張 雋曦

Associate Professor

  • 2905 引文
  • 20 h-指數
20092019
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個人檔案

學歷

  • 2007 紐西蘭奧克大學分子醫學博士

經歷

  • 2011~2016 國立成功大學藥理研究所助理教授
  • 2016~~ 迄今 國立成功大學藥理研究所副教授

研究專長

  • 抗癌奈米藥物開發
  • 癌症產生抗藥性機制
  • 癌症細胞的自噬作用

指紋 查看啟用 Chun-Hei Cheung 的研究主題。這些主題標籤來自此人的作品。共同形成了獨特的指紋。

  • 3 類似的檔案
Neoplasms Medicine & Life Sciences
Aurora Kinases Medicine & Life Sciences
Autophagy Medicine & Life Sciences
Cells Chemical Compounds
cathepsin S Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Drug Resistance Medicine & Life Sciences
Patents Medicine & Life Sciences

網絡 國家層面的近期外部合作。點選圓點深入探索詳細資料。

研究計畫 2011 2018

研究成果 2009 2019

  • 2905 引文
  • 20 h-指數
  • 27 Article
  • 9 Review article
  • 3 Comment/debate

Aging-induced Akt activation involves in aging-related pathologies and Aβ-induced toxicity

Chen, Y. R., Li, Y. H., Hsieh, T. C., Wang, C. M., Cheng, K. C., Wang, L., Lin, T. Y., Cheung, C-H., Wu, C. L. & Chinag, H., 2019 八月 1, 於 : Aging Cell. 18, 4, e12989.

研究成果: Article

開啟存取
Alzheimer Disease
Pathology
Diptera
Behavioral Genetics
Amyloid Precursor Protein Secretases

Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli

Tsai, S. L., Chang, Y. C., Sarvagalla, S., Wang, S., Coumar, M. S. & Cheung, C-H., 2019 八月 1, 於 : Protein Expression and Purification. 160, p. 73-83 11 p.

研究成果: Article

Escherichia coli Proteins
Organism Cloning
Recombinant Proteins
Histidine
Proteins
Pathology
Taiwan
Medicine
Degradation
Biochemistry

Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies

Ji, X. R., Cheng, K. C., Chen, Y. R., Lin, T. Y., Cheung, C-H., Wu, C. L. & Chinag, H., 2018 三月 1, 於 : FASEB Journal. 32, 3, p. 1375-1387 13 p.

研究成果: Article

Autophagy
Pathology
Proteasome Endopeptidase Complex
Ubiquitin
Alzheimer Disease
3 引文 (Scopus)

HDAC2 and HDAC5 up-regulations modulate survivin and miR-125a-5p expressions and promote hormone therapy resistance in estrogen receptor positive breast cancer cells

Huang, W. T., Tsai, Y. H., Chen, S. H., Kuo, C. W., Kuo, Y-L., Lee, K-T., Chen, W. C., Wu, P. C., Chuang, C. Y., Cheng, S. M., Lin, C. H., Leung, E. Y., Chang, Y. C. & Cheung, C-H., 2017 十二月 13, 於 : Frontiers in Pharmacology. 8, DEC, 902.

研究成果: Article

Estrogen Receptors
Up-Regulation
Hormones
Breast Neoplasms
Tamoxifen

論文

Evaluating the potency and investigating the molecular mechanism of actions of Resveratrol in human breast cancer cells

Author: 宭卉, 林., 2016 七月 28

Supervisor: Cheung, C. (Supervisor)

Student thesis: Master's Thesis

Evaluation of the possibility of combining YM155 with Amiodarone for the future YM155-based anticancer clinical trials

Author: 如雅, 蔡., 2016 八月 1

Supervisor: Cheung, C. (Supervisor)

Student thesis: Master's Thesis

Evaluation of the potency and investigation of the molecular mechanism of actions of LCL161 in hu-man breast cancer cells

Author: 薇恩, 翁., 2017 七月 20

Supervisor: Cheung, C. (Supervisor)

Student thesis: Master's Thesis

Function evaluation and mechanistic insight of the survivin suppressant YM155 in breast cancer cells

Author: 校木, 鍾., 2019

Supervisor: Cheung, C. (Supervisor)

Student thesis: Doctoral Thesis

Investigation of the novel inter-regulatory relationship between survivin and autophagy in cancer cells

Author: 琇涵, 詹., 2015 八月 17

Supervisor: Cheung, C. (Supervisor)

Student thesis: Master's Thesis