Chun Hei Antonio Cheung

2024

Benign polymorphisms in the BRCA genes with linkage disequilibrium is associated with cancer characteristics

Lee, K. T., Chen, D. P., Loh, Z. J., Chung, W. P., Wang, C. Y., Chen, P. S., Cheung, C. H. A., Chang, C. P. & Hsu, H. P., 2024 12月, 於: Cancer Science. 115, 12, p. 3973-3985 13 p.

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The SMAC mimetic GDC-0152 is a direct ABCB1-ATPase activity modulator and BIRC5 expression suppressor in cancer cells

Lin, I. L., Lin, Y. T., Chang, Y. C., Kondapuram, S. K., Lin, K. H., Chen, P. C., Kuo, C. Y., Coumar, M. S. & Cheung, C. H. A., 2024 4月, 於: Toxicology and Applied Pharmacology. 485, 116888.

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2 引文斯高帕斯（Scopus）

2022

Development of a cancer cells self-activating and miR-125a-5p expressing poly-pharmacological nanodrug for cancer treatment

Chang, Y. C., Shieh, M. C., Chang, Y. H., Huang, W. L., Su, W. C., Cheng, F. Y. & Cheung, C. H. A., 2022 8月, 於: International journal of molecular medicine. 50, 2, 102.

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3 引文斯高帕斯（Scopus）

Early Aβ42 Exposure Causes Learning Impairment in Later Life

Cheng, K. C., Cheung, C. H. A. & Chiang, H. C., 2022 5月 18, 於: Aging and Disease. 13, 3, p. 868-883 16 p.

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1 引文斯高帕斯（Scopus）

FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer

Chung, W. P., Huang, W. L., Liao, W. A., Hung, C. H., Chiang, C. W., Cheung, C. H. A. & Su, W. C., 2022 12月, 於: Scientific reports. 12, 1, 241.

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6 引文斯高帕斯（Scopus）

Low expression of cytosolic NOTCH1 predicts poor prognosis of breast cancer patients

Chen, Y-L., Lee, K-T., Wang, C-Y., Shen, C-H., Chen, S-C., Chung, W-P., Hsu, Y-T., Kuo, Y-L., Chen, P-S., Cheung, C. H. A., Chang, C-P., Shen, M-R. & Hsu, H-P., 2022, 於: American Journal of Cancer Research. 12, 5, p. 2084-2101 18 p.

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2021

Rac1 and Akt Exhibit Distinct Roles in Mediating Aβ-Induced Memory Damage and Learning Impairment

Cheng, K. C., Chen, Y. H., Wu, C. L., Lee, W. P., Cheung, C. H. A. & Chiang, H. C., 2021 10月, 於: Molecular Neurobiology. 58, 10, p. 5224-5238 15 p.

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5 引文斯高帕斯（Scopus）

Survivin - caspase protein-protein interaction: Experimental evidence and computational investigations to decipher the hotspot residues for drug targeting

Sarvagalla, S., Lin, T. Y., Kondapuram, S. K., Cheung, C. H. A. & Coumar, M. S., 2021 4月 5, 於: Journal of Molecular Structure. 1229, 129619.

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11 引文斯高帕斯（Scopus）

YM155 and BIRC5 downregulation induce genomic instability via autophagy-mediated ROS production and inhibition in DNA repair

Cheng, S. M., Lin, T. Y., Chang, Y. C., Lin, I. W., Leung, E. & Cheung, C. H. A., 2021 4月, 於: Pharmacological Research. 166, 105474.

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19 引文斯高帕斯（Scopus）

2020

BIRC5/Survivin is a novel ATG12–ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells

Lin, T. Y., Chan, H. H., Chen, S. H., Sarvagalla, S., Chen, P. S., Coumar, M. S., Cheng, S. M., Chang, Y. C., Lin, C. H., Leung, E. & Cheung, C. H. A., 2020 7月 2, 於: Autophagy. 16, 7, p. 1296-1313 18 p.

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95 引文斯高帕斯（Scopus）

Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells

Chang, Y. C., Cheung, C. H. A. & Kuo, Y. L., 2020 6月 30, 於: Frontiers in Cell and Developmental Biology. 8, 485.

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4 引文斯高帕斯（Scopus）

The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells

Chang, Y. C., Kondapuram, S. K., Yang, T. H., Syed, S. B., Cheng, S. M., Lin, T. Y., Lin, Y. C., Coumar, M. S., Chang, J. Y., Leung, E. & Cheung, C. H. A., 2020 8月 15, 於: Toxicology and Applied Pharmacology. 401, 115080.

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14 引文斯高帕斯（Scopus）

2019

Aging-induced Akt activation involves in aging-related pathologies and Aβ-induced toxicity

Chen, Y. R., Li, Y. H., Hsieh, T. C., Wang, C. M., Cheng, K. C., Wang, L., Lin, T. Y., Cheung, C. H. A., Wu, C. L. & Chiang, H. C., 2019 8月, 於: Aging Cell. 18, 4, e12989.

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26 引文斯高帕斯（Scopus）

Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli

Tsai, S. L., Chang, Y. C., Sarvagalla, S., Wang, S., Coumar, M. S. & Cheung, C. H. A., 2019 8月, 於: Protein Expression and Purification. 160, p. 73-83 11 p.

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8 引文斯高帕斯（Scopus）

Mutation of the PTCH1 gene predicts recurrence of breast cancer

Wang, C. Y., Chang, Y. C., Kuo, Y. L., Lee, K. T., Chen, P. S., Cheung, C. H. A., Chang, C. P., Phan, N. N., Shen, M. R. & Hsu, H. P., 2019 11月 8, 於: Scientific reports. 9, 1, 1 p., 16359.

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44 引文斯高帕斯（Scopus）

2018

Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies

Ji, X. R., Cheng, K. C., Chen, Y. R., Lin, T. Y., Cheung, C. H. A., Wu, C. L. & Chiang, H. C., 2018 3月, 於: FASEB Journal. 32, 3, p. 1375-1387 13 p.

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15 引文斯高帕斯（Scopus）

2017

HDAC2 and HDAC5 up-regulations modulate survivin and miR-125a-5p expressions and promote hormone therapy resistance in estrogen receptor positive breast cancer cells

Huang, W. T., Tsai, Y. H., Chen, S. H., Kuo, C. W., Kuo, Y. L., Lee, K. T., Chen, W. C., Wu, P. C., Chuang, C. Y., Cheng, S. M., Lin, C. H., Leung, E. Y., Chang, Y. C. & Cheung, C. H. A., 2017 12月 13, 於: Frontiers in Pharmacology. 8, DEC, 902.

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31 引文斯高帕斯（Scopus）

Topical ophthalmic formulation of trichostatin A and SurR9-C84A for quick recovery post-alkali burn of corneal haze

Roy, K., Cheung, C. H. A., Kanwar, R. K., Sandhir, R. & Kanwar, J. R., 2017 5月 5, 於: Frontiers in Pharmacology. 8, MAY, 223.

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3 引文斯高帕斯（Scopus）

2016

Delivery of a survivin Promoter-Driven antisense Survivin-Expressing plasmid DNA as a cancer therapeutic: A proof-of-concept study

Lin, K. Y., Cheng, S. M., Tsai, S. L., Tsai, J. Y., Lin, C. H. & Cheung, C. H. A., 2016 5月 3, 於: OncoTargets and Therapy. 9, p. 2601-2613 13 p.

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10 引文斯高帕斯（Scopus）

Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and: In vitro testing for the anti-cancer drug target-survivin

Sarvagalla, S., Cheung, C. H. A., Tsai, J. Y., Hsieh, H. P. & Coumar, M. S., 2016, 於: RSC Advances. 6, 38, p. 31947-31959 13 p.

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34 引文斯高帕斯（Scopus）

E-Cadherin Aptamer-Conjugated Delivery of Doxorubicin for Targeted Inhibition of Prostate Cancer Cells

Chaudhary, R., Roy, K., Kanwar, R. K., Veedu, R. N., Krishnakumar, S., Cheung, C. H. A., Verma, A. K. & Kanwar, J. R., 2016, 於: Australian Journal of Chemistry. 69, 10, p. 1108-1116 9 p.

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6 引文斯高帕斯（Scopus）

Inhibition of HDAC3- and HDAC6-promoted survivin expression plays an important role in SAHA-induced autophagy and viability reduction in breast cancer cells

Lee, J. Y. C., Kuo, C. W., Tsai, S. L., Cheng, S. M., Chen, S. H., Chan, H. H., Lin, C. H., Lin, K. Y., Li, C. F., Kanwar, J. R., Leung, E. Y., Cheung, C. C. H., Huang, W. J., Wang, Y. C. & Cheung, C. H. A., 2016 3月 31, 於: Frontiers in Pharmacology. 7, MAR, 81.

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58 引文斯高帕斯（Scopus）

2015

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

Roy, K., Kanwar, R. K., Krishnakumar, S., Cheung, C. H. A. & Kanwar, J. R., 2015 2月 2, 於: International journal of nanomedicine. 10, p. 1019-1043 25 p.

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22 引文斯高帕斯（Scopus）

Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy

Roy, K., Kanwar, R. K., Antonio Cheung, C. H., Lee Fleming, C., Veedu, R. N., Krishnakumar, S. & Kanwar, J. R., 2015, 於: RSC Advances. 5, 37, p. 29008-29016 9 p.

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19 引文斯高帕斯（Scopus）

O⁶-methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

Chen, S. H., Kuo, C. C., Li, C. F., Cheung, C. H. A., Tsou, T. C., Chiang, H. C., Yang, Y. N., Chang, S. L., Lin, L. C., Pan, H. Y., Chang, K. Y. & Chang, J. Y., 2015 9月 1, 於: International Journal of Cancer. 137, 6, p. 1291-1305 15 p.

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24 引文斯高帕斯（Scopus）

YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells

Cheng, S. M., Chang, Y. C., Liu, C. Y., Lee, J. Y. C., Chan, H. H., Kuo, C. W., Lin, K. Y., Tsai, S. L., Chen, S. H., Li, C. F., Leung, E., Kanwar, J. R., Huang, C. C., Chang, J. Y. & Cheung, C. H. A., 2015 1月, 於: British Journal of Pharmacology. 172, 1, p. 214-234 21 p.

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83 引文斯高帕斯（Scopus）

2014

The inducible nitric-oxide synthase (iNOS)/Src axis mediates toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon- β synthesis in macrophages

Hsieh, M. Y., Chang, M. Y., Chen, Y. J., Li, Y. K., Chuang, T. H., Yu, G. Y., Cheung, C. H. A., Chen, H. C., Maa, M. C. & Leu, T. H., 2014 3月 30, 於: Journal of Biological Chemistry. 289, 13, p. 9208-9220 13 p.

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18 引文斯高帕斯（Scopus）

2013

Autophagy induced by cathepsin S inhibition induces early ROS production, oxidative DNA damage, and cell death via xanthine oxidase

Huang, C. C., Chen, K. L., Cheung, C. H. A. & Chang, J. Y., 2013 12月, 於: Free Radical Biology and Medicine. 65, p. 1473-1486 14 p.

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57 引文斯高帕斯（Scopus）

2012

Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer

Ma, L., Qiao, H., He, C., Yang, Q., Cheung, C. H. A., Kanwar, J. R. & Sun, X., 2012 4月, 於: Investigational New Drugs. 30, 2, p. 508-517 10 p.

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50 引文斯高帕斯（Scopus）

Targeting cathepsin S induces tumor cell autophagy via the EGFR-ERK signaling pathway

Chen, K. L., Chang, W. S. W., Cheung, C. H. A., Lin, C. C., Huang, C. C., Yang, Y. N., Kuo, C. P., Kuo, C. C., Chang, Y. H., Liu, K. J., Wu, C. M. & Chang, J. Y., 2012 4月 1, 於: Cancer Letters. 317, 1, p. 89-98 10 p.

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66 引文斯高帕斯（Scopus）

2011

BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells

Cheung, C. H. A., Lin, W. H., HsuJohn, J. T. A., Hour, T. C., Yeh, T. K., Ko, S., Lien, T. W., Coumar, M. S., Liu, J. F., Lai, W. Y., Shiao, H. Y., Lee, T. R., Hsieh, H. P. & Chang, J. Y., 2011 8月 24, 於: PloS one. 6, 8, e23485.

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20 引文斯高帕斯（Scopus）

Enhancement of non-homologous end joining DNA repair capacity confers cancer cells resistance to the novel selenophene compound, D-501036

Yang, Y. N., Chou, K. M., Pan, W. Y., Chen, Y. W., Tsou, T. C., Yeh, S. C., Cheung, C. H. A., Chen, L. T. & Chang, J. Y., 2011 10月 1, 於: Cancer Letters. 309, 1, p. 110-118 9 p.

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7 引文斯高帕斯（Scopus）

Investigations of survivin: The past, present and future

Cheung, C. H. A., Cheng, L. T., Chang, K. Y., Chen, H. H. & Chang, J. Y., 2011 1月 1, 於: Frontiers in Bioscience. 16, 3, p. 952-961 10 p.

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54 引文斯高帕斯（Scopus）

2010

A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy

Cheung, C. H. A., Sun, X., Kanwar, J. R., Bai, J. Z., Cheng, L. T. & Krissansen, G. W., 2010 10月 1, 於: Cancer Cell International. 10, 36.

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40 引文斯高帕斯（Scopus）

Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes

Cheung, C. H. A., Wu, S. Y., Lee, T. R., Chang, C. Y., Wu, J. S., Hsieh, H. P. & Chang, J. Y., 2010, 於: PloS one. 5, 9, p. 1-11 11 p., e12564.

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41 引文斯高帕斯（Scopus）

Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells

Hsieh, C. C., Kuo, Y. H., Kuo, C. C., Chen, L. T., Cheung, C. H. A., Chao, T. Y., Lin, C. H., Pan, W. Y., Chang, C. Y., Chien, S. C., Chen, T. W., Lung, C. C. & Chang, J. Y., 2010 5月 1, 於: Biochemical Pharmacology. 79, 9, p. 1261-1271 11 p.

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29 引文斯高帕斯（Scopus）

Proliferative and protective effects of SurR9-C84A on differentiated neural cells

Baratchi, S., Kanwar, R. K., Cheung, C. H. A. & Kanwar, J. R., 2010 10月, 於: Journal of Neuroimmunology. 227, 1-2, p. 120-132 13 p.

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26 引文斯高帕斯（Scopus）

Recent advances in anti-survivin treatments for cancer

Kanwar, R. K., Cheung, C-H., Chang, J-Y. & Kanwar, J. R., 2010 6月 18, 於: Current Medicinal Chemistry. 17, 15, p. 1509-1515 7 p.

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71 引文斯高帕斯（Scopus）

Targeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells

Cheung, C. H. A., Chen, H. H., Cheng, L. T., Lyu, K. W., Kanwar, J. R. & Chang, J. Y., 2010 4月 15, 於: Molecular cancer. 9, 77.

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46 引文斯高帕斯（Scopus）

2009

Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

Cheung, C. H. A., Chen, H. H., Kuo, C. C., Chang, C. Y., Coumar, M. S., Hsieh, H. P. & Chang, J. Y., 2009 7月 3, 於: Molecular cancer. 8, 43.

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68 引文斯高帕斯（Scopus）

張 雋曦

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張雋曦