Chang-Shi Chen

2023

Isocitrate Dehydrogenase Alpha-1 Modulates Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans

Lin, Z. H., Chang, S. Y., Shen, W. C., Lin, Y. H., Shen, C. L., Liao, S. B., Liu, Y. C., Chen, C. S., Ching, T. T. & Wang, H. D., 2023 1月, 於: International journal of molecular sciences. 24, 1, 612.

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2021

Effects of electrotactic exercise and antioxidant EUK-134 on oxidative stress relief in Caenorhabditis elegans

Pham, T. T. H., Huang, W. Y., Chen, C. S., Chiu, W. T., Han & Chuang, S., 2021 1月, 於: PloS one. 16, 1 January, e0245474.

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1 引文斯高帕斯（Scopus）

Host CDK-1 and formin mediate microvillar effacement induced by enterohemorrhagic Escherichia coli

Huang, C. R., Kuo, C. J., Huang, C. W., Chen, Y. T., Liu, B. Y., Lee, C. T., Chen, P. L., Chang, W. T., Chen, Y. W., Lee, T. M., Hsieh, H. C. & Chen, C. S., 2021 12月, 於: Nature communications. 12, 1, 90.

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3 引文斯高帕斯（Scopus）

Iron acquisition of urinary tract infection escherichia coli involves pathogenicity in caenorhabditis elegans

Hashimoto, M., Ma, Y. F., Wang, S. T., Chen, C. S. & Teng, C. H., 2021 2月, 於: Microorganisms. 9, 2, p. 1-11 11 p., 310.

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2 引文斯高帕斯（Scopus）

OmpR coordinates the expression of virulence factors of Enterohemorrhagic Escherichia coli in the alimentary tract of Caenorhabditis elegans

Wang, S. T., Kuo, C. J., Huang, C. W., Lee, T. M., Chen, J. W. & Chen, C. S., 2021 7月, 於: Molecular Microbiology. 116, 1, p. 168-183 16 p.

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6 引文斯高帕斯（Scopus）

The conserved regulator of autophagy and innate immunity hlh-30/TFEB mediates tolerance of enterohemorrhagic Escherichia coli in Caenorhabditis elegans

Tsai, C. E., Yang, F. J., Lee, C. H., Hsueh, Y. P., Kuo, C. J. & Chen, C. S., 2021 1月, 於: Genetics. 217, 1, iyaa052.

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2020

IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans

Kuo, C. J., Hsu, Y. C., Wang, S. T., Liou, B. Y., Lim, S. B. Y., Chen, Y. W. & Chen, C. S., 2020 11月 30, 於: Frontiers in Immunology. 11, 561337.

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4 引文斯高帕斯（Scopus）

The role of the bacterial protease Prc in the uropathogenesis of extraintestinal pathogenic Escherichia coli

Huang, W. C., Lin, C. Y., Hashimoto, M., Wu, J. J., Wang, M. C., Lin, W. H., Chen, C. S. & Teng, C. H., 2020 1月 3, 於: Journal of biomedical science. 27, 1, 1 p.

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16 引文斯高帕斯（Scopus）

UvrY is required for the full virulence of Aeromonas dhakensis

Chen, Y. W., Yeh, W. H., Tang, H. J., Chen, J. W., Shu, H. Y., Su, Y. C., Wang, S. T., Kuo, C. J., Chuang, Y. C., Chen, C. C., Ko, W. C., Chen, C. S. & Chen, P. L., 2020 1月 1, 於: Virulence. 11, 1, p. 502-520 19 p.

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5 引文斯高帕斯（Scopus）

2019

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

RELISH Consortium, 2019, 於: Database. 2019, p. 1-67 67 p.

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14 引文斯高帕斯（Scopus）

2018

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli

Kuo, C. J., Wang, S. T., Lin, C. M., Chiu, H. C., Huang, C. R., Lee, D. Y., Chang, G. D., Chou, T. C., Chen, J. W. & Chen, C. S., 2018 3月 1, 於: Cell Death and Disease. 9, 3, 381.

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16 引文斯高帕斯（Scopus）

Design and synthesis of malonamide derivatives as antibiotics against methicillin-resistant staphylococcus aureus

Su, J. C., Huang, Y. T., Chen, C. S., Chiu, H. C. & Shiau, C. W., 2018, 於: Molecules. 23, 1, 27.

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6 引文斯高帕斯（Scopus）

Detection of enterohemorrhagic escherichia coli colonization in murine host by non-invasive in vivo bioluminescence system

Kuo, C. J., Wang, S. T. & Chen, C. S., 2018 4月 9, 於: Journal of Visualized Experiments. 2018, 134, e56169.

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2 引文斯高帕斯（Scopus）

Evaluating virulence and pathogenesis of Aeromonas Infection in a Caenorhabditis elegans model

Chen, Y. W., Ko, W. C., Chen, C. S. & Chen, P. L., 2018 12月, 於: Journal of Visualized Experiments. 2018, 142, e58768.

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10 引文斯高帕斯（Scopus）

Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity

Tu, L. H., Tseng, N. H., Tsai, Y. R., Lin, T. W., Lo, Y. W., Charng, J. L., Hsu, H. T., Chen, Y. S., Chen, R. J., Wu, Y. T., Chan, Y. T., Chen, C. S., Fang, J. M. & Chen, Y. R., 2018 10月 5, 於: European Journal of Medicinal Chemistry. 158, p. 393-404 12 p.

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9 引文斯高帕斯（Scopus）

RIOK-1 is a suppressor of the p38 MAPK innate immune pathway in Caenorhabditis elegans

Chen, Y. W., Ko, W. C., Chen, C. S. & Chen, P. L., 2018 4月 17, 於: Frontiers in Immunology. 9, APR, 774.

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12 引文斯高帕斯（Scopus）

2017

A disease model of muscle necrosis caused by aeromonas dhakensis infection in caenorhabditis elegans

Chen, P. L., Chen, Y. W., Ou, C. C., Lee, T. M., Wu, C. J., Ko, W. C. & Chen, C. S., 2017 1月 4, 於: Frontiers in Microbiology. 7, JAN, 2058.

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12 引文斯高帕斯（Scopus）

HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans

Chen, H. D., Kao, C. Y., Liu, B. Y., Huang, S. W., Kuo, C. J., Ruan, J. W., Lin, Y. H., Huang, C. R., Chen, Y. H., Wang, H. D., Aroian, R. V. & Chen, C. S., 2017 2月 1, 於: Autophagy. 13, 2, p. 371-385 15 p.

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34 引文斯高帕斯（Scopus）

Neuroprotective Effects of Betulin in Pharmacological and Transgenic Caenorhabditis elegans Models of Parkinson’s Disease

Tsai, C. W., Tsai, R. T., Liu, S. P., Chen, C. S., Tsai, M. C., Chien, S. H., Hung, H. S., Lin, S. Z., Shyu, W. C. & Fu, R. H., 2017 12月 1, 於: Cell Transplantation. 26, 12, p. 1903-1918 16 p.

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35 引文斯高帕斯（Scopus）

Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells

Huang, H. L., Wu, H. Y., Chu, P. C., Lai, I. L., Huang, P. H., Kulp, S. K., Pan, S. L., Teng, C. M. & Chen, C. S., 2017, 於: Oncogenesis. 6, 7, e359.

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7 引文斯高帕斯（Scopus）

TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1

Huang, P. H., Lu, P. J., Ding, L. Y., Chu, P. C., Hsu, W. Y., Chen, C. S., Tsao, C. C., Chen, B. H., Lee, C. T., Shan, Y. S. & Chen, C. S., 2017 4月 20, 於: Oncogene. 36, 16, p. 2202-2214 13 p.

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23 引文斯高帕斯（Scopus）

2016

Exercise in an electrotactic flow chamber ameliorates age-related degeneration in Caenorhabditis elegans

Chuang, H. S., Kuo, W. J., Lee, C. L., Chu, I. H. & Chen, C. S., 2016 6月 16, 於: Scientific reports. 6, 28064.

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39 引文斯高帕斯（Scopus）

In vitro and in vivo activity of a novel sorafenib derivative SC5005 against MRSA

Chang, H. C., Huang, Y. T., Chen, C. S., Chen, Y. W., Huang, Y. T., Su, J. C., Teng, L. J., Shiau, C. W. & Chiu, H. C., 2016 2月 1, 於: Journal of Antimicrobial Chemotherapy. 71, 2, p. 449-459 11 p., dkv367.

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24 引文斯高帕斯（Scopus）

Mutation of the enterohemorrhagic escherichia coli core LPS biosynthesis enzyme RfaD confers hypersusceptibility to host intestinal innate immunity in vivo

Kuo, C. J., Chen, J. W., Chiu, H. C., Teng, C. H., Hsu, T. I., Lu, P. J., Syu, W. J., Wang, S. T., Chou, T. C. & Chen, C. S., 2016 8月 12, 於: Frontiers in Cellular and Infection Microbiology. 6, AUG, 82.

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15 引文斯高帕斯（Scopus）

2015

Aeromonas stool isolates from individuals with or without diarrhea in southern Taiwan: Predominance of Aeromonas veronii

Chen, P. L., Tsai, P. J., Chen, C. S., Lu, Y. C., Chen, H. M., Lee, N. Y., Lee, C. C., Li, C. W., Li, M. C., Wu, C. J. & Ko, W. C., 2015 12月 1, 於: Journal of Microbiology, Immunology and Infection. 48, 6, p. 618-624 7 p.

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30 引文斯高帕斯（Scopus）

Loss of DNase II function in the gonad is associated with a higher expression of antimicrobial genes in Caenorhabditis elegans

Yu, H., Lai, H. J., Lin, T. W., Chen, C. S. & Lo, S. J., 2015 8月 15, 於: Biochemical Journal. 470, 1, p. 145-154 10 p.

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9 引文斯高帕斯（Scopus）

2014

Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease

Fu, R. H., Wang, Y. C., Chen, C. S., Tsai, R. T., Liu, S. P., Chang, W. L., Lin, H. L., Lu, C. H., Wei, J. R., Wang, Z. W., Shyu, W. C. & Lin, S. Z., 2014 7月, 於: Neuropharmacology. 82, p. 108-120 13 p.

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44 引文斯高帕斯（Scopus）

A comparative study of clinical Aeromonas dhakensis and Aeromonas hydrophila isolates in southern Taiwan: A. dhakensis is more predominant and virulent

Chen, P. L., Wu, C. J., Chen, C. S., Tsai, P. J., Tang, H. J. & Ko, W. C., 2014 7月, 於: Clinical Microbiology and Infection. 20, 7, p. O428-O434

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56 引文斯高帕斯（Scopus）

N-Butylidenephthalide protects against dopaminergic neuron degeneration and α-synuclein accumulation in Caenorhabditis elegans models of Parkinson's disease

Fu, R. H., Harn, H. J., Liu, S. P., Chen, C. S., Chang, W. L., Chen, Y. M., Huang, J. E., Li, R. J., Tsai, S. Y., Hung, H. S., Shyu, W. C., Lin, S. Z. & Wang, Y. C., 2014 1月 8, 於: PloS one. 9, 1, e85305.

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68 引文斯高帕斯（Scopus）

Virulence diversity among bacteremic aeromonas isolates: Ex Vivo, animal, and clinical evidences

Po-Lin, C., Chi-Jung, W., Pei-Jane, T., Hung-Jen, T., Yin-Ching, C., Nan-Yao, L., Ching-Chi, L., Chia-Wen, L., Ming-Chi, L., Chi-Chung, C. H. W. T., Chun-Chun, O., Chang-Shi, C. & Wen-Chien, K., 2014 11月 6, 於: PloS one. 9, 11, e111213.

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38 引文斯高帕斯（Scopus）

2013

Enterohaemorrhagic Escherichia coli O157: H7 Shiga-like toxin 1 is required for full pathogenicity and activation of the p38 mitogen-activated protein kinase pathway in Caenorhabditis elegans

Chou, T. C., Chiu, H. C., Kuo, C. J., Wu, C. M., Syu, W. J., Chiu, W. T. & Chen, C. S., 2013 1月, 於: Cellular Microbiology. 15, 1, p. 82-97 16 p.

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47 引文斯高帕斯（Scopus）

Histone deacetylase inhibitor AR42 regulates telomerase activity in human glioma cells via an Akt-dependent mechanism

Yang, Y. L., Huang, P. H., Chiu, H. C., Kulp, S. K., Chen, C. S., Kuo, C. J., Chen, H. D. & Chen, C. S., 2013 5月 24, 於: Biochemical and Biophysical Research Communications. 435, 1, p. 107-112 6 p.

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18 引文斯高帕斯（Scopus）

Immobilization of the nematode caenorhabditis elegans with addressable light-induced heat knockdown (ALINK)

Chuang, H. S., Chen, H. Y., Chen, C. S. & Chiu, W. T., 2013 8月 7, 於: Lab on a Chip. 13, 15, p. 2980-2989 10 p.

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13 引文斯高帕斯（Scopus）

SESN-1 is a positive regulator of lifespan in Caenorhabditis elegans

Yang, Y. L., Loh, K. S., Liou, B. Y., Chu, I. H., Kuo, C. J., Chen, H. D. & Chen, C. S., 2013 3月, 於: Experimental Gerontology. 48, 3, p. 371-379 9 p.

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60 引文斯高帕斯（Scopus）

2012

Genome sequence of a novel human pathogen, Aeromonas aquariorum

Wu, C. J., Wang, H. C., Chen, C. S., Shu, H. Y., Kao, A. W., Chen, P. L. & Ko, W. C., 2012 8月, 於: Journal of Bacteriology. 194, 15, p. 4114-4115 2 p.

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31 引文斯高帕斯（Scopus）

2010

WWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans

Chen, C. S., Bellier, A., Kao, C. Y., Yang, Y. L., Chen, H. D., Los, F. C. O. & Aroian, R. V., 2010 3月 2, 於: PloS one. 5, 3, e9494.

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44 引文斯高帕斯（Scopus）

2009

Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans

Bellier, A., Chen, C. S., Kao, C. Y., Cinar, H. N. & Aroian, R. V., 2009 12月, 於: PLoS pathogens. 5, 12, e1000689.

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80 引文斯高帕斯（Scopus）

2008

Expression of Cry5B protein from Bacillus thuringiensis in plant roots confers resistance to root-knot nematode

Li, X. Q., Tan, A., Voegtline, M., Bekele, S., Chen, C. S. & Aroian, R. V., 2008 10月, 於: Biological Control. 47, 1, p. 97-102 6 p.

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60 引文斯高帕斯（Scopus）

2007

Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation

Chen, C. S., Wang, Y. C., Yang, H. C., Huang, P. H., Kulp, S. K., Yang, C. C., Lu, Y. S., Matsuyama, S., Chen, C. Y. & Chen, C. S., 2007 6月 1, 於: Cancer Research. 67, 11, p. 5318-5327 10 p.

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159 引文斯高帕斯（Scopus）

Peroxisome proliferator-activated receptor γ-independent suppression of androgen receptor expression by troglitazone mechanism and pharmacologic exploitation

Yang, C. C., Wang, Y. C., Wei, S., Lin, L. F., Chen, C. S., Lee, C. C., Lin, C. C. & Chen, C. S., 2007 4月 1, 於: Cancer Research. 67, 7, p. 3229-3238 10 p.

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46 引文斯高帕斯（Scopus）

2006

Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancer

Kulp, S. K., Chen, C. S., Wang, D. S., Chen, C. Y. & Chen, C. S., 2006 9月 1, 於: Clinical Cancer Research. 12, 17, p. 5199-5206 8 p.

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89 引文斯高帕斯（Scopus）

Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor

Tseng, P. H., Wang, Y. C., Weng, S. C., Weng, J. R., Chen, C. S., Brueggemeier, R. W., Shapiro, C. L., Chen, C. Y., Dunn, S. E., Pollak, M. & Chen, C. S., 2006, 於: Molecular Pharmacology. 70, 5, p. 1534-1541 8 p.

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68 引文斯高帕斯（Scopus）

Peroxisome proliferator-activated receptor γ-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells

Yang, C. C., Ku, C. Y., Wei, S., Shiau, C. W., Chen, C. S., Pinzone, J. J., Ringel, M. D. & Chen, C. S., 2006 5月, 於: Molecular Pharmacology. 69, 5, p. 1564-1570 7 p.

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36 引文斯高帕斯（Scopus）

2005

Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

Chen, C. S., Weng, S. C., Tseng, P. H., Lin, H. P. & Chen, C. S., 2005, 於: Journal of Biological Chemistry. 280, 46, p. 38879-38887 9 p.

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225 引文斯高帕斯（Scopus）

Structure-based optimization of phenylbutyrate-derived histone deacetylase inhibitors

Lu, Q., Wang, D. S., Chen, C. S., Hu, Y. D. & Chen, C. S., 2005 8月 25, 於: Journal of Medicinal Chemistry. 48, 17, p. 5530-5535 6 p.

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90 引文斯高帕斯（Scopus）

Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARγ

Shiau, C. W., Yang, C. C., Kulp, S. K., Chen, K. F., Chen, C. S., Huang, J. W. & Chen, C. S., 2005 2月 15, 於: Cancer Research. 65, 4, p. 1561-1569 9 p.

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200 引文斯高帕斯（Scopus）

2004

Growth inhibitory effects of celecoxib in human umbilical vein endothelial cells are mediated through G₁ arrest via multiple signaling mechanisms

Lin, H. P., Kulp, S. K., Tseng, P. H., Yang, Y. T., Yang, C. C., Chen, C. S. & Chen, C. S., 2004 12月, 於: Molecular cancer therapeutics. 3, 12, p. 1671-1680 10 p.

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58 引文斯高帕斯（Scopus）

Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder

Roychowdhury, S., Baiocchi, R. A., Vourganti, S., Bhatt, D., Blaser, B. W., Freud, A. G., Chou, J., Chen, C. S., Xiao, J. J., Parthun, M., Chan, K. K., Eisenbeis, C. F., Ferketich, A. K., Grever, M. R., Chen, C. S. & Caligiuri, M. A., 2004 10月 6, 於: Journal of the National Cancer Institute. 96, 19, p. 1447-1457 11 p.

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29 引文斯高帕斯（Scopus）

Zn²⁺-Chelating Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase Inhibitors

Lu, Q., Yang, Y. T., Chen, C. S., Davis, M., Byrd, J. C., Etherton, M. R., Umar, A. & Chen, C. S., 2004 1月 15, 於: Journal of Medicinal Chemistry. 47, 2, p. 467-474 8 p.

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103 引文斯高帕斯（Scopus）

2003

Bcl-xL mediates a survival mechanism independent of the phosphoinositide 3-kinase/Akt pathway in prostate cancer cells

Yang, C. C., Lin, H. P., Chen, C. S., Yang, Y. T., Tseng, P. H., Rangnekar, V. M. & Chen, C. S., 2003 7月 11, 於: Journal of Biological Chemistry. 278, 28, p. 25872-25878 7 p.

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53 引文斯高帕斯（Scopus）

陳 昌熙

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陳昌熙