• 1254 引文
  • 17 h-指數
20032018
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研究成果 2003 2018

  • 1254 引文
  • 17 h-指數
  • 24 Article
  • 4 Review article
  • 1 Chapter
  • 1 Conference contribution
2018
2 引文 (Scopus)
KATP Channels
Palmitic Acid
Insulin
Glucose
Glyburide
6 引文 (Scopus)

Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration

Chao, R. Y., Cheng, C. H., Wu, S-N. & Chen, P., 2018 二月 1, 於 : Journal of Neurochemistry. 144, 4, p. 483-497 15 p.

研究成果: Article

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Parkinson Disease
Dopaminergic Neurons
Protein Transport
Neurons
4 引文 (Scopus)
開啟存取
Intermediate-Conductance Calcium-Activated Potassium Channels
Motor Neurons
Tretinoin
Diazoxide
Architectural Accessibility
6 引文 (Scopus)
Amino Acid Transport System X-AG
High Fat Diet
Neuronal Plasticity
Neuroglia
Hippocampus

Monitoring changes in the abundance of endogenously expressed ATP-sensitive potassium (KATP) channels in the plasma membrane using surface biotinylation

Ruan, J. S. & Chen, P., 2018 一月 1, Methods in Molecular Biology. Humana Press Inc., p. 29-36 8 p. (Methods in Molecular Biology; 卷 1684).

研究成果: Chapter

Biotinylation
KATP Channels
Cell Fractionation
Membrane Proteins
Cell Membrane
5 引文 (Scopus)
Curcumin
Insulin-Secreting Cells
Insulin
Membrane Potentials
Nicorandil
2017
4 引文 (Scopus)
Reverse Transcriptase Inhibitors
Nucleosides
Mitochondrial DNA
Nucleotides
HIV
3 引文 (Scopus)

NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic Β-cells

Wu, Y., Fortin, D. A., Cochrane, V. A., Chen, P. & Shyng, S. L., 2017 一月 1, 於 : Journal of Biological Chemistry. 292, 37, p. 15512-15524 13 p.

研究成果: Article

Potassium Channels
Leptin
N-Methyl-D-Aspartate Receptors
KATP Channels
AMP-Activated Protein Kinases
2016
17 引文 (Scopus)
Astrocytes
Neuronal Plasticity
Neurons
Cognition
Information Services
26 引文 (Scopus)
1-Methyl-4-phenylpyridinium
Mitochondrial Dynamics
Dynamins
Melatonin
Neurons
2015
12 引文 (Scopus)

Concerted trafficking regulation of Kv2.1 and KATP channels by leptin in pancreatic β-cells

Wu, Y., Shyng, S. L. & Chen, P. C., 2015 十二月 11, 於 : Journal of Biological Chemistry. 290, 50, p. 29676-29690 15 p.

研究成果: Article

KATP Channels
Leptin
Depolymerization
AMP-Activated Protein Kinases
Cell membranes
18 引文 (Scopus)

Stem cell transplantation therapy in Parkinson’s disease

Fu, M. H., Li, C. L., Lin, H. L., Chen, P., Calkins, M. J., Chang, Y. F., Cheng, P. H. & Yang, S-H., 2015 十二月 1, 於 : SpringerPlus. 4, 1, 597.

研究成果: Review article

Stem Cell Transplantation
Cell- and Tissue-Based Therapy
Parkinson Disease
Stem Cells
Central Nervous System
2014
12 引文 (Scopus)

Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP

Zhou, Q., Chen, P., Devaraneni, P. K., Martin, G. M., Olson, E. M. & Shyng, S. L., 2014 一月 1, 於 : Channels. 8, 4, p. 376-382 7 p.

研究成果: Article

KATP Channels
Carbamazepine
Adenosine Diphosphate
Bearings (structural)
Adenosine Triphosphate
2013
34 引文 (Scopus)

Carbamazepine as a novel small molecule corrector of trafficking-impaired atp-sensitive potassium channels identified in congenital hyperinsulinism

Chen, P. C., Olson, E. M., Zhou, Q., Kryukova, Y., Sampson, H. M., Thomas, D. Y. & Shyng, S. L., 2013 七月 19, 於 : Journal of Biological Chemistry. 288, 29, p. 20942-20954 13 p.

研究成果: Article

Congenital Hyperinsulinism
KATP Channels
Potassium Channels
Carbamazepine
Molecules
20 引文 (Scopus)

Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines.

Sampson, H. M., Lam, H., Chen, P. C., Zhang, D., Mottillo, C., Mirza, M., Qasim, K., Shrier, A., Shyng, S. L., Hanrahan, J. W. & Thomas, D. Y., 2013, 於 : Unknown Journal. 8

研究成果: Article

Protein Transport
Mutant Proteins
Cell Line
Alleles
Sulfonylurea Receptors
35 引文 (Scopus)
AMP-Activated Protein Kinases
Leptin
Protein Kinases
Actins
Cell membranes
29 引文 (Scopus)

Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels

Martin, G. M., Chen, P., Devaraneni, P. & Shyng, S. L., 2013 十二月 1, 於 : Frontiers in Physiology. 4 DEC, Article 386.

研究成果: Review article

KATP Channels
Congenital Hyperinsulinism
Pharmacology
Mutation
Sulfonylurea Receptors
2011
65 引文 (Scopus)

Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression

Escartin, C., Won, S. J., Malgorn, C., Auregan, G., Berman, A. E., Chen, P., Déglon, N., Johnson, J. A., Suh, S. W. & Swanson, R. A., 2011 五月 18, 於 : Journal of Neuroscience. 31, 20, p. 7392-7401 10 p.

研究成果: Article

Excitatory Amino Acid Transporter 3
Glutathione
Antioxidants
Astrocytes
Cysteine
21 引文 (Scopus)

Syntaxin 1A regulates surface expression of β-cell ATP-sensitive potassium channels

Chen, P. C., Bruederle, C. E., Gaisano, H. Y. & Shyng, S. L., 2011 三月 1, 於 : American Journal of Physiology - Cell Physiology. 300, 3, p. C506-C516

研究成果: Article

Syntaxin 1
KATP Channels
Inwardly Rectifying Potassium Channel
Insulin
Sulfonylurea Receptors
2010
32 引文 (Scopus)

Role of Hsp90 in biogenesis of the β-cell ATP-sensitive potassium channel complex

Yan, F. F., Pratt, E. B., Chen, P., Wang, F., Skach, W. R., David, L. L. & Shyng, S. L., 2010 六月 15, 於 : Molecular Biology of the Cell. 21, 12, p. 1945-1954 10 p.

研究成果: Article

KATP Channels
Sulfonylurea Receptors
Proteins
HSC70 Heat-Shock Proteins
Insulin
2009
49 引文 (Scopus)

Molecular mechanisms of psychostimulant addiction

Chen, J. C., Chen, P. & Chiang, Y. C., 2009 三月 1, 於 : Chang Gung medical journal. 32, 2, p. 148-154 7 p.

研究成果: Review article

Nucleus Accumbens
Dopamine D1 Receptors
Dopamine
Dopamine and cAMP-Regulated Phosphoprotein 32
Addictive Behavior
368 引文 (Scopus)

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

Chen, P., Vargas, M. R., Pani, A. K., Smeyne, R. J., Johnson, D. A., Kan, Y. W. & Johnson, J. A., 2009 二月 24, 於 : Proceedings of the National Academy of Sciences of the United States of America. 106, 8, p. 2933-2938 6 p.

研究成果: Article

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Antioxidant Response Elements
Astrocytes
Parkinson Disease
NF-E2 Transcription Factor
22 引文 (Scopus)
Cyclin-Dependent Kinase 5
Dopamine D3 Receptors
Autoreceptors
Dopamine
Phosphatidylinositol 3-Kinase
2008
332 引文 (Scopus)

The Nrf2-ARE pathway: An indicator and modulator of oxidative stress in neurodegeneration

Johnson, J. A., Johnson, D. A., Kraft, A. D., Calkins, M. J., Jakel, R. J., Vargas, M. R. & Chen, P., 2008 一月 1, Mitochondria and Oxidative Stress in Neurodegenerative Disorders. Blackwell Publishing Inc., p. 61-69 9 p. (Annals of the New York Academy of Sciences; 卷 1147).

研究成果: Conference contribution

NF-E2-Related Factor 2
Oxidative stress
Modulators
Oxidative Stress
Antioxidants
2007
36 引文 (Scopus)
Dopamine D3 Receptors
Dopamine D1 Receptors
Methamphetamine
Prosencephalon
Cyclic AMP Receptors
2006
10 引文 (Scopus)

Rat NPFF1 receptor-mediated signaling: functional comparison of neuropeptide FF (NPFF), FMRFamide and PFR(Tic)amide

Chen, J. C., Lee, W. H., Chen, P., Tseng, C. P. & Huang, E. Y. K., 2006 五月 1, 於 : Peptides. 27, 5, p. 1005-1014 10 p.

研究成果: Article

FMRFamide
Rats
Phosphorylation
Spinal Injections
Pheochromocytoma
2005
46 引文 (Scopus)
Methamphetamine
Dopamine and cAMP-Regulated Phosphoprotein 32
Phosphorylation
Therapeutics
Cyclin-Dependent Kinase 5
2003
40 引文 (Scopus)
Dopamine D3 Receptors
Amphetamine
Amphetamine-Related Disorders
Dopamine Agonists
Locomotion