簡偉明

個人檔案

學歷

1992 美國肯塔基大學藥學院博士

經歷

1993-1994 香港中文大學生物化學系講師
1994-迄今國立成功大學醫學院藥理所副教授

研究專長

白血病藥物治療及抗藥性

指紋查看啟用 Wai-Ming Kan 的研究主題。這些主題標籤來自此人的作品。共同形成了獨特的指紋。

Prostaglandin H2 Receptors Thromboxane A2 Medicine & Life Sciences

Thromboxane A2 Medicine & Life Sciences

Platelets Chemical Compounds

Myeloid Cells Medicine & Life Sciences

Derivatives Chemical Compounds

Thromboxanes Chemical Compounds

Oxadiazoles Chemical Compounds

Steroids Medicine & Life Sciences

網絡國家層面的近期外部合作。點選圓點深入探索詳細資料。

研究計畫 1995 2014

19 已完成

建構台灣本土化生命倫理教育的模式與評量工具

Kan, W.

13-08-01 → 14-07-31

研究計畫: Research project

棘狀細胞：製備、生成之機轉研究及作為免疫冶療工具的評估

Kan, W.

09-08-01 → 10-07-31

研究計畫: Research project

血栓素/前列腺環素異雙元受體的配體合成及結合區的特性研究

Kan, W.

07-08-01 → 08-07-31

研究計畫: Research project

含苯乙基苯酮之前列腺環素剛性結構衍生物之計設與合成

Kan, W.

05-08-01 → 06-07-31

研究計畫: Research project

A Study on Change The Surface Marder during EP2、EP4 Agonists Treatment of Human Eythroleukemia Cells

Kan, W.

04-07-01 → 05-02-28

研究計畫: Research project

研究成果 1993 2017

242 引文
7 h-指數
28 Article
1 Review article

3 引文 (Scopus)

Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells

Xiao, L. Y. & Kan, W-M., 2017 一月 1, 於 : European Journal of Pharmacology. 794, p. 201-208 8 p.

研究成果: Article

Drug Resistance

Cyclic AMP

DNA

K562 Cells

Cyclic AMP-Dependent Protein Kinases

2 引文 (Scopus)

p53 modulates the effect of ribosomal protein S6 kinase1 (S6K1) on cisplatin toxicity in chronic myeloid leukemia cells

Xiao, L. Y. & Kan, W-M., 2017 五月 1, 於 : Pharmacological Research. 119, p. 443-462 20 p.

研究成果: Article

Ribosomal Protein S6

Myeloid Cells

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Cisplatin

S 6

3 引文 (Scopus)

Poly ADP-ribose polymerase inhibition suppresses cisplatin toxicity in chronic myeloid leukemia cells

Xiao, L. Y. & Kan, W-M., 2017 一月 1, 於 : Anti-Cancer Drugs. 28, 3, p. 316-321 6 p.

研究成果: Article

Poly(ADP-ribose) Polymerases

Myeloid Cells

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Cisplatin

Cell Death

4 引文 (Scopus)

Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury

Wang, S. M., Hsu, J-Y., Ko, C. Y., Chiu, N. E., Kan, W-M., Lai, M-D. & Wang, J-M., 2016 十一月 1, 於 : Molecular Neurobiology. 53, 9, p. 5912-5927 16 p.

研究成果: Article

CCAAT-Enhancer-Binding Protein-delta

Spinal Cord Injuries

Neuroglia

Astrocytes

Cicatrix

2 引文 (Scopus)

Down-regulation of superoxide dismutase 1 by PMA is involved in cell fate determination and mediated via protein kinase D2 in myeloid leukemia cells

Chen, Y. L. & Kan, W-M., 2015 七月 1, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 10, p. 2662-2675 14 p.

研究成果: Article

Myeloid Leukemia

Myeloid Cells

Down-Regulation

Cell Death

Superoxide Dismutase