尋找研究成果

搜尋結果

• Article

  Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus

  Liu, W. C., Lin, C. P., Cheng, C. P., Ho, C. H., Lan, K. L., Cheng, J. H., Yen, C. J., Cheng, P. N., Wu, I. C., Li, I. C., Chang, B. C. H., Tseng, V. S., Chiu, Y. C. & Chang, T. T., 2016 一月 1, 於: Hepatology International. 10, 1, p. 147-157 11 p.

  研究成果: Article › 同行評審

  • Hepatitis B virus
  • Quasispecies
  • Datasets
  • Nucleotides
  • Genotype
  6 引文 斯高帕斯（Scopus）

• All-oral daclatasvir plus asunaprevir for chronic hepatitis C virus (HCV) genotype 1b infection: a sub-analysis in Asian patients from the HALLMARK DUAL study

  Kao, J. H., Lee, Y. J., Heo, J., Ahn, S. H., Lim, Y. S., Peng, C. Y., Chang, T. T., Torbeyns, A., Hughes, E., Bhore, R. & Noviello, S., 2016 十月 1, 於: Liver International. 36, 10, p. 1433-1441 9 p.

  研究成果: Article › 同行評審

  • asunaprevir
  • BMS-790052
  • Chronic Hepatitis C
  • Hepacivirus
  • Genotype
  20 引文 斯高帕斯（Scopus）

• All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: A multinational, phase 3, multicohort study

  Manns, M., Pol, S., Jacobson, I. M., Marcellin, P., Gordon, S. C., Peng, C. Y., Chang, T. T., Everson, G. T., Heo, J., Gerken, G., Yoffe, B., Towner, W. J., Bourliere, M., Metivier, S., Chu, C. J., Sievert, W., Bronowicki, J. P., Thabut, D., Lee, Y. J., Kao, J. H. 及其他6, McPhee, F., Kopit, J., Mendez, P., Linaberry, M., Hughes, E. & Noviello, S., 2014, 於: The Lancet. 384, 9954, p. 1597-1605 9 p.

  研究成果: Article › 同行評審

  • asunaprevir
  • BMS-790052
  • Hepacivirus
  • Genotype
  • Ribavirin
  280 引文 斯高帕斯（Scopus）

• A locked nucleic acid clamp-mediated PCR assay for detection of a p53 codon 249 hotspot mutation in urine

  Lin, S. Y., Dhillon, V., Jain, S., Chang, T. T., Hu, C. T., Lin, Y. J., Chen, S. H., Chang, K. C., Song, W., Yu, L., Block, T. M. & Su, Y. H., 2011 九月, 於: Journal of Molecular Diagnostics. 13, 5, p. 474-484 11 p.

  研究成果: Article › 同行評審

  • locked nucleic acid
  • Codon
  • Hepatocellular Carcinoma
  • Urine
  • Polymerase Chain Reaction
  20 引文 斯高帕斯（Scopus）

• Analysis of precore/core covariances associated with viral kinetics and genotypes in hepatitis B e antigen-positive chronic hepatitis B patients

  Cheng, C. P., Lee, P. F., Liu, W. C., Wu, I. C., Chin, C. Y., Chang, T. T. & Tseng, V. S., 2012 二月 27, 於: PloS one. 7, 2, e32553.

  研究成果: Article › 同行評審

  • chronic hepatitis B
  • hepatitis B antigens
  • Hepatitis B e Antigens
  • Viruses
  • Chronic Hepatitis B
  4 引文 斯高帕斯（Scopus）

• A phase 3b study of sofosbuvir plus ribavirin in Taiwanese patients with chronic genotype 2 hepatitis C virus infection

  Kao, J. H., Chien, R. N., Chang, T. T., Peng, C. Y., Hu, T. H., Lo, G. H., Wang, H. Y., Chen, J. J., Yang, J. C., Knox, S. J., Han, L., Mo, H., Mathias, A., Brainard, D. M., Sheen, I. S., Hsu, Y. C., Chu, C. J. & Chuang, W. L., 2016 八月 1, 於: Liver International. 36, 8, p. 1101-1107 7 p.

  研究成果: Article › 同行評審

  • Sofosbuvir
  • Ribavirin
  • Hepacivirus
  • Virus Diseases
  • Genotype
  20 引文 斯高帕斯（Scopus）

• Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production

  Lin, C. C., Tsai, P., Sun, H. Y., Hsu, M. C., Lee, J. C., Wu, I. C., Tsao, C. W., Chang, T. T. & Young, K. C., 2014, 於: Journal of Hepatology. 61, 5, p. 984-993 10 p.

  研究成果: Article › 同行評審

  • Hepatovirus
  • Clusterin
  • Molecular Chaperones
  • Virion
  • Hepacivirus
  33 引文 斯高帕斯（Scopus）

• Aspartate aminotransferase to platelet ratio index and sustained virologic response are associated with progression from hepatitis c associated liver cirrhosis to hepatocellular carcinoma after treatment with pegylated interferon plus ribavirin

  Ng, K. J., Tseng, C. W., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Huang, H. T., Wu, S. F. & Tseng, K. C., 2016 八月 1, 於: Clinical Interventions in Aging. 11, p. 1035-1041 7 p.

  研究成果: Article › 同行評審

  • Sustained Virologic Response
  • Ribavirin
  • Aspartate Aminotransferases
  • Hepatitis
  • Liver Cirrhosis
  6 引文 斯高帕斯（Scopus）

• Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic hepatitis B patients receiving oral antiviral agents

  Cheng, P. N., Liu, W. C., Tsai, H. W., Wu, I. C., Chang, T. T. & Young, K. C., 2011 四月 1, 於: Journal of Medical Virology. 83, 4, p. 602-607 6 p.

  研究成果: Article › 同行評審

  • Circular DNA
  • Chronic Hepatitis B
  • Antiviral Agents
  • Histology
  • Hepatitis B virus
  41 引文 斯高帕斯（Scopus）

• Association of serum IgG N-glycome and transforming growth factor-β1 with hepatitis B virus e antigen seroconversion during entecavir therapy

  Ho, C. H., Chien, R. N., Cheng, P. N., Liu, C. K., Su, C. S., Wu, I. C., Liu, W. C., Chen, S. H. & Chang, T. T., 2014 十一月, 於: Antiviral Research. 111, p. 121-128 8 p.

  研究成果: Article › 同行評審

  • entecavir
  • Hepatitis B e Antigens
  • Seroconversion
  • Transforming Growth Factors
  • Hepatitis B virus
  6 引文 斯高帕斯（Scopus）

• Association of sustained virologic response with reduced progression to liver cirrhosis in elderly patients with chronic hepatitis C

  Tseng, C. W., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Huang, H. T., Wu, S. F. & Tseng, K. C., 2016 三月 17, 於: Clinical Interventions in Aging. 11, p. 327-334 8 p.

  研究成果: Article › 同行評審

  • Sustained Virologic Response
  • Chronic Hepatitis C
  • Liver Cirrhosis
  • Elderly
  • Interferons
  3 引文 斯高帕斯（Scopus）

• Combined transarterial embolization/ chemoembolization-based locoregional treatment with sorafenib prolongs the survival in patients with advanced hepatocellular carcinoma and preserved liver function: A propensity score matching study

  Chien, S. C., Chen, C. Y., Cheng, P. N., Liu, Y. S., Cheng, H. C., Chuang, C. H., Chang, T. T., Chiu, H. C., Lin, Y. J. & Chiu, Y. C., 2019, 於: Liver Cancer. 8, 3, p. 186-202 17 p.

  研究成果: Article › 同行評審

  • Sorafenib
  • Propensity Score
  • Hepatocellular Carcinoma
  • Survival
  • Liver
  4 引文 斯高帕斯（Scopus）

• Contrast-induced acute kidney injury among patients with chronic kidney disease undergoing imaging studies: A meta-analysis

  Lee, Y. C., Hsieh, C. C., Chang, T. T. & Li, C. Y., 2019 一月 1, 於: American Journal of Roentgenology. 213, 4, p. 728-735 8 p.

  研究成果: Article › 同行評審

  • Acute Kidney Injury
  • Chronic Renal Insufficiency
  • Meta-Analysis
  • Contrast Media
  • Glomerular Filtration Rate
  4 引文 斯高帕斯（Scopus）

• DeF-GPU: Efficient and effective deletions finding in hepatitis B viral genomic DNA using a GPU architecture

  Cheng, C. P., Lan, K. L., Liu, W. C., Chang, T. T. & Tseng, V. S., 2016 十二月 1, 於: Methods. 111, p. 56-63 8 p.

  研究成果: Article › 同行評審

  • Viral DNA
  • Hepatitis B
  • Graphics processing unit
  • DNA
  • Immune system
  4 引文 斯高帕斯（Scopus）

• Effects of tenofovir disoproxil fumarate in hepatitis B e antigen-positive patients with normal levels of alanine aminotransferase and high levels of hepatitis B virus DNA

  Chan, H. L. Y., Chan, C. K., Hui, A. J., Chan, S., Poordad, F., Chang, T. T., Mathurin, P., Flaherty, J. F., Lin, L., Corsa, A., Gaggar, A., Subramanian, G. M., McHutchison, J. G., Lee, S. & Gane, E. J., 2014 五月, 於: Gastroenterology. 146, 5, p. 1240-1248 9 p.

  研究成果: Article › 同行評審

  • Tenofovir
  • Hepatitis B e Antigens
  • Alanine Transaminase
  • Hepatitis B virus
  • Emtricitabine
  88 引文 斯高帕斯（Scopus）

• Efficacy of entecavir in chronic hepatitis B patients with persistently normal alanine aminotransferase: Randomized, double-blind, placebo-controlled study

  Tseng, K. C., Chen, C. Y., Tsai, H. W., Chang, T. T., Chuang, W. L., Hsu, P. I., Liu, W. C. & Cheng, P. N., 2014, 於: Antiviral Therapy. 19, 8, p. 755-764 10 p.

  研究成果: Article › 同行評審

  • entecavir
  • Chronic Hepatitis B
  • Alanine Transaminase
  • Placebos
  • DNA
  9 引文 斯高帕斯（Scopus）

• Efficacy of telbivudine in Taiwanese chronic hepatitis B patients compared with GLOBE extension study and predicting treatment outcome by HBV DNA kinetics at Week 24

  Hsu, C. W., Chao, Y. C., Lee, C. M., Chang, T. T. & Chen, Y. C., 2012 十二月 13, 於: BMC Gastroenterology. 12, 178.

  研究成果: Article › 同行評審

  • Telbivudine
  • Chronic Hepatitis B
  • Kinetics
  • DNA
  • Hepatitis B e Antigens
  7 引文 斯高帕斯（Scopus）

• Fully galactosyl-fucosyl-bisected IgG ₁ reduces anti-HBV efficacy and liver histological improvement

  Ho, C. H., Chen, S. H., Tsai, H. W., Wu, I. C. & Chang, T. T., 2019 三月, 於: Antiviral Research. 163, p. 1-10 10 p.

  研究成果: Article › 同行評審

  • Hepatitis B virus
  • Immunoglobulin G
  • Liver
  • Hepatitis B e Antigens
  • Acetylglucosamine
  1 引文 斯高帕斯（Scopus）

• HBsAg expression of liver correlates with histological activities and viral replication in chronic hepatitis B

  Cheng, P. N., Chiu, Y. C., Tsai, H. W., Wang, R. H., Chiu, H. C., Wu, I. C. & Chang, T. T., 2014 十一月 1, 於: Annals of Hepatology. 13, 6, p. 771-780 10 p.

  研究成果: Article › 同行評審

  開啟存取

  • Chronic Hepatitis B
  • Hepatitis B Surface Antigens
  • Liver
  • Hepatitis B e Antigens
  • Glass
  4 引文 斯高帕斯（Scopus）

• Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma

  Yen, C. J., Lin, Y. J., Yen, C. S., Tsai, H. W., Tsai, T. F., Chang, K. Y., Huang, W. C., Lin, P. W., Chiang, C. W. & Chang, T. T., 2012 七月 27, 於: PloS one. 7, 7, e41931.

  研究成果: Article › 同行評審

  • IKappaB kinase
  • hepatitis B virus X protein
  • Cell proliferation
  • Hepatitis B virus
  • vascular endothelial growth factors
  44 引文 斯高帕斯（Scopus）

• High Rates of Viral Suppression After Long-term Entecavir Treatment of Asian Patients With Hepatitis B e Antigen-Positive Chronic Hepatitis B

  Pan, C. Q., Tong, M., Kowdley, K. V., Hu, K. Q., Chang, T. T., Lai, C. L., Yoon, S. K., Lee, S. S., Cohen, D., Tang, H. & Tsai, N., 2012 九月, 於: Clinical Gastroenterology and Hepatology. 10, 9, p. 1047-1050.e1

  研究成果: Article › 同行評審

  • entecavir
  • Hepatitis B e Antigens
  • Chronic Hepatitis B
  • Safety
  • Seroconversion
  12 引文 斯高帕斯（Scopus）

• Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein

  Lee, J. W., Liao, P. C., Young, K. C., Chang, C. L., Chen, S. S. L., Chang, T. T., Lai, M. D. & Wang, S. W., 2011 十月 7, 於: Journal of Proteome Research. 10, 10, p. 4522-4534 13 p.

  研究成果: Article › 同行評審

  • Hepatitis C virus nucleocapsid protein
  • Heterogeneous-Nuclear Ribonucleoproteins
  • Cytoplasm
  • Nuclear Factor 45 Protein
  • Proteins
  30 引文 斯高帕斯（Scopus）

• Impact of increasing alanine aminotransferase levels within normal range on incident diabetes

  Wang, C. S., Chang, T. T., Yao, W. J., Wang, S. T. & Chou, P., 2012 四月, 於: Journal of the Formosan Medical Association. 111, 4, p. 201-208 8 p.

  研究成果: Article › 同行評審

  • Alanine Transaminase
  • Reference Values
  • Type 2 Diabetes Mellitus
  • Body Mass Index
  • Hepatitis C
  30 引文 斯高帕斯（Scopus）

• Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma

  Jain, S., Chen, S., Chang, K. C., Lin, Y. J., Hu, C. T., Boldbaatar, B., Hamilton, J. P., Lin, S. Y., Chang, T. T., Chen, S. H., Song, W., Meltzer, S. J., Block, T. M. & Su, Y. H., 2012 四月 20, 於: PloS one. 7, 4, e35789.

  研究成果: Article › 同行評審

  • Methylation
  • Liver
  • hepatoma
  • Genetic Markers
  • methylation
  30 引文 斯高帕斯（Scopus）

• Ledipasvir/sofosbuvir fixed-dose combination tablet in Taiwanese patients with chronic genotype 1 hepatitis C virus

  Chuang, W. L., Chien, R. N., Peng, C. Y., Chang, T. T., Lo, G. H., Sheen, I. S., Wang, H. Y., Chen, J. J., Yang, J. C., Knox, S. J., Gao, B., Garrison, K. L., Mo, H., Pang, P. S., Hsu, Y. C., Hu, T. H., Chu, C. J. & Kao, J. H., 2016 七月 1, 於: Journal of Gastroenterology and Hepatology (Australia). 31, 7, p. 1323-1329 7 p.

  研究成果: Article › 同行評審

  • sofosbuvir drug combination ledipasvir
  • Hepacivirus
  • Tablets
  • Genotype
  • Virus Diseases
  22 引文 斯高帕斯（Scopus）

• Long-term safety and tolerability of entecavir in patients with chronic hepatitis B in the rollover study ETV-901

  Manns, M. P., Akarca, U. S., Chang, T. T., Sievert, W., Yoon, S. K., Tsai, N., Min, A., Pangerl, A., Beebe, S., Yu, M. & Wongcharatrawee, S., 2012 五月 1, 於: Expert Opinion on Drug Safety. 11, 3, p. 361-368 8 p.

  研究成果: Article › 同行評審

  • entecavir
  • Chronic Hepatitis B
  • Safety
  • Alanine Transaminase
  • Nasopharyngitis
  43 引文 斯高帕斯（Scopus）

• Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma

  Jain, S., Chang, T. T., Hamilton, J. P., Lin, S. Y., Lin, Y. J., Evans, A. A., Selaru, F. M., Lin, P. W., Chen, S. H., Block, T. M., Hu, C. T., Song, W., Meltzer, S. J. & Su, Y. H., 2011 十一月 2, 於: PloS one. 6, 11, e26799.

  研究成果: Article › 同行評審

  • Methylation
  • APC Genes
  • hepatoma
  • methylation
  • Genes
  25 引文 斯高帕斯（Scopus）

• Novel nucleotide and amino acid covariation between the 5′UTR and the NS2/NS3 proteins of hepatitis C virus: Bioinformatic and functional analyses

  Sun, H. Y., Ou, N. Y., Wang, S. W., Liu, W. C., Cheng, T. F., Shr, S. J., Sun, K. T., Chang, T. T. & Young, K. C., 2011 九月 28, 於: PloS one. 6, 9, e25530.

  研究成果: Article › 同行評審

  • Hepatitis C virus NS2 protein
  • hepatitis C virus NS3 protein
  • Hepatitis C virus
  • Viruses
  • Bioinformatics
  5 引文 斯高帕斯（Scopus）

• Peginterferon alfa-2a is associated with elevations in alanine aminotransferase at the end of treatment in chronic hepatitis C patients with sustained virologic response

  Tseng, C. W., Chen, C. Y., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Lee, C. C., Wu, S. F. & Tseng, K. C., 2014 六月 17, 於: PloS one. 9, 6, e100207.

  研究成果: Article › 同行評審

  • chronic hepatitis C
  • peginterferon alfa-2a
  • Sustained Virologic Response
  • alanine transaminase
  • Chronic Hepatitis C
  5 引文 斯高帕斯（Scopus）

• Peginterferon lambda for the treatment of HBeAg-positive chronic hepatitis B: A randomized phase 2b study (LIRA-B)

  LIRA-B Study Team, 2016 五月 1, 於: Journal of Hepatology. 64, 5, p. 1011-1019 9 p.

  研究成果: Article › 同行評審

  • Hepatitis B e Antigens
  • Chronic Hepatitis B
  • Hepatitis B virus
  • Seroconversion
  • DNA
  32 引文 斯高帕斯（Scopus）

• Plasma proteome plus site-specific N-glycoprofiling for hepatobiliary carcinomas

  Chang, T. T., Cheng, J. H., Tsai, H. W., Young, K. C., Hsieh, S. Y. & Ho, C. H., 2019 七月, 於: Journal of Pathology: Clinical Research. 5, 3, p. 199-212 14 p.

  研究成果: Article › 同行評審

  開啟存取

  • Proteome
  • Complement C3
  • Carcinoma
  • Hepatocellular Carcinoma
  • Mannose
  2 引文 斯高帕斯（Scopus）

• Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase

  Ho, C. H., Chuang, H. C., Wu, I. C., Tsai, H. W., Lin, Y. J., Sun, H. Y., Young, K. C., Chiu, Y. C., Cheng, P. N., Liu, W. C., Tan, T. H. & Chang, T. T., 2016, 於: Oncotarget. 7, 31, p. 49765-49776 12 p.

  研究成果: Article › 同行評審

  • germinal center kinases
  • Hepatocellular Carcinoma
  • Phosphotransferases
  • Recurrence
  • GCK-like kinase
  3 引文 斯高帕斯（Scopus）

• Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma

  Tsai, H. W., Lin, Y. J., Wu, H. C., Chang, T. T., Wu, I. C., Cheng, P. N., Yen, C. J., Chan, S. H., Huang, W. & Su, I. J., 2016 五月 10, 於: Oncotarget. 7, 19, p. 27724-27734 11 p.

  研究成果: Article › 同行評審

  • Chronic Hepatitis B
  • Glass
  • Antiviral Agents
  • Hepatocytes
  • Hepatocellular Carcinoma
  13 引文 斯高帕斯（Scopus）

• Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis

  Ho, C. H., Chang, T. T. & Chien, R. N., 2019 十一月 1, 於: PloS one. 14, 11, e0225482.

  研究成果: Article › 同行評審

  開啟存取

  • hypergammaglobulinemia
  • Telbivudine
  • liver cirrhosis
  • Hepatitis B virus
  • Hypergammaglobulinemia

• Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease

  Liaw, Y. F., Sheen, I. S., Lee, C. M., Akarca, U. S., Papatheodoridis, G. V., Suet-Hing Wong, F., Chang, T. T., Horban, A., Wang, C., Kwan, P., Buti, M., Prieto, M., Berg, T., Kitrinos, K., Peschell, K., Mondou, E., Frederick, D., Rousseau, F. & Schiff, E. R., 2011 一月, 於: Hepatology. 53, 1, p. 62-72 11 p.

  研究成果: Article › 同行評審

  • Emtricitabine
  • entecavir
  • Tenofovir
  • Chronic Hepatitis B
  • Liver Diseases
  254 引文 斯高帕斯（Scopus）
• Conference contribution

  Discovering clinical biomarkers of chronic hepatitis B by mining mutation hotspots

  Cheng, C. P., Lee, P. F., Chin, C. Y., Liu, W. C., Wu, I. C., Chang, T. T. & Tseng, V. S., 2011 十二月 1, Proceedings - 2011 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2011. p. 51-56 6 p. 6120719. (Proceedings - 2011 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2011).

  研究成果: Conference contribution

  • Biomarkers
  • Viruses
  • Proteins
  • Amino acids
  • DNA
  2 引文 斯高帕斯（Scopus）