A capillary dielectrophoretic chip for real-time blood cell separation from a drop of whole blood

Shu Hsien Liao, Ching Yu Chang, Hsien Chang Chang

研究成果: Article同行評審

28 引文 斯高帕斯(Scopus)

摘要

This study proposes a capillary dielectrophoretic chip to separate blood cells from a drop of whole blood (approximately 1 μl) sample using negative dielectrophoretic force. The separating efficiency was evaluated by analyzing the image before and after dielectrophoretic force manipulation. Blood samples with various hematocrits (10%-60%) were tested with varied separating voltages and chip designs. In this study, a chip with 50 μm gap design achieved a separation efficiency of approximately 90% within 30 s when the hematocrit was in the range of 10%-50%. Furthermore, glucose concentration was electrochemically measured by separating electrodes following manipulation. The current response increased significantly (8.8-fold) after blood cell separation, which was attributed not only to the blood cell separation but also to sample disturbance by the dielectrophoretic force.

原文English
文章編號024110
期刊Biomicrofluidics
7
發行號2
DOIs
出版狀態Published - 2013 四月 5

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics
  • Fluid Flow and Transfer Processes
  • Colloid and Surface Chemistry

指紋 深入研究「A capillary dielectrophoretic chip for real-time blood cell separation from a drop of whole blood」主題。共同形成了獨特的指紋。

引用此