A developed quantitative measurement using the electro-microchip for Methamphetamine detection

Chia Hsien Yeh, Wei Ting Wang, Yu-Cheng Lin, Pi Lan Shen

研究成果: Conference contribution

1 引文 斯高帕斯(Scopus)

摘要

In this study, an electro-microchip was successfully used to detect the impedance signals of various Methamphetamine (MET) concentrations based on the developed competitive-immunoassay method. MET is a commonly used drug often abused by drug addicts and can cause irregular behavior; therefore, MET concentration detection is important for quantitative analysis. In this study, the gold nanoparticles (AuNPs) were introduced into an electro-microchip through the specific binding of antibodies, thus constructing a bridge between two electrodes allowing electrons to move between them. When the concentration of the anti-MET antibody-colloidal gold conjugates was diluted 100 times, the detectable limit for MET concentration was 1 ng/mL with 0.5 μg/mL of BSA-MET conjugate. Therefore, the developed electro-microchip is advantageous because it is effective with small sample volumes (30 μL), is a form of rapid quantitative measurement, and works with smaller detectable concentrations than other existing commercial detection products which have the best limit of detection of 100 ng/mL.

原文English
主出版物標題IEEE SENSORS 2012 - Proceedings
DOIs
出版狀態Published - 2012 十二月 1
事件11th IEEE SENSORS 2012 Conference - Taipei, Taiwan
持續時間: 2012 十月 282012 十月 31

出版系列

名字Proceedings of IEEE Sensors

Other

Other11th IEEE SENSORS 2012 Conference
國家Taiwan
城市Taipei
期間12-10-2812-10-31

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

指紋 深入研究「A developed quantitative measurement using the electro-microchip for Methamphetamine detection」主題。共同形成了獨特的指紋。

引用此