6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii

S. C. Kuo, C. M. Teng, L. G. Lee, T. H. Chiu, T. S. Wu, S. C. Huang, J. B. Wu, T. Y. Shieh, R. J. Chang, T. C. Chou

研究成果: Article

22 引文 斯高帕斯(Scopus)

摘要

Bioassay-directed fractionation of the n-hexane extract of the stem of Rhus semialata Murr. var. roxburghii DC (Anacardiaceae) has led to the isolation of 6-pentadecylsalicylic acid. It showed antithrombin activity at 50 μg/ml in the amidolytic method. It also prolonged the clotting time in a dose-dependent manner in the clotting assay of thrombin-fibrinogen interaction.

原文English
頁(從 - 到)247-249
頁數3
期刊Planta Medica
57
發行號3
DOIs
出版狀態Published - 1991

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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    Kuo, S. C., Teng, C. M., Lee, L. G., Chiu, T. H., Wu, T. S., Huang, S. C., Wu, J. B., Shieh, T. Y., Chang, R. J., & Chou, T. C. (1991). 6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii. Planta Medica, 57(3), 247-249. https://doi.org/10.1055/s-2006-960083