郭 承翔

Postdoctoral Fellow

  • 650 引文
  • 14 h-指數
20052019
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研究成果 2005 2019

  • 650 引文
  • 14 h-指數
  • 24 Article
  • 1 Review article
2019
開啟存取
Thrombomodulin
Germ Layers
Blastomeres
Organogenesis
Zebrafish

Tumor Endothelial Marker 1 (TEM1/Endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors

Hong, Y. K., Lee, Y. C., Cheng, T. L., Lai, C. H., Hsu, C. K., Kuo, C. H., Hsu, Y. Y., Li, J. T., Chang, B. I., Ma, C. Y., Lin, S. W., Wang, K. C., Shi, G. Y. & Wu, H. L., 2019 十月, 於 : Journal of Investigative Dermatology. 139, 10, p. 2204-2214.e7

研究成果: Article

Platelet-Derived Growth Factor Receptors
Tumor Biomarkers
Wound Healing
Tumors
Fibroblasts
2018
1 引文 (Scopus)

Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing

Cheng, T. L., Chen, P. K., Huang, W. K., Kuo, C. H., Cho, C. F., Wang, K. C., Shi, G. Y., Wu, H. L. & Lai, C. H., 2018 十二月 1, 於 : Journal of Molecular Medicine. 96, 12, p. 1333-1344 12 p.

研究成果: Article

Thrombomodulin
Plasminogen
Wound Healing
Vascular Endothelial Growth Factor A
Skin
2017
23 引文 (Scopus)

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

Wu, D., Huang, R. T., Hamanaka, R. B., Krause, M., Oh, M. J., Kuo, C-H., Nigdelioglu, R., Meliton, A. Y., Witt, L., Dai, G., Civelek, M., Prabhakar, N. R., Fang, Y. & Mutlu, G. M., 2017 五月 30, 於 : eLife. 6, e25217.

研究成果: Article

開啟存取
Hypoxia-Inducible Factor 1
Endothelial cells
Vascular Endothelium
Swine
Endothelial Cells
35 引文 (Scopus)

NOTCH1 is a mechanosensor in adult arteries

Mack, J. J., Mosqueiro, T. S., Archer, B. J., Jones, W. M., Sunshine, H., Faas, G. C., Briot, A., Aragón, R. L., Su, T., Romay, M. C., McDonald, A. I., Kuo, C. H., Lizama, C. O., Lane, T. F., Zovein, A. C., Fang, Y., Tarling, E. J., De Aguiar Vallim, T. Q., Navab, M., Fogelman, A. M. 及其他2, Bouchard, L. S. & Iruela-Arispe, M. L., 2017 十二月 1, 於 : Nature communications. 8, 1, 1620.

研究成果: Article

開啟存取
arteries
shear stress
Shear stress
Calcium Signaling
Arteries
7 引文 (Scopus)

Protein Mimetic and Anticancer Properties of Monocyte-Targeting Peptide Amphiphile Micelles

Poon, C., Chowdhuri, S., Kuo, C-H., Fang, Y., Alenghat, F. J., Hyatt, D., Kani, K., Gross, M. E. & Chung, E. J., 2017 十二月 11, 於 : ACS Biomaterials Science and Engineering. 3, 12, p. 3273-3282 10 p.

研究成果: Article

Amphiphiles
Chemokine CCL2
Micelles
Pulse amplitude modulation
Peptides
3 引文 (Scopus)

Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm

Lai, C. H., Wang, K. C., Kuo, C. H., Lee, F. T., Cheng, T. L., Chang, B. I., Yang, Y. J., Shi, G. Y. & Wu, H. L., 2017 七月 1, 於 : Atherosclerosis. 262, p. 62-70 9 p.

研究成果: Article

Thrombomodulin
Dependovirus
Abdominal Aortic Aneurysm
Lectins
Angiotensin II
2015
6 引文 (Scopus)

Development of Recombinant Adeno-Associated Virus Serotype 2/8 Carrying Kringle Domains of Human Plasminogen for Sustained Expression and Cancer Therapy

Kuo, C. H., Chang, B. I., Lee, F. T., Chen, P. K., Lee, J. S., Shi, G. Y. & Wu, H. L., 2015 九月 1, 於 : Human Gene Therapy. 26, 9, p. 603-613 11 p.

研究成果: Article

Kringles
Dependovirus
Angiostatins
Plasminogen
Heterografts
11 引文 (Scopus)

FGFR1 mediates recombinant thrombomodulin domain-induced angiogenesis

Kuo, C. H., Sung, M. C., Chen, P. K., Chang, B. I., Lee, F. T., Cho, C. F., Hsieh, T. T., Huang, Y. C., Li, Y. H., Shi, G. Y., Luo, C. Y. & Wu, H. L., 2015 一月 1, 於 : Cardiovascular Research. 105, 1, p. 107-117 11 p.

研究成果: Article

Thrombomodulin
Protein C
Human Umbilical Vein Endothelial Cells
Syndecan-4
Receptor, Fibroblast Growth Factor, Type 1
35 引文 (Scopus)

Mechanosensitive PPAP2B regulates endothelial responses to atherorelevant hemodynamic forces

Wu, C., Huang, R. T., Kuo, C. H., Kumar, S., Kim, C. W., Lin, Y. C., Chen, Y. J., Birukova, A., Birukov, K. G., Dulin, N. O., Civelek, M., Lusis, A. J., Loyer, X., Tedgui, A., Dai, G., Jo, H. & Fang, Y., 2015 七月 1, 於 : Circulation Research. 117, 4, p. e41-e53

研究成果: Article

開啟存取
Phosphatidate Phosphatase
Hemodynamics
Lysophosphatidic Acid Receptors
Coronary Artery Disease
Endothelium
7 引文 (Scopus)

Thrombomodulin promotes corneal epithelial wound healing

Huang, Y. H., Ching-Chang, I., Kuo, C. H., Hsu, Y. Y., Lee, F. T., Shi, G. Y., Tseng, S. H. & Wu, H. L., 2015 三月 27, 於 : PloS one. 10, 3, e0122491.

研究成果: Article

Thrombomodulin
tissue repair
Wound Healing
cornea
growth factors
2014
49 引文 (Scopus)

Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles

Kuo, C. H., Leon, L., Chung, E. J., Huang, R. T., Sontag, T. J., Reardon, C. A., Getz, G. S., Tirrell, M. & Fang, Y., 2014 十二月 14, 於 : Journal of Materials Chemistry B. 2, 46, p. 8142-8153 12 p.

研究成果: Article

Micelles
Polyelectrolytes
MicroRNAs
Peptides
Arginine
14 引文 (Scopus)
Thrombomodulin
Endothelial Cells
Apoptosis
Starvation
Vascular Endothelium
43 引文 (Scopus)

Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis

Yang, S. M., Ka, S. M., Wu, H. L., Yeh, Y. C., Kuo, C. H., Hua, K. F., Shi, G. Y., Hung, Y. J., Hsiao, F. C., Yang, S. S., Shieh, Y. S., Lin, S. H., Wei, C. W., Lee, J. S., Yang, C. Y. & Chen, A., 2014 二月 1, 於 : Diabetologia. 57, 2, p. 424-434 11 p.

研究成果: Article

Inflammasomes
Thrombomodulin
Complement Factor B
Diabetic Nephropathies
Dependovirus
2013
14 引文 (Scopus)

Recombinant human thrombomodulin suppresses experimental abdominal aortic aneurysms induced by calcium chloride in mice

Lai, C. H., Shi, G. Y., Lee, F. T., Kuo, C. H., Cheng, T. L., Chang, B. I., Ma, C. Y., Hsu, F. C., Yang, Y. J. & Wu, H. L., 2013 十二月 1, 於 : Annals of Surgery. 258, 6, p. 1103-1110 8 p.

研究成果: Article

Calcium Chloride
Abdominal Aortic Aneurysm
Macrophages
Thrombomodulin
Inflammation
10 引文 (Scopus)

Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis

Chen, P. K., Chang, B. I., Kuo, C. H., Chen, P. S., Cho, C. F., Chang, C. F., Shi, G. Y. & Wu, H. L., 2013 十一月 1, 於 : FASEB Journal. 27, 11, p. 4520-4531 12 p.

研究成果: Article

Thrombomodulin
Plasminogen
Proteolysis
Urokinase Plasminogen Activator Receptors
Urokinase-Type Plasminogen Activator
17 引文 (Scopus)

Thrombomodulin regulates keratinocyte differentiation and promotes wound healing

Cheng, T. L., Wu, Y. T., Lai, C. H., Kao, Y. C., Kuo, C. H., Liu, S. L., Hsu, Y. Y., Chen, P. K., Cho, C. F., Wang, K. C., Lin, W. L., Chang, B. I., Chen, C. M., Weiler, H., Shi, G. Y. & Wu, H. L., 2013 一月 1, 於 : Journal of Investigative Dermatology. 133, 6, p. 1638-1645 8 p.

研究成果: Article

Thrombomodulin
Keratinocytes
Wound Healing
Skin
Calcium
2012
30 引文 (Scopus)

The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen

Kuo, C. H., Chen, P. K., Chang, B. I., Sung, M. C., Shi, C. S., Lee, J. S., Chang, C. F., Shi, G. Y. & Wu, H. L., 2012 二月 2, 於 : Blood. 119, 5, p. 1302-1313 12 p.

研究成果: Article

Thrombomodulin
Lectins
Endothelial cells
Chemotaxis
Epidermal Growth Factor Receptor
58 引文 (Scopus)

The role of thrombomodulin lectin-like domain in inflammation

Li, Y. H., Kuo, C. H., Shi, G. Y. & Wu, H. L., 2012 三月 28, 於 : Journal of biomedical science. 19, 1, 34.

研究成果: Review article

Thrombomodulin
Lectins
Inflammation
Thrombin
Anticoagulants
27 引文 (Scopus)

Thrombomodulin is an ezrin-interacting protein that controls epithelial morphology and promotes collective cell migration

Hsu, Y. Y., Shi, G. Y., Kuo, C. H., Liu, S. L., Wu, C. M., Ma, C. Y., Lin, F. Y., Yang, H. Y. & Wu, H. L., 2012 八月 1, 於 : FASEB Journal. 26, 8, p. 3440-3452 13 p.

研究成果: Article

Thrombomodulin
Cell Movement
Proteins
Actin Cytoskeleton
Actins
2011
28 引文 (Scopus)

Thrombomodulin domains attenuate atherosclerosis by inhibiting thrombin-induced endothelial cell activation

Wei, H. J., Li, Y. H., Shi, G. Y., Liu, S. L., Chang, P. C., Kuo, C. H. & Wu, H. L., 2011 十一月 1, 於 : Cardiovascular Research. 92, 2, p. 317-327 11 p.

研究成果: Article

Thrombomodulin
Thrombin
Atherosclerosis
Endothelial Cells
PAR-1 Receptor
2008
116 引文 (Scopus)

Lectin-like domain of thrombomodulin binds to its specific ligand Lewis y antigen and neutralizes lipopolysaccharide-induced inflammatory response

Shi, C. S., Shi, G. Y., Hsiao, S. M., Kao, Y. C., Kuo, K. L., Chih-Yuan, M., Kuo, C. H., Chang, B. I., Chang, C. F., Lin, C. H., Wong, C. H. & Wu, H. L., 2008 十一月 1, 於 : Blood. 112, 9, p. 3661-3670 10 p.

研究成果: Article

Thrombomodulin
Lectins
Lipopolysaccharides
Ligands
Antigens
26 引文 (Scopus)

Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells

Wu, H. L., Lin, C. I., Huang, Y. L., Chen, P. S., Kuo, C. H., Chen, M. S., Wu, G. C. C., Shi, G. Y., Yang, H. Y. & Lee, H., 2008 二月 29, 於 : Biochemical and Biophysical Research Communications. 367, 1, p. 162-168 7 p.

研究成果: Article

Thrombomodulin
Endothelial cells
Lectins
Endothelial Cells
Endothelial Growth Factors
2007
33 引文 (Scopus)

Salvianolic acid B modulates hemostasis properties of human umbilical vein endothelial cells

Shi, C. S., Huang, H. C., Wu, H. L., Kuo, C. H., Chang, B. I., Shiao, M. S. & Shi, G. Y., 2007 三月 23, 於 : Thrombosis Research. 119, 6, p. 769-775 7 p.

研究成果: Article

Human Umbilical Vein Endothelial Cells
Hemostasis
Thrombomodulin
Plasminogen Activator Inhibitor 1
Anticoagulants
2005
57 引文 (Scopus)

Evidence of human thrombomodulin domain as a novel angiogenic factor

Shi, C. S., Shi, G. Y., Chang, Y. S., Han, H. S., Kuo, C. H., Liu, C., Huang, H. C., Chang, Y. J., Chen, P. S. & Wu, H. L., 2005 四月 5, 於 : Circulation. 111, 13, p. 1627-1636 10 p.

研究成果: Article

Thrombomodulin
Angiogenesis Inducing Agents
Endothelial Cells
Human Umbilical Vein Endothelial Cells
Epidermal Growth Factor