王 智揚

Postdoctoral Fellow

  • 732 引文
  • 11 h-指數
20132019
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研究成果 2013 2019

  • 732 引文
  • 11 h-指數
  • 34 Article
  • 1 Review article
2019

Immune effector monocyte–neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer

Hagerling, C., Gonzalez, H., Salari, K., Wang, C. Y., Lin, C., Robles, I., van Gogh, M., Dejmek, A., Jirström, K. & Werb, Z., 2019 十月 22, 於 : Proceedings of the National Academy of Sciences of the United States of America. 116, 43, p. 21704-21714 11 p.

研究成果: Article

開啟存取
Monocytes
Neutrophils
Breast Neoplasms
Neoplasms
Lung

MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy

Owyong, M., Chou, J., van den Bijgaart, R. J. E., Kong, N., Efe, G., Maynard, C., Talmi-Frank, D., Solomonov, I., Koopman, C., Hadler-Olsen, E., Headley, M., Lin, C., Wang, C. Y., Sagi, I., Werb, Z. & Plaks, V., 2019 一月 1, 於 : Life Science Alliance. 2, 6, e201800226.

研究成果: Article

開啟存取
gelatinase B
Matrix Metalloproteinase 9
breast neoplasms
cancer
Breast Neoplasms
開啟存取
Breast Neoplasms
Recurrence
Mutation
Genes
Computational Biology
1 引文 (Scopus)

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

Gbenedio, O. M., Bonnans, C., Grun, D., Wang, C. Y., Hatch, A. J., Mahoney, M. R., Barras, D., Matli, M., Miao, Y., Christopher Garcia, K., Tejpar, S., Delorenzi, M., Venook, A. P., Nixon, A. B., Warren, R. S., Roose, J. P. & Depeille, P., 2019 八月 8, 於 : JCI Insight. 4, 15, e127552.

研究成果: Article

開啟存取
Colorectal Neoplasms
Biomarkers
Therapeutics
Organoids
Drug Therapy
2018
11 引文 (Scopus)

Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient

Phan, N. N., Wang, C. Y., Li, K. L., Chen, C. F., Chiao, C. C., Yu, H. G., Huang, P. L. & Lin, Y. C., 2018 一月 1, 於 : Oncotarget. 9, 6, p. 6977-6992 16 p.

研究成果: Article

開啟存取
Breast Neoplasms
Recurrence
Survival
cdc Genes
Genes
5 引文 (Scopus)

Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis

Cooke, D. L., McCoy, D. B., Halbach, V. V., Hetts, S. W., Amans, M. R., Dowd, C. F., Higashida, R. T., Lawson, D., Nelson, J., Wang, C-Y., Kim, H., Werb, Z., McCulloch, C., Hashimoto, T., Su, H. & Sun, Z., 2018 二月 1, 於 : Translational Stroke Research. 9, 1, p. 20-33 14 p.

研究成果: Article

Intracranial Aneurysm
Endothelial Cells
Biopsy
Gene Expression
Aneurysm
1 引文 (Scopus)
Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines
6 引文 (Scopus)

Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells

Sun, Z., Wang, C. Y., Lawson, D. A., Kwek, S., Velozo, H. G., Owyong, M., Lai, M. D., Fong, L., Wilson, M., Su, H., Werb, Z. & Cooke, D. L., 2018 一月 1, 於 : Oncotarget. 9, 13, p. 10945-10961 17 p.

研究成果: Article

RNA Sequence Analysis
Transcriptome
Endothelial Cells
Breast Neoplasms
Genes
2017
7 引文 (Scopus)

Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells

Hung, Y. H., Huang, H. L., Chen, W. C., Yen, M. C., Cho, C. Y., Weng, T. Y., Wang, C. Y., Chen, Y. L., Chen, L. T. & Lai, M. D., 2017 二月, 於 : Oncology Reports. 37, 2, p. 969-978 10 p.

研究成果: Article

Cyclin A2
Argininosuccinate Lyase
Cytoplasm
Liver
Growth
14 引文 (Scopus)

Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer

Shan, Y. S., Hsu, H. P., Lai, M. D., Hung, Y. H., Wang, C. Y., Yen, M. C. & Chen, Y. L., 2017 一月 1, 於 : Oncology Letters. 14, 4, p. 4517-4526 10 p.

研究成果: Article

Cyclin D1
Stomach Neoplasms
Cyclin D2
Stomach
Cyclin D
12 引文 (Scopus)

GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis

Shahi, P., Wang, C. Y., Chou, J., Hagerling, C., Gonzalez Velozo, H., Ruderisch, A., Yu, Y., Lai, M. D. & Werb, Z., 2017 十月 5, 於 : Oncogene. 36, 40, p. 5567-5575 9 p.

研究成果: Article

Semaphorins
Breast
Epithelial Cells
Breast Neoplasms
Neoplasm Metastasis
1 引文 (Scopus)

Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction

Thuy, T. D., Phan, N. N., Wang, C. Y., Yu, H. G., Wang, S. Y., Huang, P. L., Do, Y. Y. & Lin, Y. C., 2017 一月 1, 於 : Molecular Medicine Reports. 15, 5, p. 2949-2956 8 p.

研究成果: Article

開啟存取
Therapeutic Uses
Medical problems
Experimental Diabetes Mellitus
Cardiomegaly
Bioinformatics
3 引文 (Scopus)

PSMB5 plays a dual role in cancer development and immunosuppression

Wang, C. Y., Li, C. Y., Hsu, H. P., Cho, C. Y., Yen, M. C., Weng, T. Y., Chen, W. C., Hung, Y. H., Lee, K. T., Hung, J. H., Chen, Y. L. & Lai, M. D., 2017 一月 1, 於 : American Journal of Cancer Research. 7, 11, p. 2103-2120 18 p.

研究成果: Article

Immunosuppression
Neoplasms
Proteasome Endopeptidase Complex
Computational Biology
Macrophages
6 引文 (Scopus)

Silencing of argininosuccinate lyase inhibits colorectal cancer formation

Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 2017 一月, 於 : Oncology Reports. 37, 1, p. 163-170 8 p.

研究成果: Article

Argininosuccinate Lyase
Colorectal Neoplasms
Colonic Neoplasms
Nitric Oxide
Small Interfering RNA
22 引文 (Scopus)

Voltage-gated calcium channels: Novel targets for cancer therapy

Phan, N. N., Wang, C. Y., Chen, C. F., Sun, Z., Lai, M. D. & Lin, Y. C., 2017 一月 1, 於 : Oncology Letters. 14, 2, p. 2059-2074 16 p.

研究成果: Article

Calcium Channels
Genes
Neoplasms
Brain Neoplasms
Kidney Neoplasms
5 引文 (Scopus)

ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression

Shahi, P., Wang, C. Y., Lawson, D. A., Slorach, E. M., Lu, A., Yu, Y., Lai, M. D., Velozo, H. G. & Werb, Z., 2017 三月 21, 於 : Proceedings of the National Academy of Sciences of the United States of America. 114, 12, p. 3169-3174 6 p.

研究成果: Article

Down-Regulation
Breast Neoplasms
GATA3 Transcription Factor
Breast
Epithelial Cells
2016
10 引文 (Scopus)

Cancer stem cell marker CD90 inhibits ovarian cancer formation via β3 integrin

Chen, W. C., Hsu, H. P., Li, C. Y., Yang, Y. J., Hung, Y. H., Cho, C. Y., Wang, C. Y., Weng, T. Y. & Lai, M. D., 2016 十一月, 於 : International Journal of Oncology. 49, 5, p. 1881-1889 9 p.

研究成果: Article

Neoplastic Stem Cells
Integrins
Ovarian Neoplasms
Growth
Anoikis
16 引文 (Scopus)

Differential expression pattern of THBS1 and THBS2 in lung cancer: Clinical outcome and a systematic-analysis of microarray databases

Weng, T. Y., Wang, C. Y., Hung, Y. H., Chen, W. C., Chen, Y. L. & Lai, M. D., 2016 八月, 於 : PloS one. 11, 8, e0161007.

研究成果: Article

Thrombospondin 1
lung neoplasms
Microarray Analysis
Microarrays
adenocarcinoma
10 引文 (Scopus)

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

Cho, C. Y., Lee, K. T., Chen, W. C., Wang, C. Y., Chang, Y. S., Huang, H. L., Hsu, H. P., Yen, M. C., Lai, M. Z. & Lai, M. D., 2016 三月 22, 於 : Oncotarget. 7, 12, p. 14586-14604 19 p.

研究成果: Article

Phosphotransferases
Breast Neoplasms
Proline
Growth
Down-Regulation
3 引文 (Scopus)
Indican
Stem cells
Mesenchymal Stromal Cells
Chronic Renal Insufficiency
Regeneration
25 引文 (Scopus)

Systematic analysis of gene expression alterations and clinical outcomes for long-chain acyl-coenzyme A synthetase family in cancer

Chen, W. C., Wang, C. Y., Hung, Y. H., Weng, T. Y., Yen, M. C. & Lai, M. D., 2016 五月 1, 於 : PloS one. 11, 5, e0155660.

研究成果: Article

Coenzyme A Ligases
acyl coenzyme A
ligases
Gene expression
prognosis
2015
10 引文 (Scopus)

Argininosuccinate lyase is a potential therapeutic target in breast cancer

Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 2015 十二月 1, 於 : Oncology Reports. 34, 6, p. 3131-3139 9 p.

研究成果: Article

Argininosuccinate Lyase
Breast Neoplasms
Cyclin A2
Small Interfering RNA
Autophagy
4 引文 (Scopus)

Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels

Sun, Z., Lawson, D. A., Sinclair, E., Wang, C. Y., Lai, M. D., Hetts, S. W., Higashida, R. T., Dowd, C. F., Halbach, V. V., Werb, Z., Su, H. & Cooke, D. L., 2015 九月 1, 於 : Biotechnology Reports. 7, p. 157-165 9 p., 106.

研究成果: Article

Transcriptome
Endothelial Cells
Biopsy
Flow Cytometry
Leukocytes
100 引文 (Scopus)

Matrix metalloproteinases in stem cell regulation and cancer

Kessenbrock, K., Wang, C. Y. & Werb, Z., 2015 五月 1, 於 : Matrix Biology. 44-46, p. 184-190 7 p.

研究成果: Review article

開啟存取
Neoplastic Stem Cells
Matrix Metalloproteinases
Neoplasms
Developmental Biology
Matrix Metalloproteinase Inhibitors
30 引文 (Scopus)

Meta-analysis of public microarray datasets reveals voltage-gated calcium gene signatures in clinical cancer patients

Wang, C. Y., Lai, M. D., Phan, N. N., Sun, Z. & Lin, Y. C., 2015 七月 6, 於 : PloS one. 10, 7, e0125766.

研究成果: Article

Calcium Channels
Microarrays
meta-analysis
calcium channels
Meta-Analysis
21 引文 (Scopus)

RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth

Depeille, P., Henricks, L. M., Van De Ven, R. A. H., Lemmens, E., Wang, C. Y., Matli, M., Werb, Z., Haigis, K. M., Donner, D., Warren, R. & Roose, J. P., 2015 六月 1, 於 : Nature Cell Biology. 17, 6, p. 804-815 12 p.

研究成果: Article

Epithelial Cells
Growth
Colorectal Neoplasms
Mutation
Epithelium
326 引文 (Scopus)

Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

Lawson, D. A., Bhakta, N. R., Kessenbrock, K., Prummel, K. D., Yu, Y., Takai, K., Zhou, A., Eyob, H., Balakrishnan, S., Wang, C. Y., Yaswen, P., Goga, A. & Werb, Z., 2015 十月 1, 於 : Nature. 526, 7571, p. 131-135 5 p.

研究成果: Article

Single-Cell Analysis
Stem Cells
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
17 引文 (Scopus)

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer

Chen, W. C., Chang, Y. S., Hsu, H. P., Yen, M. C., Huang, H. L., Cho, C. Y., Wang, C. Y., Weng, T. Y., Lai, P. T., Chen, C. S., Lin, Y. J. & Lai, M. D., 2015 一月 1, 於 : Oncotarget. 6, 40, p. 42923-42937 15 p.

研究成果: Article

AMP-Activated Protein Kinases
Liver Neoplasms
Integrins
Neoplastic Stem Cells
Neoplasms
15 引文 (Scopus)

The transcriptional repressor ZNF503/Zeppo2 promotes mammary epithelial cell proliferation and enhances cell invasion

Shahi, P., Slorach, E. M., Wang, C-Y., Chou, J., Lu, A., Ruderisch, A. & Werb, Z., 2015 二月 6, 於 : Journal of Biological Chemistry. 290, 6, p. 3803-3813 11 p.

研究成果: Article

開啟存取
Cell proliferation
Breast
Epithelial Cells
Zinc Fingers
Cell Proliferation
2014
10 引文 (Scopus)

A novel cancer therapeutic using thrombospondin 1 in dendritic cells

Weng, T. Y., Huang, S. S., Yen, M. C., Lin, C. C., Chen, Y. L., Lin, C. M., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 一月 1, 於 : Molecular Therapy. 22, 2, p. 292-302 11 p.

研究成果: Article

Thrombospondin 1
Dendritic Cells
Neoplasms
Small Interfering RNA
Therapeutics
7 引文 (Scopus)

DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model

Weng, T. Y., Yen, M. C., Huang, C. T., Hung, J. J., Chen, Y. L., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 一月 1, 於 : Gene Therapy. 21, 10, p. 888-896 9 p.

研究成果: Article

DNA Vaccines
Transgenic Mice
Lung Neoplasms
Therapeutic Uses
Neoplasms
11 引文 (Scopus)

Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma

Hung, Y. U. H., Chan, Y. I. S., Chang, Y. S., Lee, K. T., Hsu, H. P., Yen, M. C., Chen, W. C., Wang, C. Y. & Lai, M. D., 2014 一月 1, 於 : Oncology Reports. 31, 6, p. 2797-2803 7 p.

研究成果: Article

Acyl Coenzyme A
Hepatocellular Carcinoma
Fatty Acids
Enzymes
Nonesterified Fatty Acids
7 引文 (Scopus)
Gene Dosage
CHO Cells
Transfer RNA
Codon
Genes
11 引文 (Scopus)
Arsenic
Hypertrophy
Rats
Cardiomegaly
Skin Neoplasms
2013
5 引文 (Scopus)

An HDAC inhibitor enhances cancer therapeutic efficiency of RNA polymerase III promoter-driven IDO shRNA

Yen, M. C., Weng, T. Y., Chen, Y. L., Lin, C. C., Chen, C. Y., Wang, C. Y., Chao, H. L., Chen, C. S. & Lai, M. D., 2013 六月 1, 於 : Cancer Gene Therapy. 20, 6, p. 351-357 7 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
RNA Polymerase III
Histone Deacetylase Inhibitors
Small Interfering RNA
Neoplasms