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2019
Cancer immunotherapy: Silencing intracellular negative immune regulators of dendritic cells
Liu, Y. H., Yeh, I. J., Lai, M. D., Liu, K. T., Kuo, P. L. & Yen, M. C., 2019 一月 1, 於: Cancers. 11, 1, 108.研究成果: Review article › 同行評審
開啟存取2 引文 斯高帕斯(Scopus) -
Erratum: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy (Oncotarget (2015) 6 (13671–13687) DOI: 10.18632/oncotarget.3701)
Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., 2019, 於: Oncotarget. 10, 60, p. 6536-6537 2 p.研究成果: Comment/debate › 同行評審
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2017
Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells
Hung, Y. H., Huang, H. L., Chen, W. C., Yen, M. C., Cho, C. Y., Weng, T. Y., Wang, C. Y., Chen, Y. L., Chen, L. T. & Lai, M. D., 2017 二月, 於: Oncology Reports. 37, 2, p. 969-978 10 p.研究成果: Article › 同行評審
8 引文 斯高帕斯(Scopus) -
Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer
Shan, Y. S., Hsu, H. P., Lai, M. D., Hung, Y. H., Wang, C. Y., Yen, M. C. & Chen, Y. L., 2017, 於: Oncology Letters. 14, 4, p. 4517-4526 10 p.研究成果: Article › 同行評審
24 引文 斯高帕斯(Scopus) -
GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis
Shahi, P., Wang, C. Y., Chou, J., Hagerling, C., Gonzalez Velozo, H., Ruderisch, A., Yu, Y., Lai, M. D. & Werb, Z., 2017 十月 5, 於: Oncogene. 36, 40, p. 5567-5575 9 p.研究成果: Article › 同行評審
19 引文 斯高帕斯(Scopus) -
Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling
Hsu, H. P., Lai, M. D., Lee, J. C., Yen, M. C., Weng, T. Y., Chen, W. C., Fang, J. H. & Chen, Y. L., 2017 十二月 1, 於: Scientific reports. 7, 1, 5823.研究成果: Article › 同行評審
19 引文 斯高帕斯(Scopus) -
PSMB5 plays a dual role in cancer development and immunosuppression
Wang, C. Y., Li, C. Y., Hsu, H. P., Cho, C. Y., Yen, M. C., Weng, T. Y., Chen, W. C., Hung, Y. H., Lee, K. T., Hung, J. H., Chen, Y. L. & Lai, M. D., 2017, 於: American Journal of Cancer Research. 7, 11, p. 2103-2120 18 p.研究成果: Article › 同行評審
11 引文 斯高帕斯(Scopus) -
Silencing of argininosuccinate lyase inhibits colorectal cancer formation
Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 2017 一月, 於: Oncology Reports. 37, 1, p. 163-170 8 p.研究成果: Article › 同行評審
8 引文 斯高帕斯(Scopus) -
Skin Delivery of Clec4a Small Hairpin RNA Elicited an Effective Antitumor Response by Enhancing CD8+ Immunity In Vivo
Weng, T. Y., Li, C. J., Li, C. Y., Hung, Y. H., Yen, M. C., Chang, Y. W., Chen, Y. H., Chen, Y. L., Hsu, H. P., Chang, J. Y. & Lai, M. D., 2017 十二月, 於: Molecular Therapy - Nucleic Acids. 9, p. 419-427 9 p.研究成果: Article › 同行評審
4 引文 斯高帕斯(Scopus) -
Systematic analysis of the achaete-scute complex-like gene signature in clinical cancer patients
Wang, C. Y., Shahi, P., Huang, J. T. W., Phan, N. N., Sun, Z., Lin, Y. C., Lai, M. D. & Werb, Z., 2017 一月 1, 於: Molecular and Clinical Oncology. 6, 1, p. 7-18 12 p.研究成果: Article › 同行評審
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Voltage-gated calcium channels: Novel targets for cancer therapy
Phan, N. N., Wang, C. Y., Chen, C. F., Sun, Z., Lai, M. D. & Lin, Y. C., 2017, 於: Oncology Letters. 14, 2, p. 2059-2074 16 p.研究成果: Article › 同行評審
39 引文 斯高帕斯(Scopus) -
ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression
Shahi, P., Wang, C. Y., Lawson, D. A., Slorach, E. M., Lu, A., Yu, Y., Lai, M. D., Velozo, H. G. & Werb, Z., 2017 三月 21, 於: Proceedings of the National Academy of Sciences of the United States of America. 114, 12, p. 3169-3174 6 p.研究成果: Article › 同行評審
9 引文 斯高帕斯(Scopus) -
2016
Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury
Wang, S. M., Hsu, J. Y. C., Ko, C. Y., Chiu, N. E., Kan, W. M., Lai, M. D. & Wang, J. M., 2016 十一月 1, 於: Molecular Neurobiology. 53, 9, p. 5912-5927 16 p.研究成果: Article › 同行評審
10 引文 斯高帕斯(Scopus) -
Cancer stem cell marker CD90 inhibits ovarian cancer formation via β3 integrin
Chen, W. C., Hsu, H. P., Li, C. Y., Yang, Y. J., Hung, Y. H., Cho, C. Y., Wang, C. Y., Weng, T. Y. & Lai, M. D., 2016 十一月, 於: International Journal of Oncology. 49, 5, p. 1881-1889 9 p.研究成果: Article › 同行評審
17 引文 斯高帕斯(Scopus) -
Differential expression pattern of THBS1 and THBS2 in lung cancer: Clinical outcome and a systematic-analysis of microarray databases
Weng, T. Y., Wang, C. Y., Hung, Y. H., Chen, W. C., Chen, Y. L. & Lai, M. D., 2016 八月, 於: PloS one. 11, 8, e0161007.研究成果: Article › 同行評審
24 引文 斯高帕斯(Scopus) -
Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia
Chen, M. C., Chen, Y. L., Wang, T. W., Hsu, H. P. & Lai, M. D., 2016 十月, 於: Oncology Reports. 36, 4, p. 1997-2008 12 p.研究成果: Article › 同行評審
10 引文 斯高帕斯(Scopus) -
MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer
Cho, C. Y., Lee, K. T., Chen, W. C., Wang, C. Y., Chang, Y. S., Huang, H. L., Hsu, H. P., Yen, M. C., Lai, M. Z. & Lai, M. D., 2016 三月 22, 於: Oncotarget. 7, 12, p. 14586-14604 19 p.研究成果: Article › 同行評審
16 引文 斯高帕斯(Scopus) -
Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells
Chu, P. C., Yang, M. C., Kulp, S. K., Salunke, S. B., Himmel, L. E., Fang, C. S., Jadhav, A. M., Shan, Y. S., Lee, C. T., Lai, M. D., Shirley, L. A., Bekaii-Saab, T. & Chen, C. S., 2016 七月 28, 於: Oncogene. 35, 30, p. 3897-3908 12 p.研究成果: Article › 同行評審
19 引文 斯高帕斯(Scopus) -
Systematic analysis of gene expression alterations and clinical outcomes for long-chain acyl-coenzyme A synthetase family in cancer
Chen, W. C., Wang, C. Y., Hung, Y. H., Weng, T. Y., Yen, M. C. & Lai, M. D., 2016 五月 1, 於: PloS one. 11, 5, e0155660.研究成果: Article › 同行評審
46 引文 斯高帕斯(Scopus) -
2014
A novel cancer therapeutic using thrombospondin 1 in dendritic cells
Weng, T. Y., Huang, S. S., Yen, M. C., Lin, C. C., Chen, Y. L., Lin, C. M., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 二月, 於: Molecular Therapy. 22, 2, p. 292-302 11 p.研究成果: Article › 同行評審
15 引文 斯高帕斯(Scopus) -
DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model
Weng, T. Y., Yen, M. C., Huang, C. T., Hung, J. J., Chen, Y. L., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 一月 1, 於: Gene Therapy. 21, 10, p. 888-896 9 p.研究成果: Article › 同行評審
10 引文 斯高帕斯(Scopus) -
Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma
Hung, Y. U. H., Chan, Y. I. S., Chang, Y. S., Lee, K. T., Hsu, H. P., Yen, M. C., Chen, W. C., Wang, C. Y. & Lai, M. D., 2014 六月, 於: Oncology Reports. 31, 6, p. 2797-2803 7 p.研究成果: Article › 同行評審
16 引文 斯高帕斯(Scopus) -
Hypoxia promotes nuclear translocation and transcriptional function in the oncogenic tyrosine kinase RON
Chang, H. Y., Liu, H. S., Lai, M. D., Tsai, Y. S., Tzai, T. S., Cheng, H. L. & Chow, N. H., 2014 八月 15, 於: Cancer Research. 74, 16, p. 4549-4562 14 p.研究成果: Article › 同行評審
24 引文 斯高帕斯(Scopus) -
Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease
Wang, S. M., Lee, Y. C., Ko, C. Y., Lai, M. D., Lin, D. Y., Pao, P. C., Chi, J. Y., Hsiao, Y. W., Liu, T. L. & Wang, J. M., 2014 二月, 於: Molecular Neurobiology. 51, 1, p. 370-382 13 p.研究成果: Article › 同行評審
27 引文 斯高帕斯(Scopus) -
Induction of indoleamine 2,3-dioxygenase (IDO) enzymatic activity contributes to interferon-gamma induced apoptosis and death receptor 5 expression in human non-small cell lung cancer cells
Chung, T. W., Tan, K. T., Chan, H. L., Lai, M. D., Yen, M. C., Li, Y. R., Lin, S. H. & Lin, C. C., 2014, 於: Asian Pacific Journal of Cancer Prevention. 15, 18, p. 7995-8001 7 p.研究成果: Article › 同行評審
10 引文 斯高帕斯(Scopus) -
Optimization protein productivity of human interleukin-2 through codon usage, gene copy number and intracellular tRNA concentration in CHO cells
Ou, K. C., Wang, C. Y., Liu, K. T., Chen, Y. L., Chen, Y. C., Lai, M. D. & Yen, M. C., 2014 十一月 14, 於: Biochemical and Biophysical Research Communications. 454, 2, p. 347-352 6 p.研究成果: Article › 同行評審
10 引文 斯高帕斯(Scopus) -
Potential significance of EMP3 in patients with upper urinary tract urothelial carcinoma: Crosstalk with ErbB2-PI3K-Akt pathway
Wang, Y. W., Li, W. M., Wu, W. J., Chai, C. Y., Liu, H. S., Lai, M. D. & Chow, N. H., 2014 七月, 於: Journal of Urology. 192, 1, p. 242-251 10 p.研究成果: Article › 同行評審
16 引文 斯高帕斯(Scopus) -
Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model
Shan, Y. S., Hsu, H. P., Lai, M. D., Yen, M. C., Fang, J. H., Weng, T. Y. & Chen, Y. L., 2014 十二月 1, 於: Oncology Reports. 32, 6, p. 2335-2342 8 p.研究成果: Article › 同行評審
15 引文 斯高帕斯(Scopus) -
2013
An HDAC inhibitor enhances cancer therapeutic efficiency of RNA polymerase III promoter-driven IDO shRNA
Yen, M. C., Weng, T. Y., Chen, Y. L., Lin, C. C., Chen, C. Y., Wang, C. Y., Chao, H. L., Chen, C. S. & Lai, M. D., 2013 六月 1, 於: Cancer Gene Therapy. 20, 6, p. 351-357 7 p.研究成果: Article › 同行評審
5 引文 斯高帕斯(Scopus) -
Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide
Huang, H. L., Hsu, H. P., Shieh, S. C., Chang, Y. S., Chen, W. C., Cho, C. Y., Teng, C. F., Su, I. J., Hung, W. C. & Lai, M. D., 2013 十一月, 於: Molecular cancer therapeutics. 12, 11, p. 2505-2516 12 p.研究成果: Article › 同行評審
17 引文 斯高帕斯(Scopus) -
Biolistic DNA delivery to mice with the low pressure gene gun
Yen, M. C. & Lai, M. D., 2013 一月 1, Biolistic DNA Delivery: Methods and Protocols. Sudowe, S. & Reske-Kunz, A. (編輯). p. 169-174 6 p. (Methods in Molecular Biology; 卷 940).研究成果: Chapter
2 引文 斯高帕斯(Scopus) -
Redox-sensitive endoplasmic reticulum stress and autophagy at rostral ventrolateral medulla contribute to hypertension in spontaneously hypertensive rats
Chao, Y. M., Lai, M. D. & Chan, J. Y. H., 2013, 於: Hypertension. 61, 6, p. 1270-1280 11 p.研究成果: Article › 同行評審
38 引文 斯高帕斯(Scopus) -
Very low-density lipoprotein/lipo-viro particles reverse lipoprotein lipase-mediated inhibition of hepatitis C virus infection via apolipoprotein C-III
Sun, H. Y., Lin, C. C., Lee, J. C., Wang, S-W., Cheng, P-N., Wu, I-C., Chang, T-T., Lai, M-D., Shieh, D-B. & Young, K-C., 2013 八月 1, 於: Gut. 62, 8, p. 1193-1203 11 p.研究成果: Article › 同行評審
27 引文 斯高帕斯(Scopus) -
2012
Aberrant cyclin a expression and centrosome overduplication induced by hepatitis B virus pre-S2 mutants and its implication in hepatocarcinogenesis
Wang, L. H. C., Huang, W., Lai, M. D. & Su, I. J., 2012 二月 1, 於: Carcinogenesis. 33, 2, p. 466-472 7 p.研究成果: Article › 同行評審
40 引文 斯高帕斯(Scopus) -
Endoplasmic reticulum stress stimulates p53 expression through NF-κB activation
Lin, W. C., Chuang, Y. C., Chang, Y. S., Lai, M. D., Teng, Y. N., Su, I. J., Wang, C. C. C., Lee, K. H. & Hung, J. H., 2012 七月 30, 於: PloS one. 7, 7, e39120.研究成果: Article › 同行評審
75 引文 斯高帕斯(Scopus) -
2011
ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells
Chang, Y. S., Tsai, C. T., Huangfu, C. A., Huang, W. Y., Lei, H. Y., Lin, C. F., Su, I. J., Chang, W. T., Wu, P. H., Chen, Y. T., Hung, J. H., Young, K. C. & Lai, M. D., 2011 三月 1, 於: Journal of Cellular Biochemistry. 112, 3, p. 881-893 13 p.研究成果: Article › 同行評審
30 引文 斯高帕斯(Scopus) -
Amelioration of rat collagen-induced arthritis through CD4+ T cells apoptosis and synovial interleukin-17 reduction by indoleamine 2,3-dioxygenase gene therapy
Chen, S. Y., Wu, C. L., Lai, M. D., Lin, C. C., Yo, Y. T., Jou, I. M., Lee, C. H., Weng, C. T., Shiau, A. L. & Wang, C. R., 2011 二月 1, 於: Human Gene Therapy. 22, 2, p. 145-154 10 p.研究成果: Article › 同行評審
26 引文 斯高帕斯(Scopus) -
Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules
Shan, Y-S., Fang, J. H., Lai, M-D., Yen, M. C., Lin, P. W., Hsu, H-P., Lin, C. Y. & Chen, Y. L., 2011 十月 1, 於: Molecular Carcinogenesis. 50, 10, p. 739-750 12 p.研究成果: Article › 同行評審
12 引文 斯高帕斯(Scopus) -
Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein
Lee, J. W., Liao, P. C., Young, K. C., Chang, C. L., Chen, S. S. L., Chang, T. T., Lai, M. D. & Wang, S. W., 2011 十月 7, 於: Journal of Proteome Research. 10, 10, p. 4522-4534 13 p.研究成果: Article › 同行評審
30 引文 斯高帕斯(Scopus) -
RNAi compound targeted to thrombospondin-1 and applications thereof
Lai, M-D., 2011 七月 7, 專利號 8377902研究成果: Patent
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Skin delivery of short hairpin RNA of indoleamine 2,3 dioxygenase induces antitumor immunity against orthotopic and metastatic liver cancer
Huang, T. T., Yen, M. C., Lin, C. C., Weng, T. Y., Chen, Y. L., Lin, C. M. & Lai, M. D., 2011 十二月, 於: Cancer Science. 102, 12, p. 2214-2220 7 p.研究成果: Article › 同行評審
25 引文 斯高帕斯(Scopus)