Meander line antenna (MLA) is designed for biomedical band antenna because their low profile and relative high efficiency. This work present a new methods of impedance matching on meander line antenna. In this design has proposed a Planar Inverted-F Antenna (PIFA) short pin structure design, based on a meander line shaped on 433 MHz which is ISM band. According to this method, the resonant characteristics of MLA are related to their physical dimension such as meander height, width number of folds, their positions and overall length of the structure. The antenna has been test with the Vector Network Analyzer and the resonance frequency is measured at 431 MHz, with a meander of 5.5 turns and matching meander 7.5 turns. The best return loss for the antenna is 28dB (measured) with a gain of -3.3 dBi.