A linear gradient line source facilitates the use of diffusion models with high order approximation for efficient, accurate turbid sample optical properties recovery

Ming Wei Lee, Cheng Hung Hung, Jung Li Liao, Nan Yu Cheng, Ming Feng Hou, Sheng Hao Tseng

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)

摘要

In this paper, we demonstrate that a scanning MEMS mirror can be employed to create a linear gradientline source that is equivalent to a planar source. This light source setup facilitates the use of diffusion models of increased orders of approximation having closed form solution, and thus enhance the efficiency and accuracy insample optical properties recovery. In addition, compared with a regular planar light source, the linear gradient line source occupies much less source area and has an elevated measurement efficiency. We employed a δ-P1 diffusion equation with a closed form solution and carried out a phantom study to understand the performance of this new method in determining the absorption and scattering properties of turbid samples. Moreover, our Monte Carlo simulation results indicated that this geometry had probing depths comparable to those of the conventional diffuse reflectance measurement geometry with a source-detector separation of 3 mm. We expect that this new source setup would facilitate the investigating of superficial volumes of turbid samples in the wavelength regions where tissue absorption coefficients are comparable to scattering coefficients.

原文English
頁(從 - 到)3628-3639
頁數12
期刊Biomedical Optics Express
5
發行號10
DOIs
出版狀態Published - 2014 十月 1

All Science Journal Classification (ASJC) codes

  • 生物技術
  • 原子與分子物理與光學

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