• 3076 引文
  • 17 h-指數
20052020
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研究成果 2005 2019

篩選
Article
2019

HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection

Tseng, P. C., Kuo, C. F., Cheng, M. H., Wan, S. W., Lin, C. F., Chang, C. P., Lin, Y. S., Wu, J. J., Huang, C. C. & Chen, C. L., 2019 九月 18, 於 : Frontiers in Immunology. 10, 2147.

研究成果: Article

開啟存取
Toll-Like Receptor 2
Streptococcal Infections
Thioredoxins
Ubiquitin-Protein Ligases
Proteolysis

Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats

Kuthati, Y., Davuluri, V. N. G., Yang, C. P., Chang, H. C., Chang, C. P. & Wong, C. S., 2019 一月 1, 於 : Journal of Pain Research. 12, p. 2473-2485 13 p.

研究成果: Article

開啟存取
Melatonin MT2 Receptor
Neuralgia
Reactive Oxygen Species
Melatonin Receptors
Neuroglia
開啟存取
Breast Neoplasms
Recurrence
Mutation
Genes
Computational Biology
2018
4 引文 (Scopus)
Macrophage Migration-Inhibitory Factors
Dengue Virus
Minocycline
Autophagy
Virus Replication
2017
16 引文 (Scopus)

AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78

Chen, H. H., Chen, C. C., Lin, Y-S., Chang, P. C., Lu, Z. Y., Lin, C. F., Chen, C. L. & Chang, C-P., 2017 六月 1, 於 : Antiviral Research. 142, p. 158-168 11 p.

研究成果: Article

Dengue Virus
Virus Replication
Phosphatidylinositol 3-Kinases
Down-Regulation
Virus Diseases
10 引文 (Scopus)

Dengue virus infection increases microglial cell migration

Jhan, M. K., Tsai, T. T., Chen, C. L., Tsai, C. C., Cheng, Y. L., Lee, Y. C., Ko, C. Y., Lin, Y-S., Chang, C-P., Lin, L. T. & Lin, C. F., 2017 一月 1, 於 : Scientific reports. 7, 1, 91.

研究成果: Article

Dengue Virus
Virus Diseases
Cell Movement
Clathrin
Viral RNA
15 引文 (Scopus)

Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells

Chen, Y. D., Fang, Y. T., Cheng, Y. L., Lin, C. F., Hsu, L. J., Wang, S. Y., Anderson, R., Chang, C. P. & Lin, Y. S., 2017 十二月 1, 於 : Scientific reports. 7, 1, 5676.

研究成果: Article

Annexin A2
Annexins
Epithelial Cells
Lung
Multivesicular Bodies
10 引文 (Scopus)

Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection

Zainal, N., Chang, C. P., Cheng, Y. L., Wu, Y. W., Anderson, R., Wan, S. W., Chen, C. L., Ho, T. S., Abubakar, S. & Lin, Y. S., 2017 二月 20, 於 : Scientific reports. 7, 42998.

研究成果: Article

Interferon Type I
Dengue Virus
Virus Diseases
Interferons
Genes
3 引文 (Scopus)

S100A10 Regulates ULK1 Localization to ER–Mitochondria Contact Sites in IFN-γ-Triggered Autophagy

Chen, Y. D., Fang, Y. T., Chang, C. P., Lin, C. F., Hsu, L. J., Wu, S. R., Chiu, Y. C., Anderson, R. & Lin, Y. S., 2017 一月 6, 於 : Journal of Molecular Biology. 429, 1, p. 142-157 16 p.

研究成果: Article

Autophagy
Annexin A2
High Mobility Group Proteins
Annexins
Autophagosomes
10 引文 (Scopus)

Therapeutic effects of monoclonal antibody against dengue virus NS1 in a STAT1 knockout mouse model of dengue infection

Wan, S. W., Chen, P. W., Chen, C. Y., Lai, Y. C., Chu, Y. T., Hung, C. Y., Lee, H., Wu, H. F., Chuang, Y. C., Lin, J., Chang, C-P., Wang, S-Y., Liu, C-C., Ho, T-S., Lin, C. F., Lee, C. K., Wu-Hsieh, B. A., Anderson, R., Yeh, T-M. & Lin, Y-S., 2017 十月 15, 於 : Journal of Immunology. 199, 8, p. 2834-2844 11 p.

研究成果: Article

Dengue Virus
Dengue
Therapeutic Uses
Knockout Mice
Monoclonal Antibodies
2016
10 引文 (Scopus)

Anti-dengue virus nonstructural protein 1 antibodies contribute to platelet phagocytosis by macrophages

Wan, S. W., Yang, Y. W., Chu, Y. T., Lin, C. F., Chang, C. P., Yeh, T. M., Anderson, R. & Lin, Y. S., 2016 一月 1, 於 : Thrombosis and Haemostasis. 115, 3, p. 646-656 11 p.

研究成果: Article

Dengue Virus
Phagocytosis
Blood Platelets
Macrophages
Antibodies
27 引文 (Scopus)

Galectin-1-induced autophagy facilitates cisplatin resistance of hepatocellular carcinoma

Su, Y. C., Davuluri, G. V. N., Chen, C. H., Shiau, D. C., Chen, C. C., Chen, C. L., Lin, Y. S. & Chang, C. P., 2016 二月 1, 於 : PloS one. 11, 2, e0148408.

研究成果: Article

Galectin 1
cisplatin
autophagy
Autophagy
hepatoma
16 引文 (Scopus)
Lab-On-A-Chip Devices
Orthomyxoviridae
Viruses
Microfluidics
Human Influenza
26 引文 (Scopus)

Integrated microfluidic system for rapid detection of influenza H1N1 virus using a sandwich-based aptamer assay

Tseng, Y. T., Wang, C. H., Chang, C-P. & Lee, G. B., 2016 八月 15, 於 : Biosensors and Bioelectronics. 82, p. 105-111 7 p.

研究成果: Article

H1N1 Subtype Influenza A Virus
Microfluidics
Orthomyxoviridae
Viruses
Assays
29 引文 (Scopus)

Microglia retard dengue virus-induced acute viral encephalitis

Tsai, T. T., Chen, C. L., Lin, Y. S., Chang, C. P., Tsai, C. C., Cheng, Y. L., Huang, C. C., Ho, C. J., Lee, Y. C., Lin, L. T., Jhan, M. K. & Lin, C. F., 2016 六月 9, 於 : Scientific reports. 6, 27670.

研究成果: Article

Viral Encephalitis
Dengue Virus
Microglia
Virus Diseases
Cytotoxic T-Lymphocytes
2015
14 引文 (Scopus)

Enterovirus 71 virion-associated galectin-1 facilitates viral replication and stability

Lee, P. H., Liu, C. M., Ho, T. S., Tsai, Y. C., Lin, C. C., Wang, Y. F., Chen, Y. L., Yu, C. K., Wang, S. M., Liu, C. C., Shiau, A. L., Lei, H. Y. & Chang, C. P., 2015 二月 23, 於 : PloS one. 10, 2, e0116278.

研究成果: Article

Galectin 1
Enterovirus
virus replication
virion
Virion
5 引文 (Scopus)
Macrophage Migration-Inhibitory Factors
Autophagy
Concanavalin A
Hepatocellular Carcinoma
Cell Death
2014
11 引文 (Scopus)

An integrated microfluidic platform for rapid detection and subtyping of influenza viruses from clinical samples

Tai, C. H., Tsai, Y. C., Wang, C. H., Ho, T. S., Chang, C. P. & Lee, G. B., 2014 三月, 於 : Microfluidics and Nanofluidics. 16, 3, p. 501-512 12 p.

研究成果: Article

influenza
viruses
Viruses
Microfluidics
platforms
24 引文 (Scopus)
Antibody-Dependent Enhancement
Dengue Virus
Interleukin-10
Monocytes
1-Phosphatidylinositol 4-Kinase
30 引文 (Scopus)
Microfluidics
Immunoassay
Nanoparticles
Human Influenza
Infection
2013
10 引文 (Scopus)

Clitocybe nuda activates dendritic cells and acts as A DNA vaccine adjuvant

Chen, M. H., Li, W. S., Lue, Y. S., Chu, C. L., Pan, I. H., Ko, C. H., Chen, D. Y., Lin, C. H., Lin, S. H., Chang, C. P. & Lin, C. C., 2013 九月 23, 於 : Evidence-based Complementary and Alternative Medicine. 2013, 761454.

研究成果: Article

DNA Vaccines
Dendritic Cells
Water
Cancer Vaccines
JNK Mitogen-Activated Protein Kinases
42 引文 (Scopus)

Targeting NFKB by autophagy to polarize hepatoma-associated macrophage differentiation

Chang, C-P., Su, Y. C., Lee, P. H. & Lei, H. Y., 2013 一月 1, 於 : Autophagy. 9, 4, p. 619-621 3 p.

研究成果: Article

Autophagy
Hepatocellular Carcinoma
Macrophages
Neoplasms
Toll-Like Receptor 2
64 引文 (Scopus)
Autophagy
Hepatocellular Carcinoma
Macrophages
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
2012
41 引文 (Scopus)

Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation

Chuang, Y. C., Su, W. H., Lei, H. Y., Lin, Y. S., Liu, H. S., Chang, C. P. & Yeh, T. M., 2012 五月 22, 於 : PloS one. 7, 5, e37613.

研究成果: Article

Macrophage Migration-Inhibitory Factors
autophagy
Autophagy
reactive oxygen species
Reactive Oxygen Species
2 引文 (Scopus)

Steric recognition of T-cell receptor contact residues is required to map mutant epitopes by immunoinformatical programmes

Hsu, S. C., Chang, C. P., Tsai, C. Y., Hsieh, S. H., Wu-Hsieh, B. A., Lo, Y. S. & Yang, J. M., 2012 六月 1, 於 : Immunology. 136, 2, p. 139-152 14 p.

研究成果: Article

T-Cell Antigen Receptor
Epitopes
T-Lymphocyte Epitopes
Amino Acid Substitution
Peptide T
2011
26 引文 (Scopus)
autophagy
GTP Phosphohydrolases
Autophagy
guanosinetriphosphatase
concanavalin A
2010
20 引文 (Scopus)

Endothelial cells are damaged by autophagic induction before hepatocytes in Con A-induced acute hepatitis

Yang, M. C., Chang, C. P. & Lei, H. Y., 2010 六月 13, 於 : International Immunology. 22, 8, p. 661-670 10 p.

研究成果: Article

Autophagy
Hepatitis
Hepatocytes
Endothelial Cells
T-Lymphocytes
16 引文 (Scopus)
Thioacetamide
Liver Cirrhosis
Hepatocellular Carcinoma
Immunity
Fibrosis
2009
54 引文 (Scopus)

A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA

Yen, M. C., Lin, C. C., Chen, Y. L., Huang, S. S., Yang, H. J., Chang, C. P., Lei, H. Y. & Lai, M. D., 2009 一月 15, 於 : Clinical Cancer Research. 15, 2, p. 641-649 9 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Skin Neoplasms
Small Interfering RNA
Neoplasms
Therapeutics
72 引文 (Scopus)
Concanavalin A
Lectins
Hepatocellular Carcinoma
Liver
Tumors
2008
25 引文 (Scopus)
Inbred NOD Mouse
SCID Mice
Autophagy
Concanavalin A
Hepatitis
2007
127 引文 (Scopus)

Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model

Chang, C. P., Yang, M. C., Liu, H. S., Lin, Y. S. & Lei, H. Y., 2007 二月 1, 於 : Hepatology. 45, 2, p. 286-296 11 p.

研究成果: Article

Autophagy
Therapeutic Uses
Concanavalin A
Hepatocellular Carcinoma
Mitochondria
53 引文 (Scopus)

Induction of autophagy by concanavalin A and its application in anti-tumor therapy

Lei, H. Y. & Chang, C-P., 2007 一月 1, 於 : Autophagy. 3, 4, p. 402-404 3 p.

研究成果: Article

Autophagy
Concanavalin A
Neoplasms
Mannose
Lectins
2005
2 引文 (Scopus)

A cellular ELISA to screen lectin-like compounds for cancer cell binding

Chang, C-P., Cheng, W. C. & Lei, H. Y., 2005 五月 1, 於 : Letters in Drug Design and Discovery. 2, 3, p. 182-188 7 p.

研究成果: Article

Lectins
Enzyme-Linked Immunosorbent Assay
Neoplasms
Membrane Glycoproteins
Biological Products
39 引文 (Scopus)

IL-24 inhibits the growth of hepatoma cells in vivo

Chen, W. Y., Cheng, Y. T., Lei, H. Y., Chang, C. P., Wang, C. W. & Chang, M. S., 2005 九月 1, 於 : Genes and Immunity. 6, 6, p. 493-499 7 p.

研究成果: Article

Hepatocellular Carcinoma
Growth
Electroporation
Neoplasms
Genes