A cellular ELISA to screen lectin-like compounds for cancer cell binding

C. P. Chang, W. C. Cheng, H. Y. Lei

研究成果: Article同行評審

2 引文 斯高帕斯(Scopus)

摘要

Lectins are carbohydrate-binding proteins that can modulate cellular activity through cell membrane glycoproteins. A cell-based binding was set up to screen the lectin-like substances in natural products. Lectins, after binding to tumor cells, are detected with a biotinylated carbohydrate-polyacrylamide complex by ELISA. Sugar specificity can also be determined within the assay.

原文English
頁(從 - 到)182-188
頁數7
期刊Letters in Drug Design and Discovery
2
發行號3
DOIs
出版狀態Published - 2005 五月

All Science Journal Classification (ASJC) codes

  • 分子醫學
  • 藥學科學
  • 藥物發現

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