蔡 少正

Professor

  • 4085 引文
  • 39 h-指數
1992 …2019
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研究成果 1992 2019

2019
1 引文 (Scopus)
Fibroblast Growth Factor 9
Corpus Striatum
Huntington Disease
Oxidative stress
Oxidative Stress
1 引文 (Scopus)

Fibroblast growth factors: Potential novel targets for regenerative therapy of osteoarthritis

Chen, T. M., Chen, Y. H., Sun, H-F. & Tsai, S-J., 2019 一月 1, 於 : Chinese Journal of Physiology. 62, 1, p. 2-10 9 p.

研究成果: Review article

Fibroblast Growth Factors
Osteoarthritis
Cartilage
Therapeutics
Research

hnRNPM induces translation switch under hypoxia to promote colon cancer development

Chen, T. M., Lai, M. C., Li, Y. H., Chan, Y. L., Wu, C. H., Wang, Y. M., Chien, C. W., Huang, S. Y., Sun, H-F. & Tsai, S-J., 2019 三月 1, 於 : EBioMedicine. 41, p. 299-309 11 p.

研究成果: Article

開啟存取
Colonic Neoplasms
Genes
Switches
Carcinogenesis
Proteins
1 引文 (Scopus)

Hypoxia: The force of endometriosis

Wu, M-H., Hsiao, K. Y. & Tsai, S-J., 2019 三月 1, 於 : Journal of Obstetrics and Gynaecology Research. 45, 3, p. 532-541 10 p.

研究成果: Article

Endometriosis
Gene Regulatory Networks
Uterus
Medical Electronics
Peritoneum
1 引文 (Scopus)
Cell Hypoxia
Stromal Cells
Apoptosis
Endometriosis
Oxygen Consumption
1 引文 (Scopus)

Targeting anthrax toxin receptor 2 ameliorates endometriosis progression

Lin, S-C., Lee, H. C., Hsu, C. T., Huang, Y. H., Li, W. N., Hsu, P. L., Wu, M-H. & Tsai, S-J., 2019 一月 1, 於 : Theranostics. 9, 3, p. 620-632 13 p.

研究成果: Article

開啟存取
Endometriosis
Histone Code
Choristoma
Pathologic Processes
Stromal Cells
1 引文 (Scopus)

TYRO3: A potential therapeutic target in cancer

Hsu, P. L., Jou, J. & Tsai, S-J., 2019 二月 1, 於 : Experimental Biology and Medicine. 244, 2, p. 83-99 17 p.

研究成果: Review article

Receptor Protein-Tyrosine Kinases
Molecular biology
Neoplasms
Signal transduction
Regain
2018
3 引文 (Scopus)

Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington's Disease

Yusuf, I. O., Cheng, P. H., Chen, H. M., Chang, Y. F., Chang, C. Y., Yang, H. I., Lin, C. W., Tsai, S-J., Chuang, J-I., Wu, C-C., Huang, B-M., Sun, H-F. & Yang, S-H., 2018 八月 1, 於 : Cellular Physiology and Biochemistry. 48, 2, p. 605-617 13 p.

研究成果: Article

Fibroblast Growth Factor 9
Corpus Striatum
Huntington Disease
Cell Death
MAP Kinase Signaling System
3 引文 (Scopus)

Suppression of COUP-TFII upregulates angiogenin and promotes angiogenesis in endometriosis

Fu, J. L., Hsiao, K. Y., Lee, H. C., Li, W. N., Chang, N., Wu, M. H. & Tsai, S. J., 2018 一月 1, 於 : Human Reproduction. 33, 8, p. 1517-1527 11 p.

研究成果: Article

COUP Transcription Factor II
Endometriosis
Up-Regulation
Stromal Cells
Down-Regulation
2017
35 引文 (Scopus)

Circular RNA – New member of noncoding RNA with novel functions

Hsiao, K. Y., Sun, H-F. & Tsai, S-J., 2017 六月 1, 於 : Experimental Biology and Medicine. 242, 11, p. 1136-1141 6 p.

研究成果: Review article

Untranslated RNA
Biosynthesis
MicroRNAs
Clustered Regularly Interspaced Short Palindromic Repeats
RNA Editing
5 引文 (Scopus)

Endocrine targets of hypoxia-inducible factors

Lee, H. C. & Tsai, S-J., 2017 七月 1, 於 : Journal of Endocrinology. 234, 1, p. R53-R65

研究成果: Review article

Homeostasis
Endocrine Glands
Hormones
Physiological Phenomena
Oxygen
11 引文 (Scopus)

Epigenetic regulation of the pathological process in endometriosis

Hsiao, K. Y., Wu, M-H. & Tsai, S-J., 2017 十月 1, 於 : Reproductive Medicine and Biology. 16, 4, p. 314-319 6 p.

研究成果: Review article

Pathologic Processes
Endometriosis
Epigenomics
Histone Code
DNA Methylation
17 引文 (Scopus)

Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness

Hou, P. C., Li, Y. H., Lin, S-C., Lin, S-C., Lee, J-C., Lin, P-W., Liou, J. P., Chang, J-Y., Kuo, C. C., Liu, Y. M., Sun, H-F. & Tsai, S-J., 2017 八月 15, 於 : Cancer Research. 77, 16, p. 4305-4316 12 p.

研究成果: Article

Dual-Specificity Phosphatases
Dual Specificity Phosphatase 2
Colonic Neoplasms
Down-Regulation
Neoplasms
6 引文 (Scopus)

Hypoxia-inhibited DUSP2 expression promotes IL-6/STAT3 signaling in endometriosis

Hsiao, K. Y., Chang, N., Tsai, J. L., Lin, S-C., Tsai, S-J. & Wu, M-H., 2017 一月 1, 於 : American Journal of Reproductive Immunology. 78, 4, e12690.

研究成果: Article

Dual Specificity Phosphatase 2
Endometriosis
Interleukin-6
Stromal Cells
Bromodeoxyuridine
11 引文 (Scopus)
Dual Specificity Phosphatase 2
Interleukin-8
Colonic Neoplasms
Up-Regulation
Neoplasm Metastasis
155 引文 (Scopus)

Noncoding effects of circular RNA CCDC66 promote colon cancer growth and metastasis

Hsiao, K. Y., Lin, Y. C., Gupta, S. K., Chang, N., Yen, L., Sun, H. S. & Tsai, S. J., 2017 五月 1, 於 : Cancer Research. 77, 9, p. 2339-2350 12 p.

研究成果: Article

Colonic Neoplasms
Neoplasm Metastasis
Growth
Neoplasms
Colorectal Neoplasms
5 引文 (Scopus)
Endometriosis
Nuclear Proteins
Fertility
Mothers
Proteins
2016
28 引文 (Scopus)

Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer

Lin, S-C., Kao, C. Y., Lee, H. J., Creighton, C. J., Ittmann, M. M., Tsai, S-J., Tsai, S. Y. & Tsai, M. J., 2016 四月 25, 於 : Nature communications. 7, 11418.

研究成果: Article

metastasis
MicroRNAs
Prostatic Neoplasms
cancer
Neoplasm Metastasis
14 引文 (Scopus)

Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer

Chien, C. W., Hou, P. C., Wu, H. C., Chang, Y. L., Lin, S-C., Lin, S-C., Lin, P-W., Lee, J-C., Chang, Y. J., Sun, H-F. & Tsai, S-J., 2016 十一月 10, 於 : Oncogene. 35, 45, p. 5872-5881 10 p.

研究成果: Article

Epithelial-Mesenchymal Transition
Colonic Neoplasms
Pharmaceutical Preparations
Oncogenes
Antibodies
3 引文 (Scopus)
Fibroblast Growth Factor 9
Fibroblasts
Testis
Spermatids
Leydig Cells
2015
7 引文 (Scopus)
Human Genome
Genome
Genes
Gene
Transcription Initiation Site
20 引文 (Scopus)
Methyltransferases
Endometriosis
MicroRNAs
Messenger RNA
DNA
10 引文 (Scopus)

Endometriosis and possible inflammation markers

Wu, M-H., Hsiao, K. Y. & Tsai, S-J., 2015 八月 1, 於 : Gynecology and Minimally Invasive Therapy. 4, 3, p. 61-67 7 p.

研究成果: Review article

Endometriosis
Inflammation
Peritoneal Macrophages
Signs and Symptoms
Early Diagnosis
15 引文 (Scopus)
Fibroblast Growth Factor 9
Fibroblast Growth Factor Receptors
Cyclic AMP Response Element-Binding Protein
Heme Oxygenase-1
Oxidation-Reduction
2 引文 (Scopus)

Pathological functions of hypoxia in endometriosis

Hsiao, K. Y., Lin, S-C., Wu, M-H. & Tsai, S-J., 2015 一月 15, 於 : Frontiers in Bioscience - Elite. 7E, 2, p. 352-366 15 p.

研究成果: Article

Endometriosis
Cyclooxygenase 2
Dinoprostone
Estrogens
Genes
14 引文 (Scopus)

Pathological functions of hypoxia in endometriosis

Hsiao, K. Y., Lin, S-C., Wu, M-H. & Tsai, S-J., 2015 一月 1, 於 : Frontiers in bioscience (Elite edition). 7, p. 309-321 13 p.

研究成果: Review article

Endometriosis
Cyclooxygenase 2
Dinoprostone
Estrogens
Genes
9 引文 (Scopus)
Vascular Endothelial Growth Factor C
Neoplasms
Tumors
Lymph Nodes
Cells
12 引文 (Scopus)

The potential regulatory mechanisms of MIR-196a in huntington's disease through bioinformatic analyses

Fu, M. H., Li, C. L., Lin, H. L., Tsai, S. J., Lai, Y. Y., Chang, Y. F., Cheng, P. H., Chen, C. M. & Yang, S. H., 2015 九月 16, 於 : PloS one. 10, 9, A1247.

研究成果: Article

Huntington Disease
Bioinformatics
cytoskeleton
Computational Biology
Cytoskeleton
2014
Literature
technical literature
Gene expression
Learning
regulation
20 引文 (Scopus)
Fibroblast Growth Factor 9
fibroblast growth factors
steroidogenesis
Leydig cells
Leydig Cells
8 引文 (Scopus)

Hypoxia-induced tumor malignancy and drug resistance: Role of microRNAs

Liao, W. L., Lin, S-C., Sun, H-F. & Tsai, S-J., 2014 一月 1, 於 : Biomarkers and Genomic Medicine. 6, 1, p. 1-11 11 p.

研究成果: Review article

MicroRNAs
Drug Resistance
Tumors
Genes
Pharmaceutical Preparations
18 引文 (Scopus)
Gene Regulatory Networks
Drug Resistance
Tumors
Genes
Pharmaceutical Preparations
13 引文 (Scopus)

Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation

Chen, T. M., Shih, Y. H., Tseng, T-C., Lai, M. C., Wu, C. H., Li, Y. H., Tsai, S-J. & Sun, H-F., 2014 一月 1, 於 : Nucleic acids research. 42, 5, p. 2932-2944 13 p.

研究成果: Article

Fibroblast Growth Factor 9
Colonic Neoplasms
Proteins
Neoplasms
Messenger RNA

Roles of prostaglandin E2 in endometriosis

Hsiao, K. Y., Wu, M-H. & Tsai, S-J., 2014 一月 1, Endometriosis: Pathogenesis and Treatment. Springer Japan, 卷 9784431544210. p. 125-146 22 p.

研究成果: Chapter

Endometriosis
Dinoprostone
Dyspareunia
Dysmenorrhea
Pelvic Pain
14 引文 (Scopus)

Suppression of COUP-TFII by proinflammatory cytokines contributes to the pathogenesis of endometriosis

Lin, S. C., Li, Y. H., Wu, M. H., Chang, Y. F., Lee, D. K., Tsai, S. Y., Tsai, M. J. & Tsai, S. J., 2014 三月, 於 : Journal of Clinical Endocrinology and Metabolism. 99, 3, p. E427-E437

研究成果: Article

COUP Transcription Factor II
Endometriosis
Cytokines
Cyclooxygenase 2
Stromal Cells
2013
46 引文 (Scopus)

Atrial Identity Is Determined by a COUP-TFII Regulatory Network

Wu, S. P., Cheng, C. M., Lanz, R. B., Wang, T., Respress, J. L., Ather, S., Chen, W., Tsai, S-J., Wehrens, X. H. T., Tsai, M. J. & Tsai, S. Y., 2013 五月 28, 於 : Developmental Cell. 25, 4, p. 417-426 10 p.

研究成果: Article

Genes
Cardiac Myocytes
Atrial Function
Chromatin Immunoprecipitation
Ablation
97 引文 (Scopus)

COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis

Qin, J., Wu, S. P., Creighton, C. J., Dai, F., Xie, X., Cheng, C. M., Frolov, A., Ayala, G., Lin, X., Feng, X. H., Ittmann, M. M., Tsai, S-J., Tsai, M. J. & Tsai, S. Y., 2013 一月 10, 於 : Nature. 493, 7431, p. 236-240 5 p.

研究成果: Article

Transforming Growth Factors
Phosphoric Monoester Hydrolases
Prostate
Carcinogenesis
Growth
24 引文 (Scopus)

Human DDX3 Interacts with the HIV-1 Tat Protein to Facilitate Viral mRNA Translation

Lai, M. C., Wang, S-W., Cheng, L., Tarn, W. Y., Tsai, S-J. & Sun, H-F., 2013 七月 1, 於 : PloS one. 8, 7, e68665.

研究成果: Article

Human Immunodeficiency Virus tat Gene Products
tat Gene Products
Protein Biosynthesis
Human immunodeficiency virus 1
translation (genetics)
91 引文 (Scopus)

In silico identification of oncogenic potential of fyn-related kinase in hepatocellular carcinoma

Chen, J. S., Hung, W. S., Chan, H. H., Tsai, S. J. & Sunny Sun, H., 2013 二月 15, 於 : Bioinformatics. 29, 4, p. 420-427 8 p.

研究成果: Article

Computer Simulation
Hepatocellular Carcinoma
Phosphotransferases
Genes
Cancer
47 引文 (Scopus)

MiR-196a ameliorates phenotypes of huntington disease in cell, transgenic mouse, and induced pluripotent stem cell models

Cheng, P. H., Li, C. L., Chang, Y. F., Tsai, S-J., Lai, Y. Y., Chan, A. W. S., Chen, C. M. & Yang, S-H., 2013 八月 8, 於 : American Journal of Human Genetics. 93, 2, p. 306-312 7 p.

研究成果: Article

Induced Pluripotent Stem Cells
Huntington Disease
Transgenic Mice
Phenotype
MicroRNAs
22 引文 (Scopus)
Leiomyoma
Integrins
Cell Proliferation
Extracellular Matrix
Cell adhesion
21 引文 (Scopus)
Annexin A2
Peritoneal Macrophages
Endometriosis
Dinoprostone
Macrophages
2 引文 (Scopus)
Transcription factors
Transcription Factors
Genes
Gene expression
Pattern recognition
2012
19 引文 (Scopus)
Hypoxia-Inducible Factor 1
Endometriosis
Stromal Cells
Estrogen Receptors
Estrogens
72 引文 (Scopus)
Phosphorylation
Stromal Cells
MicroRNAs
Gene expression
Gene Expression
17 引文 (Scopus)

Vitamin D receptor 1a promotor -1521 G/C and -1012 A/G polymorphisms in polycystic ovary syndrome

Lin, M. W., Tsai, S-J., Chou, P. Y., Huang, M. F., Sun, H-F. & Wu, M-H., 2012 十二月 1, 於 : Taiwanese Journal of Obstetrics and Gynecology. 51, 4, p. 565-571 7 p.

研究成果: Article

Calcitriol Receptors
Polycystic Ovary Syndrome
Metformin
Genotype
Serum
2011
30 引文 (Scopus)
Dual Specificity Phosphatase 2
Cyclooxygenase 2
Stromal Cells
Hypoxia-Inducible Factor 1
Extracellular Signal-Regulated MAP Kinases
4 引文 (Scopus)

Inference of transcriptional regulatory network by bootstrapping patterns

Wang, H-C., Chen, Y. HS., Kao, H-Y. & Tsai, S-J., 2011 五月 1, 於 : Bioinformatics. 27, 10, p. 1422-1428 7 p., btr155.

研究成果: Article

Transcription factors
Gene Regulatory Networks
Regulatory Networks
Bootstrapping
Transcription Factors
21 引文 (Scopus)
Insulin Receptor Substrate Proteins
Polycystic Ovary Syndrome
Interleukin-6
Metformin
Viperidae
63 引文 (Scopus)
Drug Resistance
Colonic Neoplasms
Recurrence
Neoplasms
Hypoxia-Inducible Factor 1