國際傷口修復與再生中心

研究成果 2004 2019

篩選
Article
2019

A novel zebrafish model to emulate lung injury by folate deficiency-induced swim bladder defectiveness and protease/antiprotease expression imbalance

Lee, G-H., Cheng, N. W., Yu, H. H., Tsai, J. N., Liu, T., Wen, Z. H., Chen, B. H. & Fu, T-F., 2019 十二月 1, 於 : Scientific reports. 9, 1, 12633.

研究成果: Article

開啟存取
Lung Injury
Zebrafish
Protease Inhibitors
Folic Acid
Urinary Bladder
2 引文 (Scopus)
開啟存取
ovaries
Polycystic Ovary Syndrome
Metformin
polymorphism
Polymorphism
開啟存取
Thrombomodulin
Germ Layers
Blastomeres
Organogenesis
Zebrafish
4 引文 (Scopus)

Comparative regenerative biology of spiny (Acomys cahirinus) and laboratory (Mus musculus) mouse skin

Jiang, T. X., Hans, I-C., Ou, K. L., Lei, M. & Chuong, C. M., 2019 四月 1, 於 : Experimental Dermatology. 28, 4, p. 442-449 8 p.

研究成果: Article

Murinae
Hair
Skin
Hair Follicle
Wounds and Injuries

Self-assembly of biological networks via adaptive patterning revealed by avian intradermal muscle network formation

Wu, X. S., Yeh, C. Y., Hans, I-C., Jiang, T. X., Wu, P., Widelitz, R. B., Baker, R. E. & Chuong, C. M., 2019 五月 28, 於 : Proceedings of the National Academy of Sciences of the United States of America. 166, 22, p. 10858-10867 10 p.

研究成果: Article

Muscles
Feathers
Cues
Chickens
Embryonic Structures

Tks5 and dynamin-2 enhance actin bundle rigidity in invadosomes to promote myoblast fusion

Chuang, M. C., Lin, S. S., Ohniwa, R. L., Lee, G. H., Su, Y. A., Chang, Y. C., Tang, M. J. & Liu, Y. W., 2019 五月 1, 於 : Journal of Cell Biology. 218, 5, p. 1670-1685 16 p.

研究成果: Article

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Dynamin II
Myoblasts
Actins
Muscle Development
Actin Cytoskeleton
1 引文 (Scopus)

Turing patterning with and without a global wave

Inaba, M., Harn, H. I. C. & Cheng-Ming, C., 2019 三月, 於 : PLoS biology. 17, 3, e3000195.

研究成果: Article

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Feathers
feathers
Ectodysplasins
Fibroblast Growth Factors
Chickens
2018
10 引文 (Scopus)
Caveolin 1
Keloid
Fibroblasts
Chemical activation
trichostatin A
2017
2 引文 (Scopus)

One crisis, diverse impacts - Tissue-specificity of folate deficiency-induced circulation defects in zebrafish larvae

Tu, H. C., Lee, G. H., Hsiao, T. H., Kao, T. T., Wang, T. Y., Tsai, J. N. & Fu, T. F., 2017 十一月, 於 : PloS one. 12, 11, e0188585.

研究成果: Article

Organ Specificity
Zebrafish
Danio rerio
Folic Acid
folic acid
3 引文 (Scopus)

Revealing the three dimensional architecture of focal adhesion components to explain Ca2 +-mediated turnover of focal adhesions

Chang, S. J., Chen, Y. C., Yang, C. H., Huang, S. C., Huang, H. K., Li, C. C., Harn, H. I. C. & Chiu, W. T., 2017 三月 1, 於 : Biochimica et Biophysica Acta - General Subjects. 1861, 3, p. 624-635 12 p.

研究成果: Article

Focal Adhesions
Adhesion
Calpain
Molecules
Talin

Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser

Wang, S-P., Chang, Y. J., Chi, C. C., Wang, S. H. & Tsai, T. H., 2017 九月 1, 於 : Dermatologica Sinica. 35, 3, p. 119-123 5 p.

研究成果: Article

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Dye Lasers
Hyperplasia
Purpura
Therapeutics
Pain
6 引文 (Scopus)
Vibrio vulnificus
Macrophages
Cytotoxins
Phagocytosis
Focal Adhesion Kinase 2
2016
7 引文 (Scopus)
Gastrointestinal Stromal Tumors
Sequence Deletion
Codon
Exons
Stromal Cells
2 引文 (Scopus)
Elasticity
Actin Cytoskeleton
Focal Adhesions
Atomic Force Microscopy
Research
2015
13 引文 (Scopus)
開啟存取
Caveolin 1
NFATC Transcription Factors
Calcium
Gene Expression
Transcription Factors
14 引文 (Scopus)
Keloid
Elasticity
Fibroblasts
Spatial distribution
Actins
50 引文 (Scopus)

Mechanical phenotype of cancer cells: Cell softening and loss of stiffness sensing

Lin, H. H., Lin, H. K., Lin, I. H., Chiou, Y. W., Chen, H. W., Liu, C. Y., Harn, H. I. C., Chiu, W. T., Wang, Y. K., Shen, M. R. & Tang, M. J., 2015 一月 1, 於 : Oncotarget. 6, 25, p. 20946-20958 13 p.

研究成果: Article

Phenotype
Caveolin 1
Neoplasms
Fibroblasts
Elasticity
17 引文 (Scopus)

Mechanosensitive store-operated calcium entry regulates the formation of cell polarity

Huang, Y. W., Chang, S. J., I-Chen Harn, H., Huang, H. T., Lin, H. H., Shen, M. R., Tang, M. J. & Chiu, W. T., 2015 九月 1, 於 : Journal of Cellular Physiology. 230, 9, p. 2086-2097 12 p.

研究成果: Article

Cell Polarity
Caveolin 1
Cells
Calcium
Polarization
2014
22 引文 (Scopus)

A nanopatterned cell-seeded cardiac patch prevents electro-uncoupling and improves the therapeutic efficacy of cardiac repair

Lin, Y. D., Ko, M. C., Wu, S. T., Li, S. F., Hu, J. F., Lai, Y. J., Harn, H. I. C., Laio, I. C., Yeh, M. L., Yeh, H. I., Tang, M. J., Chang, K. C., Su, F. C., Wei, E. I. H., Lee, S. T., Chen, J. H., Hoffman, A. S., Wu, W. T. & Hsieh, P. C. H., 2014 四月, 於 : Biomaterials Science. 2, 4, p. 567-580 14 p.

研究成果: Article

Endothelial cells
Repair
Anisotropy
Medical nanotechnology
Hemodynamics
28 引文 (Scopus)

Aspartic acid-based modified PLGA-PEG nanoparticles for bone targeting: In vitro and in vivo evaluation

Fu, Y. C., Fu, T. F., Wang, H. J., Lin, C. W., Lee, G. H., Wu, S. C. & Wang, C. K., 2014 十一月 1, 於 : Acta Biomaterialia. 10, 11, p. 4583-4596 14 p.

研究成果: Article

Aspartic Acid
Nanoparticles
Polyethylene glycols
Bone
Bone and Bones
12 引文 (Scopus)

Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress

Hsiao, T. H., Lin, C. J., Chung, Y. S., Lee, G. H., Kao, T. T., Chang, W. N., Chen, B. H., Hung, J. J. & Fu, T. F., 2014 二月 1, 於 : Molecular and Cellular Biology. 34, 3, p. 498-509 12 p.

研究成果: Article

Oxidative Stress
Ethanol
Up-Regulation
Folic Acid
Embryonic Structures
23 引文 (Scopus)
Neural Tube Defects
Zebrafish
Folic Acid
Alzheimer Disease
Oxidative Stress
5 引文 (Scopus)

Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement

Chang, W. N., Lee, G. H., Kao, T. T., Lin, C. Y., Hsiao, T. H., Tsai, J. N., Chen, B. H., Chen, Y. H., Wu, H. R., Tsai, H. J. & Fu, T. F., 2014 一月 1, 於 : Biochimica et Biophysica Acta - General Subjects. 1840, 7, p. 2340-2350 11 p.

研究成果: Article

Oxidative stress
Zebrafish
Embryonic Development
Oxidative Stress
Folic Acid
33 引文 (Scopus)

MiR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation

Huang, H. N., Chen, S. Y., Hwang, S. M., Yu, C. C., Su, M. W., Mai, W., Wang, H. W., Cheng, W. C., Schuyler, S. C., Ma, N., Lu, F. L. & Lu, J., 2014 三月 1, 於 : Stem Cell Research. 12, 2, p. 338-353 16 p.

研究成果: Article

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Cell Differentiation
Carrier Proteins
Embryoid Bodies
Down-Regulation
Endoderm
11 引文 (Scopus)

MTOR inhibition enhances NVP-AUY922-induced autophagymediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors

Hsueh, Y. S., Chang, H. H., Chiang, N. J., Yen, C. C., Li, C. F. & Chen, L. T., 2014 一月 1, 於 : Oncotarget. 5, 22, p. 11711-11724 14 p.

研究成果: Article

Gastrointestinal Stromal Tumors
Sirolimus
Autophagy
Stromal Cells
Proteasome Endopeptidase Complex
23 引文 (Scopus)
Epidermolysis Bullosa
Skin Diseases
Epidermolysis Bullosa Dystrophica
Biomedical Engineering
Pluripotent Stem Cells
2013
18 引文 (Scopus)

Autophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors

Hsueh, Y-S., Yen, C. C., Shih, N. Y., Chiang, N. J., Li, C. F. & Chen, L. T., 2013 一月 1, 於 : Autophagy. 9, 2, p. 220-233 14 p.

研究成果: Article

開啟存取
Gastrointestinal Stromal Tumors
Autophagy
Proteins
Proteasome Endopeptidase Complex
Stromal Cells
25 引文 (Scopus)

Enhancement of renal epithelial cell functions through microfluidic-based coculture with adipose-derived stem cells

Huang, H. C., Chang, Y. J., Chen, W. C., Harn, H. I. C., Tang, M. J. & Wu, C. C., 2013 九月 1, 於 : Tissue Engineering - Part A. 19, 17-18, p. 2024-2034 11 p.

研究成果: Article

Microfluidics
Coculture Techniques
Stem cells
Stem Cells
Collagen
9 引文 (Scopus)

Methotrexate-Induced Decrease in Embryonic 5-Methyl-Tetrahydrofolate Is Irreversible with Leucovorin Supplementation

Kao, T. T., Lee, G. H., Fu, C. C., Chen, B. H., Chen, L. T. & Fu, T. F., 2013 九月 1, 於 : Zebrafish. 10, 3, p. 326-337 12 p.

研究成果: Article

methotrexate
Leucovorin
Folic Acid
Methotrexate
folic acid
13 引文 (Scopus)

Selecting Tyrosine Kinase Inhibitors for Gastrointestinal Stromal Tumor with Secondary KIT Activation-Loop Domain Mutations

Hsueh, Y. S., Lin, C. L., Chiang, N. J., Yen, C. C., Li, C. F., Shan, Y. S., Ko, C. H., Shih, N. Y., Wang, L. M., Chen, T. S. & Chen, L. T., 2013 六月 20, 於 : PloS one. 8, 6, e65762.

研究成果: Article

Gastrointestinal Stromal Tumors
Protein-Tyrosine Kinases
exons
tyrosine
Tumors
20 引文 (Scopus)

The enhancement of biofilm formation in Group B streptococcal isolates at vaginal pH

Ho, Y. R., Li, C. M., Yu, C. H., Lin, Y. J., Wu, C. M., Harn, I. C., Tang, M. J., Chen, Y. T., Shen, F. C., Lu, C. Y., Tsai, T. C. & Wu, J. J., 2013 四月 1, 於 : Medical Microbiology and Immunology. 202, 2, p. 105-115 11 p.

研究成果: Article

Biofilms
Streptococcus agalactiae
Atomic Force Microscopy
Vagina
Pregnant Women
17 引文 (Scopus)

Using surfaces to modulate the morphology and structure of attached cells-a case of cancer cells on chitosan membranes

Shuai, H. H., Yang, C. Y., Hans, I-C., York, R. L., Liao, T. C., Chen, W. S., Yeh, J. A. & Cheng, C. M., 2013 八月 1, 於 : Chemical Science. 4, 8, p. 3058-3067 10 p.

研究成果: Article

Chitosan
Cells
Membranes
Fibroblasts
Cell culture
2012
3 引文 (Scopus)

Comparison of the electromyographic activation level and unilateral selectivity of erector spinae during different selected movements

Guo, L. Y., Wang, Y. L., Huang, Y. H., Yang, C. H., Hou, Y. Y., Hans, I-C. & You, Y. L., 2012 十二月 1, 於 : International Journal of Rehabilitation Research. 35, 4, p. 345-351 7 p.

研究成果: Article

Exercise
Muscle Strength
Scoliosis
Spinal Diseases
Muscles
12 引文 (Scopus)

Zebrafish larvae exposed to ginkgotoxin exhibit seizure like behavior that is relieved by pyridoxal-5′-phosphate, GABA and anti-epileptic drugs

Lee, G. H., Sung, S. Y., Chang, W. N., Kao, T. T., Du, H. C., Hsiao, T. H., Safo, M. K. & Fu, T. F., 2012 十一月 1, 於 : DMM Disease Models and Mechanisms. 5, 6, p. 785-795 11 p.

研究成果: Article

Pyridoxal Phosphate
Zebrafish
gamma-Aminobutyric Acid
Larva
Seizures
2011
22 引文 (Scopus)
Basic Helix-Loop-Helix Transcription Factors
Muscle Development
Zebrafish
Mesoderm
Head
2009
21 引文 (Scopus)

Neuronal Nitric Oxide Synthase Activation Is Involved in Insulin-Mediated Cardiovascular Effects in the Nucleus Tractus Solitarii of Rats

Chiang, H. T., Cheng, W. H., Lu, P. J., Huang, H. N., Lo, W. C., Tseng, Y. C., Wang, J. L., Hsiao, M. & Tseng, C. J., 2009 三月 17, 於 : Neuroscience. 159, 2, p. 727-734 8 p.

研究成果: Article

Nitric Oxide Synthase Type I
Solitary Nucleus
Insulin
Inbred WKY Rats
Microinjections
33 引文 (Scopus)
CCAAT-Binding Factor
Zebrafish
Cartilage
Head
Neural Crest
2008
7 引文 (Scopus)

Defective phosphatidylinositol 3-kinase signaling in central control of cardiovascular effects in the nucleus tractus solitarii of spontaneously hypertensive rats

Hsiao, M., Lu, P. J., Huang, H. N., Lo, W. C., Ho, W. Y., Lai, T. C., Chiang, H. T. & Tseng, C. J., 2008 六月 1, 於 : Hypertension Research. 31, 6, p. 1209-1218 10 p.

研究成果: Article

Phosphatidylinositol 3-Kinase
Solitary Nucleus
Inbred SHR Rats
Inbred WKY Rats
Nitric Oxide Synthase
19 引文 (Scopus)

Inactivation of zebrafish mrf4 leads to myofibril misalignment and motor axon growth disorganization

Wang, Y. H., Li, C. K., Lee, G-H., Tsay, H. J., Tsai, H. J. & Chen, Y. H., 2008 四月 1, 於 : Developmental Dynamics. 237, 4, p. 1043-1050 8 p.

研究成果: Article

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Myofibrils
Zebrafish
Axons
Muscles
Growth
2004
37 引文 (Scopus)

In situ Akt phosphorylation in the nucleus tractus solitarii is involved in central control of blood pressure and heart rate

Huang, H. N., Lu, P. J., Lo, W. C., Lin, C. H., Hsiao, M. & Tseng, C. J., 2004 十月 19, 於 : Circulation. 110, 16, p. 2476-2483 8 p.

研究成果: Article

Solitary Nucleus
Heart Rate
Phosphorylation
Insulin
Blood Pressure