如果您對這些純文本內容做了任何改變,很快就會看到。

研究成果 1992 2018

  • 1307 引文
  • 22 h-指數
  • 53 Article
  • 18 Patent
  • 6 Conference contribution
  • 1 Review article
篩選
Article
2018
3 引文 (Scopus)

Novel subunit vaccine with linear array epitope protect giant grouper against nervous necrosis virus infection

Lin, C. F., Jiang, H. K., Chen, N. C., Wang, T. Y. & Chen, T. Y., 2018 三月 1, 於 : Fish and Shellfish Immunology. 74, p. 551-558 8 p.

研究成果: Article

Subunit Vaccines
grouper
subunit vaccines
vaccine
Viruses
2017
2 引文 (Scopus)

Viral infection upregulates myostatin promoter activity in orange-spotted grouper (Epinephelus coioides)

Chen, Y. T., Lin, C. F., Chen, Y. M., Lo, C. E., Chen, W. E. & Chen, T. Y., 2017 十月, 於 : PloS one. 12, 10, e0186506.

研究成果: Article

Myostatin
Epinephelus coioides
myostatin
Virus Diseases
Up-Regulation
2016
Epinephelus coioides
Interferon Type I
grouper
interferons
Viruses
7 引文 (Scopus)

Analysis of interferon gamma protein expression in zebrafish (Danio rerio)

Yoon, S., Alnabulsi, A., Wang, T. Y., Lee, P. T., Chen, T. Y., Bird, S., Zou, J. & Secombes, C. J., 2016 十月 1, 於 : Fish and Shellfish Immunology. 57, p. 79-86 8 p.

研究成果: Article

interferon-gamma
Danio rerio
Interferon-gamma
protein synthesis
protein
4 引文 (Scopus)
Nodaviridae
Epinephelus coioides
Cloning
heat shock
heat stress
2015
15 引文 (Scopus)

A microfluidic system integrated with buried optical fibers for detection of Phalaenopsis orchid pathogens

Lin, C. L., Chang, W. H., Wang, C. H., Lee, C. H., Chen, T. Y., Jan, F. J. & Lee, G. B., 2015 一月 15, 於 : Biosensors and Bioelectronics. 63, p. 572-579 8 p.

研究成果: Article

Orchidaceae
Optical Fibers
Microfluidics
Pathogens
Reverse Transcription
5 引文 (Scopus)
Cordyceps
Ascomycota
Agaricales
Ribonucleotide Reductases
Herbal Medicine
45 引文 (Scopus)

Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection

Chen, N. C., Yoshimura, M., Guan, H. H., Wang, T. Y., Misumi, Y., Lin, C. C., Chuankhayan, P., Nakagawa, A., Chan, S. I., Tsukihara, T., Chen, T. Y. & Chen, C. J., 2015 一月 1, 於 : PLoS pathogens. 11, 10, e1005203.

研究成果: Article

Nodaviridae
Capsid
Virus Diseases
Arginine
Necrosis
4 引文 (Scopus)

Genome sequence of Trichoderma virens FT-333 from tropical marine climate

Kuo, H. C., Wang, T. Y., Chen, P. P., Chen, R. S. & Chen, T. Y., 2015 一月 1, 於 : FEMS Microbiology Letters. 362, 7, fnv036.

研究成果: Article

Tropical Climate
Trichoderma
Fungal Genome
Genome
Gene Ontology
5 引文 (Scopus)

Molecular cloning and characterization of orange-spotted grouper (Epinephelus coioides) CXC chemokine ligand 12

Wu, C. S., Wang, T. Y., Liu, C. F., Lin, H. P., Chen, Y. M. & Chen, T. Y., 2015 十二月 1, 於 : Fish and Shellfish Immunology. 47, 2, p. 996-1005 10 p.

研究成果: Article

Epinephelus coioides
CXC Chemokines
grouper
Cloning
chemokines
11 引文 (Scopus)

Rapid and amplification-free detection of fish pathogens by utilizing a molecular beacon-based microfluidic system

Su, Y. C., Wang, C. H., Chang, W. H., Chen, T. Y. & Lee, G. B., 2015 一月 15, 於 : Biosensors and Bioelectronics. 63, p. 196-203 8 p.

研究成果: Article

Iridovirus
Microfluidics
Pathogens
Viruses
Fish
9 引文 (Scopus)

Regulatory factors controlling muscle mass: Competition between innate immune function and anabolic signals in regulation of atrogin-1 in Atlantic salmon

Heidari, Z., Bickerdike, R., Tinsley, J., Zou, J., Wang, T. Y., Chen, T. Y. & Martin, S. A. M., 2015 十月 1, 於 : Molecular Immunology. 67, 2, p. 341-349 9 p.

研究成果: Article

Salmo salar
Interferon Type I
Insulin-Like Growth Factor I
Primary Cell Culture
Interleukin-1
2014
4 引文 (Scopus)

Development of pedigree classification using microsatellite and mitochondrial markers for giant grouper broodstock (Epinephelus lanceolatus) management in Taiwan

Kuo, H. C., Hsu, H. A., Chua, C. S., Wang, T. Y., Chen, Y. M. & Chen, T. Y., 2014 五月, 於 : Marine Drugs. 12, 5, p. 2397-2407 11 p.

研究成果: Article

Pedigree
Taiwan
Microsatellite Repeats
Disease Resistance
Inbreeding
9 引文 (Scopus)

EcVig, a novel grouper immune-gene associated with antiviral activity against NNV infection

Yeh, Y. C., Hsu, Y. J., Chen, Y. M., Lin, H. Y., Yang, H. L., Chen, T. Y. & Wang, H. C., 2014 三月 1, 於 : Developmental and Comparative Immunology. 43, 1, p. 68-75 8 p.

研究成果: Article

Virus Diseases
Antiviral Agents
Oncorhynchus mykiss
Necrosis
Viruses
27 引文 (Scopus)

Functional analysis of an orange-spotted grouper (Epinephelus coioides) interferon gene and characterisation of its expression in response to nodavirus infection

Chen, Y. M., Kuo, C. E., Chen, G. R., Kao, Y. T., Zou, J., Secombes, C. J. & Chen, T-Y., 2014 一月 1, 於 : Developmental and Comparative Immunology. 46, 2, p. 117-128 12 p.

研究成果: Article

Interferons
Infection
Genes
Cysteine
Bass
60 引文 (Scopus)

Salmonids have an extraordinary complex type I IFN system: Characterization of the IFN locus in rainbow trout oncorhynchus mykiss reveals two novel IFN subgroups

Zou, J., Gorgoglione, B., Taylor, N. G. H., Summathed, T., Lee, P. T., Panigrahi, A., Genet, C., Chen, Y. M., Chen, T. Y., Ul Hassan, M., Mughal, S. M., Boudinot, P. & Secombes, C. J., 2014 九月 1, 於 : Journal of Immunology. 193, 5, p. 2273-2286 14 p.

研究成果: Article

Salmonidae
Oncorhynchus mykiss
Poly I-C
Trout
resiquimod
2013
15 引文 (Scopus)

Detection of viruses directly from the fresh leaves of a Phalaenopsis orchid using a microfluidic system

Chang, W. H., Yang, S. Y., Lin, C. L., Wang, C. H., Li, P. C., Chen, T. Y., Jan, F. J. & Lee, G. B., 2013 十一月 1, 於 : Nanomedicine: Nanotechnology, Biology, and Medicine. 9, 8, p. 1274-1282 9 p.

研究成果: Article

Orchidaceae
Microfluidics
Viruses
Pathogens
Virus Diseases
38 引文 (Scopus)
Chlorella
Seawater
Lipids
Oils
Biomass
39 引文 (Scopus)

Rapid isolation and detection of aquaculture pathogens in an integrated microfluidic system using loop-mediated isothermal amplification

Chang, W. H., Yang, S. Y., Wang, C. H., Tsai, M. A., Wang, P. C., Chen, T-Y., Chen, S. C. & Lee, G. B., 2013 四月 1, 於 : Sensors and Actuators, B: Chemical. 180, p. 96-106 11 p.

研究成果: Article

Aquaculture
pathogens
Pathogens
Microfluidics
Amplification
2012
7 引文 (Scopus)

An automated microfluidic chip system for detection of piscine nodavirus and characterization of its potential carrier in grouper farms

Kuo, H. C., Wang, T. Y., Hsu, H. H., Lee, S. H., Chen, Y. M., Tsai, T. J., Ou, M. C., Ku, H. T., Lee, G. B. & Chen, T. Y., 2012 八月 9, 於 : PloS one. 7, 8, e42203.

研究成果: Article

Nodaviridae
Fisheries
Microfluidics
grouper
fish farms
19 引文 (Scopus)

Grouper (Epinephelus coioides) CXCR4 is expressed in response to pathogens infection and early stage of development

Lin, C. Y., Chen, Y. M., Hsu, H. H., Shiu, C. T., Kuo, H. C. & Chen, T-Y., 2012 一月 1, 於 : Developmental and Comparative Immunology. 36, 1, p. 112-120 9 p.

研究成果: Article

CCR Receptors
Necrosis
Head Kidney
Virus Diseases
Virus Replication
6 引文 (Scopus)

Identification and characterization of DSCAM isoforms isolated from orange-spotted grouper Epinephelus coioides

Yeh, Y. C., Lee, C. W., Pan, Y. W., Hsu, Y. J., Hung, H. Y., Chen, Y-M., Lin, H. Y., Chen, T-Y., Yang, H. L. & Wang, H-C., 2012 九月 1, 於 : Developmental and Comparative Immunology. 38, 1, p. 148-159 12 p.

研究成果: Article

Cell Adhesion Molecules
Down Syndrome
Protein Isoforms
Optic Nerve Injuries
Vertebrates
24 引文 (Scopus)

Nervous necrosis virus replicates following the embryo development and dual infection with iridovirus at juvenile stage in grouper

Kuo, H. C., Wang, T. Y., Hsu, H. H., Chen, P. P., Lee, S. H., Chen, Y. M., Tsai, T. J., Wang, C. K., Ku, H. T., Lee, G. B. & Chen, T. Y., 2012 四月 26, 於 : PloS one. 7, 4, e36183.

研究成果: Article

Iridovirus
grouper
Viruses
Embryonic Development
necrosis
2011
2 引文 (Scopus)

A gene delivery system based on the N-terminal domain of human topoisomerase I

Chen, Y. A., Kuo, H. C., Chen, Y. M., Huang, S. Y., Liu, Y. R., Lin, S. C., Yang, H. L. & Chen, T-Y., 2011 六月 1, 於 : Biomaterials. 32, 17, p. 4174-4184 11 p.

研究成果: Article

His-His-His-His-His-His
Gene Transfer Techniques
Type I DNA Topoisomerase
Genes
Proteins
60 引文 (Scopus)

An integrated microfluidic loop-mediated-isothermal-amplification system for rapid sample pre-treatment and detection of viruses

Wang, C. H., Lien, K. Y., Wang, T. Y., Chen, T. Y. & Lee, G. B., 2011 一月 15, 於 : Biosensors and Bioelectronics. 26, 5, p. 2045-2052 8 p.

研究成果: Article

Microfluidics
Viruses
Amplification
Gene Amplification
RNA
15 引文 (Scopus)

An oral nervous necrosis virus vaccine using Vibrio anguillarum as an expression host provides early protection

Chen, Y-M., Shih, C. H., Liu, H. C., Wu, C. L., Lin, C. C., Wang, H-C., Chen, T-Y., Yang, H. L. & Lin, J. H. Y., 2011 十一月 16, 於 : Aquaculture. 321, 1-2, p. 26-33 8 p.

研究成果: Article

Vibrio anguillarum
vaccine
mouth
virus
necrosis
3 引文 (Scopus)

Cloning of crystallin from orange-spotted grouper and characterization of its activity as potential protective agent

Chen, Y. M., Kuo, C. E., Lin, C. M., Shiea, P. S. & Chen, T-Y., 2011 一月 1, 於 : Results in Immunology. 1, 1, p. 60-69 10 p.

研究成果: Article

Protective Agents
Crystallins
Organism Cloning
Eye Proteins
Oxidative Stress
14 引文 (Scopus)

Identification of antigens for the development of a subunit vaccine against Photobacterium damselae ssp. piscicida

Ho, L. P., Han-You Lin, J., Liu, H. C., Chen, H. E., Chen, T-Y. & Yang, H. L., 2011 一月 1, 於 : Fish and Shellfish Immunology. 30, 1, p. 412-419 8 p.

研究成果: Article

Photobacterium damselae
Subunit Vaccines
subunit vaccines
vaccine
antigen
1 引文 (Scopus)
Nodaviridae
Epinephelus coioides
Functional analysis
Cloning
grouper
38 引文 (Scopus)

Real-time quantitative PCR assay for monitoring of nervous necrosis virus infection in grouper aquaculture

Kuo, H. C., Wang, T. Y., Chen, P. P., Chen, Y. M., Chuang, H. C. & Chen, T. Y., 2011 三月 1, 於 : Journal of Clinical Microbiology. 49, 3, p. 1090-1096 7 p.

研究成果: Article

Aquaculture
Virus Diseases
Real-Time Polymerase Chain Reaction
Necrosis
Viruses
54 引文 (Scopus)

The expression of two novel orange-spotted grouper (Epinephelus coioides) TNF genes in peripheral blood leukocytes, various organs, and fish larvae

Lam, F. W. S., Wu, S. Y., Lin, S. J., Lin, C. C., Chen, Y-M., Wang, H-C., Chen, T-Y., Lin, H. T. & Lin, J. H. Y., 2011 一月 1, 於 : Fish and Shellfish Immunology. 30, 2, p. 618-629 12 p.

研究成果: Article

Epinephelus coioides
tumor necrosis factors
fish larvae
tumor
Fish
2010
27 引文 (Scopus)

Cloning of an orange-spotted grouper Epinephelus coioides heat shock protein 90AB (HSP90AB) and characterization of its expression in response to nodavirus

Chen, Y. M., Kuo, C. E., Wang, T. Y., Shie, P. S., Wang, W. C., Huang, S. L., Tsai, T. J., Chen, P. P., Chen, J. C. & Chen, T-Y., 2010 一月 1, 於 : Fish and Shellfish Immunology. 28, 5-6, p. 895-904 10 p.

研究成果: Article

Nodaviridae
Epinephelus coioides
Cloning
heat shock
Heat-Shock Proteins
95 引文 (Scopus)
Vibrio
RNA Interference
Mortality
Genes
Bacterial Load
2009
23 引文 (Scopus)

A microfluidic-based system using reverse transcription polymerase chain reactions for rapid detection of aquaculture diseases

Lien, K. Y., Lee, S. H., Tsai, T. J., Chen, T-Y. & Lee, G. B., 2009 十二月 1, 於 : Microfluidics and Nanofluidics. 7, 6, p. 795-806 12 p.

研究成果: Article

Aquaculture
polymerase chain reaction
Polymerase chain reaction
Transcription
Microfluidics
2008
4 引文 (Scopus)

A comparison of the expression of immunity-related rag 1 and ikaros genes with histogenesis of the thymus in Epinephelus malabaricus (Bloch & Schneider)

Lin, J. H. Y., Lin, H. T., Lopez, C., Chen, T. Y., Chen, M. S. & Yang, H. L., 2008 二月 1, 於 : Aquaculture Research. 39, 3, p. 252-262 11 p.

研究成果: Article

Epinephelus malabaricus
immunity
polymerase chain reaction
morphogenesis
gene
4 引文 (Scopus)

Establishment and application of PCR-SSCP profile for molecular typing of Cordyceps fungi

Kuo, H. C., Su, Y. L., Yang, H. L. & Chen, T-Y., 2008 十月 1, 於 : Food Biotechnology. 22, 4, p. 311-325 15 p.

研究成果: Article

Cordyceps
Molecular Typing
Single-Stranded Conformational Polymorphism
Fungi
Polymerase Chain Reaction
61 引文 (Scopus)

Grouper Mx confers resistance to nodavirus and interacts with coat protein

Chen, Y. M., Su, Y. L., Shie, P. S., Huang, S. L., Yang, H. L. & Chen, T-Y., 2008 一月 1, 於 : Developmental and Comparative Immunology. 32, 7, p. 825-836 12 p.

研究成果: Article

Capsid Proteins
RNA Replicase
Poly I-C
Infection
Interferons
2007
14 引文 (Scopus)
Nodaviridae
Mutagenesis
Bioinformatics
RNA Interference
Computational Biology
8 引文 (Scopus)

Myostatin gene organization and nodavirus-influenced expression in orange-spotted grouper (Epinephelus coioides)

Chen, Y. M., Wei, C. Y., Chien, C. H., Chang, H. W., Huang, S. I., Yang, H. L. & Chen, T. Y., 2007 九月 1, 於 : Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 2, 3, p. 215-227 13 p.

研究成果: Article

Myostatin
Genes
Protein Precursors
Introns
Muscle
2006
67 引文 (Scopus)

Cloning of an orange-spotted grouper (Epinephelus coioides) Mx cDNA and characterisation of its expression in response to nodavirus

Chen, Y. M., Su, Y. L., Lin, J. H. Y., Yang, H. L. & Chen, T. Y., 2006 一月, 於 : Fish and Shellfish Immunology. 20, 1, p. 58-71 14 p.

研究成果: Article

Nodaviridae
Epinephelus coioides
Cloning
grouper
Organism Cloning
12 引文 (Scopus)
Cordyceps
Ophiocordyceps sinensis
single-stranded conformational polymorphism
Taiwan
Polymerase Chain Reaction
54 引文 (Scopus)

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

Lu, T. J., Lai, W. Y., Huang, C. Y. F., Hsieh, W. J., Yu, J. S., Hsieh, Y. J., Chang, W. T., Leu, T. H., Chang, W. C., Chuang, W. J., Tang, M. J., Chen, T. Y., Lu, T. L. & Lai, M. D., 2006 十二月 15, 於 : Journal of Biological Chemistry. 281, 50, p. 38405-38417 13 p.

研究成果: Article

Cell Migration Inhibition
Paxillin
Protein Tyrosine Phosphatases
Tyrosine
Phosphorylation
32 引文 (Scopus)

Vaccination with three inactivated pathogens of cobia (Rachycentron canadum) stimulates protective immunity

Lin, J. H. Y., Chen, T-Y., Chen, M. S., Chen, H. E., Chou, R. L., Chen, T. I., Su, M. S. & Yang, H. L., 2006 五月 31, 於 : Aquaculture. 255, 1-4, p. 125-132 8 p.

研究成果: Article

Rachycentron canadum
vaccination
aquarium
immunity
aquariums
2005
30 引文 (Scopus)
Cordyceps
Ophiocordyceps sinensis
single-stranded conformational polymorphism
Fungi
Polymorphism
75 引文 (Scopus)

Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening

Wu, J. C., Chen, T. Y., Yu, C. T. R., Tsai, S. J., Hsu, J. M., Tang, M. J., Chou, C. K., Lin, W. J., Yuan, C. J. & Huang, C. Y. F., 2005 三月 11, 於 : Journal of Biological Chemistry. 280, 10, p. 9013-9022 10 p.

研究成果: Article

Cell Movement
Canidae
Screening
Phosphotransferases
Collagen
60 引文 (Scopus)

Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages

Lin, C. M., Huang, S. T., Liang, Y. C., Lin, M. S., Shih, C. M., Chang, Y. C., Chen, T. Y. & Chen, C. T., 2005 八月 1, 於 : Planta Medica. 71, 8, p. 748-753 6 p.

研究成果: Article

NF-kappa B
Macrophages
Nitric Oxide Synthase Type II
Lipopolysaccharides
isovitexin
2003
48 引文 (Scopus)

Isodiospyrin as a novel human DNA topoisomerase I inhibitor

Ting, C. Y., Hsu, C. T., Hsu, H. T., Su, J. S., Chen, T. Y., Tarn, W. Y., Kuo, Y. H., Whang-Peng, J., Liu, L. F. & Hwang, J., 2003 十一月 15, 於 : Biochemical Pharmacology. 66, 10, p. 1981-1991 11 p.

研究成果: Article

Topoisomerase I Inhibitors
Type I DNA Topoisomerase
Camptothecin
DNA
Diospyros
2001
4 引文 (Scopus)

Characterization of drug resistance to VM-26 in A2780 ovarian carcinoma cells

Lin, C. M., Chen, T. Y., Wang, L. F., Hui, C. F. & Hwang, J., 2001 一月 1, 於 : Zoological Studies. 40, 1, p. 71-78 8 p.

研究成果: Article

DNA topoisomerase (ATP-hydrolysing)
drug resistance
carcinoma
cells
drugs
2000
15 引文 (Scopus)

Development of DNA delivery system using Pseudomonas exotoxin A and a DNA binding region of human DNA topoisomerase I

Chen, T. Y., Hsu, C. T., Chang, K. H., Ting, C. Y., Whang-Peng, J., Hui, C. F. & Hwang, J., 2000 一月 1, 於 : Applied Microbiology and Biotechnology. 53, 5, p. 558-567 10 p.

研究成果: Article

DNA
Genetic Therapy
Genes
Pseudomonas aeruginosa toxA protein
human TOP1 protein
57 引文 (Scopus)

Vaccination against gonadotropin-releasing hormone (GnRH) using toxin receptor-binding domain-conjugated GnRH repeats

Hsu, C. T., Ting, C. Y., Ting, C. J., Chen, T. Y., Lin, C. P., Whang-Peng, J. & Hwang, J., 2000 七月 15, 於 : Cancer Research. 60, 14, p. 3701-3705 5 p.

研究成果: Article

Gonadotropin-Releasing Hormone
Vaccination
Peptides
Antibodies
Ovarian Neoplasms