22.7 A Programmable Wireless EEG Monitoring SoC with Open/Closed-Loop Optogenetic and Electrical Stimulation for Epilepsy Control

Shuenn Yuh Lee, Chieh Tsou, Peng Wei Huang, Po Hao Cheng, Chi Chung Liao, Zhan Xien Liao, Hao Yun Lee, Chou Ching Lin, Chia Hsiang Hsieh

研究成果: Conference contribution

5 引文 斯高帕斯(Scopus)

摘要

The number of studies on closed-loop detection and electrical stimulation systems [1]-[2] for efficient control of neurological disorders is increasing, because recent clinical studies have shown their efficiency and usefulness in symptom suppression. Electrical stimulation can produce enough stimulation to affect a large range of nerves. However, all nerves near the stimulus are excited and hurt, and over time, currents start to exceed acceptable limits. Therefore, optogenetic stimulation [3]-[4] has become compelling in recent years due to several advantages: (1) no artificial noise on the EEG; (2) ability to stimulate specific nerves; and (3) no injurious effects on nerves. In this study, a wireless programmable stimulating system-on-chip (WPSSoC) is reported that provides wireless open/closed-loop optogenetic and electrical stimulation to improve treatment for epilepsy suppression. The system is demonstrated on programmable stimulation parameters wirelessly controlled by a software Graphical User Interface (GUI) on a computer. Moreover, an animal experiment conducted on optogenetic tissue was successful, thereby demonstrating that the nerve injury on optogenetic stimulation is lower than that of electrical stimulation.

原文English
主出版物標題2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
發行者Institute of Electrical and Electronics Engineers Inc.
頁面372-374
頁數3
ISBN(電子)9781538685310
DOIs
出版狀態Published - 2019 三月 6
事件2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 - San Francisco, United States
持續時間: 2019 二月 172019 二月 21

出版系列

名字Digest of Technical Papers - IEEE International Solid-State Circuits Conference
2019-February
ISSN(列印)0193-6530

Conference

Conference2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
國家United States
城市San Francisco
期間19-02-1719-02-21

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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