A novel ultra-wideband (UWB) bandpass filter with 5 to 6 GHz rejection band is proposed. The multiple coupled line structure is incorporated with multiple-mode resonator (MMR) to provide wide transmission band and enhance out-of band performance. To inhibit the signals ranged from 5- to 6-GHz, four stepped-impedance open stubs are implemented on the MMR without increasing the size of the proposed filter. The design of the proposed UWB filter has two transmission bands. The first passband from 2.8 GHz to 5 GHz has less than 2 dB insertion loss and greater than 18 dB return loss. The second passband within 6 GHz and 10.6 GHz has less than 1.5 dB insertion loss and greater than 15 dB return loss. The rejection at 5.5 GHz is better than 50 dB. This filter can be integrated in UWB radio systems and efficiently enhance the interference immunity from WLAN.