• 1254 引文
  • 17 h-指數
20032018
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研究成果 2003 2018

  • 1254 引文
  • 17 h-指數
  • 24 Article
  • 4 Review article
  • 1 Chapter
  • 1 Conference contribution
篩選
Article
2018
2 引文 (Scopus)
KATP Channels
Palmitic Acid
Insulin
Glucose
Glyburide
6 引文 (Scopus)

Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration

Chao, R. Y., Cheng, C. H., Wu, S-N. & Chen, P., 2018 二月 1, 於 : Journal of Neurochemistry. 144, 4, p. 483-497 15 p.

研究成果: Article

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Parkinson Disease
Dopaminergic Neurons
Protein Transport
Neurons
4 引文 (Scopus)
開啟存取
Intermediate-Conductance Calcium-Activated Potassium Channels
Motor Neurons
Tretinoin
Diazoxide
Architectural Accessibility
6 引文 (Scopus)
Amino Acid Transport System X-AG
High Fat Diet
Neuronal Plasticity
Neuroglia
Hippocampus
5 引文 (Scopus)
Curcumin
Insulin-Secreting Cells
Insulin
Membrane Potentials
Nicorandil
2017
4 引文 (Scopus)
Reverse Transcriptase Inhibitors
Nucleosides
Mitochondrial DNA
Nucleotides
HIV
3 引文 (Scopus)

NMDA receptors mediate leptin signaling and regulate potassium channel trafficking in pancreatic Β-cells

Wu, Y., Fortin, D. A., Cochrane, V. A., Chen, P. & Shyng, S. L., 2017 一月 1, 於 : Journal of Biological Chemistry. 292, 37, p. 15512-15524 13 p.

研究成果: Article

Potassium Channels
Leptin
N-Methyl-D-Aspartate Receptors
KATP Channels
AMP-Activated Protein Kinases
2016
26 引文 (Scopus)
1-Methyl-4-phenylpyridinium
Mitochondrial Dynamics
Dynamins
Melatonin
Neurons
2015
12 引文 (Scopus)

Concerted trafficking regulation of Kv2.1 and KATP channels by leptin in pancreatic β-cells

Wu, Y., Shyng, S. L. & Chen, P. C., 2015 十二月 11, 於 : Journal of Biological Chemistry. 290, 50, p. 29676-29690 15 p.

研究成果: Article

KATP Channels
Leptin
Depolymerization
AMP-Activated Protein Kinases
Cell membranes
2014
12 引文 (Scopus)

Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP

Zhou, Q., Chen, P., Devaraneni, P. K., Martin, G. M., Olson, E. M. & Shyng, S. L., 2014 一月 1, 於 : Channels. 8, 4, p. 376-382 7 p.

研究成果: Article

KATP Channels
Carbamazepine
Adenosine Diphosphate
Bearings (structural)
Adenosine Triphosphate
2013
34 引文 (Scopus)

Carbamazepine as a novel small molecule corrector of trafficking-impaired atp-sensitive potassium channels identified in congenital hyperinsulinism

Chen, P. C., Olson, E. M., Zhou, Q., Kryukova, Y., Sampson, H. M., Thomas, D. Y. & Shyng, S. L., 2013 七月 19, 於 : Journal of Biological Chemistry. 288, 29, p. 20942-20954 13 p.

研究成果: Article

Congenital Hyperinsulinism
KATP Channels
Potassium Channels
Carbamazepine
Molecules
20 引文 (Scopus)

Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines.

Sampson, H. M., Lam, H., Chen, P. C., Zhang, D., Mottillo, C., Mirza, M., Qasim, K., Shrier, A., Shyng, S. L., Hanrahan, J. W. & Thomas, D. Y., 2013, 於 : Unknown Journal. 8

研究成果: Article

Protein Transport
Mutant Proteins
Cell Line
Alleles
Sulfonylurea Receptors
35 引文 (Scopus)
AMP-Activated Protein Kinases
Leptin
Protein Kinases
Actins
Cell membranes
2011
65 引文 (Scopus)

Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression

Escartin, C., Won, S. J., Malgorn, C., Auregan, G., Berman, A. E., Chen, P. C., Déglon, N., Johnson, J. A., Suh, S. W. & Swanson, R. A., 2011 五月 18, 於 : Journal of Neuroscience. 31, 20, p. 7392-7401 10 p.

研究成果: Article

Excitatory Amino Acid Transporter 3
Glutathione
Antioxidants
Astrocytes
Cysteine
21 引文 (Scopus)

Syntaxin 1A regulates surface expression of β-cell ATP-sensitive potassium channels

Chen, P. C., Bruederle, C. E., Gaisano, H. Y. & Shyng, S. L., 2011 三月 1, 於 : American Journal of Physiology - Cell Physiology. 300, 3, p. C506-C516

研究成果: Article

Syntaxin 1
KATP Channels
Inwardly Rectifying Potassium Channel
Insulin
Sulfonylurea Receptors
2010
32 引文 (Scopus)

Role of Hsp90 in biogenesis of the β-cell ATP-sensitive potassium channel complex

Yan, F. F., Pratt, E. B., Chen, P., Wang, F., Skach, W. R., David, L. L. & Shyng, S. L., 2010 六月 15, 於 : Molecular Biology of the Cell. 21, 12, p. 1945-1954 10 p.

研究成果: Article

KATP Channels
Sulfonylurea Receptors
Proteins
HSC70 Heat-Shock Proteins
Insulin
2009
368 引文 (Scopus)

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

Chen, P., Vargas, M. R., Pani, A. K., Smeyne, R. J., Johnson, D. A., Kan, Y. W. & Johnson, J. A., 2009 二月 24, 於 : Proceedings of the National Academy of Sciences of the United States of America. 106, 8, p. 2933-2938 6 p.

研究成果: Article

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Antioxidant Response Elements
Astrocytes
Parkinson Disease
NF-E2 Transcription Factor
22 引文 (Scopus)
Cyclin-Dependent Kinase 5
Dopamine D3 Receptors
Autoreceptors
Dopamine
Phosphatidylinositol 3-Kinase
2007
36 引文 (Scopus)
Dopamine D3 Receptors
Dopamine D1 Receptors
Methamphetamine
Prosencephalon
Cyclic AMP Receptors
2006
10 引文 (Scopus)

Rat NPFF1 receptor-mediated signaling: functional comparison of neuropeptide FF (NPFF), FMRFamide and PFR(Tic)amide

Chen, J. C., Lee, W. H., Chen, P., Tseng, C. P. & Huang, E. Y. K., 2006 五月 1, 於 : Peptides. 27, 5, p. 1005-1014 10 p.

研究成果: Article

FMRFamide
Rats
Phosphorylation
Spinal Injections
Pheochromocytoma
2005
46 引文 (Scopus)
Methamphetamine
Dopamine and cAMP-Regulated Phosphoprotein 32
Phosphorylation
Therapeutics
Cyclin-Dependent Kinase 5
2003
40 引文 (Scopus)
Dopamine D3 Receptors
Amphetamine
Amphetamine-Related Disorders
Dopamine Agonists
Locomotion