• 5943 引文
  • 46 h-指數
1989 …2020

Research output per year

如果您對這些純文本內容做了任何改變,很快就會看到。

研究成果

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J-Y. & Liou, J. P., 2019 一月 15, 於 : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

研究成果: Article

5 引文 斯高帕斯(Scopus)

2,2′-Diphenyl-1-picrylhydrazyl radical-scavenging active components from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) hulls

Kuo, C. C., Chiang, W., Liu, G. P., Chien, Y. L., Chang, J-Y., Lee, C. K., Lo, J. M., Huang, S. L., Shih, M. C. & Kuo, Y. H., 2002 十月 9, 於 : Journal of Agricultural and Food Chemistry. 50, 21, p. 5850-5855 6 p.

研究成果: Article

69 引文 斯高帕斯(Scopus)

2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors

Chuang, H. Y., Chang, J-Y., Lai, M. J., Kuo, C. C., Lee, H. Y., Hsieh, H. P., Chen, Y. J., Chen, L. T., Pan, W. Y. & Liou, J. P., 2011 三月 7, 於 : ChemMedChem. 6, 3, p. 450-456 7 p.

研究成果: Article

12 引文 斯高帕斯(Scopus)

2-Amino and 2′-aminocombretastatin derivatives as potent antimitotic agents

Chang, J. Y., Yang, M. F., Chang, C. Y., Chen, C. M., Kuo, C. C. & Liou, J. P., 2006 十月 1, 於 : Journal of Medicinal Chemistry. 49, 21, p. 6412-6415 4 p.

研究成果: Article

43 引文 斯高帕斯(Scopus)

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 2016 一月 1, 於 : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

研究成果: Article

6 引文 斯高帕斯(Scopus)

4- And 5-aroylindoles as novel classes of potent antitubulin agents

Liou, J. P., Wu, C. Y., Hsieh, H. P., Chang, C. Y., Chen, C. M., Kuo, C. C. & Chang, J. Y., 2007 九月 6, 於 : Journal of Medicinal Chemistry. 50, 18, p. 4548-4552 5 p.

研究成果: Article

57 引文 斯高帕斯(Scopus)

5-Amino-2-Aroylquinolines as highly potent tubulin polymerization inhibitors

Nien, C. Y., Chen, Y. C., Kuo, C. C., Hsieh, H. P., Chang, C. Y., Wu, J. S., Wu, S. Y., Liou, J. P. & Chang, J-Y., 2010 三月 11, 於 : Journal of Medicinal Chemistry. 53, 5, p. 2309-2313 5 p.

研究成果: Article

63 引文 斯高帕斯(Scopus)

5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2

Lee, H. Y., Chang, J. Y., Nien, C. Y., Kuo, C. C., Shih, K. H., Wu, C. H., Chang, C. Y., Lai, W. Y. & Liou, J. P., 2011 十二月 22, 於 : Journal of Medicinal Chemistry. 54, 24, p. 8517-8525 9 p.

研究成果: Article

42 引文 斯高帕斯(Scopus)

7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents

Chang, J. Y., Hsieh, H. P., Chang, C. Y., Hsu, K. S., Chiang, Y. F., Chen, C. M., Kuo, C. C. & Liou, J. P., 2006 十一月 16, 於 : Journal of Medicinal Chemistry. 49, 23, p. 6656-6659 4 p.

研究成果: Article

61 引文 斯高帕斯(Scopus)
8 引文 斯高帕斯(Scopus)

Acquired hemophilia A: Report of two cases

Chen, Y. C., Chang, J. Y., Hsueh, E. J., Wan, H. L. & Chao, T. Y., 1998 九月 1, 於 : Chinese Medical Journal (Taipei). 61, 9, p. 538-544 7 p.

研究成果: Article

2 引文 斯高帕斯(Scopus)

Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

Lien, S. C., Wei, S. Y., Chang, S. F., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 2013 五月 1, 於 : Cellular Signalling. 25, 5, p. 1252-1263 12 p.

研究成果: Article

11 引文 斯高帕斯(Scopus)

Advances in Aurora kinase inhibitor patents

Coumar, M. S., Cheung, C-H., Chang, J-Y. & Hsieh, H. P., 2009 三月 1, 於 : Expert Opinion on Therapeutic Patents. 19, 3, p. 321-356 36 p.

研究成果: Review article

22 引文 斯高帕斯(Scopus)
71 引文 斯高帕斯(Scopus)
4 引文 斯高帕斯(Scopus)

Allergies and Risk of Head and Neck Cancer: An Original Study plus Meta-Analysis

Hsiao, J. R., Ou, C. Y., Lo, H. I., Huang, C. C., Lee, W. T., Huang, J. S., Chen, K. C., Wong, T. Y., Tsai, S. T., Yen, C. J., Wu, Y. H., Hsueh, W. T., Yang, M. W., Wu, S. Y., Chang, J. Y., Chang, K. Y., Lin, C. L., Wang, F. T., Wang, Y. H., Weng, Y. L. 及其他2, Yang, H. C. & Chang, J. S., 2013 二月 1, 於 : PloS one. 8, 2, e55138.

研究成果: Article

14 引文 斯高帕斯(Scopus)

Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer

Liao, H. C., Wu, S-Y., Ou, C-Y., Hsiao, J-R., Huang, J-S., Tsai, S-T., Huang, C-C., Wang, D-Y., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Huang, T-T., Wu, Y-H., Hsueh, W-T., Yen, C-J., Yang, M-W., Lin, F-C., Lai, Y-H., Chang, J-Y. 及其他6, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 九月 1, 於 : Cancer Causes and Control. 27, 9, p. 1105-1115 11 p.

研究成果: Article

3 引文 斯高帕斯(Scopus)

Allogeneic bone marrow transplantation for fourteen patients with severe aplastic anemia

Hsueh, E. J., Hwang, W. S., Huang, S. H., Chao, T. Y., Chang, J-Y. & Wang, C. C., 1996 四月 1, 於 : Chinese Medical Journal (Taipei). 57, 4, p. 247-253 7 p.

研究成果: Article

Alpha-fetoprotein response in advanced hepatocellular carcinoma receiving cytostatic agent

Chen, L. T., Shiah, H. S., Chao, Y., Chang, J. Y., Cheng, L. T. & Whang-Peng, J., 2009 十二月 20, 於 : Journal of Clinical Oncology. 27, 36, p. e271

研究成果: Letter

9 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells

Juang, S. H., Pan, W. Y., Kuo, C. C., Liou, J. P., Hung, Y. M., Chen, L. T., Hsieh, H. P. & Chang, J-Y., 2004 七月 15, 於 : Biochemical Pharmacology. 68, 2, p. 293-303 11 p.

研究成果: Article

17 引文 斯高帕斯(Scopus)

A novel cancer therapeutic using thrombospondin 1 in dendritic cells

Weng, T. Y., Huang, S. S., Yen, M. C., Lin, C. C., Chen, Y. L., Lin, C. M., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 二月, 於 : Molecular Therapy. 22, 2, p. 292-302 11 p.

研究成果: Article

10 引文 斯高帕斯(Scopus)
58 引文 斯高帕斯(Scopus)

A novel peroxisome proliferator-activated receptor α/γ agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells

Kao, Y. H., Hsieh, H. P., Chitlimalla, S. K., Pan, W. Y., Kuo, C. C., Tsai, Y. C., Lin, W. H., Chuang, S. E. & Chang, J. Y., 2008 二月 1, 於 : Anti-Cancer Drugs. 19, 2, p. 151-158 8 p.

研究成果: Article

6 引文 斯高帕斯(Scopus)

A Novel Synthetic Microtubule Inhibitor, MPT0B214 Exhibits Antitumor Activity in Human Tumor Cells through Mitochondria-Dependent Intrinsic Pathway

Chiang, N. J., Lin, C. I., Liou, J. P., Kuo, C. C., Chang, C. Y., Chen, L. T. & Chang, J. Y., 2013 三月 12, 於 : PloS one. 8, 3, e58953.

研究成果: Article

15 引文 斯高帕斯(Scopus)

Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes

Lee, H. Y., Chang, C. Y., Lai, M. J., Chuang, H. Y., Kuo, C. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2015 七月 23, 於 : Bioorganic and Medicinal Chemistry. 23, 15, p. 4230-4236 7 p.

研究成果: Article

15 引文 斯高帕斯(Scopus)

Antimitotic and vascular disrupting agents: 2-Hydroxy-3,4,5- trimethoxybenzophenones

Chang, C. Y., Chuang, H. Y., Lee, H. Y., Yeh, T. K., Kuo, C. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2014 四月 22, 於 : European Journal of Medicinal Chemistry. 77, p. 306-314 9 p.

研究成果: Article

7 引文 斯高帕斯(Scopus)

Antimutagenic constituents of Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity

Chen, H. H., Chiang, W., Chang, J. Y., Chien, Y. L., Lee, C. K., Liu, K. J., Cheng, Y. T., Chen, T. F., Kuo, Y. H. & Kuo, C. C., 2011 六月 22, 於 : Journal of Agricultural and Food Chemistry. 59, 12, p. 6444-6452 9 p.

研究成果: Article

37 引文 斯高帕斯(Scopus)

Antitubulin agents for the treatment of cancer - A medicinal chemistry update

Mahindroo, N., Liou, J. P., Chang, J. Y. & Hsieh, H. P., 2006 五月 1, 於 : Expert Opinion on Therapeutic Patents. 16, 5, p. 647-691 45 p.

研究成果: Review article

65 引文 斯高帕斯(Scopus)

Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91

Yeh, T. K., Li, C. M., Chen, C. P., Chuu, J. J., Huang, C. L., Wang, H. S., Shen, C. C., Lee, T. Y., Chang, C. Y., Chang, C. M., Chao, Y. S., Lin, C. T., Chang, J. Y. & Chen, C. T., 2010 二月 1, 於 : Pharmacological Research. 61, 2, p. 108-115 8 p.

研究成果: Article

11 引文 斯高帕斯(Scopus)

Antitumor Agents. 111.† New 4-Hydroxylated and 4-Halogenated Anilino Derivatives of 4'-Demethylepipodophyllotoxin as Potent Inhibitors of Human DNA Topoisomerase II

Lee, K. H., Beers, S. A., Mori, M., Wang, Z. Q., Kuo, Y. H., Li, L., Liu, S. Y., Chang, J-Y., Han, F. S. & Cheng, Y. C., 1990 一月 1, 於 : Journal of Medicinal Chemistry. 33, 5, p. 1364-1368 5 p.

研究成果: Article

107 引文 斯高帕斯(Scopus)

Antitumor Agents. 113. New 4β-Arylamino Derivatives of 4-O-Demethylepipodophyllotoxin and Related Compounds as Potent Inhibitors of Human DNA Topoisomerase II

Wang, Z. Q., Kuo, Y. H., Schnur, D., Bowen, J. P., Liu, S. Y., Han, F. S., Chang, J. Y., Cheng, Y. C. & Lee, K. H., 1990 一月 1, 於 : Journal of Medicinal Chemistry. 33, 9, p. 2660-2666 7 p.

研究成果: Article

120 引文 斯高帕斯(Scopus)
67 引文 斯高帕斯(Scopus)
13 引文 斯高帕斯(Scopus)

Antitumor AHMA linked to DNA minor groove binding agents: Synthesis and biological evaluation

Rastogi, K., Chang, J. Y., Pan, W. Y., Chen, C. H., Chou, T. C., Chen, L. T. & Su, T. L., 2002 九月 26, 於 : Journal of Medicinal Chemistry. 45, 20, p. 4485-4493 9 p.

研究成果: Article

30 引文 斯高帕斯(Scopus)

A phase i clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment John T Kung

Liu, K. J., Chao, T. Y., Chang, J. Y., Cheng, A. L., Ch'Ang, H. J., Kao, W. Y., Wu, Y. C., Yu, W. L., Chung, T. R. & Whang-Peng, J., 2016 八月 24, 於 : Journal of biomedical science. 23, 1, 64.

研究成果: Article

4 引文 斯高帕斯(Scopus)

A phase I study of weekly docetaxel, 24-hour infusion of high-dose fluorouracil/leucovorin and cisplatin in patients with advanced gastric cancer

Chen, L. T., Liu, T. W., Wu, C. W., Chung, T. R., Shiah, H. S., Jan, C. M., Ming Liu, J., Whang-Peng, J. & Chang, J-Y., 2002 十二月 1, 於 : Oncology. 63, 3, p. 239-247 9 p.

研究成果: Article

17 引文 斯高帕斯(Scopus)

Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines

Lee, H. Y., Lee, L. W., Nien, C. Y., Kuo, C. C., Lin, P. Y., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2012 一月 1, 於 : Organic and Biomolecular Chemistry. 10, 48, p. 9593-9600 8 p.

研究成果: Article

4 引文 斯高帕斯(Scopus)

Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis

Wang, Y. C., Tsai, Y. S., Huang, J. L., Lee, K. W., Kuo, C. C., Wang, C. S., Huang, A. M., Chang, J. Y., Jong, Y. J. & Lin, C. S., 2010 四月 1, 於 : Oral Oncology. 46, 4, p. 255-262 8 p.

研究成果: Article

21 引文 斯高帕斯(Scopus)

Arginine deprivation as a new treatment strategy for head and neck cancer

Huang, C. C., Tsai, S. T., Kuo, C. C., Chang, J. S., Jin, Y. T., Chang, J. Y. & Hsiao, J. R., 2012 十二月 1, 於 : Oral Oncology. 48, 12, p. 1227-1235 9 p.

研究成果: Article

14 引文 斯高帕斯(Scopus)
開啟存取

Aurora kinase inhibitor patents and agents in clinical testing: An update (2009 - 10)

Cheung, C. H. A., Coumar, M. S., Chang, J. Y. & Hsieh, H. P., 2011 六月 1, 於 : Expert Opinion on Therapeutic Patents. 21, 6, p. 857-884 28 p.

研究成果: Review article

34 引文 斯高帕斯(Scopus)

Aurora kinase inhibitors in preclinical and clinical testing

Cheung, C. H. A., Coumar, M. S., Hsieh, H. P. & Chang, J. Y., 2009 四月 1, 於 : Expert Opinion on Investigational Drugs. 18, 4, p. 379-398 20 p.

研究成果: Review article

83 引文 斯高帕斯(Scopus)
36 引文 斯高帕斯(Scopus)
18 引文 斯高帕斯(Scopus)

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2014 五月 22, 於 : Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

研究成果: Article

36 引文 斯高帕斯(Scopus)

BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities

Hu, C. B., Chen, C. P., Yeh, T. K., Song, J. S., Chang, C. Y., Chuu, J. J., Tung, F. F., Ho, P. Y., Chen, T. W., Lin, C. H., Wang, M. H., Chang, K. Y., Huang, C. L., Lin, H. L., Li, W. T., Hwang, D. R., Chern, J. H., Hwang, L. L., Chang, J. Y., Chao, Y. S. 及其他1, Chen, C. T., 2011 一月 1, 於 : Cancer Science. 102, 1, p. 182-191 10 p.

研究成果: Article

8 引文 斯高帕斯(Scopus)

BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo

Kuo, C. C., Hsieh, H. P., Pan, W. Y., Chen, C. P., Liou, J. P., Lee, S. J., Chang, Y. L., Chen, L. T., Chen, C. T. & Chang, J. Y., 2004 七月 1, 於 : Cancer Research. 64, 13, p. 4621-4628 8 p.

研究成果: Article

182 引文 斯高帕斯(Scopus)

BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells

Cheung, C. H. A., Lin, W. H., HsuJohn, J. T. A., Hour, T. C., Yeh, T. K., Ko, S., Lien, T. W., Coumar, M. S., Liu, J. F., Lai, W. Y., Shiao, H. Y., Lee, T. R., Hsieh, H. P. & Chang, J. Y., 2011 八月 24, 於 : PloS one. 6, 8, e23485.

研究成果: Article

13 引文 斯高帕斯(Scopus)

C 35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Hsieh, C. L., Tseng, M. H., Shao, Y. Y., Chang, J-Y., Kuo, C. C., Chang, C. Y. & Kuo, Y. H., 2006 十一月 1, 於 : Journal of Natural Products. 69, 11, p. 1611-1613 3 p.

研究成果: Article

14 引文 斯高帕斯(Scopus)