HIV 53%
  45 引文 斯高帕斯（Scopus）

• Association of tryptophan hydroxylase gene polymorphism with depression, anxiety and comorbid depression and anxiety in a population-based sample of postpartum Taiwanese women

  Sun, H. S., Tsai, H. W., Ko, H. C., Chang, F. M. & Yeh, T. L., 2004 12月, 於: Genes, Brain and Behavior. 3, 6, p. 328-336 9 p.

  研究成果: Article › 同行評審

  • Tryptophan Hydroxylase 100%
  • Postpartum Period 69%
  • Anxiety 52%
  • Depression 47%
  • Haplotypes 39%
  49 引文 斯高帕斯（Scopus）