Hung-Wei Yang

2025

Lab-on-the-Needles: A Microneedle Patch-Based Mobile Unit for Highly Sensitive Ex Vivo and In Vivo Detection of Protein Biomarkers

Hsu, Y. P., Li, N. S., Pang, H. H., Pan, Y. C., Tsai, H. P., Chen, H. C., Chen, Y. T., Weng, C. H., Kuo, S. W. & Yang, H. W., 2025 1月 28, 於: ACS nano. 19, 3, p. 3249-3264 16 p.

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2024

AI-Driven Design System for Fabrication of Inhalable Nanocatchers for Virus Capture and Neutralization

Pang, H. H., Li, N. S., Hsu, Y. P., Ju, S. P., Syu, G. D., Du, P. X., Huang, C. Y., Wei, K. C. & Yang, H. W., 2024 2月 19, 於: Advanced Healthcare Materials. 13, 5, 2302927.

研究成果: Article › 同行評審

Design single-stranded DNA aptamer of cluster of differentiation 47 protein by stochastic tunnelling-basin hopping-discrete molecular dynamics method

Yang, H. W., Ju, S. P., Hsieh, Y. T. & Yang, Y. C., 2024, 於: Journal of Biomolecular Structure and Dynamics. 42, 8, p. 3969-3982 14 p.

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Lab-in-a-Vial Rapid Test for Internet of Things-Embedded Point-of-Healthcare Protein Biomarker Detection in Bodily Fluids

Li, N. S., Hsu, Y. P., Pang, H. H., Wang, S. F., Pang, S. T., Lin, C. Y., Tsai, R. Y., Huang, C. Y., Wei, K. C. & Yang, H. W., 2024 12月 12, 於: Small. 20, 50, 2400878.

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2023

Anti-Hypertensive Property of an NO Nanoparticle in an Adenine-Induced Chronic Kidney Disease Young Rat Model

Tain, Y. L., Yang, H. W., Hou, C. Y., Chang-Chien, G. P., Lin, S. & Hsu, C. N., 2023 2月, 於: Antioxidants. 12, 2, 513.

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6 引文斯高帕斯（Scopus）

Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas

Pang, H. H., Huang, C. Y., Chen, P. Y., Li, N. S., Hsu, Y. P., Wu, J. K., Fan, H. F., Wei, K. C. & Yang, H. W., 2023 6月 13, 於: ACS nano. 17, 11, p. 10407-10422 16 p.

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15 引文斯高帕斯（Scopus）

2022

Design the RNA aptamer of PCA3 long non-coding ribonucleic acid by the coarse-grained molecular mechanics

Yang, H. W., Ju, S. P. & Tseng, T. F., 2022, 於: Journal of Biomolecular Structure and Dynamics. 40, 24, p. 13833-13847 15 p.

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1 引文斯高帕斯（Scopus）

Development of a photothermal bead-based nucleic acid amplification test (pbbNAAT) technique for a high-performance loop-mediated isothermal amplification (LAMP)–based point-of-care test (POCT)

Chen, C. Y., Yang, H. W., Hsieh, P. H., Hsieh, C. H. & Wu, M. H., 2022 11月 1, 於: Biosensors and Bioelectronics. 215, 114574.

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4 引文斯高帕斯（Scopus）

Direct Metal-Free Synthesis of Uracil- and Pentaazaphenalene-Functionalized Porous Organic Polymers via Quadruple Mannich Cyclization and Their Nucleobase Recognition Activities

Ahmed, L. R., Chuang, C. H., Lüder, J., Yang, H. W. & El-Mahdy, A. F. M., 2022 11月 22, 於: Macromolecules. 55, 22, p. 10197-10209 13 p.

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15 引文斯高帕斯（Scopus）

Microneedle patches integrated with lateral flow cassettes for blood-free chronic kidney disease point-of-care testing during a pandemic

Chen, Y. J., Hsu, Y. P., Tain, Y. L., Li, N. S., Pang, H. H., Kuo, S. W. & Yang, H. W., 2022 7月 15, 於: Biosensors and Bioelectronics. 208, 114234.

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23 引文斯高帕斯（Scopus）

Sodium Thiosulfate Improves Hypertension in Rats with Adenine-Induced Chronic Kidney Disease

Hsu, C. N., Hou, C. Y., Chang-Chien, G. P., Lin, S., Yang, H. W. & Tain, Y. L., 2022 1月, 於: Antioxidants. 11, 1, 147.

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11 引文斯高帕斯（Scopus）

2021

Glucose/Glutathione Co-triggered Tumor Hypoxia Relief and Chemodynamic Therapy to Enhance Photothermal Therapy in Bladder Cancer

Chen, W. H., Yu, K. J., Jhou, J. W., Pang, H. H., Weng, W. H., Lin, W. S. & Yang, H. W., 2021 10月 18, 於: ACS Applied Bio Materials. 4, 10, p. 7485-7496 12 p.

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19 引文斯高帕斯（Scopus）

Melatonin prevents chronic kidney disease-induced hypertension in young rat treated with adenine: Implications of gut microbiota-derived metabolites

Hsu, C. N., Yang, H. W., Hou, C. Y., Chang-Chien, G. P., Lin, S. & Tain, Y. L., 2021 8月, 於: Antioxidants. 10, 8, 1211.

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14 引文斯高帕斯（Scopus）

Rapid detection of gut microbial metabolite trimethylamine n-oxide for chronic kidney disease prevention

Chang, Y. C., Chu, Y. H., Wang, C. C., Wang, C. H., Tain, Y. L. & Yang, H. W., 2021 9月, 於: Biosensors. 11, 9, 339.

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19 引文斯高帕斯（Scopus）

2020

A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level

Pang, H. H., Ke, Y. C., Li, N. S., Chen, Y. T., Huang, C. Y., Wei, K. C. & Yang, H. W., 2020 10月 1, 於: Biosensors and Bioelectronics. 165, 112325.

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34 引文斯高帕斯（Scopus）

A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone

Hsu, Y. P., Li, N. S., Chen, Y. T., Pang, H. H., Wei, K. C. & Yang, H. W., 2020 3月 1, 於: Biosensors and Bioelectronics. 151, 111960.

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37 引文斯高帕斯（Scopus）

Instrument-Free Detection of FXYD3 Using Vial-Based Immunosensor for Earlier and Faster Urothelial Carcinoma Diagnosis

Hsu, Y. P., Yang, H. W., Li, N. S., Chen, Y. T., Pang, H. H. & Pang, S. T., 2020 4月 24, 於: ACS Sensors. 5, 4, p. 928-935 8 p.

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11 引文斯高帕斯（Scopus）

Maternal adenine-induced chronic kidney disease programs hypertension in adult male rat offspring: Implications of nitric oxide and gut microbiome derived metabolites

Hsu, C. N., Yang, H. W., Hou, C. Y., Chang-Chien, G. P., Lin, S. & Tain, Y. L., 2020 10月 1, 於: International journal of molecular sciences. 21, 19, p. 1-17 17 p., 7237.

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41 引文斯高帕斯（Scopus）

Mechanism of nanoformulated graphene oxide-mediated human neutrophil activation

Lu, Y. J., Wang, Y. H., Sahu, R. S., Chen, J. P., Dash, B. S., Chung, P. J., Yang, H. W., Chuang, E. Y. & Hwang, T. L., 2020 9月 9, 於: ACS Applied Materials and Interfaces. 12, 36, p. 40141-40152 12 p.

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25 引文斯高帕斯（Scopus）

Mobile healthcare system based on the combination of a lateral flow pad and smartphone for rapid detection of uric acid in whole blood

Li, N. S., Chen, Y. T., Hsu, Y. P., Pang, H. H., Huang, C. Y., Shiue, Y. L., Wei, K. C. & Yang, H. W., 2020 9月 15, 於: Biosensors and Bioelectronics. 164, 112309.

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45 引文斯高帕斯（Scopus）

On-skin glucose-biosensing and on-demand insulin-zinc hexamers delivery using microneedles for syringe-free diabetes management

Hsu, W. L., Huang, C. Y., Hsu, Y. P., Hwang, T. L., Chang, S. H., Wang, H. Y. J., Feng, L. Y., Tzou, S. J., Wei, K. C. & Yang, H. W., 2020 10月 15, 於: Chemical Engineering Journal. 398, 125536.

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51 引文斯高帕斯（Scopus）

Perinatal resveratrol therapy prevents hypertension programmed by maternal chronic kidney disease in adult male offspring: Implications of the gut microbiome and their metabolites

Hsu, C. N., Hou, C. Y., Chang-Chien, G. P., Lin, S., Yang, H. W. & Tain, Y. L., 2020 12月, 於: Biomedicines. 8, 12, p. 1-16 16 p., 567.

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46 引文斯高帕斯（Scopus）

2019

A colorimetric immunosensor based on self-linkable dual-nanozyme for ultrasensitive bladder cancer diagnosis and prognosis monitoring

Peng, C., Hua, M. Y., Li, N. S., Hsu, Y. P., Chen, Y. T., Chuang, C. K., Pang, S. T. & Yang, H. W., 2019 2月 1, 於: Biosensors and Bioelectronics. 126, p. 581-589 9 p.

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59 引文斯高帕斯（Scopus）

Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors

Pang, H. H., Huang, C. Y., Chou, Y. W., Lin, C. J., Zhou, Z. L., Shiue, Y. L., Wei, K. C. & Yang, H. W., 2019 5月 7, 於: Nanoscale. 11, 17, p. 8102-8109 8 p.

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36 引文斯高帕斯（Scopus）

Combined Detection of CA19-9 and MUC1 Using a Colorimetric Immunosensor Based on Magnetic Gold Nanorods for Ultrasensitive Risk Assessment of Pancreatic Cancer

Li, N. S., Lin, W. L., Hsu, Y. P., Chen, Y. T., Shiue, Y. L. & Yang, H. W., 2019 11月 18, 於: ACS Applied Bio Materials. 2, 11, p. 4847-4855 9 p.

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23 引文斯高帕斯（Scopus）

Convection-enhanced delivery of a virus-like nanotherapeutic agent with dual-modal imaging for besiegement and eradication of brain tumors

Pang, H. H., Chen, P. Y., Wei, K. C., Huang, C. W., Shiue, Y. L., Huang, C. Y. & Yang, H. W., 2019, 於: Theranostics. 9, 6, p. 1752-1763 12 p.

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47 引文斯高帕斯（Scopus）

Direct glucose detection in whole blood by colorimetric assay based on glucose oxidase-conjugated graphene oxide/MnO₂ nanozymes

Lee, P. C., Li, N. S., Hsu, Y. P., Peng, C. & Yang, H. W., 2019 4月 23, 於: The Analyst. 144, 9, p. 3038-3044 7 p.

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65 引文斯高帕斯（Scopus）

Ovalbumin-Loaded Gelation Microneedles Made of Predictive Formulation by Molecular Dynamics Simulation for Enhancement of Skin Immunization

Yang, H. W., Ju, S. P., Chen, H. Y., Cheng, Y. C. & Hsu, W. L., 2019 11月 11, 於: ACS Biomaterials Science and Engineering. 5, 11, p. 6012-6021 10 p.

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3 引文斯高帕斯（Scopus）

Predicting the Most Stable Aptamer/Target Molecule Complex Configuration Using a Stochastic-Tunnelling Basin-Hopping Discrete Molecular Dynamics Method: A Novel Global Minimum Search Method for a Biomolecule Complex

Yang, H. W., Ju, S. P. & Lin, Y. S., 2019, 於: Computational and Structural Biotechnology Journal. 17, p. 812-820 9 p.

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6 引文斯高帕斯（Scopus）

2018

Aptasensor designed via the stochastic tunneling-basin hopping method for biosensing of vascular endothelial growth factor

Yang, H. W., Ju, S. P., Cheng, C. H., Chen, Y. T., Lin, Y. S. & Pang, S. T., 2018 11月 15, 於: Biosensors and Bioelectronics. 119, p. 25-33 9 p.

研究成果: Article › 同行評審

14 引文斯高帕斯（Scopus）

Diagnosis by simplicity: An aptachip for dopamine capture and accurate detection with a dual colorimetric and fluorometric system

Lin, T. Y., Wei, K. C., Ju, S. P., Huang, C. Y. & Yang, H. W., 2018, 於: Journal of Materials Chemistry B. 6, 20, p. 3387-3394 8 p.

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15 引文斯高帕斯（Scopus）

Image-Guided Focused-Ultrasound CNS Molecular Delivery: An Implementation via Dynamic Contrast-Enhanced Magnetic-Resonance Imaging

Chai, W. Y., Chu, P. C., Tsai, C. H., Lin, C. Y., Yang, H. W., Lai, H. Y. & Liu, H. L., 2018 12月 1, 於: Scientific reports. 8, 1, 4151.

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16 引文斯高帕斯（Scopus）

Multifunctional liposomal drug delivery with dual probes of magnetic resonance and fluorescence imaging

Huang, C. L., Hsieh, W. J., Lin, C. W., Yang, H. W. & Wang, C. K., 2018 8月 1, 於: Ceramics International. 44, 11, p. 12442-12450 9 p.

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11 引文斯高帕斯（Scopus）

2017

An electrochemical biosensor to simultaneously detect VEGF and PSA for early prostate cancer diagnosis based on graphene oxide/ssDNA/PLLA nanoparticles

Pan, L. H., Kuo, S. H., Lin, T. Y., Lin, C. W., Fang, P. Y. & Yang, H. W., 2017 3月 15, 於: Biosensors and Bioelectronics. 89, p. 598-605 8 p.

研究成果: Article › 同行評審

200 引文斯高帕斯（Scopus）

Co-Delivery of Docetaxel and p44/42 MAPK siRNA Using PSMA Antibody-Conjugated BSA-PEI Layer-by-Layer Nanoparticles for Prostate Cancer Target Therapy

Pang, S. T., Lin, F. W., Chuang, C. K. & Yang, H. W., 2017 5月 1, 於: Macromolecular Bioscience. 17, 5, 1600421.

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27 引文斯高帕斯（Scopus）

Ebola Vaccination Using a DNA Vaccine Coated on PLGA-PLL/γPGA Nanoparticles Administered Using a Microneedle Patch

Yang, H. W., Ye, L., Guo, X. D., Yang, C., Compans, R. W. & Prausnitz, M. R., 2017 1月 11, 於: Advanced Healthcare Materials. 6, 1, 1600750.

研究成果: Article › 同行評審

106 引文斯高帕斯（Scopus）

Facile preparation of electroactive graphene derivative and its potential application in electrochemical detection

Chen, H. C., Yang, H. W., Yang, K. H., Chen, C. H., Hou, C. C. & Tu, Y. M., 2017 3月 1, 於: Sensors and Actuators, B: Chemical. 240, p. 1153-1159 7 p.

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11 引文斯高帕斯（Scopus）

Functional RNAs: Combined assembly and packaging in VLPs

Fang, P. Y., Ramos, L. M. G., Holguin, S. Y., Hsiao, C., Bowman, J. C., Yang, H. W. & Williams, L. D., 2017 4月 7, 於: Nucleic acids research. 45, 6, p. 3519-3527 9 p.

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40 引文斯高帕斯（Scopus）

Label-Free biochips for accurate detection of prostate cancer in the clinic: Dual biomarkers and circulating tumor cells

Pan, L. H., Pang, S. T., Fang, P. Y., Chuang, C. K. & Yang, H. W., 2017, 於: Theranostics. 7, 17, p. 4289-4300 12 p.

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15 引文斯高帕斯（Scopus）

Rapid in situ MRI traceable gel-forming dual-drug delivery for synergistic therapy of brain tumor

Lin, F. W., Chen, P. Y., Wei, K. C., Huang, C. Y., Wang, C. K. & Yang, H. W., 2017, 於: Theranostics. 7, 9, p. 2524-2536 13 p.

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26 引文斯高帕斯（Scopus）

Self-assembly DNA polyplex vaccine inside dissolving microneedles for high-potency intradermal vaccination

Liao, J. F., Lee, J. C., Lin, C. K., Wei, K. C., Chen, P. Y. & Yang, H. W., 2017, 於: Theranostics. 7, 10, p. 2593-2605 13 p.

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44 引文斯高帕斯（Scopus）

2016

1,3-bis(2-chloroethyl)-1-nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance–fluorescence imaging for tracking of chemotherapeutic agents

Wei, K. C., Lin, F. W., Huang, C. Y., Ma, C. C. M., Chen, J. Y., Feng, L. Y. & Yang, H. W., 2016 8月 23, 於: International journal of nanomedicine. 11, p. 4065-4075 11 p.

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11 引文斯高帕斯（Scopus）

Fabrication of a Nanogold-Dot Array for Rapid and Sensitive Detection of Vascular Endothelial Growth Factor in Human Serum

Yang, H. W., Tsai, R. Y., Chen, J. P., Ju, S. P., Liao, J. F., Wei, K. C., Zou, W. L. & Hua, M. Y., 2016 11月 16, 於: ACS Applied Materials and Interfaces. 8, 45, p. 30845-30852 8 p.

研究成果: Article › 同行評審

21 引文斯高帕斯（Scopus）

Non-invasive screening for early Alzheimer's disease diagnosis by a sensitively immunomagnetic biosensor

Li, S. S., Lin, C. W., Wei, K. C., Huang, C. Y., Hsu, P. H., Liu, H. L., Lu, Y. J., Lin, S. C., Yang, H. W. & Ma, C. C. M., 2016 4月 26, 於: Scientific reports. 6, 25155.

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61 引文斯高帕斯（Scopus）

2015

A reusable magnetic graphene oxide-modified biosensor for vascular endothelial growth factor detection in cancer diagnosis

Lin, C. W., Wei, K. C., Liao, S. S., Huang, C. Y., Sun, C. L., Wu, P. J., Lu, Y. J., Yang, H. W. & Ma, C. C. M., 2015 5月 5, 於: Biosensors and Bioelectronics. 67, p. 431-437 7 p.

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107 引文斯高帕斯（Scopus）

2014

Biodistribution of PEGylated graphene oxide nanoribbons and their application in cancer chemo-photothermal therapy

Lu, Y. J., Lin, C. W., Yang, H. W., Lin, K. J., Wey, S. P., Sun, C. L., Wei, K. C., Yen, T. C., Lin, C. I., Ma, C. C. M. & Chen, J. P., 2014 8月, 於: Carbon. 74, p. 83-95 13 p.

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70 引文斯高帕斯（Scopus）

Combined detection of cancer cells and a tumor biomarker using an immunomagnetic sensor for the improvement of prostate-cancer diagnosis

Yang, H. W., Lin, C. W., Hua, M. Y., Liao, S. S., Chen, Y. T., Chen, H. C., Weng, W. H., Chuang, C. K., Pang, S. T. & Ma, C. C. M., 2014 6月 11, 於: Advanced Materials. 26, 22, p. 3662-3666 5 p.

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40 引文斯高帕斯（Scopus）

Gadolinium-functionalized nanographene oxide for combined drug and microRNA delivery and magnetic resonance imaging

Yang, H. W., Huang, C. Y., Lin, C. W., Liu, H. L., Huang, C. W., Liao, S. S., Chen, P. Y., Lu, Y. J., Wei, K. C. & Ma, C. C. M., 2014 8月, 於: Biomaterials. 35, 24, p. 6534-6542 9 p.

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161 引文斯高帕斯（Scopus）

Magnetic-Composite-Modified Polycrystalline Silicon Nanowire Field-Effect Transistor for Vascular Endothelial Growth Factor Detection and Cancer Diagnosis

Chen, H-C., Qiu, J. T., Yang, F. L., Liu, Y. C., Chen, M. C., Tsai, R. Y., Yang, H. W., Lin, C. Y., Lin, C. C., Wu, T. S., Tu, Y. M., Xiao, M. C., Ho, C. H., Huang, C. C., Lai, C. S. & Hua, M. Y., 2014 10月 7, 於: Analytical Chemistry. 86, 19, p. 9443-9450 8 p.

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18 引文斯高帕斯（Scopus）

Polyethylene glycol-coated graphene oxide attenuates antigen-specific IgE production and enhanced antigen-induced T-cell reactivity in ovalbumin-sensitized BALB/c mice

Wu, H. Y., Lin, K. J., Wang, P. Y., Lin, C. W., Yang, H. W., Ma, C. C. M., Lu, Y. J. & Jan, T. R., 2014, 於: International journal of nanomedicine. 9, p. 4257-4266 10 p.

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22 引文斯高帕斯（Scopus）

楊 閎蔚

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楊閎蔚