• 5943 引文
  • 46 h-指數
1989 …2020

Research output per year

如果您對這些純文本內容做了任何改變,很快就會看到。

研究成果

2015
18 引文 斯高帕斯(Scopus)

Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cells

Chen, C. C., Lee, K. D., Pai, M. Y., Chu, P. Y., Hsu, C. C., Chiu, C. C., Chen, L. T., Chang, J-Y., Hsiao, S. H. & Leu, Y. W., 2015 十月 13, 於 : Cancer Cell International. 15, 1, 98.

研究成果: Article

25 引文 斯高帕斯(Scopus)

Genetic polymorphisms in the prostaglandin pathway genes and risk of head and neck cancer

Lee, W-T., Huang, C-C., Chen, K-C., Wang, D-Y., Ou, C-Y., Tsai, S-T., Yen, C-J., Fang, S-Y., Lo, H. I., Wu, Y-H., Hsueh, W-T., Yang, M-W., Lin, F-C., Hsiao, J-R., Huang, J-S., Chang, J-Y., Chang, K. Y., Wu, S-Y., Lin, C. L., Wang, Y. H. 及其他3, Weng, Y. L., Yang, H. C. & Chang, JS. S., 2015 三月 1, 於 : Oral Diseases. 21, 2, p. 207-215 9 p.

研究成果: Article

1 引文 斯高帕斯(Scopus)

Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1

Yen, Y. C., Hsiao, J. R., Jiang, S. S., Chang, J. S., Wang, S. H., Shen, Y. Y., Chen, C. H., Chang, I. S., Chang, J. Y. & Chen, Y. W., 2015 一月 1, 於 : Oncotarget. 6, 39, p. 41837-41855 19 p.

研究成果: Article

14 引文 斯高帕斯(Scopus)
10 引文 斯高帕斯(Scopus)
12 引文 斯高帕斯(Scopus)

Novel Nrf2/ARE Activator, trans-Coniferylaldehyde, Induces a HO-1-Mediated Defense Mechanism through a Dual p38α/MAPKAPK-2 and PK-N3 Signaling Pathway

Chen, H. H., Wang, T. C., Lee, Y. C., Shen, P. T., Chang, J-Y., Yeh, T. K., Huang, C. H., Chang, H. H., Cheng, S. Y., Lin, C. Y., Shih, C., Chen, C. T., Liu, W. M., Chen, C. H. & Kuo, C. C., 2015 八月 14, 於 : Chemical Research in Toxicology. 28, 9, p. 1681-1692 12 p.

研究成果: Article

19 引文 斯高帕斯(Scopus)

Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model

Chang, K. M., Chen, H. H., Wang, T. C., Chen, I. L., Chen, Y. T., Yang, S. C., Chen, Y. L., Chang, H. H., Huang, C. H., Chang, J. Y., Shih, C., Kuo, C. C. & Tzeng, C. C., 2015 十二月 1, 於 : European Journal of Medicinal Chemistry. 106, p. 60-74 15 p.

研究成果: Article

11 引文 斯高帕斯(Scopus)

O6-methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

Chen, S. H., Kuo, C. C., Li, C. F., Cheung, C. H. A., Tsou, T. C., Chiang, H. C., Yang, Y. N., Chang, S. L., Lin, L. C., Pan, H. Y., Chang, K. Y. & Chang, J. Y., 2015 九月 1, 於 : International Journal of Cancer. 137, 6, p. 1291-1305 15 p.

研究成果: Article

13 引文 斯高帕斯(Scopus)

Phase i study of nanoliposomal irinotecan (PEP02) in advanced solid tumor patients

Chang, T. C., Shiah, H. S., Yang, C. H., Yeh, K. H., Cheng, A. L., Shen, B. N., Wang, Y. W., Yeh, C. G., Chiang, N. J., Chang, J. Y. & Chen, L. T., 2015 三月, 於 : Cancer Chemotherapy and Pharmacology. 75, 3, p. 579-586 8 p.

研究成果: Article

50 引文 斯高帕斯(Scopus)

YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells

Cheng, S. M., Chang, Y. C., Liu, C. Y., Lee, J. Y. C., Chan, H. H., Kuo, C. W., Lin, K. Y., Tsai, S. L., Chen, S. H., Li, C. F., Leung, E., Kanwar, J. R., Huang, C. C., Chang, J. Y. & Cheung, C. H. A., 2015 一月, 於 : British Journal of Pharmacology. 172, 1, p. 214-234 21 p.

研究成果: Article

44 引文 斯高帕斯(Scopus)
2014

A novel cancer therapeutic using thrombospondin 1 in dendritic cells

Weng, T. Y., Huang, S. S., Yen, M. C., Lin, C. C., Chen, Y. L., Lin, C. M., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 二月, 於 : Molecular Therapy. 22, 2, p. 292-302 11 p.

研究成果: Article

10 引文 斯高帕斯(Scopus)

Antimitotic and vascular disrupting agents: 2-Hydroxy-3,4,5- trimethoxybenzophenones

Chang, C. Y., Chuang, H. Y., Lee, H. Y., Yeh, T. K., Kuo, C. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2014 四月 22, 於 : European Journal of Medicinal Chemistry. 77, p. 306-314 9 p.

研究成果: Article

7 引文 斯高帕斯(Scopus)

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2014 五月 22, 於 : Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

研究成果: Article

36 引文 斯高帕斯(Scopus)

CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors

Chen, Y. P., Lin, H. J., Chen, J. S., Tsai, M. Y., Hsieh, H. P., Chang, J. Y., Chen, N. F., Chang, K. C., Huang, W. T., Su, W. C., Yang, S. T., Chang, W. C., Hung, L. Y. & Chen, T. Y., 2014 八月 1, 於 : International Journal of Cancer. 135, 3, p. 751-762 12 p.

研究成果: Article

5 引文 斯高帕斯(Scopus)
9 引文 斯高帕斯(Scopus)

Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents

Mehndiratta, S., Chiang, Y. F., Lai, M. J., Lee, H. Y., Chen, M. C., Kuo, C. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2014 九月 1, 於 : Bioorganic and Medicinal Chemistry. 22, 17, p. 4917-4923 7 p.

研究成果: Article

6 引文 斯高帕斯(Scopus)

DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model

Weng, T. Y., Yen, M. C., Huang, C. T., Hung, J. J., Chen, Y. L., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 一月 1, 於 : Gene Therapy. 21, 10, p. 888-896 9 p.

研究成果: Article

8 引文 斯高帕斯(Scopus)

Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b

Shiah, S. G., Hsiao, J. R., Chang, W. M., Chen, Y. W., Jin, Y. T., Wong, T. Y., Huang, J. S., Tsai, S. T., Hsu, Y. M., Chou, S. T., Yen, Y. C., Jiang, S. S., Shieh, Y. S., Chang, I. S., Hsiao, M. & Chang, J. Y., 2014 十二月 15, 於 : Cancer Research. 74, 24, p. 7560-7572 13 p.

研究成果: Article

60 引文 斯高帕斯(Scopus)

Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma

Fang, W. T., Fan, C. C., Li, S. M., Jang, T. H., Lin, H. P., Shih, N. Y., Chen, C. H., Wang, T. Y., Huang, S. F., Lee, A. Y. L., Liu, Y. L., Tsai, F. Y., Huang, C. T., Yang, S. J., Yen, L. J., Chuu, C. P., Chen, C. Y., Hsiung, C. A., Chang, J. Y., Wang, L. H. 及其他2, Chang, I. S. & Jiang, S. S., 2014 八月 15, 於 : International Journal of Cancer. 135, 4, p. 809-819 11 p.

研究成果: Article

21 引文 斯高帕斯(Scopus)

Gelsolin regulates cisplatin sensitivity in human head-and-neck cancer

Wang, P. W., Abedini, M. R., Yang, L. X., Ding, A. A., Figeys, D., Chang, J. Y., Tsang, B. K. & Shieh, D. B., 2014 十二月 15, 於 : International Journal of Cancer. 135, 12, p. 2760-2769 10 p.

研究成果: Article

13 引文 斯高帕斯(Scopus)

Inhibiting glucosylceramide synthase facilitates the radiosensitizing effects of vinorelbine in lung adenocarcinoma cells

Chiu, W. H., Chen, H. H. W., Chang, J. Y., Luo, S. J., Li, C. L., Chen, C. L., Su, W. C. & Lin, C. F., 2014 七月 28, 於 : Cancer Letters. 349, 2, p. 144-151 8 p.

研究成果: Article

7 引文 斯高帕斯(Scopus)

LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling

Sheu, J. J. C., Lee, C. C., Hua, C. H., Li, C. I., Lai, M. T., Lee, S. C., Cheng, J., Chen, C. M., Chan, C., Chao, S. C. C., Chen, J. Y., Chang, J. Y. & Lee, C. H., 2014 三月 13, 於 : Oncogene. 33, 11, p. 1375-1384 10 p.

研究成果: Article

31 引文 斯高帕斯(Scopus)

Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib

Tsai, A. C., Wang, C. Y., Liou, J. P., Pai, H. C., Hsiao, C. J., Chang, J. Y., Wang, J. C., Teng, C. M. & Pan, S. L., 2014 四月, 於 : Cell Death and Disease. 5, 4, e1162.

研究成果: Article

14 引文 斯高帕斯(Scopus)

Reciprocal regulation of MicroRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells

Yen, Y. C., Shiah, S. G., Chu, H. C., Hsu, Y. M., Hsiao, J. R., Chang, J. Y., Hung, W. C., Liao, C. T., Cheng, A. J., Lu, Y. C. & Chen, Y. W., 2014 一月 10, 於 : Molecular cancer. 13, 1, 6.

研究成果: Article

59 引文 斯高帕斯(Scopus)

Tea consumption and risk of head and neck cancer

Huang, C. C., Lee, W. T., Tsai, S. T., Ou, C. Y., Lo, H. I., Wong, T. Y., Fang, S. Y., Chen, K. C., Huang, J. S., Wu, J. L., Yen, C. J., Hsueh, W. T., Wu, Y. H., Yang, M. W., Lin, F. C., Chang, J. Y., Chang, K. Y., Wu, S. Y., Hsiao, J. R., Lin, C. L. 及其他4, Wang, Y. H., Weng, Y. L., Yang, H. C. & Chang, J. S., 2014 五月 5, 於 : PloS one. 9, 5, e96507.

研究成果: Article

11 引文 斯高帕斯(Scopus)

The interplay between alcohol consumption, oral hygiene, ALDH2and ADH1B in the risk of head and neck cancer

Tsai, S. T., Wong, T. Y., Ou, C. Y., Fang, S. Y., Chen, K. C., Hsiao, J. R., Huang, C. C., Lee, W. T., Lo, H. I., Huang, J. S., Wu, J. L., Yen, C. J., Hsueh, W. T., Wu, Y. H., Yang, M. W., Lin, F. C., Chang, J. Y., Chang, K. Y., Wu, S. Y., Liao, H. C. 及其他5, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C. & Chang, J. S., 2014 十一月 15, 於 : International Journal of Cancer. 135, 10, p. 2424-2436 13 p.

研究成果: Article

34 引文 斯高帕斯(Scopus)
2013

Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

Lien, S. C., Wei, S. Y., Chang, S. F., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 2013 五月 1, 於 : Cellular Signalling. 25, 5, p. 1252-1263 12 p.

研究成果: Article

11 引文 斯高帕斯(Scopus)

Allergies and Risk of Head and Neck Cancer: An Original Study plus Meta-Analysis

Hsiao, J. R., Ou, C. Y., Lo, H. I., Huang, C. C., Lee, W. T., Huang, J. S., Chen, K. C., Wong, T. Y., Tsai, S. T., Yen, C. J., Wu, Y. H., Hsueh, W. T., Yang, M. W., Wu, S. Y., Chang, J. Y., Chang, K. Y., Lin, C. L., Wang, F. T., Wang, Y. H., Weng, Y. L. 及其他2, Yang, H. C. & Chang, J. S., 2013 二月 1, 於 : PloS one. 8, 2, e55138.

研究成果: Article

14 引文 斯高帕斯(Scopus)

A Novel Synthetic Microtubule Inhibitor, MPT0B214 Exhibits Antitumor Activity in Human Tumor Cells through Mitochondria-Dependent Intrinsic Pathway

Chiang, N. J., Lin, C. I., Liou, J. P., Kuo, C. C., Chang, C. Y., Chen, L. T. & Chang, J. Y., 2013 三月 12, 於 : PloS one. 8, 3, e58953.

研究成果: Article

15 引文 斯高帕斯(Scopus)
36 引文 斯高帕斯(Scopus)

Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of akt signaling

Kuo, Y. Y., Lin, H. P., Huo, C., Su, L. C., Yang, J., Hsiao, P. H., Chiang, H. C., Chung, C. J., Wang, H. D., Chang, J. Y., Chen, Y. W. & Chuu, C. P., 2013 五月, 於 : International journal of molecular sciences. 14, 5, p. 8801-8817 17 p.

研究成果: Article

34 引文 斯高帕斯(Scopus)

Cholestane-3β, 5α, 6β-triol Suppresses Proliferation, Migration, and Invasion of Human Prostate Cancer Cells

Lin, C. Y., Huo, C., Kuo, L. K., Hiipakka, R. A., Jones, R. B., Lin, H. P., Hung, Y., Su, L. C., Tseng, J. C., Kuo, Y. Y., Wang, Y. L., Fukui, Y., Kao, Y. H., Kokontis, J. M., Yeh, C. C., Chen, L., Yang, S. D., Fu, H. H., Chen, Y. W., Tsai, K. K. C. 及其他2, Chang, J. Y. & Chuu, C. P., 2013 六月 13, 於 : PloS one. 8, 6, e65734.

研究成果: Article

30 引文 斯高帕斯(Scopus)

Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance

Chang, K. Y., Tsai, S. Y., Chen, S. H., Tsou, H. H., Yen, C. J., Liu, K. J., Fang, H. L., Wu, H. C., Chuang, B. F., Chou, S. W., Tang, C. K., Liu, S. Y., Lu, P. J., Yen, C. Y. & Chang, J. Y., 2013 七月 2, 於 : Journal of biomedical science. 20, 1, 43.

研究成果: Article

16 引文 斯高帕斯(Scopus)

Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma

Lee, C. H., Wong, T. S., Chan, J. Y. W., Lu, S. C., Lin, P., Cheng, A. J., Chen, Y. J., Chang, J. S. M., Hsiao, S. H., Leu, Y. W., Li, C. I., Hsiao, J-R. & Chang, J-Y., 2013 七月 1, 於 : Journal of Pathology. 230, 3, p. 298-309 12 p.

研究成果: Article

37 引文 斯高帕斯(Scopus)

Furanylazaindoles: Potent anticancer agents in vitro and in vivo

Lee, H. Y., Pan, S. L., Su, M. C., Liu, Y. M., Kuo, C. C., Chang, Y. T., Wu, J. S., Nien, C. Y., Mehndiratta, S., Chang, C. Y., Wu, S. Y., Lai, M. J., Chang, J-Y. & Liou, J. P., 2013 十月 31, 於 : Journal of Medicinal Chemistry. 56, 20, p. 8008-8018 11 p.

研究成果: Article

32 引文 斯高帕斯(Scopus)

Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification

Chen, C. C., Chu, C. B., Liu, K. J., Huang, C. Y. F., Chang, J. Y., Pan, W. Y., Chen, H. H., Cheng, Y. H., Lee, K. D., Chen, M. F., Kuo, C. C. & Chen, L. T., 2013 八月 30, 於 : Biochemical Pharmacology. 86, 7, p. 872-887 16 p.

研究成果: Article

23 引文 斯高帕斯(Scopus)

Investigating the association between oral hygiene and head and neck cancer

Chang, J. S., Lo, H. I., Wong, T. Y., Huang, C. C., Lee, W. T., Tsai, S. T., Chen, K. C., Yen, C. J., Wu, Y. H., Hsueh, W. T., Yang, M. W., Wu, S. Y., Chang, K. Y., Chang, J. Y., Ou, C. Y., Wang, Y. H., Weng, Y. L., Yang, H. C., Wang, F. T., Lin, C. L. 及其他2, Huang, J. S. & Hsiao, J. R., 2013 十月 1, 於 : Oral Oncology. 49, 10, p. 1010-1017 8 p.

研究成果: Article

52 引文 斯高帕斯(Scopus)

Mechanical regulation of cancer cell apoptosis and autophagy: Roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK

Lien, S. C., Chang, S. F., Lee, P. L., Wei, S. Y., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 2013 十二月 1, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 12, p. 3124-3133 10 p.

研究成果: Article

51 引文 斯高帕斯(Scopus)

Microtubule-associated histone deacetylase 6 supports the calcium store sensor STIM1 in mediating malignant cell behaviors

Chen, Y. T., Chen, Y. F., Chiu, W. T., Liu, K. Y., Liu, Y. L., Chang, J. Y., Chang, H. C. & Shen, M. R., 2013 七月 15, 於 : Cancer Research. 73, 14, p. 4500-4509 10 p.

研究成果: Article

32 引文 斯高帕斯(Scopus)

MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR

Cheng, Y. C., Liou, J. P., Kuo, C. C., Lai, W. Y., Shih, K. H., Chang, C. Y., Pan, W. Y., Tseng, T-C. & Chang, J-Y., 2013 七月 1, 於 : Molecular Cancer Therapeutics. 12, 7, p. 1202-1212 11 p.

研究成果: Article

22 引文 斯高帕斯(Scopus)

MPT0B169, a new tubulin inhibitor, inhibits cell growth and induces G2/M Arrest in nonresistant and paclitaxel-resistant cancer cells

Lee, W. H., Liu, H. E., Chang, J. Y., Liou, J. P. & Huang, H. M., 2013 九月 1, 於 : Pharmacology. 92, 1-2, p. 90-98 9 p.

研究成果: Article

15 引文 斯高帕斯(Scopus)

Randomised clinical trial: Comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma

Shiah, H. S., Chen, C. Y., Dai, C. Y., Hsiao, C. F., Lin, Y. J., Su, W. C., Chang, J. Y., Whang-Peng, J., Lin, P. W., Huang, J. D. & Chen, L. T., 2013 一月 1, 於 : Alimentary Pharmacology and Therapeutics. 37, 1, p. 62-73 12 p.

研究成果: Article

43 引文 斯高帕斯(Scopus)

Survivin - biology and potential as a therapeutic target in oncology

Antonio Cheung, C. H., Huang, C. C., Tsai, F. Y., Lee, J. Y. C., Cheng, S. M., Chang, Y. C., Huang, Y. C., Chen, S. H. & Chang, J. Y., 2013 十月 28, 於 : OncoTargets and Therapy. 6, p. 1453-1462 10 p.

研究成果: Review article

90 引文 斯高帕斯(Scopus)
2012

Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines

Lee, H. Y., Lee, L. W., Nien, C. Y., Kuo, C. C., Lin, P. Y., Chang, C. Y., Chang, J. Y. & Liou, J. P., 2012 一月 1, 於 : Organic and Biomolecular Chemistry. 10, 48, p. 9593-9600 8 p.

研究成果: Article

4 引文 斯高帕斯(Scopus)

Arginine deprivation as a new treatment strategy for head and neck cancer

Huang, C. C., Tsai, S. T., Kuo, C. C., Chang, J. S., Jin, Y. T., Chang, J. Y. & Hsiao, J. R., 2012 十二月 1, 於 : Oral Oncology. 48, 12, p. 1227-1235 9 p.

研究成果: Article

14 引文 斯高帕斯(Scopus)

Differences in the frequencies of K-ras c12-13 genotypes by gender and pathologic phenotypes in colorectal tumors measured using the allele discrimination method

Chow, L., Lin, P-C., Chang, J. S., Chu, P. Y., Lee, P. K., Chen, S. N., Cheng, Y. M., Lee, J-C., Chang, J-Y. & Liu, T. W., 2012 一月 1, 於 : Environmental and Molecular Mutagenesis. 53, 1, p. 22-31 10 p.

研究成果: Article

7 引文 斯高帕斯(Scopus)

Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma

Shih, Y. T., Wang, M. C., Peng, H. H., Chen, T. F., Chen, L., Chang, J. Y. & Chiu, J. J., 2012 三月 1, 於 : Cellular Signalling. 24, 3, p. 779-793 15 p.

研究成果: Article

13 引文 斯高帕斯(Scopus)

Targeted Casp8AP2 methylation increases drug resistance in mesenchymal stem cells and cancer cells

Lee, K. D., Pai, M. Y., Hsu, C. C., Chen, C. C., Chen, Y. L., Chu, P. Y., Lee, C. H., Chen, L. T., Chang, J-Y., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., 2012 六月 15, 於 : Biochemical and Biophysical Research Communications. 422, 4, p. 578-585 8 p.

研究成果: Article

10 引文 斯高帕斯(Scopus)