A microfluidic-based cell culture platform for cellular and subcellular imaging

Dar-Bin Shieh, Chia Chun Hsieh, Song Bin Huang, Gwo Bin Lee

研究成果: Conference contribution

1 引文 斯高帕斯(Scopus)

摘要

This study reports a new microfluidic-based cell culture platform. Moreover, microheaters, a micro temperature sensor, micropumps were integrated into the system to achieve a self-contained device for standard perfusion mammalian cell culture. One of key features of the proposed platform is the design of ultra-thin cell culture chamber allowing real-time cellular and sub-cellular imaging. The entire cell culture process can be performed automatically without human intervention. The developed platform was used for study of drug delivery on oral cancer cells. Experimental data showed that it can successfully monitor the dividing process of cancer cells. Besides, the cell response to anti-cancer drugs was also investigated. The developed platform can be promising for cell-based study.

原文English
主出版物標題4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009
頁面223-226
頁數4
DOIs
出版狀態Published - 2009 十月 12
事件4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009 - Shenzhen, China
持續時間: 2009 一月 52009 一月 8

出版系列

名字4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009

Other

Other4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009
國家China
城市Shenzhen
期間09-01-0509-01-08

    指紋

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

引用此

Shieh, D-B., Hsieh, C. C., Huang, S. B., & Lee, G. B. (2009). A microfluidic-based cell culture platform for cellular and subcellular imaging. 於 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009 (頁 223-226). [5068564] (4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009). https://doi.org/10.1109/NEMS.2009.5068564