Po-Han Chen

2024

EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling

Hu, Z., Chen, P. H., Li, W., Krone, M., Zheng, S., Saarbach, J., Velasco, I. U., Hines, J., Liu, Y. & Crews, C. M., 2024 3月, 於: Science Advances. 10, 13, adj7251.

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7 引文斯高帕斯（Scopus）

2023

Targeted Dephosphorylation of Tau by Phosphorylation Targeting Chimeras (PhosTACs) as a Therapeutic Modality

Hu, Z., Chen, P. H., Li, W., Douglas, T., Hines, J., Liu, Y. & Crews, C. M., 2023 2月 22, 於: Journal of the American Chemical Society. 145, 7, p. 4045-4055 11 p.

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40 引文斯高帕斯（Scopus）

2022

Identification and targeting of a HES1-YAP1-CDKN1C functional interaction in fusion-negative rhabdomyosarcoma

Kovach, A. R., Oristian, K. M., Kirsch, D. G., Bentley, R. C., Cheng, C., Chen, X., Chen, P. H., Chi, J. T. A. & Linardic, C. M., 2022 10月, 於: Molecular Oncology. 16, 20, p. 3587-3605 19 p.

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3 引文斯高帕斯（Scopus）

2021

A method to culture human alveolar rhabdomyosarcoma cell lines as rhabdospheres demonstrates an enrichment in stemness and Notch signaling

Slemmons, K. K., Deel, M. D., Lin, Y. T., Oristian, K. M., Kuprasertkul, N., Genadry, K. C., Chen, P. H., Chi, J. T. A. & Linardic, C. M., 2021 2月, 於: Biology Open. 10, 2, bio050211.

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4 引文斯高帕斯（Scopus）

DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway

Lin, C. C., Yang, W. H., Lin, Y. T., Tang, X., Chen, P. H., Ding, C. K. C., Qu, D. C., Alvarez, J. V. & Chi, J. T., 2021 3月 18, 於: Oncogene. 40, 11, p. 2018-2034 17 p.

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71 引文斯高帕斯（Scopus）

Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)

Chen, P. H., Hu, Z., An, E., Okeke, I., Zheng, S., Luo, X., Gong, A., Jaime-Figueroa, S. & Crews, C. M., 2021 12月 17, 於: ACS Chemical Biology. 16, 12, p. 2808-2815 8 p.

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67 引文斯高帕斯（Scopus）

The hippo pathway effector YAP promotes ferroptosis via the E3 ligase SKP2

Yang, W. H., Lin, C. C., Wu, J., Chao, P. Y., Chen, K., Chen, P. H. & Chi, J. T., 2021 6月, 於: Molecular Cancer Research. 19, 6, p. 1005-1014 10 p.

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77 引文斯高帕斯（Scopus）

Zinc transporter ZIP7 is a novel determinant of ferroptosis

Chen, P. H., Wu, J., Xu, Y., Ding, C. K. C., Mestre, A. A., Lin, C. C., Yang, W. H. & Chi, J. T., 2021 2月, 於: Cell Death and Disease. 12, 2, 198.

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76 引文斯高帕斯（Scopus）

2020

Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment

Chen, P. H., Hu, J., Wu, J., Huynh, D. T., Smith, T. J., Pan, S., Bisnett, B. J., Smith, A. B., Lu, A., Condon, B. M., Chi, J. T. & Boyce, M., 2020 1月 16, 於: JCI Insight. 5, 1, e127751.

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12 引文斯高帕斯（Scopus）

Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism

Chen, P. H., Wu, J., Ding, C. K. C., Lin, C. C., Pan, S., Bossa, N., Xu, Y., Yang, W. H., Mathey-Prevot, B. & Chi, J. T., 2020 3月 1, 於: Cell Death and Differentiation. 27, 3, p. 1008-1022 15 p.

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205 引文斯高帕斯（Scopus）

MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis

Ding, C. K. C., Rose, J., Sun, T., Wu, J., Chen, P. H., Lin, C. C., Yang, W. H., Chen, K. Y., Lee, H., Xu, E., Tian, S., Akinwuntan, J., Zhao, J., Guan, Z., Zhou, P. & Chi, J. T., 2020 3月 1, 於: Nature Metabolism. 2, 3, p. 270-277 8 p.

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126 引文斯高帕斯（Scopus）

2017

Glycosylation of KEAP1 links nutrient sensing to redox stress signaling

Chen, P. H., Smith, T. J., Wu, J., Siesser, P. F., Bisnett, B. J., Khan, F., Hogue, M., Soderblom, E., Tang, F., Marks, J. R., Major, M. B., Swarts, B. M., Boyce, M. & Chi, J. T., 2017 8月 1, 於: EMBO Journal. 36, 15, p. 2233-2250 18 p.

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76 引文斯高帕斯（Scopus）

KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells

Chen, P. H., Chi, J. T. & Boyce, M., 2017 11月 2, 於: Molecular and Cellular Oncology. 4, 6, e1361501.

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8 引文斯高帕斯（Scopus）

2016

An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage

Inoue, M., Chen, P. H., Siecinski, S., Li, Q. J., Liu, C., Steinman, L., Gregory, S. G., Benner, E. & Shinohara, M. L., 2016 12月 1, 於: Nature Neuroscience. 19, 12, p. 1599-1609 11 p.

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69 引文斯高帕斯（Scopus）

Conditional knockout of breast carcinoma amplified sequence 2 (BCAS2) in mouse forebrain causes dendritic malformation via β-catenin

Huang, C. W., Chen, Y. W., Lin, Y. R., Chen, P. H., Chou, M. H., Lee, L. J., Wang, P. Y., Wu, J. T., Tsao, Y. P. & Chen, S. L., 2016 10月 7, 於: Scientific reports. 6, 34927.

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9 引文斯高帕斯（Scopus）

2015

BCAS2 regulates delta-notch signaling activity through Delta Pre-mRNA splicing in Drosophila wing development

Chou, M. H., Hsieh, Y. C., Huang, C. W., Chen, P. H., Chan, S. P., Tsao, Y. P., Lee, H. H., Wu, J. T. & Chen, S. L., 2015 6月 19, 於: PloS one. 10, 6, e0130706.

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11 引文斯高帕斯（Scopus）

Secreted frizzled-related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma

Kephart, J. J. G., Tiller, R. G. J., Crose, L. E. S., Slemmons, K. K., Chen, P. H., Hinson, A. R., Bentley, R. C., Chi, J. T. A. & Linardic, C. M., 2015 11月 1, 於: Clinical Cancer Research. 21, 21, p. 4868-4880 13 p.

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19 引文斯高帕斯（Scopus）

Syngeneic murine ovarian cancer model reveals that ascites enriches for ovarian cancer stem-like cells expressing membrane GRP78

Mo, L., Bachelder, R. E., Kennedy, M., Chen, P. H., Chi, J. T., Berchuck, A., Cianciolo, G. & Pizzo, S. V., 2015 3月 1, 於: Molecular cancer therapeutics. 14, 3, p. 747-756 10 p.

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39 引文斯高帕斯（Scopus）

2013

BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing

Chen, P. H., Lee, C. I., Weng, Y. T., Tarn, W. Y., Tsao, Y. P., Kuo, P. C., Hsu, P. H., Huang, C. W., Huang, C. S., Lee, H. H., Wu, J. T. & Chen, S. L., 2013 2月, 於: RNA. 19, 2, p. 208-218 11 p.

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20 引文斯高帕斯（Scopus）

2011

RssAB signaling coordinates early development of surface multicellularity in serratia marcescens

Tsai, Y. H., Wei, J. R., Lin, C. S., Chen, P. H., Huang, S., Lin, Y. C., Wei, C. F., Lu, C. C. & Lai, H. C., 2011 8月 26, 於: PloS one. 6, 8, e24154.

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9 引文斯高帕斯（Scopus）

2009

Breast cancer amplified sequence 2, a novel negative regulator of the p53 tumor suppressor

Kuo, P. C., Tsao, Y. P., Chang, H. W., Chen, P. H., Huang, C. W., Lin, S. T., Weng, Y. T., Tsai, T. C., Shieh, S. Y. & Chen, S. L., 2009 12月 1, 於: Cancer Research. 69, 23, p. 8877-8885 9 p.

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36 引文斯高帕斯（Scopus）

陳 伯翰

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陳伯翰